Table of Contents
196 relations: Abciximab, Acute myeloid leukemia, Adalimumab, Affinity chromatography, Agarose, Albumin, Alemtuzumab, Amino acid, Aminopterin, Anaphylaxis, Anemia, Angiogenesis inhibitor, Angioplasty, Anion-exchange chromatography, Ankylosing spondylitis, Antibody, Antibody-dependent cellular cytotoxicity, Antigen, Apoptosis, Ascites, Asthma, Autoimmune disease, Auxotrophy, Élie Metchnikoff, B cell, Bamlanivimab/etesevimab, Basiliximab, Bavituximab, Bevacizumab, Bioavailability, Biochemistry, Bispecific monoclonal antibody, Cancer, Cancer immunotherapy, Casirivimab/imdevimab, César Milstein, CD20, CD33, CD52, Cell culture, Cell fusion, Cetuximab, Chromatography, CiteAb, Cloning, Coagulation, Cochrane (organisation), Colorectal cancer, Complement-dependent cytotoxicity, Coronavirus, ... Expand index (146 more) »
- Reagents for biochemistry
- Therapeutic antibodies
Abciximab
Abciximab, a glycoprotein IIb/IIIa receptor antagonist manufactured by Janssen Biologics BV and distributed by Eli Lilly under the trade name ReoPro, is a platelet aggregation inhibitor mainly used during and after coronary artery procedures like angioplasty to prevent platelets from sticking together and causing thrombus (blood clot) formation within the coronary artery. Monoclonal antibody and Abciximab are monoclonal antibodies.
See Monoclonal antibody and Abciximab
Acute myeloid leukemia
Acute myeloid leukemia (AML) is a cancer of the myeloid line of blood cells, characterized by the rapid growth of abnormal cells that build up in the bone marrow and blood and interfere with normal blood cell production.
See Monoclonal antibody and Acute myeloid leukemia
Adalimumab
Adalimumab, sold under the brand name Humira and others, is a disease-modifying antirheumatic drug and monoclonal antibody used to treat rheumatoid arthritis, juvenile idiopathic arthritis, psoriatic arthritis, ankylosing spondylitis, Crohn's disease, ulcerative colitis, plaque psoriasis, hidradenitis suppurativa, and uveitis. Monoclonal antibody and Adalimumab are monoclonal antibodies.
See Monoclonal antibody and Adalimumab
Affinity chromatography
Affinity chromatography is a method of separating a biomolecule from a mixture, based on a highly specific macromolecular binding interaction between the biomolecule and another substance.
See Monoclonal antibody and Affinity chromatography
Agarose
Agarose is a heteropolysaccharide, generally extracted from certain red algae.
See Monoclonal antibody and Agarose
Albumin
Albumin is a family of globular proteins, the most common of which are the serum albumins.
See Monoclonal antibody and Albumin
Alemtuzumab
Alemtuzumab, sold under the brand names Campath and Lemtrada among others, is a medication used to treat chronic lymphocytic leukemia and multiple sclerosis.
See Monoclonal antibody and Alemtuzumab
Amino acid
Amino acids are organic compounds that contain both amino and carboxylic acid functional groups.
See Monoclonal antibody and Amino acid
Aminopterin
Aminopterin (or 4-aminopteroic acid), the 4–amino derivative of folic acid, is an antineoplastic drug with immunosuppressive properties often used in chemotherapy.
See Monoclonal antibody and Aminopterin
Anaphylaxis
Anaphylaxis (Greek: ana- ‘against’ + phylaxis ‘guarding’) is a serious, potentially fatal allergic reaction and medical emergency that is rapid in onset and requires immediate medical attention regardless of the use of emergency medication on site.
See Monoclonal antibody and Anaphylaxis
Anemia
Anemia or anaemia (British English) is a blood disorder in which the blood has a reduced ability to carry oxygen.
See Monoclonal antibody and Anemia
Angiogenesis inhibitor
An angiogenesis inhibitor is a substance that inhibits the growth of new blood vessels (angiogenesis).
See Monoclonal antibody and Angiogenesis inhibitor
Angioplasty
Angioplasty, also known as balloon angioplasty and percutaneous transluminal angioplasty (PTA), is a minimally invasive endovascular procedure used to widen narrowed or obstructed arteries or veins, typically to treat arterial atherosclerosis.
See Monoclonal antibody and Angioplasty
Anion-exchange chromatography
Anion-exchange chromatography is a process that separates substances based on their charges using an ion-exchange resin containing positively charged groups, such as diethyl-aminoethyl groups (DEAE).
See Monoclonal antibody and Anion-exchange chromatography
Ankylosing spondylitis
Ankylosing spondylitis (AS) is a type of arthritis characterized by long-term inflammation of the joints of the spine, typically where the spine joins the pelvis.
See Monoclonal antibody and Ankylosing spondylitis
Antibody
An antibody (Ab) is the secreted form of a B cell receptor; the term immunoglobulin (Ig) can refer to either the membrane-bound form or the secreted form of the B cell receptor, but they are, broadly speaking, the same protein, and so the terms are often treated as synonymous. Monoclonal antibody and antibody are immunology and Reagents for biochemistry.
See Monoclonal antibody and Antibody
Antibody-dependent cellular cytotoxicity
Antibody-dependent cellular cytotoxicity (ADCC), also referred to as antibody-dependent cell-mediated cytotoxicity, is a mechanism of cell-mediated immune defense whereby an effector cell of the immune system kills a target cell, whose membrane-surface antigens have been bound by specific antibodies. Monoclonal antibody and antibody-dependent cellular cytotoxicity are immune system.
See Monoclonal antibody and Antibody-dependent cellular cytotoxicity
Antigen
In immunology, an antigen (Ag) is a molecule, moiety, foreign particulate matter, or an allergen, such as pollen, that can bind to a specific antibody or T-cell receptor. Monoclonal antibody and antigen are immune system.
See Monoclonal antibody and Antigen
Apoptosis
Apoptosis (from falling off) is a form of programmed cell death that occurs in multicellular organisms and in some eukaryotic, single-celled microorganisms such as yeast. Monoclonal antibody and Apoptosis are immunology.
