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113 relations: Acetal, Agency for Healthcare Research and Quality, Alcohol (drug), Allergy, Allosteric modulator, Alpha-adrenergic agonist, American Family Physician, Amitriptyline, Amobarbital, Ancient Greek, Anesthesia, Antidepressant, Antipsychotic, Anxiolytic, Assisted suicide, Atypical antipsychotic, Barbiturate, Barbituric acid, Benzodiazepine, Biological half-life, Blood–brain barrier, Cancer, Cannabidiol, Cannabinoid, Carbamate, Central nervous system, Chloral hydrate, Chlorpromazine, Choosing Wisely, Clonidine, Cloroqualone, Clozapine, Cognitive behavioral therapy for insomnia, Depressant, Diazepam, Dimethoxymethane, Diphenhydramine, Diproqualone, Diurnality, Doxepin, Doxylamine, Drug overdose, Drug tolerance, Epilepsy, Eszopiclone, Etaqualone, GABAA receptor, Gabapentinoid, Guanfacine, H1 antagonist, ..., Imagabalin, Insomnia, JAMA (journal), Longitudinal study, Mebroqualone, Mechanism of action, Mecloqualone, Melatonin, Meta-analysis, Methaqualone, Mianserin, Mirtazapine, National Institute for Health and Care Excellence, Night terror, Nitrazepam, Nonbenzodiazepine, Norepinephrine reuptake inhibitor, Off-label use, Olanzapine, Orexin antagonist, Over-the-counter drug, Paraldehyde, Pentobarbital, Pharmacodynamics, Phenibut, Phenobarbital, Physical dependence, Pregabalin, Psychoactive drug, Psychological dependence, Quetiapine, Quinazolinone, Rebound effect, Risperidone, Secobarbital, Sedation, Sedative, Selective serotonin reuptake inhibitor, Serotonin antagonist and reuptake inhibitor, Serotonin–norepinephrine reuptake inhibitor, Sleep, Sleep hygiene, Sleep induction, Sleepwalking, Slow-wave sleep, Sodium thiopental, Substance abuse, Substance dependence, Sulfonmethane, Surgery, Suvorexant, Tetracyclic antidepressant, Tetrahydrocannabinol, Traffic collision, Trazodone, Tricyclic antidepressant, Trimipramine, Typical antipsychotic, Z-drug, Zaleplon, Zolpidem, Zopiclone, Zotepine. Expand index (63 more) »
Acetal
An acetal is a functional group with the following connectivity R2C(OR')2, where both R' groups are organic fragments.
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Agency for Healthcare Research and Quality
The Agency for Healthcare Research and Quality (AHRQ), located in Rockville, MD, a suburb of Washington, D.C., is one of 12 Agencies within the United States Department of Health and Human Services (HHS).
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Alcohol (drug)
Alcohol, also known by its chemical name ethanol, is a psychoactive substance or drug that is the active ingredient in alcoholic beverages such as beer, wine, and distilled spirits (hard liquor).
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Allergy
Allergies, also known as allergic diseases, are a number of conditions caused by hypersensitivity of the immune system to typically harmless substances in the environment.
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Allosteric modulator
In biochemistry and pharmacology, an allosteric modulator (allo- from the Greek meaning "other") is a substance which indirectly influences (modulates) the effects of a primary ligand that directly activates or deactivates the function of a target protein.
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Alpha-adrenergic agonist
Adrenergic alpha-agonists (or alpha-adrenergic agonists) are a class of sympathomimetic agents that selectively stimulates alpha adrenergic receptors.
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American Family Physician
American Family Physician is a biweekly peer-reviewed medical journal published by the American Academy of Family Physicians.
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Amitriptyline
Amitriptyline, sold under the brand name Elavil among others, is a medicine primarily used to treat a number of mental illnesses.
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Amobarbital
Amobarbital (formerly known as amylobarbitone or sodium amytal) is a drug that is a barbiturate derivative.
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Ancient Greek
The Ancient Greek language includes the forms of Greek used in ancient Greece and the ancient world from around the 9th century BC to the 6th century AD.
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Anesthesia
In the practice of medicine (especially surgery and dentistry), anesthesia or anaesthesia (from Greek "without sensation") is a state of temporary induced loss of sensation or awareness.
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Antidepressant
Antidepressants are drugs used for the treatment of major depressive disorder and other conditions, including dysthymia, anxiety disorders, obsessive–compulsive disorder, eating disorders, chronic pain, neuropathic pain and, in some cases, dysmenorrhoea, snoring, migraine, attention-deficit hyperactivity disorder (ADHD), addiction, dependence, and sleep disorders.
