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Neural stem cell

Index Neural stem cell

Neural stem cells (NSCs) are self-renewing, multipotent cells that generate the neurons and glia of the nervous system of all animals during embryonic development. [1]

79 relations: Adult stem cell, Ageing, Apoptosis, Astrocyte, Asymmetric cell division, Blood–brain barrier, Cell potency, Cellular differentiation, Central nervous system, Cerebral cortex, Chemokine, Collagen, Constance Cepko, Cytotoxicity, Dentate gyrus, Doublecortin, Embryogenesis, Embryonic stem cell, Ependyma, Epidermal growth factor, Excitotoxicity, Fibroblast growth factor, FOX proteins, Galectin-1, Gel, Granule cell, Hes3 signaling axis, Hippocampus, Homeostasis, Huntington's disease, Immunodeficiency, In vitro, Inflammation, Integrin, Ischemia, Jaime Imitola, Joseph Altman, Lentivirus, List of human cell types derived from the germ layers, Microglia, Midbrain, Mitogen, Multiple sclerosis, N-Myc, Necrosis, Nervous system, Nestin (protein), NeuN, Neuroblast, Neuroepithelial cell, ..., Neurogenesis, Neuroglia, Neuron, Neuroprotection, Neurosphere, Olfactory bulb, Oligodendrocyte, Oncogene, Parkinson's disease, PDF, Progenitor cell, Radial glial cell, Rostral migratory stream, Sally Temple, Samuel Weiss, Spinal cord, Stem cell, Stemcell Technologies, Striatum, Stroke, Stromal cell-derived factor 1, Subventricular zone, The Journal of Neuroscience, Traumatic brain injury, Ventricular system, Ventricular zone, Vertebrate, Wnt signaling pathway, Xenotransplantation. Expand index (29 more) »

Adult stem cell

Adult stem cells are undifferentiated cells, found throughout the body after development, that multiply by cell division to replenish dying cells and regenerate damaged tissues.

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Ageing

Ageing or aging (see spelling differences) is the process of becoming older.

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Apoptosis

Apoptosis (from Ancient Greek ἀπόπτωσις "falling off") is a process of programmed cell death that occurs in multicellular organisms.

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Astrocyte

Astrocytes (Astro from Greek astron.

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Asymmetric cell division

An asymmetric cell division produces two daughter cells with different cellular fates.

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Blood–brain barrier

The blood–brain barrier (BBB) is a highly selective semipermeable membrane barrier that separates the circulating blood from the brain and extracellular fluid in the central nervous system (CNS).

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Cell potency

Cell potency is a cell's ability to differentiate into other cell types The more cell types a cell can differentiate into, the greater its potency.

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Cellular differentiation

In developmental biology, cellular differentiation is the process where a cell changes from one cell type to another.

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Central nervous system

The central nervous system (CNS) is the part of the nervous system consisting of the brain and spinal cord.

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Cerebral cortex

The cerebral cortex is the largest region of the cerebrum in the mammalian brain and plays a key role in memory, attention, perception, cognition, awareness, thought, language, and consciousness.

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Chemokine

Chemokines (Greek -kinos, movement) are a family of small cytokines, or signaling proteins secreted by cells.

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Collagen

Collagen is the main structural protein in the extracellular space in the various connective tissues in animal bodies.

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Constance Cepko

Constance Louise Cepko is a developmental biologist and geneticist in Harvard Medical School.

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Cytotoxicity

Cytotoxicity is the quality of being toxic to cells.

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Dentate gyrus

The dentate gyrus is part of a brain region known as the hippocampus (part of the hippocampal formation).

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Doublecortin

Neuronal migration protein doublecortin, also known as doublin or lissencephalin-X is a protein that in humans is encoded by the DCX gene.

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Embryogenesis

Embryogenesis is the process by which the embryo forms and develops.

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Embryonic stem cell

Embryonic stem cells (ES cells or ESCs) are pluripotent stem cells derived from the inner cell mass of a blastocyst, an early-stage pre-implantation embryo.

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Ependyma

Ependyma is the thin neuroepithelial lining of the ventricular system of the brain and the central canal of the spinal cord, made up of ependymal cells.

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Epidermal growth factor

Epidermal growth factor (EGF) stimulates cell growth and differentiation by binding to its receptor, EGFR.

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Excitotoxicity

Excitotoxicity is the pathological process by which nerve cells are damaged or killed by excessive stimulation by neurotransmitters such as glutamate and similar substances.