See Monoclonal antibody and Apoptosis
Ascites
Ascites (translit, meaning "bag" or "sac") is the abnormal build-up of fluid in the abdomen.
See Monoclonal antibody and Ascites
Asthma
Asthma is a long-term inflammatory disease of the airways of the lungs.
See Monoclonal antibody and Asthma
Autoimmune disease
An autoimmune disease is a condition that results from an anomalous response of the adaptive immune system, wherein it mistakenly targets and attacks healthy, functioning parts of the body as if they were foreign organisms.
See Monoclonal antibody and Autoimmune disease
Auxotrophy
Auxotrophy (αὐξάνω "to increase"; τροφή "nourishment") is the inability of an organism to synthesize a particular organic compound required for its growth (as defined by IUPAC).
See Monoclonal antibody and Auxotrophy
Élie Metchnikoff
Ilya Ilyich Mechnikov (Илья Ильич Мечников; – 15 July 1916), also spelled Élie Metchnikoff, was a zoologist from the Russian Empire of Moldavian noble ancestry and also at archive.org best known for his pioneering research in immunology (study of immune systems) and thanatology (study of death).
See Monoclonal antibody and Élie Metchnikoff
B cell
B cells, also known as B lymphocytes, are a type of white blood cell of the lymphocyte subtype. Monoclonal antibody and b cell are immune system and immunology.
See Monoclonal antibody and B cell
Bamlanivimab/etesevimab
Bamlanivimab/etesevimab is a combination of two monoclonal antibodies, bamlanivimab and etesevimab, administered together via intravenous infusion as a treatment for COVID-19. Monoclonal antibody and Bamlanivimab/etesevimab are monoclonal antibodies.
See Monoclonal antibody and Bamlanivimab/etesevimab
Basiliximab
Basiliximab, sold under the brand name Simulect, is a monoclonal antibody used to prevent rejection in kidney transplants.
See Monoclonal antibody and Basiliximab
Bavituximab
Bavituximab (PGN401) is a human-mouse chimeric monoclonal antibody against phosphatidylserine, which is a component of cell membranes that is exposed when a cell is transformed into solid tumor cancer cell or dies, and when cells are infected with hepatitis C. The process of cell death is highly controlled and so there usually no immune response to phosphatidylserine but when bavituximab binds to it, the conjugate appears to stimulate an immune response in humans.
See Monoclonal antibody and Bavituximab
Bevacizumab
Bevacizumab, sold under the brand name Avastin among others, is a monoclonal antibody medication used to treat a number of types of cancers and a specific eye disease.
See Monoclonal antibody and Bevacizumab
Bioavailability
In pharmacology, bioavailability is a subcategory of absorption and is the fraction (%) of an administered drug that reaches the systemic circulation.
See Monoclonal antibody and Bioavailability
Biochemistry
Biochemistry or biological chemistry is the study of chemical processes within and relating to living organisms. Monoclonal antibody and Biochemistry are Biotechnology.
See Monoclonal antibody and Biochemistry
Bispecific monoclonal antibody
A bispecific monoclonal antibody (BsMAb, BsAb) is an artificial protein that can simultaneously bind to two different types of antigen or two different epitopes on the same antigen. Monoclonal antibody and bispecific monoclonal antibody are monoclonal antibodies.
See Monoclonal antibody and Bispecific monoclonal antibody
Cancer
Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body.
See Monoclonal antibody and Cancer
Cancer immunotherapy
Cancer immunotherapy (immuno-oncotherapy) is the stimulation of the immune system to treat cancer, improving the immune system's natural ability to fight the disease. Monoclonal antibody and cancer immunotherapy are cancer treatments.
See Monoclonal antibody and Cancer immunotherapy
Casirivimab/imdevimab
Casirivimab/imdevimab, sold under the brand name REGEN‑COV among others, Text was copied from this source which is copyright European Medicines Agency. Monoclonal antibody and Casirivimab/imdevimab are monoclonal antibodies.
See Monoclonal antibody and Casirivimab/imdevimab
César Milstein
César Milstein, CH, FRS (8 October 1927 – 24 March 2002) was an Argentine biochemist in the field of antibody research.
See Monoclonal antibody and César Milstein
CD20
B-lymphocyte antigen CD20 or CD20 is B lymphocyte cell-surface molecule.
See Monoclonal antibody and CD20
CD33
CD33 or Siglec-3 (sialic acid binding Ig-like lectin 3, SIGLEC3, SIGLEC-3, gp67, p67) is a transmembrane receptor expressed on cells of myeloid lineage.
See Monoclonal antibody and CD33
CD52
CAMPATH-1 antigen, also known as cluster of differentiation 52 (CD52), is a glycoprotein that in humans is encoded by the CD52 gene.
See Monoclonal antibody and CD52
Cell culture
Cell culture or tissue culture is the process by which cells are grown under controlled conditions, generally outside of their natural environment. Monoclonal antibody and cell culture are Biotechnology.
See Monoclonal antibody and Cell culture
Cell fusion
Cell fusion is an important cellular process in which several uninucleate cells (cells with a single nucleus) combine to form a multinucleate cell, known as a syncytium.
See Monoclonal antibody and Cell fusion
Cetuximab
Cetuximab, sold under the brand name Erbitux, is an epidermal growth factor receptor (EGFR) inhibitor medication used for the treatment of metastatic colorectal cancer and head and neck cancer.
See Monoclonal antibody and Cetuximab
Chromatography
In chemical analysis, chromatography is a laboratory technique for the separation of a mixture into its components.
See Monoclonal antibody and Chromatography
CiteAb
CiteAb Limited is a life science data company located in Bath, England that offers an antibody, biochemicals, experimental models, kits and protein search tool to aid biomedical scientists in their research.
See Monoclonal antibody and CiteAb
Cloning
Cloning is the process of producing individual organisms with identical genomes, either by natural or artificial means. Monoclonal antibody and Cloning are Biotechnology.
See Monoclonal antibody and Cloning
Coagulation
Coagulation, also known as clotting, is the process by which blood changes from a liquid to a gel, forming a blood clot.
