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Hoffmann-La Roche

Index Hoffmann-La Roche

F. [1]

130 relations: Acitretin, Afucosylated monoclonal antibodies, Aktiengesellschaft, Alectinib, Allergan, Basel, Benserazide, Benzodiazepine, Bevacizumab, Bromazepam, Burlington, North Carolina, Calcitriol, Cancer, Capecitabine, Carvedilol, Ceftriaxone, Chairman, Chief executive officer, Chief Medical Officer, Christoph Franz, Chronic lymphocytic leukemia, Chugai Pharmaceutical Co., Cilazapril, Clifton, New Jersey, Clonazepam, Cobas Mira, Competition law, Daclizumab, Diagnosis, Diagnosis of HIV/AIDS, Diazepam, DNA sequencing, Dornase alfa, Enfuvirtide, Enprostil, Epoetin beta, Erlotinib, European Commission, European Economic Community, European Federation of Pharmaceutical Industries and Associations, Filgrastim, Flumazenil, Flunitrazepam, Flurazepam, Foundation Medicine, Fritz Hoffmann-La Roche, Ganciclovir, Genentech, Gilead Sciences, Granisetron, ..., Holding company, Ibandronic acid, Influenza A virus subtype H5N1, Innovative Medicines Initiative, International Society for Pharmaceutical Engineering, Iproniazid, Isoniazid, Isotretinoin, Ketorolac, L-DOPA, LabCorp, List of pharmaceutical companies, Management of HIV/AIDS, Medication, Mefloquine, Methods in Molecular Biology, Methoxy polyethylene glycol-epoetin beta, Midazolam, Moclobemide, Multinational corporation, Multivitamin, Mycophenolic acid, Naproxen, Nicardipine, Nonsteroidal anti-inflammatory drug, Novartis, Nutley, New Jersey, Obinutuzumab, Olesoxime, Orlistat, Oseltamivir, Patent, Pegfilgrastim, Peginterferon alfa-2a, Pharmaceutical industry, Pharmaceutical industry in Switzerland, Polychlorinated dibenzodioxins, Polymerase chain reaction, Pre-clinical development, Price fixing, Procedural sedation and analgesia, Ranibizumab, Red Herring (magazine), Redoxon, Research and development, Reuters, Rituximab, Roche Diagnostics, Salvage therapy, Saquinavir, Severin Schwan, Seveso, Seveso disaster, SIX Swiss Exchange, South San Francisco, California, Spinal muscular atrophy, Stanley Adams (whistleblower), Subsidiary, Sulfadoxine/pyrimethamine, Swiss franc, Switzerland, Syntex, The New York Times, The Observer, The Times, Tocilizumab, Tranquilizer, Trastuzumab, Tretinoin, Trimethoprim/sulfamethoxazole, Trophos, Tuberculosis, Valganciclovir, Vemurafenib, Ventana Medical Systems, Vismodegib, Vitamin, Vitamin C, Warner Chilcott, 454 Life Sciences. Expand index (80 more) »

Acitretin

Acitretin (trade names Soriatane and Neotigason) is a second-generation retinoid.

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Afucosylated monoclonal antibodies

Afucosylated monoclonal antibodies are monoclonal antibodies engineered so that the oligosaccharides in the Fc region of the antibody do not have any fucose sugar units.

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Aktiengesellschaft

Aktiengesellschaft (abbreviated AG) is a German word for a corporation limited by share ownership (i.e. one which is owned by its shareholders) and may be traded on a stock market.

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Alectinib

Alectinib (INN, marketed as Alecensa) is an oral drug that blocks the activity of anaplastic lymphoma kinase (ALK) and is used to treat non-small-cell lung cancer (NSCLC).

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Allergan

Allergan plc is a multinational company in the pharmaceutical industry that produces branded drugs and performs pharmaceutical research and development.

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Basel

Basel (also Basle; Basel; Bâle; Basilea) is a city in northwestern Switzerland on the river Rhine.

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Benserazide

Benserazide (also called Serazide or Ro 4-4602) is a peripherally-acting aromatic L-amino acid decarboxylase (AADC) or DOPA decarboxylase inhibitor, which is unable to cross the blood–brain barrier.

