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22 relations: Acid hydrolase, Asparagine, Endosome, Enzyme replacement therapy, Fructose 6-phosphate, Glycosylation, Golgi apparatus, I-cell disease, Immune system, Insulin-like growth factor 2 receptor, Lectin, Lysosomal storage disease, Lysosome, Mannose, Mannose 1-phosphate, Mannose 6-phosphate receptor, Mannose phosphate isomerase, Moiety (chemistry), N-Acetylglucosamine, N-acetylglucosamine-1-phosphate transferase, Protein precursor, Uridine diphosphate.
Acid hydrolase
An acid hydrolase (lysosomal acid lipase) is an enzyme that works best at acidic pHs.
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Asparagine
Asparagine (symbol Asn or N), is an α-amino acid that is used in the biosynthesis of proteins.
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Endosome
In cell biology, an endosome is a membrane-bound compartment inside eukaryotic cells.
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Enzyme replacement therapy
Enzyme replacement therapy (ERT) is a medical treatment which replaces an enzyme that is deficient or absent in the body.
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Fructose 6-phosphate
Fructose 6-phosphate (sometimes called the Neuberg ester) is a derivative of fructose, which has been phosphorylated at the 6-hydroxy group.
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Glycosylation
Glycosylation (see also chemical glycosylation) is the reaction in which a carbohydrate, i.e. a glycosyl donor, is attached to a hydroxyl or other functional group of another molecule (a glycosyl acceptor).
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Golgi apparatus
The Golgi apparatus, also known as the Golgi complex, Golgi body, or simply the Golgi, is an organelle found in most eukaryotic cells.
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I-cell disease
Inclusion-cell (I-cell) disease, also referred to as mucolipidosis II (ML II), is part of the lysosomal storage disease family and results from a defective phosphotransferase (an enzyme of the Golgi apparatus).
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Immune system
The immune system is a host defense system comprising many biological structures and processes within an organism that protects against disease.
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Insulin-like growth factor 2 receptor
Insulin-like growth factor 2 receptor (IGF2R), also called the cation-independent mannose-6-phosphate receptor (CI-MPR) is a protein that in humans is encoded by the IGF2R gene.
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Lectin
Lectins are carbohydrate-binding proteins, macromolecules that are highly specific for sugar moieties of other molecules.
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Lysosomal storage disease
Lysosomal storage diseases (LSDs) are a group of about 50 rare inherited metabolic disorders that result from defects in lysosomal function.
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Lysosome
A lysosome is a membrane-bound organelle found in nearly all animal cells.
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Mannose
Mannose, packaged as the nutritional supplement "d-mannose", is a sugar monomer of the aldohexose series of carbohydrates.
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Mannose 1-phosphate
Mannose 1-phosphate is a molecule involved in glycosylation.
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Mannose 6-phosphate receptor
The mannose 6-phosphate receptors (MPRs) are transmembrane glycoproteins that target enzymes to lysosomes in vertebrates.
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Mannose phosphate isomerase
Mannose-6 phosphate isomerase (MPI), alternately phosphomannose isomerase (PMI) is an enzyme which facilitates the interconversion of fructose 6-phosphate (F6P) and mannose-6-phosphate (M6P).
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Moiety (chemistry)
In organic chemistry, a moiety is a part of a molecule.
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N-Acetylglucosamine
N-Acetylglucosamine (N-acetyl-D-glucosamine, or GlcNAc, or NAG) is a monosaccharide and a derivative of glucose.
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N-acetylglucosamine-1-phosphate transferase
N-acetylglucosamine-1-phosphate transferase is a transferase enzyme.
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Protein precursor
A protein precursor, also called a pro-protein or pro-peptide, is an inactive protein (or peptide) that can be turned into an active form by post-translational modification, such as breaking off a piece of the molecule or adding on another molecule.
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Uridine diphosphate
Uridine diphosphate, abbreviated UDP, is a nucleotide diphosphate.
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Redirects here:
D-mannose 6-phosphate, M6P, Man-6-P, Mannose-6-phosphate, Mannose-six-phosphate.
References
[1] https://en.wikipedia.org/wiki/Mannose_6-phosphate
