Logo
Unionpedia
Communication
Get it on Google Play
New! Download Unionpedia on your Android™ device!
Free
Faster access than browser!
 

Octreotide

Index Octreotide

Octreotide (trade name Sandostatin, among others) is an octapeptide that mimics natural somatostatin pharmacologically, though it is a more potent inhibitor of growth hormone, glucagon, and insulin than the natural hormone. [1]

94 relations: Acetate, Acromegaly, Acute lymphoblastic leukemia, Adipogenesis, Analgesic, Anaphylaxis, Anterior pituitary, Anti-diabetic medication, Antiparkinson medication, Arcuate nucleus, Beck Depression Inventory, Bilirubin, Bioavailability, Biological half-life, Bleeding, Body mass index, Bradycardia, Bromocriptine, Carcinoid syndrome, Caucasian race, Cholecystokinin, Chronic pancreatitis, Chylothorax, Ciclosporin, Cirrhosis, Clinical trial, Cluster headache, Diabetes mellitus, Diarrhea, Dizziness, Electrical conduction system of the heart, Erectile dysfunction, Esophageal varices, Flushing (physiology), Gallbladder, Gallstone, Gastrin, Gastrointestinal tract, Gigantism, Glucagon, Glucose tolerance test, Growth hormone, Hair loss, Hepatitis, Hepatorenal syndrome, Hyperglycemia, Hypoglycemia, Hypotension, Hypothalamus, Hypothyroidism, ..., Idiopathic intracranial hypertension, Indium-111, Insulin, Intramuscular injection, Intravenous therapy, Isotopes of carbon, Isotopes of gallium, Isotopes of lutetium, Itch, Μ-opioid receptor, Lateral hypothalamus, Liver, Midodrine, Nesidioblastosis, Nuclear medicine, Obesity, Octreotate, Off-label use, Pamoic acid, Pancreas, Pancreatic polypeptide, Pancreatitis, Partial agonist, Peptide, Peptide receptor radionuclide therapy, Placebo, Portal hypertension, Positron emission tomography, Posterior cranial fossa, QT interval, Quality of life, Risk–benefit ratio, Secretin, Shortness of breath, Somatostatin, Subcutaneous injection, Sulfonylurea, Thyroid-stimulating hormone, Vagus nerve, Vasoactive intestinal peptide, Vasoconstriction, Ventromedial nucleus of the hypothalamus, VIPoma, Yttrium-90. Expand index (44 more) »

Acetate

An acetate is a salt formed by the combination of acetic acid with an alkaline, earthy, metallic or nonmetallic and other base.

New!!: Octreotide and Acetate · See more »

Acromegaly

Acromegaly is a disorder that results from excess growth hormone (GH) after the growth plates have closed.

New!!: Octreotide and Acromegaly · See more »

Acute lymphoblastic leukemia

Acute lymphoblastic leukemia (ALL) is a cancer of the lymphoid line of blood cells characterized by the development of large numbers of immature lymphocytes.

New!!: Octreotide and Acute lymphoblastic leukemia · See more »

Adipogenesis

Adipogenesis is the process of cell differentiation by which pre-adipocytes become adipocytes.

New!!: Octreotide and Adipogenesis · See more »

Analgesic

An analgesic or painkiller is any member of the group of drugs used to achieve analgesia, relief from pain.

New!!: Octreotide and Analgesic · See more »

Anaphylaxis

Anaphylaxis is a serious allergic reaction that is rapid in onset and may cause death.

New!!: Octreotide and Anaphylaxis · See more »

Anterior pituitary

A major organ of the endocrine system, the anterior pituitary (also called the adenohypophysis or pars anterior), is the glandular, anterior lobe that together with the posterior lobe (posterior pituitary, or the neurohypophysis) makes up the pituitary gland (hypophysis).

New!!: Octreotide and Anterior pituitary · See more »

Anti-diabetic medication

Drugs used in diabetes treat diabetes mellitus by lowering glucose levels in the blood.

New!!: Octreotide and Anti-diabetic medication · See more »

Antiparkinson medication

An antiparkinson medication is a type of drug which is intended to treat and relieve the symptoms of Parkinson's disease.

