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Index CTCF

Transcriptional repressor CTCF also known as 11-zinc finger protein or CCCTC-binding factor is a transcription factor that in humans is encoded by the CTCF gene. [1]

21 relations: ChIP-sequencing, Chromatin, Chromatin immunoprecipitation, Cohesin, Consensus sequence, DNA methylation, Gene, H19 (gene), Insulator (genetics), Insulin-like growth factor 2, KCNQ1OT1, Myc, Nuclear lamina, Nucleic acid notation, Protein dimer, Protein–protein interaction, Regulation of gene expression, Transcription factor, V(D)J recombination, Y box binding protein 1, Zinc finger.


ChIP-sequencing, also known as ChIP-seq, is a method used to analyze protein interactions with DNA.

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Chromatin is a complex of macromolecules found in cells, consisting of DNA, protein, and RNA.

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Chromatin immunoprecipitation

Chromatin immunoprecipitation (ChIP) is a type of immunoprecipitation experimental technique used to investigate the interaction between proteins and DNA in the cell.

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Cohesin is a protein complex that regulates the separation of sister chromatids during cell division, either mitosis or meiosis.

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Consensus sequence

In molecular biology and bioinformatics, the consensus sequence (or canonical sequence) is the calculated order of most frequent residues, either nucleotide or amino acid, found at each position in a sequence alignment.

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DNA methylation

DNA methylation is a process by which methyl groups are added to the DNA molecule.

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In biology, a gene is a sequence of DNA or RNA that codes for a molecule that has a function.

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H19 (gene)

H19 is a gene for a long noncoding RNA, found in humans and elsewhere.

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Insulator (genetics)

An insulator is a type of cis-regulatory element known as a long-range regulatory element.

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Insulin-like growth factor 2

Insulin-like growth factor 2 (IGF-2) is one of three protein hormones that share structural similarity to insulin.

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KCNQ1 overlapping transcript 1, also known as KCNQ1OT1, is a long non-coding RNA gene found in the KCNQ1 locus.

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Myc is a family of regulator genes and proto-oncogenes that code for transcription factors.

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Nuclear lamina

The nuclear lamina is a dense (~30 to 100 nm thick) fibrillar network inside the nucleus of most cells.

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Nucleic acid notation

The nucleic acid notation currently in use was first formalized by the International Union of Pure and Applied Chemistry (IUPAC) in 1970.

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Protein dimer

In biochemistry, a protein dimer is a macromolecular complex formed by two protein monomers, or single proteins, which are usually non-covalently bound.

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Protein–protein interaction

Protein–protein interactions (PPIs) are the physical contacts of high specificity established between two or more protein molecules as a result of biochemical events steered by electrostatic forces including the hydrophobic effect.

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Regulation of gene expression

Regulation of gene expression includes a wide range of mechanisms that are used by cells to increase or decrease the production of specific gene products (protein or RNA), and is informally termed gene regulation.

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Transcription factor

In molecular biology, a transcription factor (TF) (or sequence-specific DNA-binding factor) is a protein that controls the rate of transcription of genetic information from DNA to messenger RNA, by binding to a specific DNA sequence.

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V(D)J recombination

V(D)J recombination is the unique mechanism of genetic recombination that occurs only in developing lymphocytes during the early stages of T and B cell maturation.

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Y box binding protein 1

Y box binding protein 1 also known as Y-box transcription factor or nuclease-sensitive element-binding protein 1 is a protein that in humans is encoded by the YBX1 gene.

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Zinc finger

A zinc finger is a small protein structural motif that is characterized by the coordination of one or more zinc ions (Zn2+) in order to stabilize the fold.

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CTCF (gene).


[1] https://en.wikipedia.org/wiki/CTCF

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