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Phenformin is an antidiabetic drug from the biguanide class. [1]

10 relations: AMP-activated protein kinase, Anti-diabetic medication, Biguanide, Buformin, Cimetidine, Lactic acidosis, Mechanistic target of rapamycin, Metformin, Ralph Nader, Seymour Shapiro.

AMP-activated protein kinase

5' AMP-activated protein kinase or AMPK or 5' adenosine monophosphate-activated protein kinase is an enzyme that plays a role in cellular energy homeostasis.

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Anti-diabetic medication

Drugs used in diabetes treat diabetes mellitus by lowering glucose levels in the blood.

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Biguanide is the organic compound with the formula HN(C(NH)NH2)2.

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Buformin (1-butylbiguanide) is an oral antidiabetic drug of the biguanide class, chemically related to metformin and phenformin.

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Cimetidine INN is a histamine H2-receptor antagonist that inhibits stomach acid production. It is largely used in the treatment of heartburn and peptic ulcers. It has been marketed by GlaxoSmithKline (which is selling the brand to Prestige Brands) under the trade name Tagamet (sometimes Tagamet HB or Tagamet HB200). Cimetidine was approved in the UK in 1976, and was approved in the US by the Food and Drug Administration for prescriptions starting January 1, 1979.

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Lactic acidosis

Lactic acidosis is a physiological condition characterized by low pH in body tissues and blood (acidosis) accompanied by the buildup of lactate, especially L-lactate, and is considered a distinct form of metabolic acidosis.

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Mechanistic target of rapamycin

The mechanistic target of rapamycin, also known as mammalian target of rapamycin (mTOR) or FK506-binding protein 12-rapamycin-associated protein 1 (FRAP1), is a protein that in humans is encoded by the MTOR gene.

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Metformin, marketed under the tradename Glucophage among others, is an antidiabetic medication which is taken by mouth.

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Ralph Nader

Ralph Nader (born February 27, 1934) is an American political activist, as well as an author, lecturer, and attorney.

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Seymour Shapiro

Seymour Lester Shapiro (1916 - 1961) was an organic chemist best known for his pioneering work on a class of drugs used to treat symptoms of adult-onset diabetes.

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ATC code A10BA01, ATCvet code QA10BA01, Azucaps, C10H15N5, Cronoformin, D Bretard, DB Comb, DB-Retard, Debeone, Debinyl, Diabis, Dibein, Dibiraf, Dibotin, Dipar, Feguanide, Fenfoduron, Fenformin, Fenformine, Fenormin, Glukopostin, Glyphen, Insoral, Lentobetic, Meltrol, Meltrol-50, Normoglucina, Phenethylbiguanide, Phenformin hydrochlorite, Phenformine, Phenformix, Pherformin, Retardo.


[1] https://en.wikipedia.org/wiki/Phenformin

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