New!!: Octreotide and Antiparkinson medication · See more »

Arcuate nucleus

The arcuate nucleus of the hypothalamus (also known as ARH, ARC, or infundibular nucleus) is an aggregation of neurons in the mediobasal hypothalamus, adjacent to the third ventricle and the median eminence.

New!!: Octreotide and Arcuate nucleus · See more »

Beck Depression Inventory

The Beck Depression Inventory (BDI, BDI-1A, BDI-II), created by Aaron T. Beck, is a 21-question multiple-choice self-report inventory, one of the most widely used psychometric tests for measuring the severity of depression.

New!!: Octreotide and Beck Depression Inventory · See more »

Bilirubin

Bilirubin is a yellow compound that occurs in the normal catabolic pathway that breaks down heme in vertebrates.

New!!: Octreotide and Bilirubin · See more »

Bioavailability

In pharmacology, bioavailability (BA or F) is a subcategory of absorption and is the fraction of an administered dose of unchanged drug that reaches the systemic circulation, one of the principal pharmacokinetic properties of drugs.

New!!: Octreotide and Bioavailability · See more »

Biological half-life

The biological half-life of a biological substance is the time it takes for half to be removed by biological processes when the rate of removal is roughly exponential.

New!!: Octreotide and Biological half-life · See more »

Bleeding

Bleeding, also known as hemorrhaging or haemorrhaging, is blood escaping from the circulatory system.

New!!: Octreotide and Bleeding · See more »

Body mass index

The body mass index (BMI) or Quetelet index is a value derived from the mass (weight) and height of an individual.

New!!: Octreotide and Body mass index · See more »

Bradycardia

Bradycardia is a condition wherein an individual has a very slow heart rate, typically defined as a resting heart rate of under 60 beats per minute (BPM) in adults.

New!!: Octreotide and Bradycardia · See more »

Bromocriptine

Bromocriptine (originally marketed as Parlodel, subsequently under many names) is an ergoline derivative, is a dopamine agonist that is used in the treatment of pituitary tumors, Parkinson's disease (PD), hyperprolactinaemia, neuroleptic malignant syndrome, and type 2 diabetes.

New!!: Octreotide and Bromocriptine · See more »

Carcinoid syndrome

Carcinoid syndrome is a paraneoplastic syndrome comprising the signs and symptoms that occur secondary to carcinoid tumors.

New!!: Octreotide and Carcinoid syndrome · See more »

Caucasian race

The Caucasian race (also Caucasoid or Europid) is a grouping of human beings historically regarded as a biological taxon, which, depending on which of the historical race classifications used, have usually included some or all of the ancient and modern populations of Europe, the Caucasus, Asia Minor, North Africa, the Horn of Africa, Western Asia, Central Asia and South Asia.

New!!: Octreotide and Caucasian race · See more »

Cholecystokinin

Cholecystokinin (CCK or CCK-PZ; from Greek chole, "bile"; cysto, "sac"; kinin, "move"; hence, move the bile-sac (gallbladder)) is a peptide hormone of the gastrointestinal system responsible for stimulating the digestion of fat and protein.

New!!: Octreotide and Cholecystokinin · See more »

Chronic pancreatitis

Chronic pancreatitis is a long-standing inflammation of the pancreas that alters the organ's normal structure and functions.

New!!: Octreotide and Chronic pancreatitis · See more »

Chylothorax

A chylothorax (or chyle leak) is a type of pleural effusion.

New!!: Octreotide and Chylothorax · See more »

Ciclosporin

Ciclosporin, also spelled cyclosporine and cyclosporin, is an immunosuppressant medication and natural product.

New!!: Octreotide and Ciclosporin · See more »

Cirrhosis

Cirrhosis is a condition in which the liver does not function properly due to long-term damage.

New!!: Octreotide and Cirrhosis · See more »

Clinical trial

Clinical trials are experiments or observations done in clinical research.

New!!: Octreotide and Clinical trial · See more »

Cluster headache

Cluster headache (CH) is a neurological disorder characterized by recurrent, severe headaches on one side of the head, typically around the eye.

