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AaTX1

Index AaTX1

AaTX1 is a scorpion toxin of the α-KTx15 subfamily originally found in the venom of Androctonus australis. The toxin acts as a specific blocker on Kv4.3 voltage-gated potassium channel, thereby abolishing the A-type potassium currents. [1]

23 relations: Alpha helix, Amino acid, AmmTX3, Androctonus australis, Antiparallel (biochemistry), Beta sheet, BmTx3, Cross-link, Cysteine, Discrepin, Disulfide, Dopamine, Fattail scorpion, KCND3, Mass concentration (chemistry), Middle East, Molecular mass, North Africa, Peptide, Potassium channel, Scorpion toxin, Substantia nigra, Venom.

Alpha helix

The alpha helix (α-helix) is a common motif in the secondary structure of proteins and is a righthand-spiral conformation (i.e. helix) in which every backbone N−H group donates a hydrogen bond to the backbone C.

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Amino acid

Amino acids are organic compounds containing amine (-NH2) and carboxyl (-COOH) functional groups, along with a side chain (R group) specific to each amino acid.

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AmmTX3

AmmTX3, produced by Androctonus mauretanicus, is a scorpion toxin of the α-KTX15 subfamily.

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Androctonus australis

Androctonus australis is a hardy desert scorpion from North Africa, Somalia, the Middle East, Pakistan and India.

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Antiparallel (biochemistry)

In biochemistry, two biopolymers are antiparallel if they run parallel to each other but with opposite alignments.

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Beta sheet

The β-sheet (also β-pleated sheet) is a common motif of regular secondary structure in proteins.

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BmTx3

BmTx3 is a neurotoxin, which is a component of the venom of the scorpion Buthus Martensi Karsch.

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Cross-link

A cross-link is a bond that links one polymer chain to another.

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Cysteine

Cysteine (symbol Cys or C) is a semi-essential proteinogenic amino acid with the formula HO2CCH(NH2)CH2SH.

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Discrepin

Discrepin (α-KTx15.6) is a peptide from the venom of the Venezuelan scorpion Tityus discrepans.

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Disulfide

In chemistry, a disulfide refers to a functional group with the structure R−S−S−R′.

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Dopamine

Dopamine (DA, a contraction of 3,4-dihydroxyphenethylamine) is an organic chemical of the catecholamine and phenethylamine families that plays several important roles in the brain and body.

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Fattail scorpion

Fattail scorpion or fat-tailed scorpion is the common name given to scorpions of the genus Androctonus, one of the most dangerous groups of scorpions species in the world.

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KCND3

Potassium voltage-gated channel subfamily D member 3 also known as Kv4.3 is a protein that in humans is encoded by the KCND3 gene.

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Mass concentration (chemistry)

In chemistry, the mass concentration is defined as the mass of a constituent divided by the volume of the mixture: For a pure chemical the mass concentration equals its density (mass divided by volume); thus the mass concentration of a component in a mixture can be called the density of a component in a mixture.

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Middle East

The Middle Easttranslit-std; translit; Orta Şərq; Central Kurdish: ڕۆژھەڵاتی ناوین, Rojhelatî Nawîn; Moyen-Orient; translit; translit; translit; Rojhilata Navîn; translit; Bariga Dhexe; Orta Doğu; translit is a transcontinental region centered on Western Asia, Turkey (both Asian and European), and Egypt (which is mostly in North Africa).

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Molecular mass

Relative Molecular mass or molecular weight is the mass of a molecule.

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North Africa

North Africa is a collective term for a group of Mediterranean countries and territories situated in the northern-most region of the African continent.

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Peptide

Peptides (from Gr.: πεπτός, peptós "digested"; derived from πέσσειν, péssein "to digest") are short chains of amino acid monomers linked by peptide (amide) bonds.

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Potassium channel

Potassium channels are the most widely distributed type of ion channel and are found in virtually all living organisms.

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Scorpion toxin

Scorpion toxins are proteins found in the venom of scorpions.

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Substantia nigra

The substantia nigra (SN) is a basal ganglia structure located in the midbrain that plays an important role in reward and movement.

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Venom

Venomous Animals Venom is a form of toxin secreted by an animal for the purpose of causing harm to another.

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References

[1] https://en.wikipedia.org/wiki/AaTX1

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