See Monoclonal antibody and Coagulation
Cochrane (organisation)
Cochrane is a British international charitable organisation formed to synthesize medical research findings to facilitate evidence-based choices about health interventions involving health professionals, patients and policy makers.
See Monoclonal antibody and Cochrane (organisation)
Colorectal cancer
Colorectal cancer (CRC), also known as bowel cancer, colon cancer, or rectal cancer, is the development of cancer from the colon or rectum (parts of the large intestine).
See Monoclonal antibody and Colorectal cancer
Complement-dependent cytotoxicity
Complement-dependent cytotoxicity (CDC) is an effector function of IgG and IgM antibodies. Monoclonal antibody and Complement-dependent cytotoxicity are immunology.
See Monoclonal antibody and Complement-dependent cytotoxicity
Coronavirus
Coronaviruses are a group of related RNA viruses that cause diseases in mammals and birds.
See Monoclonal antibody and Coronavirus
COVID-19
Coronavirus disease 2019 (COVID-19) is a contagious disease caused by the coronavirus SARS-CoV-2.
See Monoclonal antibody and COVID-19
COVID-19 pandemic
The COVID-19 pandemic (also known as the coronavirus pandemic), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), began with an outbreak of COVID-19 in Wuhan, China, in December 2019.
See Monoclonal antibody and COVID-19 pandemic
CRISPR
CRISPR (an acronym for clustered regularly interspaced short palindromic repeats) is a family of DNA sequences found in the genomes of prokaryotic organisms such as bacteria and archaea. Monoclonal antibody and CRISPR are Biotechnology and immune system.
See Monoclonal antibody and CRISPR
Crohn's disease
Crohn's disease is a type of inflammatory bowel disease (IBD) that may affect any segment of the gastrointestinal tract.
See Monoclonal antibody and Crohn's disease
Cysteine
Cysteine (symbol Cys or C) is a semiessential proteinogenic amino acid with the formula.
See Monoclonal antibody and Cysteine
Cytokine
Cytokines are a broad and loose category of small proteins (~5–25 kDa) important in cell signaling. Monoclonal antibody and Cytokine are immune system and immunology.
See Monoclonal antibody and Cytokine
Daclizumab
Daclizumab (trade name Zinbryta) is a therapeutic humanized monoclonal antibody which was used for the treatment of adults with relapsing forms of multiple sclerosis (MS). Monoclonal antibody and Daclizumab are monoclonal antibodies.
See Monoclonal antibody and Daclizumab
De novo synthesis
In chemistry, de novo synthesis is the synthesis of complex molecules from simple molecules such as sugars or amino acids, as opposed to recycling after partial degradation.
See Monoclonal antibody and De novo synthesis
Deamidation
Deamidation is a chemical reaction in which an amide functional group in the side chain of the amino acids asparagine or glutamine is removed or converted to another functional group.
See Monoclonal antibody and Deamidation
Dialysis (chemistry)
In chemistry, dialysis is the process of separating molecules in solution by the difference in their rates of diffusion through a semipermeable membrane, such as dialysis tubing.
See Monoclonal antibody and Dialysis (chemistry)
Diarrhea
Diarrhea (American English), also spelled diarrhoea or diarrhœa (British English), is the condition of having at least three loose, liquid, or watery bowel movements in a day.
See Monoclonal antibody and Diarrhea
Dihydrofolate reductase
Dihydrofolate reductase, or DHFR, is an enzyme that reduces dihydrofolic acid to tetrahydrofolic acid, using NADPH as an electron donor, which can be converted to the kinds of tetrahydrofolate cofactors used in 1-carbon transfer chemistry.
See Monoclonal antibody and Dihydrofolate reductase
Displacement chromatography
Displacement chromatography is a chromatography technique in which a sample is placed onto the head of the column and is then displaced by a solute that is more strongly sorbed than the components of the original mixture.
See Monoclonal antibody and Displacement chromatography
Dostarlimab
Dostarlimab, sold under the brand name Jemperli, is a monoclonal antibody used as an anti-cancer medication for the treatment of endometrial cancer.
See Monoclonal antibody and Dostarlimab
Dot blot
A dot blot (or slot blot) is a technique in molecular biology used to detect proteins.
See Monoclonal antibody and Dot blot
ELISA
The enzyme-linked immunosorbent assay (ELISA) is a commonly used analytical biochemistry assay, first described by Eva Engvall and Peter Perlmann in 1971.
See Monoclonal antibody and ELISA
Elution
In analytical and organic chemistry, elution is the process of extracting one material from another by washing with a solvent: washing of loaded ion-exchange resins to remove captured ions, or eluting proteins or other biopolymers from a gel electrophoresis or chromatography column.
See Monoclonal antibody and Elution
Emergency Use Authorization
An Emergency Use Authorization (EUA) in the United States is an authorization granted to the Food and Drug Administration (FDA) under sections of the Federal Food, Drug, and Cosmetic Act as added to and amended by various Acts of Congress, including by the Pandemic and All-Hazards Preparedness Reauthorization Act of 2013 (PAHPRA), as codified by, to allow the use of a drug prior to approval.
See Monoclonal antibody and Emergency Use Authorization
Enterocolitis
Enterocolitis is an inflammation of the digestive tract, involving enteritis of the small intestine and colitis of the colon.
See Monoclonal antibody and Enterocolitis
Epidermal growth factor receptor
The epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is a transmembrane protein that is a receptor for members of the epidermal growth factor family (EGF family) of extracellular protein ligands.
See Monoclonal antibody and Epidermal growth factor receptor
Epitope
An epitope, also known as antigenic determinant, is the part of an antigen that is recognized by the immune system, specifically by antibodies, B cells, or T cells.
See Monoclonal antibody and Epitope
Ethics
Ethics is the philosophical study of moral phenomena.
See Monoclonal antibody and Ethics
Filtration
Filtration is a physical separation process that separates solid matter and fluid from a mixture using a filter medium that has a complex structure through which only the fluid can pass.
See Monoclonal antibody and Filtration
Folate
Folate, also known as vitamin B9 and folacin, is one of the B vitamins.
