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GVAX

Index GVAX

GVAX is a cancer vaccine composed of whole tumor cells genetically modified to secrete the immune stimulatory cytokine, granulocyte-macrophage colony-stimulating factor (GM-CSF), and then irradiated to prevent further cell division. [1]

Table of Contents

  1. 9 relations: Allotransplantation, Autotransplantation, Berkeley, California, Cancer vaccine, Cytokine, Granulocyte-macrophage colony-stimulating factor, Pancreatic cancer, Programmed cell death protein 1, Whitehead Institute.

Allotransplantation

Allotransplant (allo- meaning "other" in Greek) is the transplantation of cells, tissues, or organs to a recipient from a genetically non-identical donor of the same species.

See GVAX and Allotransplantation

Autotransplantation

Autotransplantation is the transplantation of organs, tissues, or even particular proteins from one part of the body to another in the same person (auto- meaning "self" in Greek).

See GVAX and Autotransplantation

Berkeley, California

Berkeley is a city on the eastern shore of San Francisco Bay in northern Alameda County, California, United States.

See GVAX and Berkeley, California

Cancer vaccine

A cancer vaccine, or oncovaccine, is a vaccine that either treats existing cancer or prevents development of cancer.

See GVAX and Cancer vaccine

Cytokine

Cytokines are a broad and loose category of small proteins (~5–25 kDa) important in cell signaling.

See GVAX and Cytokine

Granulocyte-macrophage colony-stimulating factor

Granulocyte-macrophage colony-stimulating factor (GM-CSF), also known as colony-stimulating factor 2 (CSF2), is a monomeric glycoprotein secreted by macrophages, T cells, mast cells, natural killer cells, endothelial cells and fibroblasts that functions as a cytokine.

See GVAX and Granulocyte-macrophage colony-stimulating factor

Pancreatic cancer

Pancreatic cancer arises when cells in the pancreas, a glandular organ behind the stomach, begin to multiply out of control and form a mass.

See GVAX and Pancreatic cancer

Programmed cell death protein 1

Programmed cell death protein 1 (PD-1), (CD279 cluster of differentiation 279).

See GVAX and Programmed cell death protein 1

Whitehead Institute

Whitehead Institute for Biomedical Research is a non-profit research institute located in Cambridge, Massachusetts, United States that is dedicated to improving human health through basic biomedical research.

See GVAX and Whitehead Institute

References

[1] https://en.wikipedia.org/wiki/GVAX