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18-Methylsegesterone acetate

Index 18-Methylsegesterone acetate

18-Methylsegesterone acetate (18-methyl-SGA; also known as 18-methylnestorone) is a progestin medication of the 19-norprogesterone group which was never marketed. [1]

28 relations: Androgen receptor, Binding selectivity, Bioassay, Bioavailability, Derivative (chemistry), Ethyl group, Levonorgestrel, Ligand (biochemistry), Methyl group, Modified-release dosage, Nandrolone, Norethisterone, Oral administration, Patent, Potency (pharmacology), Pregnancy, Progesterone (medication), Progesterone receptor, Progestin, Progestogen, Progestogen ester, Route of administration, Segesterone acetate, Steroid hormone receptor, Subcutaneous implant, Transdermal patch, Uterus, 19-Norprogesterone.

Androgen receptor

The androgen receptor (AR), also known as NR3C4 (nuclear receptor subfamily 3, group C, member 4), is a type of nuclear receptor that is activated by binding any of the androgenic hormones, including testosterone and dihydrotestosterone in the cytoplasm and then translocating into the nucleus.

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Binding selectivity

Binding selectivity is defined with respect to the binding of ligands to a substrate forming a complex.

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Bioassay

A bioassay is an analytical method to determine concentration or potency of a substance by its effect on living cells or tissues.

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Bioavailability

In pharmacology, bioavailability (BA or F) is a subcategory of absorption and is the fraction of an administered dose of unchanged drug that reaches the systemic circulation, one of the principal pharmacokinetic properties of drugs.

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Derivative (chemistry)

In chemistry, a derivative is a compound that is derived from a similar compound by a chemical reaction.

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Ethyl group

In chemistry, an ethyl group is an alkyl substituent derived from ethane (C2H6).

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Levonorgestrel

Levonorgestrel is a hormonal medication which is used in a number of birth control methods.

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Ligand (biochemistry)

In biochemistry and pharmacology, a ligand is a substance that forms a complex with a biomolecule to serve a biological purpose.

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Methyl group

A methyl group is an alkyl derived from methane, containing one carbon atom bonded to three hydrogen atoms — CH3.

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Modified-release dosage

Modified-release dosage is a mechanism that (in contrast to immediate-release dosage) delivers a drug with a delay after its administration (delayed-release dosage) or for a prolonged period of time (extended-release dosage) or to a specific target in the body (targeted-release dosage).

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Nandrolone

Nandrolone, also known as 19-nortestosterone, is an androgen and anabolic steroid (AAS) which is used in the form of esters such as nandrolone decanoate (brand name Deca-Durabolin) and nandrolone phenylpropionate (brand name Durabolin).

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Norethisterone

Norethisterone, also known as norethindrone and sold under the brand names Aygestin and Primolut N among many others, is a progestin medication which is used in birth control pills, menopausal hormone therapy, and for the treatment of gynecological disorders.

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Oral administration

| name.

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Patent

A patent is a set of exclusive rights granted by a sovereign state or intergovernmental organization to an inventor or assignee for a limited period of time in exchange for detailed public disclosure of an invention.

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Potency (pharmacology)

In the field of pharmacology, potency is a measure of drug activity expressed in terms of the amount required to produce an effect of given intensity.

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Pregnancy

Pregnancy, also known as gestation, is the time during which one or more offspring develops inside a woman.

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Progesterone (medication)

Progesterone is a medication and naturally occurring steroid hormone.

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Progesterone receptor

The progesterone receptor (PR), also known as NR3C3 or nuclear receptor subfamily 3, group C, member 3, is a protein found inside cells.

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Progestin

A progestin is a type of medication which is used most commonly in hormonal birth control and menopausal hormone therapy.

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Progestogen

Progestogens, also sometimes spelled progestagens or gestagens, are a class of steroid hormones that bind to and activate the progesterone receptor (PR).

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Progestogen ester

A progestogen ester is an ester of a progestogen or progestin (a synthetic progestogen).

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Route of administration

A route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body.

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Segesterone acetate

Segesterone acetate (SGA), sold under the brand names Nestorone and Elcometrine, is a progestin medication which is used in birth control and in the treatment of endometriosis in Brazil and other South American countries.

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Steroid hormone receptor

Steroid hormone receptors are found in the nucleus, cytosol, and also on the plasma membrane of target cells.

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Subcutaneous implant

In medicine, a subcutaneous implant, or subcutaneous pellet, is an implant that is delivered under the skin into the subcutaneous tissue by surgery or injection and is used to deliver a drug for a long period of time.

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Transdermal patch

A transdermal patch is a medicated adhesive patch that is placed on the skin to deliver a specific dose of medication through the skin and into the bloodstream.

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Uterus

The uterus (from Latin "uterus", plural uteri) or womb is a major female hormone-responsive secondary sex organ of the reproductive system in humans and most other mammals.

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19-Norprogesterone

19-Norprogesterone, also known as 19-norpregn-4-ene-3,20-dione, is a steroidal progestin and close analogue of the sex hormone progesterone, lacking only the C19 methyl group of that molecule.

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Redirects here:

13-Ethyl-NES, 13-Ethyl-SGA, 13-Ethyl-nestorone, 13-Ethylnestorone, 13-ethyl-NES, 13-ethyl-SGA, 13-ethyl-nestoron, 13-ethyl-nestorone, 13-ethylnestoron, 13-ethylnestorone, 13β-Ethyl-NES, 13β-Ethyl-SGA, 13β-Ethyl-elcometrine, 13β-Ethyl-nestoron, 13β-Ethyl-nestorone, 13β-Ethylelcometrine, 13β-Ethylnestorone, 13β-ethyl-NES, 13β-ethyl-SGA, 13β-ethyl-elcometrine, 13β-ethyl-nestoron, 13β-ethyl-nestorone, 13β-ethylelcometrine, 13β-ethylnestorone, 18-Methyl-NES, 18-Methyl-SGA, 18-Methyl-elcometrine, 18-Methyl-nestoron, 18-Methyl-nestorone, 18-Methylelcometrine, 18-Methylnestoron, 18-Methylnestorone, 18-methyl-NES, 18-methyl-SGA, 18-methyl-elcometrine, 18-methyl-nestoron, 18-methyl-nestorone, 18-methylelcometrine, 18-methylnestoron, 18-methylnestorone, 18-methylsegesterone acetate, Ethyl-NES, Ethyl-elcometrine, Ethyl-nestoron, Ethyl-nestorone, Ethylelcometrine, Ethylnestoron, Ethylnestorone, Methyl-NES, Methyl-elcometrine, Methyl-nestoron, Methyl-nestorone, Methylelcometrine, Methylnestoron, Methylnestorone, Methylsegesterone acetate.

References

[1] https://en.wikipedia.org/wiki/18-Methylsegesterone_acetate

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