See Monoclonal antibody and Folate
Food and Drug Administration
The United States Food and Drug Administration (FDA or US FDA) is a federal agency of the Department of Health and Human Services.
See Monoclonal antibody and Food and Drug Administration
Fragment antigen-binding region
The fragment antigen-binding region (Fab region) is a region on an antibody that binds to antigens.
See Monoclonal antibody and Fragment antigen-binding region
Fragment crystallizable region
The fragment crystallizable region (Fc region) is the tail region of an antibody that interacts with cell surface receptors called Fc receptors and some proteins of the complement system. Monoclonal antibody and fragment crystallizable region are immunology.
See Monoclonal antibody and Fragment crystallizable region
Gastrointestinal perforation
Gastrointestinal perforation, also known as gastrointestinal rupture, is a hole in the wall of the gastrointestinal tract. The gastrointestinal tract is composed of hollow digestive organs leading from the mouth to the anus.
See Monoclonal antibody and Gastrointestinal perforation
Gemtuzumab ozogamicin
Gemtuzumab ozogamicin, sold under the brand name Mylotarg, is an antibody-drug conjugate (a drug-linked monoclonal antibody) that is used to treat acute myeloid leukemia.
See Monoclonal antibody and Gemtuzumab ozogamicin
Genetically modified mouse
A genetically modified mouse or genetically engineered mouse model (GEMM) is a mouse (Mus musculus) that has had its genome altered through the use of genetic engineering techniques.
See Monoclonal antibody and Genetically modified mouse
Georges J. F. Köhler
Georges Jean Franz Köhler (17 April 1946 – 1 March 1995) was a German biologist.
See Monoclonal antibody and Georges J. F. Köhler
Glycoprotein IIb/IIIa
In biochemistry and medicine, glycoprotein IIb/IIIa (GPIIb/IIIa, also known as integrin αIIbβ3) is an integrin complex found on platelets.
See Monoclonal antibody and Glycoprotein IIb/IIIa
Glycosylation
Glycosylation is the reaction in which a carbohydrate (or 'glycan'), i.e. a glycosyl donor, is attached to a hydroxyl or other functional group of another molecule (a glycosyl acceptor) in order to form a glycoconjugate.
See Monoclonal antibody and Glycosylation
Gregory Winter
Sir Gregory Paul Winter (born 14 April 1951) is a Nobel Prize-winning English molecular biologist best known for his work on the therapeutic use of monoclonal antibodies.
See Monoclonal antibody and Gregory Winter
Hashimoto's thyroiditis
Hashimoto's thyroiditis, also known as chronic lymphocytic thyroiditis and Hashimoto's disease, is an autoimmune disease in which the thyroid gland is gradually destroyed.
See Monoclonal antibody and Hashimoto's thyroiditis
HAT medium
HAT Medium (hypoxanthine-aminopterin-thymidine medium) is a selection medium for mammalian cell culture, which relies on the combination of aminopterin, a drug that acts as a powerful folate metabolism inhibitor by inhibiting dihydrofolate reductase, with hypoxanthine (a purine derivative) and thymidine (a deoxynucleoside) which are intermediates in DNA synthesis.
See Monoclonal antibody and HAT medium
Hepatitis C
Hepatitis C is an infectious disease caused by the hepatitis C virus (HCV) that primarily affects the liver; it is a type of viral hepatitis.
See Monoclonal antibody and Hepatitis C
HER2
Receptor tyrosine-protein kinase erbB-2 is a protein that normally resides in the membranes of cells and is encoded by the ERBB2 gene. Monoclonal antibody and HER2 are cancer treatments.
See Monoclonal antibody and HER2
Hives
Hives, also known as urticaria, is a kind of skin rash with red, raised, itchy bumps.
See Monoclonal antibody and Hives
Hormone
A hormone (from the Greek participle ὁρμῶν, "setting in motion") is a class of signaling molecules in multicellular organisms that are sent to distant organs or tissues by complex biological processes to regulate physiology and behavior.
See Monoclonal antibody and Hormone
House mouse
The house mouse (Mus musculus) is a small mammal of the order Rodentia, characteristically having a pointed snout, large rounded ears, and a long and almost hairless tail.
See Monoclonal antibody and House mouse
Human anti-mouse antibody
Human anti-mouse antibody or human anti-murine antibody (HAMA) is an antibody found in humans which reacts to immunoglobins found in mice. Monoclonal antibody and human anti-mouse antibody are monoclonal antibodies and therapeutic antibodies.
See Monoclonal antibody and Human anti-mouse antibody
Humanized antibody
Humanized antibodies are antibodies from non-human species whose protein sequences have been modified to increase their similarity to antibody variants produced naturally in humans. Monoclonal antibody and Humanized antibody are monoclonal antibodies.
See Monoclonal antibody and Humanized antibody
Hybridoma technology
Hybridoma technology is a method for producing large numbers of identical antibodies, also called monoclonal antibodies. Monoclonal antibody and Hybridoma technology are immunology.
See Monoclonal antibody and Hybridoma technology
Hypothyroidism
Hypothyroidism (also called underactive thyroid, low thyroid or hypothyreosis) is a disorder of the endocrine system in which the thyroid gland does not produce enough thyroid hormones.
See Monoclonal antibody and Hypothyroidism
Hypoxanthine
Hypoxanthine is a naturally occurring purine derivative.
See Monoclonal antibody and Hypoxanthine
Hypoxanthine-guanine phosphoribosyltransferase
Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) is an enzyme encoded in humans by the HPRT1 gene.
See Monoclonal antibody and Hypoxanthine-guanine phosphoribosyltransferase
Immunofluorescence
Immunofluorescence (IF) is a light microscopy-based technique that allows detection and localization of a wide variety of target biomolecules within a cell or tissue at a quantitative level. Monoclonal antibody and Immunofluorescence are Reagents for biochemistry.
See Monoclonal antibody and Immunofluorescence
Immunogenicity
Immunogenicity is the ability of a foreign substance, such as an antigen, to provoke an immune response in the body of a human or other animal. Monoclonal antibody and Immunogenicity are immunology.
