200 relations: ABCC4, Acetate, Acetic acid, Acetoacetate decarboxylase, Acetoacetic acid, Acetone, Acetyl-CoA, Acetyl-CoA carboxylase, Acyl carrier protein, Acyl CoA dehydrogenase, Acyl-CoA, Adenosine monophosphate, Adenosine triphosphate, Adipocyte, Adipose tissue, Adrenaline, Albumin, Alicyclic compound, Allosteric regulation, Alpha-Linolenic acid, Anabolism, Anhydrous, Animal, Anterior pituitary, Arachidonic acid, ATP citrate lyase, ATP-binding cassette transporter, Autocrine signalling, Beta oxidation, Beta-Hydroxybutyric acid, Beta-ketoacyl-acyl-carrier-protein synthase I, Bile acid, Blood plasma, Blood–brain barrier, Calorie, Carbon, Carnitine palmitoyltransferase I, Carnitine palmitoyltransferase II, Carnitine-acylcarnitine translocase, Catabolism, Cell (biology), Cell membrane, Cell nucleus, Cell wall, Central nervous system, Cholesterol, Chylomicron, Citric acid, Citric acid cycle, Coenzyme A, ..., Colipase, Cyclooxygenase, Cyclopentane, CYP2E1, Cytosol, Diglyceride, Dihydroxyacetone phosphate, Eicosanoid, Emulsion, Endocrine system, Endoplasmic reticulum, Endothelium, Enoyl-acyl carrier protein reductase, Enoyl-CoA hydratase, Enterocyte, Enzyme, Escherichia coli, Essential fatty acid, Extracellular fluid, Fat, Fatty acid, Fatty acid synthase, Fatty acid synthesis, Fatty-acid metabolism disorder, Flavin adenine dinucleotide, Formate, Gastrointestinal tract, Glucagon, Gluconeogenesis, Glucose, Glyceraldehyde 3-phosphate, Glycerol, Glycerol 3-phosphate, Glycerol kinase, Glycogen, Glycolysis, Golgi apparatus, Gram, Guanosine triphosphate, Hibernation, Hormone, Hydrocarbon, Hydrolysis, Hydrophobe, Hydroxyacetone, Hydroxyeicosatetraenoic acid, Hyperlipidemia, Hypertriglyceridemia, Inborn error of lipid metabolism, Inborn errors of metabolism, Inflammation, Inner mitochondrial membrane, Inositol trisphosphate, Insulin, Intermediate-density lipoprotein, Isocitrate dehydrogenase, Isotopic labeling, Journal of Biological Chemistry, Ketoacidosis, Ketone bodies, Ketosis, Lactaldehyde, Lacteal, Lactic acid, Leukotriene, Lipase, Lipid, Lipid bilayer, Lipid storage disorder, Lipogenesis, Lipolysis, Lipoprotein lipase, Lipoxygenase, Liver, Long-chain-fatty-acid—CoA ligase, Low-density lipoprotein, Lymphatic system, Malic acid, Malonyl-CoA, Mammary gland, Methylglyoxal, Micelle, Mitochondrion, Molecule, Monoglyceride, Neuron, Nicotinamide adenine dinucleotide, Nicotinamide adenine dinucleotide phosphate, Norepinephrine, Nucleic acid, Nucleotide, Nutrient, Oleic acid, Organelle, Oxaloacetic acid, Oxoglutarate dehydrogenase complex, Palmitic acid, Pancreatic lipase family, Paracrine signalling, Pentose phosphate pathway, Phosphatidic acid, Phosphatidylinositol 4,5-bisphosphate, Phospholipase A2, Phospholipase C, Phospholipid, Phosphorylation, Physiology, Platelet, Portal vein, Pound (mass), Prokaryote, Prolactin, Propionaldehyde, Propionyl-CoA, Propylene glycol, Prostacyclin, Prostaglandin, Prostanoid, Protein kinase C, Pyruvate dehydrogenase complex, Pyruvic acid, Receptor (biochemistry), Red blood cell, Redox, Second messenger system, Secretion, Serine, SLCO2A1, Smooth muscle tissue, Solute carrier family, Steroid hormone, Sympathetic nervous system, Thiolase, Thoracic duct, Threonine, Thrombosis, Thromboxane, Tissue (biology), Transport protein, Triglyceride, Triosephosphate isomerase, Vasoconstriction, Vasodilation, Very low-density lipoprotein, Water, (acyl-carrier-protein) S-acetyltransferase, (acyl-carrier-protein) S-malonyltransferase, 3-Hydroxyacyl ACP dehydrase, 3-hydroxyacyl-CoA dehydrogenase, 3-oxoacyl-(acyl-carrier-protein) reductase. Expand index (150 more) »
ABCC4
ATP-binding cassette sub-family C member 4 (ABCC4), also known as the multidrug resistance-associated protein 4 (MRP4) or multi-specific organic anion transporter B (MOAT-B), is a protein that in humans is encoded by the ABCC4 gene.