New!!: Octreotide and Cluster headache · See more »

Diabetes mellitus

Diabetes mellitus (DM), commonly referred to as diabetes, is a group of metabolic disorders in which there are high blood sugar levels over a prolonged period.

New!!: Octreotide and Diabetes mellitus · See more »

Diarrhea

Diarrhea, also spelled diarrhoea, is the condition of having at least three loose or liquid bowel movements each day.

New!!: Octreotide and Diarrhea · See more »

Dizziness

Dizziness is an impairment in spatial perception and stability.

New!!: Octreotide and Dizziness · See more »

Electrical conduction system of the heart

The electrical conduction system of the heart transmits signals generated usually by the sinoatrial node to cause contraction of the heart muscle.

New!!: Octreotide and Electrical conduction system of the heart · See more »

Erectile dysfunction

Erectile dysfunction (ED), also known as impotence, is a type of sexual dysfunction characterized by the inability to develop or maintain an erection of the penis during sexual activity.

New!!: Octreotide and Erectile dysfunction · See more »

Esophageal varices

Esophageal varices (sometimes spelled oesophageal varices) are extremely dilated sub-mucosal veins in the lower third of the esophagus.

New!!: Octreotide and Esophageal varices · See more »

Flushing (physiology)

For a person to flush is to become markedly red in the face and often other areas of the skin, from various physiological conditions.

New!!: Octreotide and Flushing (physiology) · See more »

Gallbladder

In vertebrates, the gallbladder is a small hollow organ where bile is stored and concentrated before it is released into the small intestine.

New!!: Octreotide and Gallbladder · See more »

Gallstone

A gallstone is a stone formed within the gallbladder out of bile components. The term cholelithiasis may refer to the presence of gallstones or to the diseases caused by gallstones. Most people with gallstones (about 80%) never have symptoms. When a gallstone blocks the bile duct, a crampy pain in the right upper part of the abdomen, known as biliary colic (gallbladder attack) can result. This happens in 1–4% of those with gallstones each year. Complications of gallstones may include inflammation of the gallbladder (cholecystitis), inflammation of the pancreas (pancreatitis), jaundice, and infection of a bile duct (cholangitis). Symptoms of these complications may include pain of more than five hours duration, fever, yellowish skin, vomiting, dark urine, and pale stools. Risk factors for gallstones include birth control pills, pregnancy, a family history of gallstones, obesity, diabetes, liver disease, or rapid weight loss. The bile components that form gallstones include cholesterol, bile salts, and bilirubin. Gallstones formed mainly from cholesterol are termed cholesterol stones, and those mainly from bilirubin are termed pigment stones. Gallstones may be suspected based on symptoms. Diagnosis is then typically confirmed by ultrasound. Complications may be detected on blood tests. The risk of gallstones may be decreased by maintaining a healthy weight through sufficient exercise and eating a healthy diet. If there are no symptoms, treatment is usually not needed. In those who are having gallbladder attacks, surgery to remove the gallbladder is typically recommended. This can be carried out either through several small incisions or through a single larger incision, usually under general anesthesia. In rare cases when surgery is not possible medication may be used to try to dissolve the stones or lithotripsy to break down the stones. In developed countries, 10–15% of adults have gallstones. Rates in many parts of Africa, however, are as low as 3%. Gallbladder and biliary related diseases occurred in about 104 million people (1.6%) in 2013 and they resulted in 106,000 deaths. Women more commonly have stones than men and they occur more commonly after the age of 40. Certain ethnic groups have gallstones more often than others. For example, 48% of Native Americans have gallstones. Once the gallbladder is removed, outcomes are generally good.

New!!: Octreotide and Gallstone · See more »

Gastrin

Gastrin is a peptide hormone that stimulates secretion of gastric acid (HCl) by the parietal cells of the stomach and aids in gastric motility.

New!!: Octreotide and Gastrin · See more »

Gastrointestinal tract

The gastrointestinal tract (digestive tract, digestional tract, GI tract, GIT, gut, or alimentary canal) is an organ system within humans and other animals which takes in food, digests it to extract and absorb energy and nutrients, and expels the remaining waste as feces.