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Benzodiazepine

Benzodiazepines (BZD, BZs), sometimes called "benzos", are a class of psychoactive drugs whose core chemical structure is the fusion of a benzene ring and a diazepine ring.

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Bevacizumab

Bevacizumab, sold under the trade name Avastin, is medication used to treat a number of types of cancers and a specific eye disease.

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Bromazepam

Bromazepam (marketed under several brand names, including Lectopam, Lexotan, Lexilium, Lexaurin, Brazepam, Rekotnil, Bromaze, Somalium and Lexotanil) is a benzodiazepine derivative drug, patented by Roche in 1963 and developed clinically in the 1970s.

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Burlington, North Carolina

Burlington is a city in Alamance and Guilford counties in the U.S. state of North Carolina.

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Calcitriol

Calcitriol (INN), also called 1,25-dihydroxycholecalciferol, or 1alpha,25-dihydroxyvitamin D3, 1,25-dihydroxyvitamin D3 and other variants, is the hormonally active metabolite of vitamin D which has three hydroxyl groups.

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Cancer

Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body.

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Capecitabine

Capecitabine, sold under the brand name Xeloda among others, is a chemotherapy medication used to treat breast cancer, gastric cancer and colorectal cancer.

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Carvedilol

Carvedilol, sold under the brand name Coreg among others, is a medication used for treating mild to severe congestive heart failure (CHF), left ventricular dysfunction (LVD) following heart attack in people who are otherwise stable, and for treating high blood pressure.

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Ceftriaxone

Ceftriaxone, sold under the trade name Rocephin, is an antibiotic useful for the treatment of a number of bacterial infections.

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Chairman

The chairman (also chairperson, chairwoman or chair) is the highest officer of an organized group such as a board, a committee, or a deliberative assembly.

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Chief executive officer

Chief executive officer (CEO) is the position of the most senior corporate officer, executive, administrator, or other leader in charge of managing an organization especially an independent legal entity such as a company or nonprofit institution.

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Chief Medical Officer

Chief Medical Officer (CMO) is the title used in many countries for the senior government official designated head of medical services, sometimes at the national level.

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Christoph Franz

Christoph Franz (born 2 May 1960 in Frankfurt) was Chief Executive Officer of Lufthansa until 1 May 2014 (replaced by Carsten Spohr).

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Chronic lymphocytic leukemia

Chronic lymphocytic leukemia (CLL) is a type of cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell).

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Chugai Pharmaceutical Co.

is a subsidiary drug manufacturer operating in Japan controlled by Hoffmann–La Roche, which owns 62% of the company as of 30 June 2014.

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Cilazapril

Cilazapril is an angiotensin-converting enzyme inhibitor (ACE inhibitor) used for the treatment of hypertension and congestive heart failure.

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Clifton, New Jersey

Clifton is a city in Passaic County, New Jersey, United States.

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Clonazepam

Clonazepam, sold under the brand name Klonopin among others, is a medication used to prevent and treat seizures, panic disorder, and for the movement disorder known as akathisia.

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Cobas Mira

The Roche Cobas Mira, now discontinued by Roche, is a benchtop, random access biochemistry analyzer.

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Competition law

Competition law is a law that promotes or seeks to maintain market competition by regulating anti-competitive conduct by companies.

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Daclizumab

Daclizumab (trade name Zinbryta, by Biogen) is a therapeutic humanized monoclonal antibody which was used for the treatment of adults with relapsing forms of multiple sclerosis (MS).

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Diagnosis

Diagnosis is the identification of the nature and cause of a certain phenomenon.

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Diagnosis of HIV/AIDS

HIV tests are used to detect the presence of the human immunodeficiency virus (HIV), the virus that causes acquired immunodeficiency syndrome (AIDS), in serum, saliva, or urine.

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Diazepam

Diazepam, first marketed as Valium, is a medicine of the benzodiazepine family that typically produces a calming effect.

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DNA sequencing

DNA sequencing is the process of determining the precise order of nucleotides within a DNA molecule.

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Dornase alfa

Dornase alfa (proprietary name Pulmozyme from Genentech) is a highly purified solution of recombinant human deoxyribonuclease I (rhDNase), an enzyme which selectively cleaves DNA.