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Acetate
An acetate is a salt formed by the combination of acetic acid with an alkaline, earthy, metallic or nonmetallic and other base.
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Acetic acid
Acetic acid, systematically named ethanoic acid, is a colourless liquid organic compound with the chemical formula CH3COOH (also written as CH3CO2H or C2H4O2).
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Acetoacetate decarboxylase
Acetoacetate decarboxylase (AAD or ADC) is an enzyme involved in both the ketone body production pathway in humans and other mammals, and solventogenesis in bacteria.
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Acetoacetic acid
Acetoacetic acid (also diacetic acid) is the organic compound with the formula CH3COCH2COOH.
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Acetone
Acetone (systematically named propanone) is the organic compound with the formula (CH3)2CO.
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Acetyl-CoA
Acetyl-CoA (acetyl coenzyme A) is a molecule that participates in many biochemical reactions in protein, carbohydrate and lipid metabolism.
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Acetyl-CoA carboxylase
Acetyl-CoA carboxylase (ACC) is a biotin-dependent enzyme that catalyzes the irreversible carboxylation of acetyl-CoA to produce malonyl-CoA through its two catalytic activities, biotin carboxylase (BC) and carboxyltransferase (CT).
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Acyl carrier protein
The acyl carrier protein (ACP) is an important component in both fatty acid and polyketide biosynthesis with the growing chain bound during synthesis as a thiol ester at the distal thiol of a 4'-phosphopantetheine moiety.
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Acyl CoA dehydrogenase
Acyl-CoA dehydrogenases (ACADs) are a class of enzymes that function to catalyze the initial step in each cycle of fatty acid β-oxidation in the mitochondria of cells.
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Acyl-CoA
Acyl-CoA is a group of coenzymes involved in the metabolism of fatty acids.
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Adenosine monophosphate
Adenosine monophosphate (AMP), also known as 5'-adenylic acid, is a nucleotide.
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Adenosine triphosphate
Adenosine triphosphate (ATP) is a complex organic chemical that participates in many processes.
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Adipocyte
Adipocytes, also known as lipocytes and fat cells, are the cells that primarily compose adipose tissue, specialized in storing energy as fat.
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Adipose tissue
In biology, adipose tissue, body fat, or simply fat is a loose connective tissue composed mostly of adipocytes.
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Adrenaline
Adrenaline, also known as adrenalin or epinephrine, is a hormone, neurotransmitter, and medication.
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Albumin
The albumins (formed from Latin: albumen "(egg) white; dried egg white") are a family of globular proteins, the most common of which are the serum albumins.
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Alicyclic compound
An alicyclic compound is an organic compound that is both aliphatic and cyclic.
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Allosteric regulation
In biochemistry, allosteric regulation (or allosteric control) is the regulation of an enzyme by binding an effector molecule at a site other than the enzyme's active site.
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Alpha-Linolenic acid
α-Linolenic acid (ALA) is an n−3 fatty acid.
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Anabolism
Anabolism (from ἁνά, "upward" and βάλλειν, "to throw") is the set of metabolic pathways that construct molecules from smaller units.
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Anhydrous
A substance is anhydrous if it contains no water.