New!!: Octreotide and Gastrointestinal tract · See more »

Gigantism

Gigantism, also known as giantism (from Greek γίγας gigas, "giant", plural γίγαντες gigantes), is a condition characterized by excessive growth and height significantly above average.

New!!: Octreotide and Gigantism · See more »

Glucagon

Glucagon is a peptide hormone, produced by alpha cells of the pancreas.

New!!: Octreotide and Glucagon · See more »

Glucose tolerance test

The glucose tolerance test is a medical test in which glucose is given and blood samples taken afterward to determine how quickly it is cleared from the blood.

New!!: Octreotide and Glucose tolerance test · See more »

Growth hormone

Growth hormone (GH), also known as somatotropin (or as human growth hormone in its human form), is a peptide hormone that stimulates growth, cell reproduction, and cell regeneration in humans and other animals.

New!!: Octreotide and Growth hormone · See more »

Hair loss

Hair loss, also known as alopecia or baldness, refers to a loss of hair from part of the head or body.

New!!: Octreotide and Hair loss · See more »

Hepatitis

Hepatitis is inflammation of the liver tissue.

New!!: Octreotide and Hepatitis · See more »

Hepatorenal syndrome

Hepatorenal syndrome (often abbreviated HRS) is a life-threatening medical condition that consists of rapid deterioration in kidney function in individuals with cirrhosis or fulminant liver failure.

New!!: Octreotide and Hepatorenal syndrome · See more »

Hyperglycemia

Hyperglycemia, or high blood sugar (also spelled hyperglycaemia or hyperglycæmia) is a condition in which an excessive amount of glucose circulates in the blood plasma.

New!!: Octreotide and Hyperglycemia · See more »

Hypoglycemia

Hypoglycemia, also known as low blood sugar, is when blood sugar decreases to below normal levels.

New!!: Octreotide and Hypoglycemia · See more »

Hypotension

Hypotension is low blood pressure, especially in the arteries of the systemic circulation.

New!!: Octreotide and Hypotension · See more »

Hypothalamus

The hypothalamus(from Greek ὑπό, "under" and θάλαμος, thalamus) is a portion of the brain that contains a number of small nuclei with a variety of functions.

New!!: Octreotide and Hypothalamus · See more »

Hypothyroidism

Hypothyroidism, also called underactive thyroid or low thyroid, is a disorder of the endocrine system in which the thyroid gland does not produce enough thyroid hormone.

New!!: Octreotide and Hypothyroidism · See more »

Idiopathic intracranial hypertension

Idiopathic intracranial hypertension (IIH) is a condition characterized by increased intracranial pressure (pressure around the brain) without a detectable cause.

New!!: Octreotide and Idiopathic intracranial hypertension · See more »

Indium-111

Indium-111 is an isotope of indium with a radioactive half-life of 2.80 days, making it useful as a radioactive tracer.

New!!: Octreotide and Indium-111 · See more »

Insulin

Insulin (from Latin insula, island) is a peptide hormone produced by beta cells of the pancreatic islets; it is considered to be the main anabolic hormone of the body.

New!!: Octreotide and Insulin · See more »

Intramuscular injection

Intramuscular (also IM or im) injection is the injection of a substance directly into muscle.

New!!: Octreotide and Intramuscular injection · See more »

Intravenous therapy

Intravenous therapy (IV) is a therapy that delivers liquid substances directly into a vein (intra- + ven- + -ous).

New!!: Octreotide and Intravenous therapy · See more »

Isotopes of carbon

Carbon (6C) has 15 known isotopes, from 8C to 22C, of which 12C and 13C are stable.

New!!: Octreotide and Isotopes of carbon · See more »

Isotopes of gallium

Natural gallium (31Ga) consists of a mixture of two stable isotopes: gallium-69 and gallium-71.

New!!: Octreotide and Isotopes of gallium · See more »

Isotopes of lutetium

Naturally occurring lutetium (71Lu) is composed of 1 stable isotope 175Lu (97.41% natural abundance) and one long-lived radioisotope, 176Lu with a half-life of 3.78 × 1010 years (2.59% natural abundance).

