Faster access than browser!
14 relations: Cambridge Antibody Technology, CCL11, Crohn's disease, Eosinophil, Herzliya, Human, Inflammatory bowel disease, Keratoconjunctivitis, Lonza Group, Monoclonal antibody, Phage display, Slough, Ulcerative colitis, United Kingdom.
Cambridge Antibody Technology
Cambridge Antibody Technology (officially Cambridge Antibody Technology Group Plc, informally CAT) was a biotechnology company headquartered in Cambridge, England, United Kingdom.
New!!: Bertilimumab and Cambridge Antibody Technology · See more »
CCL11
C-C motif chemokine 11 also known as eosinophil chemotactic protein and eotaxin-1 is a protein that in humans is encoded by the CCL11 gene.
New!!: Bertilimumab and CCL11 · See more »
Crohn's disease
Crohn's disease is a type of inflammatory bowel disease (IBD) that may affect any part of the gastrointestinal tract from mouth to anus.
New!!: Bertilimumab and Crohn's disease · See more »
Eosinophil
Eosinophils sometimes called eosinophiles or, less commonly, acidophils, are a variety of white blood cells and one of the immune system components responsible for combating multicellular parasites and certain infections in vertebrates. Along with mast cells and basophils, they also control mechanisms associated with allergy and asthma. They are granulocytes that develop during hematopoiesis in the bone marrow before migrating into blood, after which they are terminally differentiated and do not multiply. These cells are eosinophilic or "acid-loving" due to their large acidophilic cytoplasmic granules, which show their affinity for acids by their affinity to coal tar dyes: Normally transparent, it is this affinity that causes them to appear brick-red after staining with eosin, a red dye, using the Romanowsky method. The staining is concentrated in small granules within the cellular cytoplasm, which contain many chemical mediators, such as eosinophil peroxidase, ribonuclease (RNase), deoxyribonucleases (DNase), lipase, plasminogen, and major basic protein. These mediators are released by a process called degranulation following activation of the eosinophil, and are toxic to both parasite and host tissues. In normal individuals, eosinophils make up about 1–3% of white blood cells, and are about 12–17 micrometres in size with bilobed nuclei. While they are released into the bloodstream as neutrophils are, eosinophils reside in tissue They are found in the medulla and the junction between the cortex and medulla of the thymus, and, in the lower gastrointestinal tract, ovary, uterus, spleen, and lymph nodes, but not in the lung, skin, esophagus, or some other internal organs under normal conditions. The presence of eosinophils in these latter organs is associated with disease. For instance, patients with eosinophilic asthma have high levels of eosinophils that lead to inflammation and tissue damage, making it more difficult for patients to breathe. Eosinophils persist in the circulation for 8–12 hours, and can survive in tissue for an additional 8–12 days in the absence of stimulation. Pioneering work in the 1980s elucidated that eosinophils were unique granulocytes, having the capacity to survive for extended periods of time after their maturation as demonstrated by ex-vivo culture experiments.
New!!: Bertilimumab and Eosinophil · See more »
Herzliya
Herzliya (הֶרְצְלִיָּה; هرتسيليا) is an affluent city in the central coast of Israel, at the Northern part of the Tel Aviv District known for its robust start-up and entrepreneurial culture.
New!!: Bertilimumab and Herzliya · See more »
Human
Humans (taxonomically Homo sapiens) are the only extant members of the subtribe Hominina.
New!!: Bertilimumab and Human · See more »
Inflammatory bowel disease
Inflammatory bowel disease (IBD) is a group of inflammatory conditions of the colon and small intestine.
New!!: Bertilimumab and Inflammatory bowel disease · See more »
Keratoconjunctivitis
Keratoconjunctivitis is inflammation ("-itis") of the cornea and conjunctiva.
New!!: Bertilimumab and Keratoconjunctivitis · See more »
Lonza Group
Lonza Group is a Swiss multinational, chemicals and biotechnology company, headquartered in Basel, with major facilities in Europe, North America and South Asia.
New!!: Bertilimumab and Lonza Group · See more »
Monoclonal antibody
Monoclonal antibodies (mAb or moAb) are antibodies that are made by identical immune cells that are all clones of a unique parent cell.
New!!: Bertilimumab and Monoclonal antibody · See more »
Phage display
Phage display is a laboratory technique for the study of protein–protein, protein–peptide, and protein–DNA interactions that uses bacteriophages (viruses that infect bacteria) to connect proteins with the genetic information that encodes them.
New!!: Bertilimumab and Phage display · See more »
Slough
Slough is a large town in Berkshire, England, on the western fringes of the Greater London Urban Area, west of central London, north of Windsor, east of Maidenhead, south-east of High Wycombe and north-east of the county town of Reading.
New!!: Bertilimumab and Slough · See more »
Ulcerative colitis
Ulcerative colitis (UC) is a long-term condition that results in inflammation and ulcers of the colon and rectum.
New!!: Bertilimumab and Ulcerative colitis · See more »
United Kingdom
The United Kingdom of Great Britain and Northern Ireland, commonly known as the United Kingdom (UK) or Britain,Usage is mixed with some organisations, including the and preferring to use Britain as shorthand for Great Britain is a sovereign country in western Europe.
New!!: Bertilimumab and United Kingdom · See more »