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Animal
Animals are multicellular eukaryotic organisms that form the biological kingdom Animalia.
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Anterior pituitary
A major organ of the endocrine system, the anterior pituitary (also called the adenohypophysis or pars anterior), is the glandular, anterior lobe that together with the posterior lobe (posterior pituitary, or the neurohypophysis) makes up the pituitary gland (hypophysis).
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Arachidonic acid
Arachidonic acid (AA, sometimes ARA) is a polyunsaturated omega-6 fatty acid 20:4(ω-6).
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ATP citrate lyase
ATP citrate lyase is an enzyme that in animals represents an important step in fatty acid biosynthesis.
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ATP-binding cassette transporter
ATP-binding cassette transporters (ABC transporters) are members of a transport system superfamily that is one of the largest and is possibly one of the oldest families with representatives in all extant phyla from prokaryotes to humans.
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Autocrine signalling
Autocrine signaling is a form of cell signaling in which a cell secretes a hormone or chemical messenger (called the autocrine agent) that binds to autocrine receptors on that same cell, leading to changes in the cell.
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Beta oxidation
In biochemistry and metabolism, beta-oxidation is the catabolic process by which fatty acid molecules are broken down in the cytosol in prokaryotes and in the mitochondria in eukaryotes to generate acetyl-CoA, which enters the citric acid cycle, and NADH and FADH2, which are co-enzymes used in the electron transport chain.
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Beta-Hydroxybutyric acid
β-Hydroxybutyric acid, also known as 3-hydroxybutyric acid, is an organic compound and a beta hydroxy acid with the chemical formula CH3CH(OH)CH2CO2H; its conjugate base is β-hydroxybutyrate, also known as 3-hydroxybutyrate.
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Beta-ketoacyl-acyl-carrier-protein synthase I
In enzymology, a beta-ketoacyl-acyl-carrier-protein synthase I is an enzyme that catalyzes the chemical reaction Thus, the two substrates of this enzyme are acyl-acyl-carrier-protein and malonyl-acyl-carrier-protein, whereas its 3 products are 3-oxoacyl-acyl-carrier-protein, CO2, and acyl carrier protein.
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Bile acid
Bile acids are steroid acids found predominantly in the bile of mammals and other vertebrates.
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Blood plasma
Blood plasma is a yellowish coloured liquid component of blood that normally holds the blood cells in whole blood in suspension; this makes plasma the extracellular matrix of blood cells.
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Blood–brain barrier
The blood–brain barrier (BBB) is a highly selective semipermeable membrane barrier that separates the circulating blood from the brain and extracellular fluid in the central nervous system (CNS).
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Calorie
A calorie is a unit of energy.
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Carbon
Carbon (from carbo "coal") is a chemical element with symbol C and atomic number 6.
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Carnitine palmitoyltransferase I
Carnitine palmitoyltransferase I (CPT1) also known as carnitine acyltransferase I, CPTI, CAT1, CoA:carnitine acyl transferase (CCAT), or palmitoylCoA transferase I, is a mitochondrial enzyme responsible for the formation of acyl carnitines by catalyzing the transfer of the acyl group of a long-chain fatty acyl-CoA from coenzyme A to l-carnitine.
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Carnitine palmitoyltransferase II
Carnitine O-palmitoyltransferase 2, mitochondrial is an enzyme that in humans is encoded by the CPT2 gene.
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Carnitine-acylcarnitine translocase
Carnitine-acylcarnitine translocase is responsible for transporting both carnitine-fatty acid complexes and carnitine across the inner mitochondrial membrane.
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Catabolism
Catabolism (from Greek κάτω kato, "downward" and βάλλειν ballein, "to throw") is the set of metabolic pathways that breaks down molecules into smaller units that are either oxidized to release energy or used in other anabolic reactions.
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Cell (biology)
The cell (from Latin cella, meaning "small room") is the basic structural, functional, and biological unit of all known living organisms.
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Cell membrane
The cell membrane (also known as the plasma membrane or cytoplasmic membrane, and historically referred to as the plasmalemma) is a biological membrane that separates the interior of all cells from the outside environment (the extracellular space).