New!!: Octreotide and Isotopes of lutetium · See more »

Itch

Itch (also known as pruritus) is a sensation that causes the desire or reflex to scratch.

New!!: Octreotide and Itch · See more »

Μ-opioid receptor

The μ-opioid receptors (MOR) are a class of opioid receptors with a high affinity for enkephalins and beta-endorphin, but a low affinity for dynorphins.

New!!: Octreotide and Μ-opioid receptor · See more »

Lateral hypothalamus

The lateral hypothalamus, also called the lateral hypothalamic area, contains the primary orexinergic nucleus within the hypothalamus that widely projects throughout the nervous system; this system of neurons mediates an array of cognitive and physical processes, such as promoting feeding behavior and arousal, reducing pain perception, and regulating body temperature, digestive functions, and blood pressure, among many others.

New!!: Octreotide and Lateral hypothalamus · See more »

Liver

The liver, an organ only found in vertebrates, detoxifies various metabolites, synthesizes proteins, and produces biochemicals necessary for digestion.

New!!: Octreotide and Liver · See more »

Midodrine

Midodrine (brand names Amatine, ProAmatine, Gutron, Bramox) is a vasopressor/antihypotensive agent.

New!!: Octreotide and Midodrine · See more »

Nesidioblastosis

Nesidioblastosis is a controversial medical term for hyperinsulinemic hypoglycemia attributed to excessive function of pancreatic beta cells with an abnormal microscopic appearance.

New!!: Octreotide and Nesidioblastosis · See more »

Nuclear medicine

Nuclear medicine is a medical specialty involving the application of radioactive substances in the diagnosis and treatment of disease.

New!!: Octreotide and Nuclear medicine · See more »

Obesity

Obesity is a medical condition in which excess body fat has accumulated to the extent that it may have a negative effect on health.

New!!: Octreotide and Obesity · See more »

Octreotate

Octreotate or octreotide acid is a somatostatin analogue that is closely related to octreotide.

New!!: Octreotide and Octreotate · See more »

Off-label use

Off-label use is the use of pharmaceutical drugs for an unapproved indication or in an unapproved age group, dosage, or route of administration.

New!!: Octreotide and Off-label use · See more »

Pamoic acid

Pamoic acid, also called embonic acid, is a naphthoic acid derivative.

New!!: Octreotide and Pamoic acid · See more »

Pancreas

The pancreas is a glandular organ in the digestive system and endocrine system of vertebrates.

New!!: Octreotide and Pancreas · See more »

Pancreatic polypeptide

Pancreatic polypeptide (PP) is a polypeptide secreted by PP cells in the endocrine pancreas predominantly in the head of the pancreas.

New!!: Octreotide and Pancreatic polypeptide · See more »

Pancreatitis

Pancreatitis is inflammation of the pancreas.

New!!: Octreotide and Pancreatitis · See more »

Partial agonist

In pharmacology, partial agonists are drugs that bind to and activate a given receptor, but have only partial efficacy at the receptor relative to a full agonist.

New!!: Octreotide and Partial agonist · See more »

Peptide

Peptides (from Gr.: πεπτός, peptós "digested"; derived from πέσσειν, péssein "to digest") are short chains of amino acid monomers linked by peptide (amide) bonds.

New!!: Octreotide and Peptide · See more »

Peptide receptor radionuclide therapy

Peptide receptor radionuclide therapy (PRRT) is a type of unsealed source radiotherapy, using a radiopharmaceutical which targets peptide receptors to deliver localised treatment, typically for neuroendocrine tumours (NETs).

New!!: Octreotide and Peptide receptor radionuclide therapy · See more »

Placebo

A placebo is a substance or treatment of no intended therapeutic value.

New!!: Octreotide and Placebo · See more »

Portal hypertension

Portal hypertension is hypertension (high blood pressure) in the hepatic portal system – made up of the portal vein and its branches, that drain from most of the intestine to the liver.

New!!: Octreotide and Portal hypertension · See more »

Positron emission tomography

Positron-emission tomography (PET) is a nuclear medicine functional imaging technique that is used to observe metabolic processes in the body as an aid to the diagnosis of disease.