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Antipsychotic
Antipsychotics, also known as neuroleptics or major tranquilizers, are a class of medication primarily used to manage psychosis (including delusions, hallucinations, paranoia or disordered thought), principally in schizophrenia and bipolar disorder.
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Anxiolytic
An anxiolytic (also antipanic or antianxiety agent) is a medication or other intervention that inhibits anxiety.
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Assisted suicide
Assisted suicide is suicide committed with the aid of another person, sometimes a physician.
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Atypical antipsychotic
The atypical antipsychotics (AAP; also known as second generation antipsychotics (SGAs)) are a group of antipsychotic drugs (antipsychotic drugs in general are also known as major tranquilizers and neuroleptics, although the latter is usually reserved for the typical antipsychotics) used to treat psychiatric conditions.
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Barbiturate
A barbiturate is a drug that acts as a central nervous system depressant, and can therefore produce a wide spectrum of effects, from mild sedation to death.
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Barbituric acid
Barbituric acid or malonylurea or 6-hydroxyuracil is an organic compound based on a pyrimidine heterocyclic skeleton.
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Benzodiazepine
Benzodiazepines (BZD, BZs), sometimes called "benzos", are a class of psychoactive drugs whose core chemical structure is the fusion of a benzene ring and a diazepine ring.
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Biological half-life
The biological half-life of a biological substance is the time it takes for half to be removed by biological processes when the rate of removal is roughly exponential.
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Blood–brain barrier
The blood–brain barrier (BBB) is a highly selective semipermeable membrane barrier that separates the circulating blood from the brain and extracellular fluid in the central nervous system (CNS).
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Cancer
Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body.
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Cannabidiol
Cannabidiol (CBD) is a naturally occurring cannabinoid constituent of cannabis.
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Cannabinoid
A cannabinoid is one of a class of diverse chemical compounds that acts on cannabinoid receptors in cells that alter neurotransmitter release in the brain.
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Carbamate
A carbamate is an organic compound derived from carbamic acid (NH2COOH).
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Central nervous system
The central nervous system (CNS) is the part of the nervous system consisting of the brain and spinal cord.
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Chloral hydrate
Chloral hydrate is a geminal diol with the formula C2H3Cl3O2.
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Chlorpromazine
Chlorpromazine (CPZ), marketed under the trade names Thorazine and Largactil among others, is an antipsychotic medication.
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Choosing Wisely
Choosing Wisely is a United States-based health educational campaign, led by the American Board of Internal Medicine (ABIM).
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Clonidine
Clonidine (trade names Catapres, Kapvay, Nexiclon, Clophelin, and others) is a medication used to treat high blood pressure, attention deficit hyperactivity disorder, anxiety disorders, tic disorders, withdrawal (from either alcohol, opioids, or smoking), migraine, menopausal flushing, diarrhea, and certain pain conditions.
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Cloroqualone
Cloroqualone is a quinazolinone-class GABAergic and is an analogue of methaqualone developed in the 1980s and marketed mainly in France and some other European countries.
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Clozapine
Clozapine, sold under the brand name Clozaril among others, is an atypical antipsychotic medication.
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Cognitive behavioral therapy for insomnia
Cognitive behavioral therapy for insomnia (CBT-I) is a technique for treating insomnia without (or alongside) medications.
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Depressant
A depressant, or central depressant, is a drug that lowers neurotransmission levels, which is to depress or reduce arousal or stimulation, in various areas of the brain.
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Diazepam
Diazepam, first marketed as Valium, is a medicine of the benzodiazepine family that typically produces a calming effect.
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Dimethoxymethane
Dimethoxymethane, also called methylal, is a colorless flammable liquid with a low boiling point, low viscosity and excellent dissolving power.
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Diphenhydramine
Diphenhydramine is an antihistamine mainly used to treat allergies.
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Diproqualone
Diproqualone is a quinazolinone class GABAergic and is an analogue of methaqualone developed in the late 1950s by a team at Nogentaise de Produits Chimique.
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Diurnality
Diurnality is a form of plant or animal behavior characterized by activity during the day, with a period of sleeping, or other inactivity, at night.
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Doxepin
Doxepin is a tricyclic antidepressant (TCA) used as a pill to treat major depressive disorder, anxiety disorders, chronic hives, and for short-term help with trouble remaining asleep after going to bed (a form of insomnia).
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Doxylamine
Doxylamine is a first-generation antihistamine.