See Monoclonal antibody and Immunogenicity
Immunoglobulin E
Immunoglobulin E (IgE) is a type of antibody (or immunoglobulin (Ig) "isotype") that has been found only in mammals.
See Monoclonal antibody and Immunoglobulin E
Immunohistochemistry
Immunohistochemistry is a form of immunostaining. Monoclonal antibody and Immunohistochemistry are immunology.
See Monoclonal antibody and Immunohistochemistry
Immunology
Immunology is a branch of biology and medicine that covers the study of immune systems in all organisms.
See Monoclonal antibody and Immunology
Immunoprecipitation
Immunoprecipitation (IP) is the technique of precipitating a protein antigen out of solution using an antibody that specifically binds to that particular protein.
See Monoclonal antibody and Immunoprecipitation
Immunotherapy
Immunotherapy or biological therapy is the treatment of disease by activating or suppressing the immune system. Monoclonal antibody and Immunotherapy are immunology.
See Monoclonal antibody and Immunotherapy
In vitro
In vitro (meaning in glass, or in the glass) studies are performed with microorganisms, cells, or biological molecules outside their normal biological context.
See Monoclonal antibody and In vitro
Inflammation
Inflammation (from inflammatio) is part of the biological response of body tissues to harmful stimuli, such as pathogens, damaged cells, or irritants. Monoclonal antibody and inflammation are immunology.
See Monoclonal antibody and Inflammation
Infliximab
Infliximab, a chimeric monoclonal antibody, sold under the brand name Remicade among others, is a medication used to treat a number of autoimmune diseases. Monoclonal antibody and Infliximab are monoclonal antibodies.
See Monoclonal antibody and Infliximab
Interleukin
Interleukins (ILs) are a group of cytokines (secreted proteins and signal molecules) that are expressed and secreted by white blood cells (leukocytes) as well as some other body cells.
See Monoclonal antibody and Interleukin
Interleukin 12
Interleukin 12 (IL-12) is an interleukin that is naturally produced by dendritic cells, macrophages, neutrophils, helper T cells and human B-lymphoblastoid cells (NC-37) in response to antigenic stimulation.
See Monoclonal antibody and Interleukin 12
Interleukin 2
Interleukin-2 (IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system. Monoclonal antibody and interleukin 2 are cancer treatments and immunology.
See Monoclonal antibody and Interleukin 2
Interleukin 23
Interleukin 23 (IL-23) is a heterodimeric cytokine composed of an IL-12B (IL-12p40) subunit (which is shared with IL-12) and an IL-23A (IL-23p19) subunit.
See Monoclonal antibody and Interleukin 23
Ion
An ion is an atom or molecule with a net electrical charge.
See Monoclonal antibody and Ion
Ion chromatography
Ion chromatography (or ion-exchange chromatography) is a form of chromatography that separates ions and ionizable polar molecules based on their affinity to the ion exchanger.
See Monoclonal antibody and Ion chromatography
Ipilimumab
Ipilimumab, sold under the brand name Yervoy, is a monoclonal antibody medication that works to activate the immune system by targeting CTLA-4, a protein receptor that downregulates the immune system.
See Monoclonal antibody and Ipilimumab
Isoelectric point
The isoelectric point (pI, pH(I), IEP), is the pH at which a molecule carries no net electrical charge or is electrically neutral in the statistical mean.
See Monoclonal antibody and Isoelectric point
James P. Allison
James Patrick Allison (born August 7, 1948) is an American immunologist and Nobel laureate who holds the position of professor and chair of immunology and executive director of immunotherapy platform at the MD Anderson Cancer Center in Houston, Texas.
See Monoclonal antibody and James P. Allison
Jerrold Schwaber
Jerrold Schwaber (May 24, 1947 – June 6, 2014) was an American biologist and geneticist.
See Monoclonal antibody and Jerrold Schwaber
Keyhole limpet hemocyanin
Keyhole limpet hemocyanin (KLH) is a large, multisubunit, oxygen-carrying, metalloprotein that is found in the hemolymph of the giant keyhole limpet, Megathura crenulata, a species of keyhole limpet that lives off the coast of California, from Monterey Bay to Isla Asuncion off Baja California.
See Monoclonal antibody and Keyhole limpet hemocyanin
Leukemia
Leukemia (also spelled leukaemia; pronounced) is a group of blood cancers that usually begin in the bone marrow and produce high numbers of abnormal blood cells.
See Monoclonal antibody and Leukemia
Lineage (evolution)
An evolutionary lineage is a temporal series of populations, organisms, cells, or genes connected by a continuous line of descent from ancestor to descendant.
See Monoclonal antibody and Lineage (evolution)
Lipopolysaccharide
Lipopolysaccharide, now more commonly known as Endotoxin, is a collective term for components of the outermost membrane of cell envelope of Gram-negative bacteria, such as E. coli and Salmonella.
See Monoclonal antibody and Lipopolysaccharide
List of therapeutic monoclonal antibodies
Therapeutic, diagnostic and preventive monoclonal antibodies are clones of a single parent cell. Monoclonal antibody and List of therapeutic monoclonal antibodies are immunology and monoclonal antibodies.
See Monoclonal antibody and List of therapeutic monoclonal antibodies
Lymphocyte
A lymphocyte is a type of white blood cell (leukocyte) in the immune system of most vertebrates. Monoclonal antibody and lymphocyte are immune system.
See Monoclonal antibody and Lymphocyte
Lymphoid leukemia
Lymphoid leukemias are a group of leukemias affecting circulating lymphocytes, a type of white blood cell.
See Monoclonal antibody and Lymphoid leukemia
Magic bullet (medicine)
The magic bullet is a scientific concept developed by the German Nobel laureate Paul Ehrlich in 1907.
See Monoclonal antibody and Magic bullet (medicine)
Medicine
Medicine is the science and practice of caring for patients, managing the diagnosis, prognosis, prevention, treatment, palliation of their injury or disease, and promoting their health.
See Monoclonal antibody and Medicine
Membrane fouling
Membrane fouling is a process whereby a solution or a particle is deposited on a membrane surface or in membrane pores in a processes such as in a membrane bioreactor, reverse osmosis, forward osmosis, membrane distillation, ultrafiltration, microfiltration, or nanofiltration so that the membrane's performance is degraded.