New!!: Octreotide and Positron emission tomography · See more »

Posterior cranial fossa

The posterior cranial fossa is part of the cranial cavity, located between the foramen magnum and tentorium cerebelli.

New!!: Octreotide and Posterior cranial fossa · See more »

QT interval

In cardiology, the QT interval is a measure of the time between the start of the Q wave and the end of the T wave in the heart's electrical cycle.

New!!: Octreotide and QT interval · See more »

Quality of life

Quality of life (QOL) is the general well-being of individuals and societies, outlining negative and positive features of life.

New!!: Octreotide and Quality of life · See more »

Risk–benefit ratio

A risk–benefit ratio is the ratio of the risk of an action to its potential benefits.

New!!: Octreotide and Risk–benefit ratio · See more »

Secretin

Secretin is a hormone that regulates water homeostasis throughout the body and influences the environment of the duodenum by regulating secretions in the stomach, pancreas, and liver.

New!!: Octreotide and Secretin · See more »

Shortness of breath

Shortness of breath, also known as dyspnea, is the feeling that one cannot breathe well enough.

New!!: Octreotide and Shortness of breath · See more »

Somatostatin

Somatostatin, also known as growth hormone-inhibiting hormone (GHIH) or by several other names, is a peptide hormone that regulates the endocrine system and affects neurotransmission and cell proliferation via interaction with G protein-coupled somatostatin receptors and inhibition of the release of numerous secondary hormones.

New!!: Octreotide and Somatostatin · See more »

Subcutaneous injection

A subcutaneous injection is administered as a bolus into the subcutis, the layer of skin directly below the dermis and epidermis, collectively referred to as the cutis.

New!!: Octreotide and Subcutaneous injection · See more »

Sulfonylurea

Sulfonylureas (UK: sulphonylurea) are a class of organic compounds used in medicine and agriculture.

New!!: Octreotide and Sulfonylurea · See more »

Thyroid-stimulating hormone

Thyroid-stimulating hormone (also known as thyrotropin, thyrotropic hormone, TSH, or hTSH for human TSH) is a pituitary hormone that stimulates the thyroid gland to produce thyroxine (T4), and then triiodothyronine (T3) which stimulates the metabolism of almost every tissue in the body.

New!!: Octreotide and Thyroid-stimulating hormone · See more »

Vagus nerve

The vagus nerve, historically cited as the pneumogastric nerve, is the tenth cranial nerve or CN X, and interfaces with parasympathetic control of the heart, lungs, and digestive tract.

New!!: Octreotide and Vagus nerve · See more »

Vasoactive intestinal peptide

Vasoactive intestinal peptide, also known as vasoactive intestinal polypeptide or VIP, is a peptide hormone that is vasoactive in the intestine.

New!!: Octreotide and Vasoactive intestinal peptide · See more »

Vasoconstriction

Vasoconstriction is the narrowing of the blood vessels resulting from contraction of the muscular wall of the vessels, in particular the large arteries and small arterioles.

New!!: Octreotide and Vasoconstriction · See more »

Ventromedial nucleus of the hypothalamus

The ventromedial nucleus of the hypothalamus (VMN, also sometimes referred to as the ventromedial hypothalamus, VMH) is a nucleus of the hypothalamus.

New!!: Octreotide and Ventromedial nucleus of the hypothalamus · See more »

VIPoma

A VIPoma (also known as Verner–Morrison syndrome, after the physicians who first described it) is a rare (1 per 10,000,000 per year) endocrine tumor, usually (about 90%) originating from non-β islet cell of the pancreas, that produce vasoactive intestinal peptide (VIP).

New!!: Octreotide and VIPoma · See more »

Yttrium-90

Yttrium-90,, is a medically significant isotope of yttrium.

New!!: Octreotide and Yttrium-90 · See more »

Redirects here:

ATC code H01CB02, ATCvet code QH01CB02, Atrigel, C49H66N10O10S2, Longastatin, Octeotide, Octeotride, Octreo, Octreotide acetate, Sandostatin, Sandostatin LAR.

References

[1] https://en.wikipedia.org/wiki/Octreotide

OutgoingIncoming
Hey! We are on Facebook now! »