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Drug overdose
The term drug overdose (or simply overdose or OD) describes the ingestion or application of a drug or other substance in quantities greater than are recommended or generally practiced.
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Drug tolerance
Drug tolerance is a pharmacological concept describing subjects' reduced reaction to a drug following its repeated use.
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Epilepsy
Epilepsy is a group of neurological disorders characterized by epileptic seizures.
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Eszopiclone
Eszopiclone, marketed by Sunovion under the brand-name Lunesta, is a nonbenzodiazepine hypnotic agent used in the treatment of insomnia.
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Etaqualone
Etaqualone (Aolan, Athinazone, Ethinazone) is a quinazolinone-class GABAergic and is an analogue of methaqualone that was developed in the 1960s and marketed mainly in France and some other European countries.
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GABAA receptor
The GABAA receptor (GABAAR) is an ionotropic receptor and ligand-gated ion channel.
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Gabapentinoid
Gabapentinoids, also known as α2δ ligands, are a class of drugs that are derivatives of the inhibitory neurotransmitter γ-aminobutyric acid (GABA) (i.e., GABA analogues) which block α2δ subunit-containing voltage-dependent calcium channels (VDCCs).
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Guanfacine
Guanfacine (trade names Estulic, Tenex, and, in extended release form, Intuniv) is a sympatholytic drug used to treat hypertension and attention deficit hyperactivity disorder (ADHD).
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H1 antagonist
H1 antagonists, also called H1 blockers, are a class of medications that block the action of histamine at the H1 receptor, helping to relieve allergic reactions.
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Imagabalin
Imagabalin (INN, USAN; PD-332,334) is a drug which acts as a ligand for the α2δ subunit of the voltage-dependent calcium channel, with some selectivity for the α2δ1 subunit over α2δ2.
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Insomnia
Insomnia, also known as sleeplessness, is a sleep disorder where people have trouble sleeping.
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JAMA (journal)
JAMA: The Journal of the American Medical Association is a peer-reviewed medical journal published 48 times a year by the American Medical Association.
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Longitudinal study
A longitudinal study (or longitudinal survey, or panel study) is a research design that involves repeated observations of the same variables (e.g., people) over short or long periods of time (i.e., uses longitudinal data).
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Mebroqualone
Mebroqualone (MBQ) is a quinazolinone-class GABAergic and is an analogue of mecloqualone that has similar sedative and hypnotic properties to its parent compound, resulting from its agonist activity at the β subtype of the GABAa receptor.
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Mechanism of action
In pharmacology, the term mechanism of action (MOA) refers to the specific biochemical interaction through which a drug substance produces its pharmacological effect.
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Mecloqualone
Mecloqualone (Nubarene, Casfen) is a quinazolinone-class GABAergic and is an analogue of methaqualone that was first made in 1960 and marketed mainly in France and some other European countries.
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Melatonin
Melatonin, also known as N-acetyl-5-methoxy tryptamine, is a hormone that is produced by the pineal gland in animals and regulates sleep and wakefulness.
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Meta-analysis
A meta-analysis is a statistical analysis that combines the results of multiple scientific studies.
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Methaqualone
Methaqualone, sold under the brand name Quaalude (pronounced) and sometimes stylized "Quāālude" in the United States and Mandrax in the United Kingdom and South Africa, is a sedative and hypnotic medication.
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Mianserin
Mianserin, sold under the brand name Tolvon among others, is an atypical antidepressant which is used in the treatment of depression in Europe and elsewhere in the world.
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Mirtazapine
Mirtazapine, sold under the brand name Remeron among others, is an atypical antidepressant which is used primarily in the treatment of depression.
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National Institute for Health and Care Excellence
The National Institute for Health and Care Excellence (NICE) is an executive non-departmental public body of the Department of Health in the United Kingdom, which publishes guidelines in four areas.
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Night terror
Night terror, also known as sleep terror, is a sleep disorder, causing feelings of terror or dread, and typically occurs during the first hours of stage 3–4 non-rapid eye movement (NREM) sleep.
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Nitrazepam
Nitrazepam (brand names Alodorm and Mogadon, among others) is a hypnotic drug of the benzodiazepine class used for short-term relief from severe, disabling anxiety and insomnia.
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Nonbenzodiazepine
Nonbenzodiazepines (sometimes referred to colloquially as "Z-drugs") are a class of psychoactive drugs that are very benzodiazepine-like in nature.