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Cell nucleus
In cell biology, the nucleus (pl. nuclei; from Latin nucleus or nuculeus, meaning kernel or seed) is a membrane-enclosed organelle found in eukaryotic cells.
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Cell wall
A cell wall is a structural layer surrounding some types of cells, just outside the cell membrane.
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Central nervous system
The central nervous system (CNS) is the part of the nervous system consisting of the brain and spinal cord.
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Cholesterol
Cholesterol (from the Ancient Greek chole- (bile) and stereos (solid), followed by the chemical suffix -ol for an alcohol) is an organic molecule.
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Chylomicron
Chylomicrons (from the Greek χυλός, chylos, meaning juice (of plants or animals), and micron, meaning small particle) are lipoprotein particles that consist of triglycerides (85–92%), phospholipids (6–12%), cholesterol (1–3%), and proteins (1–2%).
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Citric acid
Citric acid is a weak organic acid that has the chemical formula.
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Citric acid cycle
The citric acid cycle (CAC) – also known as the tricarboxylic acid (TCA) cycle or the Krebs cycle – is a series of chemical reactions used by all aerobic organisms to release stored energy through the oxidation of acetyl-CoA derived from carbohydrates, fats, and proteins into carbon dioxide and chemical energy in the form of adenosine triphosphate (ATP).
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Coenzyme A
Coenzyme A (CoA,SCoA,CoASH) is a coenzyme, notable for its role in the synthesis and oxidation of fatty acids, and the oxidation of pyruvate in the citric acid cycle.
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Colipase
Colipase is a protein co-enzyme required for optimal enzyme activity of pancreatic lipase.
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Cyclooxygenase
Cyclooxygenase (COX), officially known as prostaglandin-endoperoxide synthase (PTGS), is an enzyme (specifically, a family of isozymes) that is responsible for formation of prostanoids, including thromboxane and prostaglandins such as prostacyclin, from arachidonic acid.
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Cyclopentane
Cyclopentane is a highly flammable alicyclic hydrocarbon with chemical formula C5H10 and CAS number 287-92-3, consisting of a ring of five carbon atoms each bonded with two hydrogen atoms above and below the plane.
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CYP2E1
Cytochrome P450 2E1 (abbreviated CYP2E1) is a member of the cytochrome P450 mixed-function oxidase system, which is involved in the metabolism of xenobiotics in the body.
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Cytosol
The cytosol, also known as intracellular fluid (ICF) or cytoplasmic matrix, is the liquid found inside cells.
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Diglyceride
A diglyceride, or diacylglycerol (DAG), is a glyceride consisting of two fatty acid chains covalently bonded to a glycerol molecule through ester linkages.
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Dihydroxyacetone phosphate
Dihydroxyacetone phosphate (DHAP, also glycerone phosphate in older texts) is the anion with the formula HOCH2C(O)CH2OPO32-.
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Eicosanoid
Eicosanoids are signaling molecules made by the enzymatic or non-enzymatic oxidation of arachidonic acid or other polyunsaturated fatty acids (PUFAs) that are, similar to arachidonic acid, 20 carbon units in length.
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Emulsion
An emulsion is a mixture of two or more liquids that are normally immiscible (unmixable or unblendable).
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Endocrine system
The endocrine system is a chemical messenger system consisting of hormones, the group of glands of an organism that carry those hormones directly into the circulatory system to be carried towards distant target organs, and the feedback loops of homeostasis that the hormones drive.
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Endoplasmic reticulum
The endoplasmic reticulum (ER) is a type of organelle found in eukaryotic cells that forms an interconnected network of flattened, membrane-enclosed sacs or tube-like structures known as cisternae.
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Endothelium
Endothelium refers to cells that line the interior surface of blood vessels and lymphatic vessels, forming an interface between circulating blood or lymph in the lumen and the rest of the vessel wall.
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Enoyl-acyl carrier protein reductase
Enoyl-acyl carrier protein reductase (or ENR), is a key enzyme of the type II fatty acid synthesis (FAS) system.
