Table of Contents
14 relations: Alzheimer's disease, Amyloid, Amyloid beta, Amyloid plaques, Beta-secretase 1, Feed forward (control), Gene, Gene expression, Genetically modified mouse, Human, Long non-coding RNA, Messenger RNA, Non-coding RNA, RNA.
Alzheimer's disease
Alzheimer's disease (AD) is a neurodegenerative disease that usually starts slowly and progressively worsens, and is the cause of 60–70% of cases of dementia.
See BACE1-AS and Alzheimer's disease
Amyloid
Amyloids are aggregates of proteins characterised by a fibrillar morphology of typically 7–13 nm in diameter, a β-sheet secondary structure (known as cross-β) and ability to be stained by particular dyes, such as Congo red.
Amyloid beta
Amyloid beta (Aβ or Abeta) denotes peptides of 36–43 amino acids that are the main component of the amyloid plaques found in the brains of people with Alzheimer's disease. BACE1-AS and amyloid beta are Alzheimer's disease.
Amyloid plaques
Amyloid plaques (also known as neuritic plaques, amyloid beta plaques or senile plaques) are extracellular deposits of the amyloid beta (Aβ) protein mainly in the grey matter of the brain.
See BACE1-AS and Amyloid plaques
Beta-secretase 1
Beta-secretase 1, also known as beta-site amyloid precursor protein cleaving enzyme 1, beta-site APP cleaving enzyme 1 (BACE1), membrane-associated aspartic protease 2, memapsin-2, aspartyl protease 2, and ASP2, is an enzyme that in humans is encoded by the BACE1 gene. BACE1-AS and beta-secretase 1 are Alzheimer's disease and genes on human chromosome 11.
See BACE1-AS and Beta-secretase 1
Feed forward (control)
A feed forward (sometimes written feedforward) is an element or pathway within a control system that passes a controlling signal from a source in its external environment to a load elsewhere in its external environment.
See BACE1-AS and Feed forward (control)
Gene
In biology, the word gene has two meanings.
Gene expression
Gene expression is the process by which information from a gene is used in the synthesis of a functional gene product that enables it to produce end products, proteins or non-coding RNA, and ultimately affect a phenotype.
See BACE1-AS and Gene expression
Genetically modified mouse
A genetically modified mouse or genetically engineered mouse model (GEMM) is a mouse (Mus musculus) that has had its genome altered through the use of genetic engineering techniques.
See BACE1-AS and Genetically modified mouse
Human
Humans (Homo sapiens, meaning "thinking man") or modern humans are the most common and widespread species of primate, and the last surviving species of the genus Homo.
Long non-coding RNA
Long non-coding RNAs (long ncRNAs, lncRNA) are a type of RNA, generally defined as transcripts more than 200 nucleotides that are not translated into protein. BACE1-AS and Long non-coding RNA are non-coding RNA and RNA.
See BACE1-AS and Long non-coding RNA
Messenger RNA
In molecular biology, messenger ribonucleic acid (mRNA) is a single-stranded molecule of RNA that corresponds to the genetic sequence of a gene, and is read by a ribosome in the process of synthesizing a protein. BACE1-AS and messenger RNA are RNA.
See BACE1-AS and Messenger RNA
Non-coding RNA
A non-coding RNA (ncRNA) is a functional RNA molecule that is not translated into a protein. BACE1-AS and non-coding RNA are RNA.
See BACE1-AS and Non-coding RNA
RNA
Ribonucleic acid (RNA) is a polymeric molecule that is essential for most biological functions, either by performing the function itself (non-coding RNA) or by forming a template for the production of proteins (messenger RNA).
See BACE1-AS and RNA