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Norepinephrine reuptake inhibitor
A norepinephrine reuptake inhibitor (NRI, NERI) or adrenergic reuptake inhibitor (ARI), is a type of drug that acts as a reuptake inhibitor for the neurotransmitters norepinephrine (noradrenaline) and epinephrine (adrenaline) by blocking the action of the norepinephrine transporter (NET).
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Off-label use
Off-label use is the use of pharmaceutical drugs for an unapproved indication or in an unapproved age group, dosage, or route of administration.
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Olanzapine
Olanzapine (originally branded Zyprexa) is an antipsychotic medication used to treat schizophrenia and bipolar disorder.
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Orexin antagonist
An orexin receptor antagonist is a drug that inhibits the effect of orexin by acting as a receptor antagonist of the orexin receptor.
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Over-the-counter drug
Over-the-counter (OTC) drugs are medicines sold directly to a consumer without a prescription from a healthcare professional, as opposed to prescription drugs, which may be sold only to consumers possessing a valid prescription.
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Paraldehyde
Paraldehyde is the cyclic trimer of acetaldehyde molecules.
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Pentobarbital
Pentobarbital (INN, AAN, BAN, USAN) or pentobarbitone (former AAN and BAN) is a short-acting barbiturate.
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Pharmacodynamics
Pharmacodynamics is the study of the biochemical and physiologic effects of drugs (especially pharmaceutical drugs).
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Phenibut
Phenibut, sold under the brand names Anvifen, Fenibut, and Noofen among others, is a central nervous system depressant with anxiolytic and sedative effects which is used in the treatment of anxiety, insomnia, and for a variety of other indications.
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Phenobarbital
Phenobarbital, also known as phenobarbitone or phenobarb, is a medication recommended by the World Health Organization for the treatment of certain types of epilepsy in developing countries.
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Physical dependence
Physical dependence is a physical condition caused by chronic use of a tolerance forming drug, in which abrupt or gradual drug withdrawal causes unpleasant physical symptoms.
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Pregabalin
Pregabalin, marketed under the brand name Lyrica among others, is a medication used to treat epilepsy, neuropathic pain, fibromyalgia, and generalized anxiety disorder.
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Psychoactive drug
A psychoactive drug, psychopharmaceutical, or psychotropic is a chemical substance that changes brain function and results in alterations in perception, mood, consciousness, cognition, or behavior.
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Psychological dependence
Psychological dependence is a form of dependence that involves emotional–motivational withdrawal symptoms (e.g., a state of unease or dissatisfaction, a reduced capacity to experience pleasure, or anxiety) upon cessation of drug use or exposure to a stimulus.
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Quetiapine
Quetiapine, marketed as Seroquel among other names, is an atypical antipsychotic used for the treatment of schizophrenia, bipolar disorder, and major depressive disorder.
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Quinazolinone
Quinazolinone is a heterocyclic chemical compound, a quinazoline with a keto group.
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Rebound effect
The rebound effect, or rebound phenomenon, is the emergence or re-emergence of symptoms that were either absent or controlled while taking a medication, but appear when that same medication is discontinued, or reduced in dosage.
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Risperidone
Risperidone, sold under the trade name Risperdal among others, is an antipsychotic medication.
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Secobarbital
Secobarbital sodium (marketed by Eli Lilly and Company, and subsequently by other companies as described below, under the brand name Seconal) is a barbiturate derivative drug that was patented in 1934 in the United States.
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Sedation
Sedation is the reduction of irritability or agitation by administration of sedative drugs, generally to facilitate a medical procedure or diagnostic procedure.
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Sedative
A sedative or tranquilliser is a substance that induces sedation by reducing irritability or excitement.
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Selective serotonin reuptake inhibitor
Selective serotonin reuptake inhibitors (SSRIs) are a class of drugs that are typically used as antidepressants in the treatment of major depressive disorder and anxiety disorders.
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Serotonin antagonist and reuptake inhibitor
Serotonin antagonist and reuptake inhibitors (SARIs) are a class of drugs used mainly as antidepressants, but also as anxiolytics and hypnotics.
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Serotonin–norepinephrine reuptake inhibitor
Serotonin–norepinephrine reuptake inhibitors (SNRIs) are a class of antidepressant drugs that treat major depressive disorder (MDD) and can also treat anxiety disorders, obsessive-compulsive disorder (OCD), attention-deficit hyperactivity disorder (ADHD), chronic neuropathic pain, fibromyalgia syndrome (FMS), and menopausal symptoms.
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Sleep
Sleep is a naturally recurring state of mind and body, characterized by altered consciousness, relatively inhibited sensory activity, inhibition of nearly all voluntary muscles, and reduced interactions with surroundings.