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Enfuvirtide

Enfuvirtide (INN) is an HIV fusion inhibitor, the first of a novel class of antiretroviral drugs used in combination therapy for the treatment of HIV-1 infection.

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Enprostil

Enprostil is a synthetic prostaglandin designed to resemble dinoprostone.

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Epoetin beta

Epoetin beta (rINN) is a synthetic, recombinant form of erythropoietin, a protein that promotes the production of red blood cells.

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Erlotinib

Erlotinib hydrochloride (trade name Tarceva) is a drug used to treat non-small cell lung cancer, pancreatic cancer and several other types of cancer.

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European Commission

The European Commission (EC) is an institution of the European Union, responsible for proposing legislation, implementing decisions, upholding the EU treaties and managing the day-to-day business of the EU.

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European Economic Community

The European Economic Community (EEC) was a regional organisation which aimed to bring about economic integration among its member states.

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European Federation of Pharmaceutical Industries and Associations

The European Federation of Pharmaceutical Industries and Associations (EFPIA) is a Brussels-based trade association founded in 1978 representing the research-based pharmaceutical industry operating in Europe.

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Filgrastim

Filgrastim, sold under the brand name Neupogen among others, is a medication used to treat low blood neutrophils.

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Flumazenil

Flumazenil (also known as flumazepil, code name Ro 15-1788) is a selective benzodiazepine receptor antagonist available by injection and intranasal.

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Flunitrazepam

Flunitrazepam, also known as Rohypnol among other names, is an intermediate acting benzodiazepine used in some countries to treat severe insomnia and in fewer, early in anesthesia.

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Flurazepam

Flurazepam (marketed under the brand names Dalmane and Dalmadorm) is a drug which is a benzodiazepine derivative.

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Foundation Medicine

Foundation Medicine, Inc. is a public American company based in Cambridge, Massachusetts which develops, manufactures and sells genomic analysis diagnostics for solid and circulating cancers.

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Fritz Hoffmann-La Roche

Fritz Hoffmann, later Fritz Hoffmann-La Roche (24 October 1868, Basel (Bâle) 18 April 1920, Basel) was the founder of Hoffmann-La Roche Ltd.

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Ganciclovir

Ganciclovir is an antiviral medication used to treat cytomegalovirus (CMV) infections.

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Genentech

Genentech, Inc., is a biotechnology corporation which became a subsidiary of Roche in 2009.

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Gilead Sciences

Gilead Sciences, Inc., commonly known as Gilead Sciences or Gilead (also styled GILEAD), is an American biopharmaceutical company that researches, develops and commercializes drugs.

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Granisetron

Granisetron is a serotonin 5-HT3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemotherapy.

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Holding company

A holding company is a company that owns other companies' outstanding stock.

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Ibandronic acid

Ibandronic acid (INN) or ibandronate sodium (USAN) is a potent bisphosphonate drug developed by Hoffman La Roche and used in the prevention and treatment of osteoporosis and metastasis-associated skeletal fractures in people with cancer.

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Influenza A virus subtype H5N1

Influenza A virus subtype H5N1, also known as A(H5N1) or simply H5N1, is a subtype of the influenza A virus which can cause illness in humans and many other animal species.

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Innovative Medicines Initiative

The Innovative Medicines Initiative (IMI) is a European initiative to improve the competitive situation of the European Union in the field of pharmaceutical research.

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International Society for Pharmaceutical Engineering

The International Society for Pharmaceutical Engineering (ISPE) is the world's largest not-for-profit association serving its members through leading scientific, technical, and regulatory advancement across the entire pharmaceutical lifecycle.

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Iproniazid

Iproniazid (Marsilid, Rivivol, Euphozid, Iprazid, Ipronid, Ipronin) is a non-selective, irreversible monoamine oxidase inhibitor (MAOI) of the hydrazine class.

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Isoniazid

Isoniazid, also known as isonicotinylhydrazide (INH), is an antibiotic used for the treatment of tuberculosis.

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Isotretinoin

Isotretinoin, also known as 13-cis-retinoic acid (and colloquially referred to by its former brand name Accutane or Roaccutane), is a medication primarily used to treat severe acne.