See Monoclonal antibody and Membrane fouling
Molecular biology
Molecular biology is a branch of biology that seeks to understand the molecular basis of biological activity in and between cells, including biomolecular synthesis, modification, mechanisms, and interactions.
See Monoclonal antibody and Molecular biology
Monoclonal antibody therapy
Monoclonal antibodies (mAbs) have varied therapeutic uses. Monoclonal antibody and Monoclonal antibody therapy are immunology and monoclonal antibodies.
See Monoclonal antibody and Monoclonal antibody therapy
Monoclonality
In biology, monoclonality refers to the state of a line of cells that have been derived from a single clonal origin.
See Monoclonal antibody and Monoclonality
Mucositis
Mucositis is the painful inflammation and ulceration of the mucous membranes lining the digestive tract, usually as an adverse effect of chemotherapy and radiotherapy treatment for cancer.
See Monoclonal antibody and Mucositis
Multiple myeloma
Multiple myeloma (MM), also known as plasma cell myeloma and simply myeloma, is a cancer of plasma cells, a type of white blood cell that normally produces antibodies.
See Monoclonal antibody and Multiple myeloma
Murinae
The Old World rats and mice, part of the subfamily Murinae in the family Muridae, comprise at least 519 species.
See Monoclonal antibody and Murinae
Myeloma protein
A myeloma protein is an abnormal antibody (immunoglobulin) or (more often) a fragment thereof, such as an immunoglobulin light chain, that is produced in excess by an abnormal monoclonal proliferation of plasma cells, typically in multiple myeloma or Monoclonal gammopathy of undetermined significance. Monoclonal antibody and myeloma protein are immune system.
See Monoclonal antibody and Myeloma protein
Niels Kaj Jerne
Niels Kaj Jerne, FRS (23 December 1911 – 7 October 1994) was a Danish immunologist.
See Monoclonal antibody and Niels Kaj Jerne
Nimotuzumab
Nimotuzumab (h-R3, BIOMAb EGFR, Biocon, India; TheraCIM, CIMYM Biosciences, Canada; Theraloc, Oncoscience, Europe, CIMAher, Center of Molecular Immunology, Havana, Cuba) is a humanized monoclonal antibody that as of 2014 had orphan status in the US and EU for glioma, and marketing approval in India, China, and other countries for squamous cell carcinomas of the head and neck, and was undergoing several clinical trials.
See Monoclonal antibody and Nimotuzumab
Nivolumab
Nivolumab, sold under the brand name Opdivo, is an anti-cancer medication used to treat a number of types of cancer.
See Monoclonal antibody and Nivolumab
Nobel Prize in Physiology or Medicine
The Nobel Prize in Physiology or Medicine (Nobelpriset i fysiologi eller medicin) is awarded yearly by the Nobel Assembly at the Karolinska Institute for outstanding discoveries in physiology or medicine.
See Monoclonal antibody and Nobel Prize in Physiology or Medicine
Non-Hodgkin lymphoma
Non-Hodgkin lymphoma (NHL), also known as non-Hodgkin's lymphoma, is a group of blood cancers that includes all types of lymphomas except Hodgkin lymphomas.
See Monoclonal antibody and Non-Hodgkin lymphoma
Nuclease
In biochemistry, a nuclease (also archaically known as nucleodepolymerase or polynucleotidase) is an enzyme capable of cleaving the phosphodiester bonds between nucleotides of nucleic acids.
See Monoclonal antibody and Nuclease
Nucleic acid
Nucleic acids are large biomolecules that are crucial in all cells and viruses.
See Monoclonal antibody and Nucleic acid
Nucleotide salvage
A salvage pathway is a pathway in which a biological product is produced from intermediates in the degradative pathway of its own or a similar substance.
See Monoclonal antibody and Nucleotide salvage
Ofatumumab
Ofatumumab is a fully human monoclonal antibody to CD20, which appears to provide rapid B-cell depletion.
See Monoclonal antibody and Ofatumumab
Palivizumab
Palivizumab, sold under the brand name Synagis, is a monoclonal antibody produced by recombinant DNA technology used to prevent severe disease caused by respiratory syncytial virus (RSV) infections. Monoclonal antibody and Palivizumab are Biotechnology and monoclonal antibodies.
See Monoclonal antibody and Palivizumab
Panitumumab
Panitumumab, sold under the brand name Vectibix, is a fully human monoclonal antibody specific to the epidermal growth factor receptor (also known as EGF receptor, EGFR, ErbB-1 and HER1 in humans).
See Monoclonal antibody and Panitumumab
Paul Ehrlich
Paul Ehrlich (14 March 1854 – 20 August 1915) was a Nobel Prize-winning German physician and scientist who worked in the fields of hematology, immunology and antimicrobial chemotherapy.
See Monoclonal antibody and Paul Ehrlich
Pembrolizumab
Pembrolizumab, sold under the brand name Keytruda, is a humanized antibody used in cancer immunotherapy that treats melanoma, lung cancer, head and neck cancer, Hodgkin lymphoma, stomach cancer, cervical cancer, and certain types of breast cancer.
See Monoclonal antibody and Pembrolizumab
Pemivibart
Pemivibart, sold under the brand name Pemgarda, is a monoclonal antibody medication authorized for the pre-exposure prophylaxis (prevention) of COVIDnbhyph19.
See Monoclonal antibody and Pemivibart
Peptide
Peptides are short chains of amino acids linked by peptide bonds.
See Monoclonal antibody and Peptide
Peritoneum
The peritoneum is the serous membrane forming the lining of the abdominal cavity or coelom in amniotes and some invertebrates, such as annelids.
See Monoclonal antibody and Peritoneum
PH
In chemistry, pH, also referred to as acidity or basicity, historically denotes "potential of hydrogen" (or "power of hydrogen").
See Monoclonal antibody and PH
Phage display
Phage display is a laboratory technique for the study of protein–protein, protein–peptide, and protein–DNA interactions that uses bacteriophages (viruses that infect bacteria) to connect proteins with the genetic information that encodes them.