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Fibroblast growth factor

The fibroblast growth factors are a family of cell signalling proteins that are involved in a wide variety of processes, most notably as crucial elements for normal development.

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FOX proteins

FOX (Forkhead box) proteins are a family of transcription factors that play important roles in regulating the expression of genes involved in cell growth, proliferation, differentiation, and longevity.

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Galectin-1

Galectin-1 is a protein that in humans is encoded by the LGALS1 gene.

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Gel

A gel is a solid jelly-like material that can have properties ranging from soft and weak to hard and tough.

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Granule cell

The name granule cell has been used by anatomists for a number of different types of neuron whose only common feature is that they all have very small cell bodies.

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Hes3 signaling axis

The STAT3-Ser/Hes3 signaling axis is a specific type of intracellular signaling pathway that regulates several fundamental properties of cells.

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Hippocampus

The hippocampus (named after its resemblance to the seahorse, from the Greek ἱππόκαμπος, "seahorse" from ἵππος hippos, "horse" and κάμπος kampos, "sea monster") is a major component of the brains of humans and other vertebrates.

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Homeostasis

Homeostasis is the tendency of organisms to auto-regulate and maintain their internal environment in a stable state.

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Huntington's disease

Huntington's disease (HD), also known as Huntington's chorea, is an inherited disorder that results in death of brain cells.

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Immunodeficiency

Immunodeficiency (or immune deficiency) is a state in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent.

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In vitro

In vitro (meaning: in the glass) studies are performed with microorganisms, cells, or biological molecules outside their normal biological context.

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Inflammation

Inflammation (from inflammatio) is part of the complex biological response of body tissues to harmful stimuli, such as pathogens, damaged cells, or irritants, and is a protective response involving immune cells, blood vessels, and molecular mediators.

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Integrin

Integrins are transmembrane receptors that facilitate cell-extracellular matrix (ECM) adhesion.

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Ischemia

Ischemia or ischaemia is a restriction in blood supply to tissues, causing a shortage of oxygen that is needed for cellular metabolism (to keep tissue alive).

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Jaime Imitola

Jaime Imitola is a Neuroscientist, neuroimmunologist and stem cell researcher, known for his work on the impact of inflammation in the endogenous neural stem cell function and molecular programs, work that has contributed to the understanding of the neurodegeneration and the lack of repair in chronic neurological diseases including multiple sclerosis.

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Joseph Altman

Joseph Altman (1925 – 2016) was an American biologist who worked in the field of neurobiology.

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Lentivirus

Lentivirus (lente-, Latin for "slow") is a genus of retroviruses that cause chronic and deadly diseases characterized by long incubation periods, in the human and other mammalian species.

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List of human cell types derived from the germ layers

This is a list of cells in humans derived from the germ layers, which includes the ectoderm, mesoderm, and endoderm.

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Microglia

Microglia are a type of neuroglia (glial cell) located throughout the brain and spinal cord.

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Midbrain

The midbrain or mesencephalon (from Greek mesos 'middle', and enkephalos 'brain') is a portion of the central nervous system associated with vision, hearing, motor control, sleep/wake, arousal (alertness), and temperature regulation.

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Mitogen

A mitogen is a chemical substance that encourages a cell to commence cell division, triggering mitosis.

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Multiple sclerosis

Multiple sclerosis (MS) is a demyelinating disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged.

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N-Myc

N-myc proto-oncogene protein also known as N-Myc or basic helix-loop-helix protein 37 (bHLHe37), is a protein that in humans is encoded by the MYCN gene.

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Necrosis

Necrosis (from the Greek νέκρωσις "death, the stage of dying, the act of killing" from νεκρός "dead") is a form of cell injury which results in the premature death of cells in living tissue by autolysis.

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Nervous system

The nervous system is the part of an animal that coordinates its actions by transmitting signals to and from different parts of its body.

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Nestin (protein)

Nestin is a protein that in humans is encoded by the NES gene.

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NeuN

NeuN (Feminizing Locus on X-3, Fox-3, Rbfox3, or Hexaribonucleotide Binding Protein-3), a homologue to sex-determining genes in Caenorhabditis elegans, is a neuronal nuclear antigen that is commonly used as a biomarker for neurons.

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Neuroblast

A neuroblast or primitive nerve cell is a dividing cell that will develop into a neuron often after a migration phase.

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Neuroepithelial cell

Neuroepithelial cells are the "stem cells" of the nervous system, deriving from actual stem cells in several different stages of neural development.