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Sleep hygiene
Sleep hygiene is the recommended behavioral and environmental practice that is intended to promote better quality sleep.
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Sleep induction
Sleep induction is the deliberate effort to bring on sleep by various techniques or medicinal means, is practiced to lengthen periods of sleep, increase the effectiveness of sleep, and to reduce or prevent insomnia.
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Sleepwalking
Sleepwalking, also known as somnambulism or noctambulism, is a phenomenon of combined sleep and wakefulness.
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Slow-wave sleep
Slow-wave sleep (SWS), often referred to as deep sleep, consists of stage three (combined stages 3 and 4) of non-rapid eye movement sleep.
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Sodium thiopental
Sodium thiopental, also known as Sodium Pentothal (a trademark of Abbott Laboratories, not to be confused with pentobarbital), thiopental, thiopentone, or Trapanal (also a trademark), is a rapid-onset short-acting barbiturate general anesthetic that is an analogue of thiobarbital.
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Substance abuse
Substance abuse, also known as drug abuse, is a patterned use of a drug in which the user consumes the substance in amounts or with methods which are harmful to themselves or others, and is a form of substance-related disorder.
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Substance dependence
Substance dependence also known as drug dependence is an adaptive state that develops from repeated drug administration, and which results in withdrawal upon cessation of drug use.
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Sulfonmethane
Sulfonmethane (Sulfonomethane, Sulfonal, Acetone diethyl sulfone) is a chemical compound first synthesized by Eugen Baumann in 1888 and introduced as a hypnotic drug by Alfred Kast later on, but now superseded by newer and safer sedatives.
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Surgery
Surgery (from the χειρουργική cheirourgikē (composed of χείρ, "hand", and ἔργον, "work"), via chirurgiae, meaning "hand work") is a medical specialty that uses operative manual and instrumental techniques on a patient to investigate or treat a pathological condition such as a disease or injury, to help improve bodily function or appearance or to repair unwanted ruptured areas.
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Suvorexant
Suvorexant, sold under the trade name Belsomra, is a medication for the treatment of insomnia.
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Tetracyclic antidepressant
Tetracyclic antidepressants (TeCAs) are a class of antidepressants that were first introduced starting in the 1970s.
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Tetrahydrocannabinol
Tetrahydrocannabinol (THC) is one of at least 113 cannabinoids identified in cannabis.
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Traffic collision
A traffic collision, also called a motor vehicle collision (MVC) among other terms, occurs when a vehicle collides with another vehicle, pedestrian, animal, road debris, or other stationary obstruction, such as a tree, pole or building.
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Trazodone
Trazodone, sold under many brand names worldwide, Page accessed Feb 10, 2016 is an antidepressant medication.
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Tricyclic antidepressant
Tricyclic antidepressants (TCAs) are a class of medications that are used primarily as antidepressants.
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Trimipramine
Trimipramine, sold under the brand name Surmontil among others, is a tricyclic antidepressant (TCA) which is used to treat depression.
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Typical antipsychotic
Typical antipsychotics are a class of antipsychotic drugs first developed in the 1950s and used to treat psychosis (in particular, schizophrenia).
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Z-drug
Z-drugs are a group of nonbenzodiazepine drugs with effects similar to benzodiazepines, which are used in the treatment of trouble sleeping, and most of whose names start with the letter "Z".
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Zaleplon
Zaleplon (marketed under the brand names Sonata, Starnoc, and Andante) is a sedative-hypnotic, almost entirely used for the management/treatment of insomnia.
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Zolpidem
Zolpidem, sold under the brand name Ambien, among others, is a sedative primarily used for the treatment of trouble sleeping.
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Zopiclone
--> Zopiclone (brand names Imovane, Zimovane, Dopareel) is a nonbenzodiazepine hypnotic agent used in the treatment of insomnia.
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Zotepine
Zotepine (brand names: Losizopilon (JP), Lodopin (ID, JP), Setous (JP), Zoleptil (CZ, PT, TR, UK†); where † indicates a formulation that has been discontinued) is an atypical antipsychotic drug indicated for acute and chronic schizophrenia.
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Hypnotic drug, Hypnotic drugs, Hypnotic-sedative, Hypnotica (medicine), Hypnotics, Sleep pill, Sleep pills, Sleeping Pills, Sleeping pill, Sleeping pills, Sleeping tablet, Sleeping tablets, Somnorific, Soporific.
References
[1] https://en.wikipedia.org/wiki/Hypnotic