See Monoclonal antibody and Phage display
Pharmacokinetics
Pharmacokinetics (from Ancient Greek pharmakon "drug" and kinetikos "moving, putting in motion"; see chemical kinetics), sometimes abbreviated as PK, is a branch of pharmacology dedicated to describing how the body affects a specific substance after administration.
See Monoclonal antibody and Pharmacokinetics
Phosphatidylserine
Phosphatidylserine (abbreviated Ptd-L-Ser or PS) is a phospholipid and is a component of the cell membrane.
See Monoclonal antibody and Phosphatidylserine
Plasma cell
Plasma cells, also called plasma B cells or effector B cells, are white blood cells that originate in the lymphoid organs as B cells and secrete large quantities of proteins called antibodies in response to being presented specific substances called antigens. Monoclonal antibody and plasma cell are immune system and immunology.
See Monoclonal antibody and Plasma cell
Platelet
Platelets or thrombocytes are a blood component whose function (along with the coagulation factors) is to react to bleeding from blood vessel injury by clumping, thereby initiating a blood clot.
See Monoclonal antibody and Platelet
Polyclonal antibodies
Polyclonal antibodies (pAbs) are antibodies that are secreted by different B cell lineages within the body (whereas monoclonal antibodies come from a single cell lineage). Monoclonal antibody and Polyclonal antibodies are Biotechnology, immune system, immunology, Reagents for biochemistry and therapeutic antibodies.
See Monoclonal antibody and Polyclonal antibodies
Polyethylene glycol
Polyethylene glycol (PEG) is a polyether compound derived from petroleum with many applications, from industrial manufacturing to medicine.
See Monoclonal antibody and Polyethylene glycol
Pre-exposure prophylaxis
Pre-exposure prophylaxis (PrEP), is the use of medications to prevent the spread of disease in people who have not yet been exposed to a disease-causing agent.
See Monoclonal antibody and Pre-exposure prophylaxis
Protease
A protease (also called a peptidase, proteinase, or proteolytic enzyme) is an enzyme that catalyzes proteolysis, breaking down proteins into smaller polypeptides or single amino acids, and spurring the formation of new protein products.
See Monoclonal antibody and Protease
Protein A
Protein A is a 42 kDa surface protein originally found in the cell wall of the bacteria Staphylococcus aureus.
See Monoclonal antibody and Protein A
Protein A/G
Protein A/G is a recombinant fusion protein that combines IgG binding domains of both protein A and protein G. Protein A/G contains four Fc binding domains from protein A and two from protein G, yielding a final mass of 50,460 daltons.
See Monoclonal antibody and Protein A/G
Psoriasis
Psoriasis is a long-lasting, noncontagious autoimmune disease characterized by patches of abnormal skin.
See Monoclonal antibody and Psoriasis
Psoriatic arthritis
Psoriatic arthritis (PsA) is a long-term inflammatory arthritis that occurs in people affected by the autoimmune disease psoriasis.
See Monoclonal antibody and Psoriatic arthritis
Quality by design
Quality by design (QbD) is a concept first outlined by quality expert Joseph M. Juran in publications, most notably Juran on Quality by Design.
See Monoclonal antibody and Quality by design
Rabbit hybridoma
A rabbit hybridoma is a hybrid cell line formed by the fusion of an antibody producing rabbit B cell with a cancerous B-cell (myeloma). Monoclonal antibody and rabbit hybridoma are Biotechnology, immune system, immunology, monoclonal antibodies and therapeutic antibodies.
See Monoclonal antibody and Rabbit hybridoma
Radionuclide
A radionuclide (radioactive nuclide, radioisotope or radioactive isotope) is a nuclide that has excess numbers of either neutrons or protons, giving it excess nuclear energy, and making it unstable.
See Monoclonal antibody and Radionuclide
Ranibizumab
Ranibizumab, sold under the brand name Lucentis among others, is a monoclonal antibody fragment (Fab) created from the same parent mouse antibody as bevacizumab. Monoclonal antibody and Ranibizumab are monoclonal antibodies.
See Monoclonal antibody and Ranibizumab
Recombinant DNA
Recombinant DNA (rDNA) molecules are DNA molecules formed by laboratory methods of genetic recombination (such as molecular cloning) that bring together genetic material from multiple sources, creating sequences that would not otherwise be found in the genome.
See Monoclonal antibody and Recombinant DNA
Respiratory syncytial virus
Respiratory syncytial virus (RSV), also called human respiratory syncytial virus (hRSV) and human orthopneumovirus, is a contagious virus that causes infections of the respiratory tract.
See Monoclonal antibody and Respiratory syncytial virus
Rheumatoid arthritis
Rheumatoid arthritis (RA) is a long-term autoimmune disorder that primarily affects joints.
See Monoclonal antibody and Rheumatoid arthritis
Rituximab
Rituximab, sold under the brand name Rituxan among others, is a monoclonal antibody medication used to treat certain autoimmune diseases and types of cancer.
See Monoclonal antibody and Rituximab
SARS-CoV-2
Severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) is a strain of coronavirus that causes COVID-19, the respiratory illness responsible for the COVID-19 pandemic.
See Monoclonal antibody and SARS-CoV-2
Size-exclusion chromatography
Size-exclusion chromatography, also known as molecular sieve chromatography, is a chromatographic method in which molecules in solution are separated by their size, and in some cases molecular weight.
See Monoclonal antibody and Size-exclusion chromatography
Sotrovimab
Sotrovimab, sold under the brand name Xevudy, is a human neutralizing monoclonal antibody with activity against severe acute respiratory syndrome coronavirus 2, known as SARS-CoV-2. Monoclonal antibody and Sotrovimab are monoclonal antibodies.
See Monoclonal antibody and Sotrovimab
Squamous-cell carcinoma
The term squamous-cell carcinoma (SCC), also known as epidermoid carcinoma, comprises a number of different types of cancer that begin in squamous cells.
See Monoclonal antibody and Squamous-cell carcinoma
Stomatitis
Stomatitis is inflammation of the mouth and lips.