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Neurogenesis

Neurogenesis is the process by which nervous system cells, known as neurons, are produced by neural stem cells (NSC)s, and it occurs in all species of animals except the porifera (sponges) and placozoans.

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Neuroglia

Neuroglia, also called glial cells or simply glia, are non-neuronal cells in the central nervous system (brain and spinal cord) and the peripheral nervous system.

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Neuron

A neuron, also known as a neurone (British spelling) and nerve cell, is an electrically excitable cell that receives, processes, and transmits information through electrical and chemical signals.

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Neuroprotection

Neuroprotection refers to the relative preservation of neuronal structure and/or function.

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Neurosphere

A neurosphere is a culture system composed of free-floating clusters of neural stem cells.

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Olfactory bulb

The olfactory bulb (bulbus olfactorius) is a neural structure of the vertebrate forebrain involved in olfaction, the sense of smell.

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Oligodendrocyte

Oligodendrocytes, or oligodendroglia,.

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Oncogene

An oncogene is a gene that has the potential to cause cancer.

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Parkinson's disease

Parkinson's disease (PD) is a long-term degenerative disorder of the central nervous system that mainly affects the motor system.

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PDF

The Portable Document Format (PDF) is a file format developed in the 1990s to present documents, including text formatting and images, in a manner independent of application software, hardware, and operating systems.

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Progenitor cell

A progenitor cell is a biological cell that, like a stem cell, has a tendency to differentiate into a specific type of cell, but is already more specific than a stem cell and is pushed to differentiate into its "target" cell.

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Radial glial cell

Radial glial cells are bipolar-shaped cells that span the width of the cortex in the developing vertebrate central nervous system (CNS) and serve as primary progenitor cells capable of generating neurons, astrocytes, and oligodendrocytes.

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Rostral migratory stream

The rostral migratory stream (RMS) is a specialized migratory route found in the brain of some animals along which neuronal precursors that originated in the subventricular zone (SVZ) of the brain migrate to reach the main olfactory bulb (OB).

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Sally Temple

Sally Temple is an American developmental neuroscientist in Albany, New York.

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Samuel Weiss

Samuel Weiss is a neurobiologist.

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Spinal cord

The spinal cord is a long, thin, tubular bundle of nervous tissue and support cells that extends from the medulla oblongata in the brainstem to the lumbar region of the vertebral column.

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Stem cell

Stem cells are biological cells that can differentiate into other types of cells and can divide to produce more of the same type of stem cells.

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Stemcell Technologies

STEMCELL Technologies Inc.

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Striatum

The striatum, or corpus striatum (also called the neostriatum and the striate nucleus) is a nucleus (a cluster of neurons) in the subcortical basal ganglia of the forebrain.

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Stroke

A stroke is a medical condition in which poor blood flow to the brain results in cell death.

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Stromal cell-derived factor 1

The stromal cell-derived factor 1 (SDF1), also known as C-X-C motif chemokine 12 (CXCL12), is a chemokine protein that in humans is encoded by the CXCL12 gene on chromosome 10.

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Subventricular zone

The subventricular zone (SVZ) is a term used to describe both embryonic and adult neural tissues in the vertebrate central nervous system (CNS).

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The Journal of Neuroscience

The Journal of Neuroscience is a weekly peer-reviewed scientific journal published by the Society for Neuroscience.

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Traumatic brain injury

Traumatic brain injury (TBI), also known as intracranial injury, occurs when an external force injures the brain.

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Ventricular system

The ventricular system is a set of four interconnected cavities (ventricles) in the brain, where the cerebrospinal fluid (CSF) is produced.

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Ventricular zone

In vertebrate organisms, the ventricular zone (VZ) is a transient embryonic layer of tissue containing neural stem cells, principally radial glial cells, of the central nervous system (CNS).

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Vertebrate

Vertebrates comprise all species of animals within the subphylum Vertebrata (chordates with backbones).

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Wnt signaling pathway

The Wnt signaling pathways are a group of signal transduction pathways made of proteins that pass signals into a cell through cell surface receptors.

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Xenotransplantation

Xenotransplantation (xenos- from the Greek meaning "foreign"), is the transplantation of living cells, tissues or organs from one species to another.

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Redirects here:

Cellula nervosa praecursoria, Cellula nervosa precursoria, Cellulae nervosae praecursoriae, Cellulae nervosae precursoriae, Neural stem cells.

References

[1] https://en.wikipedia.org/wiki/Neural_stem_cell

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