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Ketorolac

Ketorolac, sold under the brand name Toradol among others, is a nonsteroidal anti-inflammatory drug (NSAID) in the family of heterocyclic acetic acid derivatives, used as an analgesic.

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L-DOPA

L-DOPA, also known as levodopa or L-3,4-dihydroxyphenylalanine is an amino acid that is made and used as part of the normal biology of humans, as well as some animals and plants.

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LabCorp

Laboratory Corporation of America Holdings, more commonly known as LabCorp, is an American S&P 500 company headquartered in Burlington, North Carolina.

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List of pharmaceutical companies

It is limited to those companies notable enough to have articles in Wikipedia.

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Management of HIV/AIDS

The management of HIV/AIDS normally includes the use of multiple antiretroviral drugs in an attempt to control HIV infection.

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Medication

A medication (also referred to as medicine, pharmaceutical drug, or simply drug) is a drug used to diagnose, cure, treat, or prevent disease.

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Mefloquine

Mefloquine, sold under the brand names Lariam among others, is a medication used to prevent or treat malaria.

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Methods in Molecular Biology

Methods in Molecular Biology is a book series published by Humana Press that covers molecular biology research methods and protocols.

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Methoxy polyethylene glycol-epoetin beta

Methoxy polyethylene glycol-epoetin beta is the active ingredient of a drug marketed by Hoffmann-La Roche under the brand name Mircera.

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Midazolam

Midazolam, marketed under the trade name Versed, among others, is a medication used for anesthesia, procedural sedation, trouble sleeping, and severe agitation.

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Moclobemide

Moclobemide (sold as Amira, Aurorix, Clobemix, Depnil and Manerix) is a reversible inhibitor of monoamine oxidase A (RIMA) drug primarily used to treat depression and social anxiety. It is not approved for use in the United States, but is approved in other Western countries such as the UK and Australia (TGA approved in December 2000). It is produced by affiliates of the Hoffmann–La Roche pharmaceutical company. Initially, Aurorix was also marketed by Roche in South Africa, but was withdrawn after its patent rights expired and Cipla Medpro's Depnil and Pharma Dynamic's Clorix became available at half the cost. No significant rise in blood pressure occurs when moclobemide is combined with amines such as tyramine-containing foods or pressor amine drugs, unlike with the older nonselective and irreversible monoamine oxidase inhibitors (MAOIs), which cause a severe rise in blood pressure with such combination. Due to the lack of anticholinergic, cardiovascular, cognitive and psychomotor impairments moclobemide is advantageous in the elderly as well as those with cardiovascular disease.

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Multinational corporation

A multinational corporation (MNC) or worldwide enterprise is a corporate organization that owns or controls production of goods or services in at least one country other than its home country.

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Multivitamin

A multivitamin is a preparation intended to serve as a dietary supplement - with vitamins, dietary minerals, and other nutritional elements.

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Mycophenolic acid

Mycophenolic acid, less accurately called mycophenolate, is an immunosuppressant drug used to prevent rejection in organ transplantation.

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Naproxen

Naproxen (brand names: Aleve, Naprosyn, and many others) is a nonsteroidal anti-inflammatory drug (NSAID) of the propionic acid class (the same class as ibuprofen) that relieves pain, fever, swelling, and stiffness.

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Nicardipine

Nicardipine (Cardene) is a medication used to treat high blood pressure and angina.

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Nonsteroidal anti-inflammatory drug

Nonsteroidal anti-inflammatory drugs (NSAIDs) are a drug class that reduce pain, decrease fever, prevent blood clots and, in higher doses, decrease inflammation.

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Novartis

Novartis International AG is a Swiss multinational pharmaceutical company based in Basel, Switzerland.

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Nutley, New Jersey

Nutley is a township in Essex County, New Jersey, United States.

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Obinutuzumab

Obinutuzumab (called afutuzumab until 2009, originally GA101) is a humanized anti-CD20 monoclonal antibody, originated by GlycArt Biotechnology AG and developed by Roche as a cancer treatment.

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Olesoxime

Olesoxime (TRO19622) is an experimental neuroprotective drug.

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Orlistat

Orlistat is a drug designed to treat obesity.

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Oseltamivir

Oseltamivir, sold under the brand name Tamiflu, is an antiviral medication used to treat and prevent influenza A and influenza B (flu).