See Monoclonal antibody and Stomatitis
T cell
T cells are one of the important types of white blood cells of the immune system and play a central role in the adaptive immune response. Monoclonal antibody and t cell are immune system and immunology.
See Monoclonal antibody and T cell
Tasuku Honjo
is a Japanese physician-scientist and immunologist.
See Monoclonal antibody and Tasuku Honjo
Thymidine
Thymidine (symbol dT or dThd), also known as deoxythymidine, deoxyribosylthymine, or thymine deoxyriboside, is a pyrimidine deoxynucleoside.
See Monoclonal antibody and Thymidine
Tixagevimab/cilgavimab
Tixagevimab/cilgavimab, sold under the brand name Evusheld, is a combination of two human monoclonal antibodies, tixagevimab (AZD8895) and cilgavimab (AZD1061) targeted against the surface spike protein of SARS-CoV-2 used to prevent COVID-19. Monoclonal antibody and Tixagevimab/cilgavimab are monoclonal antibodies.
See Monoclonal antibody and Tixagevimab/cilgavimab
Toxin
A toxin is a naturally occurring poison produced by metabolic activities of living cells or organisms.
See Monoclonal antibody and Toxin
Transferrin
Transferrins are glycoproteins found in vertebrates which bind and consequently mediate the transport of iron (Fe) through blood plasma.
See Monoclonal antibody and Transferrin
Transplant rejection
Transplant rejection occurs when transplanted tissue is rejected by the recipient's immune system, which destroys the transplanted tissue.
See Monoclonal antibody and Transplant rejection
Trastuzumab
Trastuzumab, sold under the brand name Herceptin among others, is a monoclonal antibody used to treat breast cancer and stomach cancer. Monoclonal antibody and Trastuzumab are immunology.
See Monoclonal antibody and Trastuzumab
Tumor necrosis factor
Tumor necrosis factor (TNF, cachexin, or cachectin; formerly known as tumor necrosis factor alpha, TNFα or TNF-α) is a cytokine and member of the TNF superfamily, which consists of various transmembrane proteins with a homologous TNF domain.
See Monoclonal antibody and Tumor necrosis factor
Ulcerative colitis
Ulcerative colitis (UC) is one of the two types of inflammatory bowel disease (IBD), with the other type being Crohn's disease.
See Monoclonal antibody and Ulcerative colitis
Ultrafiltration
Ultrafiltration (UF) is a variety of membrane filtration in which forces such as pressure or concentration gradients lead to a separation through a semipermeable membrane.
See Monoclonal antibody and Ultrafiltration
University of Pittsburgh
The University of Pittsburgh (also known as Pitt) is a public state-related research university in Pittsburgh, Pennsylvania, United States.
See Monoclonal antibody and University of Pittsburgh
Ustekinumab
Ustekinumab, sold under the brand name Stelara among others, is a monoclonal antibody medication developed by Janssen Pharmaceuticals, for the treatment of Crohn's disease, ulcerative colitis, plaque psoriasis and psoriatic arthritis, targeting both IL-12 and IL-23. Monoclonal antibody and Ustekinumab are monoclonal antibodies.
See Monoclonal antibody and Ustekinumab
Vascular endothelial growth factor
Vascular endothelial growth factor (VEGF), originally known as vascular permeability factor (VPF), is a signal protein produced by many cells that stimulates the formation of blood vessels.
See Monoclonal antibody and Vascular endothelial growth factor
Virus
A virus is a submicroscopic infectious agent that replicates only inside the living cells of an organism.
See Monoclonal antibody and Virus
Western blot
The western blot (sometimes called the protein immunoblot), or western blotting, is a widely used analytical technique in molecular biology and immunogenetics to detect specific proteins in a sample of tissue homogenate or extract.
See Monoclonal antibody and Western blot
White blood cell
White blood cells (scientific name leukocytes), also called immune cells or immunocytes, are cells of the immune system that are involved in protecting the body against both infectious disease and foreign invaders. Monoclonal antibody and White blood cell are immune system and immunology.
See Monoclonal antibody and White blood cell
Yeast
Yeasts are eukaryotic, single-celled microorganisms classified as members of the fungus kingdom.
See Monoclonal antibody and Yeast
Yeast display
Yeast display (or yeast surface display) is a protein engineering technique that uses the expression of recombinant proteins incorporated into the cell wall of yeast.
See Monoclonal antibody and Yeast display
See also
Reagents for biochemistry
- 1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide
- 1-Hydroxy-7-azabenzotriazole
- 3-Azidocoumarin
- 7-Chlorokynurenic acid
- Antibody
- Antibody Solutions
- Antibody microarray
- BOP reagent
- Biotin PEG2 amine
- Biotin hydrazide
- Blocking antibody
- DEPBT
- Direct fluorescent antibody
- Ellman's reagent
- Ethyl cyanohydroxyiminoacetate
- FI6 (antibody)
- Fluorenylmethyloxycarbonyl chloride
- Hydroxybenzotriazole
- Immunofluorescence
- Lowry protein assay
- Maltoside
- Mono-BOC-cystamine
- Monoclonal antibody
- N,N'-Dicyclohexylcarbodiimide
- N,N'-Diisopropylcarbodiimide
- N-Ethylmaleimide
- Polyclonal antibodies
- PyAOP reagent
- PyBOP
- Reagent
- Sodium dodecyl sulfate
- Succinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate
- Ub-AMC
Therapeutic antibodies
- Antibody-drug conjugates
- Antitoxins
- Burosumab
- Human anti-mouse antibody
- Immunoglobulin therapy
- Monoclonal antibodies
- Monoclonal antibody
- Oligoclonal antibody
- Passive antibody therapy
- Plantibody
- Polyclonal antibodies
- Rabbit hybridoma
- Telitacicept
References
Also known as 2IT-BAD monoclonal antibody 170, A33 monoclonal antibody, Antibodies, monoclonal, Antibody engineering, Chimerized MAb, Human monoclonal antibodies, Human monoclonal antibody, Humanised antibodies, M Ab, MAb, MAbs, MoAb, Monoclonal antibodies, Monoclonals.