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Patent

A patent is a set of exclusive rights granted by a sovereign state or intergovernmental organization to an inventor or assignee for a limited period of time in exchange for detailed public disclosure of an invention.

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Pegfilgrastim

Pegfilgrastim is a PEGylated form of the recombinant human granulocyte colony-stimulating factor (GCSF) analog filgrastim.

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Peginterferon alfa-2a

Pegylated interferon alfa-2a, sold under the brand name Pegasys among others, is medication used to treat hepatitis C and hepatitis B. For hepatitis C it is typically used together with ribavirin and cure rates are between 24 and 92%.

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Pharmaceutical industry

The pharmaceutical industry (or medicine industry) is the commercial industry that discovers, develops, produces, and markets drugs or pharmaceutical drugs for use as different types of medicine and medications.

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Pharmaceutical industry in Switzerland

The pharmaceutical industry in Switzerland directly and indirectly employs about 135,000 people.

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Polychlorinated dibenzodioxins

Polychlorinated dibenzodioxins (PCDDs), or simply dioxins, are a group of polyhalogenated organic compounds that are significant environmental pollutants.

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Polymerase chain reaction

Polymerase chain reaction (PCR) is a technique used in molecular biology to amplify a single copy or a few copies of a segment of DNA across several orders of magnitude, generating thousands to millions of copies of a particular DNA sequence.

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Pre-clinical development

In drug development, preclinical development, also named preclinical studies and nonclinical studies, is a stage of research that begins before clinical trials (testing in humans) can begin, and during which important feasibility, iterative testing and drug safety data are collected.

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Price fixing

Price fixing is an agreement between participants on the same side in a market to buy or sell a product, service, or commodity only at a fixed price, or maintain the market conditions such that the price is maintained at a given level by controlling supply and demand.

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Procedural sedation and analgesia

Procedural sedation and analgesia, previously referred to as conscious sedation, is defined as "a technique of administering sedatives or dissociative agents with or without analgesics to induce a state that allows the patient to tolerate unpleasant procedures while maintaining cardiorespiratory function.".

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Ranibizumab

Ranibizumab (trade name Lucentis among others) is a monoclonal antibody fragment (Fab) created from the same parent mouse antibody as bevacizumab.

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Red Herring (magazine)

Red Herring is a media company that publishes an innovation magazine, an online daily technology news service, technology newsletters and hosts events for technology leaders.

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Redoxon

Redoxon was the brand name of the first artificially synthesized ascorbic acid (vitamin C).

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Research and development

Research and development (R&D, R+D, or R'n'D), also known in Europe as research and technological development (RTD), refers to innovative activities undertaken by corporations or governments in developing new services or products, or improving existing services or products.

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Reuters

Reuters is an international news agency headquartered in London, United Kingdom.

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Rituximab

Rituximab, sold under the brand name Rituxan among others, is a medication used to treat certain autoimmune diseases and types of cancer.

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Roche Diagnostics

Roche Diagnostics is a diagnostic division of Hoffmann-La Roche which manufactures equipment and reagents for research and medical diagnostic applications.

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Salvage therapy

Salvage therapy, also known as rescue therapy, is a form of therapy given after an ailment does not respond to standard therapy.

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Saquinavir

Saquinavir, sold under the brand names Invirase and Fortovase, is an antiretroviral drug used together with other medications to treat or prevent HIV/AIDS.

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Severin Schwan

Severin Schwan (born 1967) is the CEO of the Roche group, a Swiss-founded, but now global pharmaceutical company.

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Seveso

Seveso (in Lombard dialect: Séves) is a town and comune in the Province of Monza and Brianza, in the Region of Lombardy.

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Seveso disaster

The Seveso disaster was an industrial accident that occurred around 12:37 pm on July 10, 1976, in a small chemical manufacturing plant approximately north of Milan in the Lombardy region of Italy.

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SIX Swiss Exchange

SIX Swiss Exchange (formerly SWX Swiss Exchange), based in Zurich, is Switzerland's principal stock exchange (the other being Berne eXchange).

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South San Francisco, California

South San Francisco is a city in San Mateo County, California, United States, located on the San Francisco Peninsula in the San Francisco Bay Area.

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Spinal muscular atrophy

Spinal muscular atrophy (SMA) is a rare neuromuscular disorder characterised by loss of motor neurons and progressive muscle wasting, often leading to early death.

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Stanley Adams (whistleblower)

Stanley Adams (born c. 1927) is a former pharmaceutical company executive and corporate whistleblower, whose case was a cause célèbre in the 1970s.

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Subsidiary

A subsidiary, subsidiary company or daughter company"daughter company.

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Sulfadoxine/pyrimethamine

Sulfadoxine/pyrimethamine, sold under the brandname Fansidar, is a combination medication used to treat malaria.

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Swiss franc

The franc (sign: Fr. or SFr.; Franken, French and Romansh: franc, franco; code: CHF) is the currency and legal tender of Switzerland and Liechtenstein; it is also legal tender in the Italian exclave Campione d'Italia.

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Switzerland

Switzerland, officially the Swiss Confederation, is a sovereign state in Europe.

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Syntex

Laboratorios Syntex SA was a pharmaceutical company formed in Mexico City in 1944 by Russell Marker to manufacture therapeutic steroids from the Mexican yams called cabeza de negro (Dioscorea mexicana) and Barbasco (Dioscorea composita).

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The New York Times

The New York Times (sometimes abbreviated as The NYT or The Times) is an American newspaper based in New York City with worldwide influence and readership.

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The Observer

The Observer is a British newspaper published on Sundays.

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The Times

The Times is a British daily (Monday to Saturday) national newspaper based in London, England.

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Tocilizumab

Tocilizumab, also known as atlizumab, is an immunosuppressive drug, mainly for the treatment of rheumatoid arthritis (RA) and systemic juvenile idiopathic arthritis, a severe form of arthritis in children.

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Tranquilizer

A tranquilizer refers to a drug which is designed for the treatment of anxiety, fear, tension, agitation, and disturbances of the mind, specifically to reduce states of anxiety and tension.

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Trastuzumab

Trastuzumab, sold under the brand name Herceptin among others, is a monoclonal antibody used to treat breast cancer.

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Tretinoin

Tretinoin, also known as all-trans retinoic acid (ATRA), is medication used for the treatment of acne and acute promyelocytic leukemia.

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Trimethoprim/sulfamethoxazole

Trimethoprim/sulfamethoxazole (TMP/SMX), also known as co-trimoxazole among other names, is an antibiotic used to treat a variety of bacterial infections.

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Trophos

Trophos was a biopharmaceutical company specialising in the discovery and development of novel therapeutics to treat both orphan neurodegenerative diseases and more prevalent disorders.

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Tuberculosis

Tuberculosis (TB) is an infectious disease usually caused by the bacterium Mycobacterium tuberculosis (MTB).

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Valganciclovir

Valganciclovir, sold under the brandname Valcyte among others, is an antiviral medication used to treat cytomegalovirus (CMV) infection in those with HIV/AIDS or following organ transplant.

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Vemurafenib

Vemurafenib (INN, marketed as Zelboraf) is a B-Raf enzyme inhibitor developed by Plexxikon (now part of Daiichi-Sankyo) and Genentech for the treatment of late-stage melanoma.

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Ventana Medical Systems

Ventana Medical Systems, Inc. is a global leader in tissue diagnostics.

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Vismodegib

Vismodegib (trade name Erivedge) is a drug for the treatment of basal-cell carcinoma (BCC).

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Vitamin

A vitamin is an organic molecule (or related set of molecules) which is an essential micronutrient - that is, a substance which an organism needs in small quantities for the proper functioning of its metabolism - but cannot synthesize it (either at all, or in sufficient quantities), and therefore it must be obtained through the diet.

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Vitamin C

Vitamin C, also known as ascorbic acid and L-ascorbic acid, is a vitamin found in food and used as a dietary supplement.

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Warner Chilcott

Warner Chilcott (formerly Galen) was a company in the pharmaceutical industry based in Rockaway, New Jersey.

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454 Life Sciences

454 Life Sciences was a biotechnology company based in Branford, Connecticut that specialized in high-throughput DNA sequencing.

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References

[1] https://en.wikipedia.org/wiki/Hoffmann-La_Roche

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