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Enoyl-CoA hydratase
Enoyl-CoA hydratase is an enzyme that hydrates the double bond between the second and third carbons on acyl-CoA.
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Enterocyte
Enterocytes, or intestinal absorptive cells, are simple columnar epithelial cells found in the small intestine.
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Enzyme
Enzymes are macromolecular biological catalysts.
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Escherichia coli
Escherichia coli (also known as E. coli) is a Gram-negative, facultatively anaerobic, rod-shaped, coliform bacterium of the genus Escherichia that is commonly found in the lower intestine of warm-blooded organisms (endotherms).
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Essential fatty acid
Essential fatty acids, or EFAs, are fatty acids that humans and other animals must ingest because the body requires them for good health but cannot synthesize them.
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Extracellular fluid
Extracellular fluid (ECF) denotes all body fluid outside the cells.
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Fat
Fat is one of the three main macronutrients, along with carbohydrate and protein.
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Fatty acid
In chemistry, particularly in biochemistry, a fatty acid is a carboxylic acid with a long aliphatic chain, which is either saturated or unsaturated.
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Fatty acid synthase
Fatty acid synthase (FAS) is an enzyme that in humans is encoded by the FASN gene.
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Fatty acid synthesis
Fatty acid synthesis is the creation of fatty acids from acetyl-CoA and NADPH through the action of enzymes called fatty acid synthases.
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Fatty-acid metabolism disorder
A broad classification for genetic disorders that result from an inability of the body to produce or utilize one enzyme that is required to oxidize fatty acids.
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Flavin adenine dinucleotide
In biochemistry, flavin adenine dinucleotide (FAD) is a redox cofactor, more specifically a prosthetic group of a protein, involved in several important enzymatic reactions in metabolism.
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Formate
Formate (IUPAC name: methanoate) is the anion derived from formic acid.
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Gastrointestinal tract
The gastrointestinal tract (digestive tract, digestional tract, GI tract, GIT, gut, or alimentary canal) is an organ system within humans and other animals which takes in food, digests it to extract and absorb energy and nutrients, and expels the remaining waste as feces.
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Glucagon
Glucagon is a peptide hormone, produced by alpha cells of the pancreas.
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Gluconeogenesis
Gluconeogenesis (GNG) is a metabolic pathway that results in the generation of glucose from certain non-carbohydrate carbon substrates.
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Glucose
Glucose is a simple sugar with the molecular formula C6H12O6.
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Glyceraldehyde 3-phosphate
Glyceraldehyde 3-phosphate, also known as triose phosphate or 3-phosphoglyceraldehyde and abbreviated as G3P, GA3P, GADP, GAP, TP, GALP or PGAL, is the metabolite that occurs as an intermediate in several central pathways of all organisms.
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Glycerol
Glycerol (also called glycerine or glycerin; see spelling differences) is a simple polyol compound.
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Glycerol 3-phosphate
sn-Glycerol 3-phosphate is a phosphoric ester of glycerol, which is a component of glycerophospholipids.
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Glycerol kinase
Glycerol kinase, encoded by the gene GK, is a phosphotransferase enzyme involved in triglycerides and glycerophospholipids synthesis.
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Glycogen
Glycogen is a multibranched polysaccharide of glucose that serves as a form of energy storage in humans, animals, fungi, and bacteria.
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Glycolysis
Glycolysis (from glycose, an older term for glucose + -lysis degradation) is the metabolic pathway that converts glucose C6H12O6, into pyruvate, CH3COCOO− + H+.
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Golgi apparatus
The Golgi apparatus, also known as the Golgi complex, Golgi body, or simply the Golgi, is an organelle found in most eukaryotic cells.
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Gram
The gram (alternative spelling: gramme; SI unit symbol: g) (Latin gramma, from Greek γράμμα, grámma) is a metric system unit of mass.
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Guanosine triphosphate
Guanosine-5'-triphosphate (GTP) is a purine nucleoside triphosphate.
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Hibernation
Hibernation is a state of inactivity and metabolic depression in endotherms.
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Hormone
A hormone (from the Greek participle “ὁρμῶ”, "to set in motion, urge on") is any member of a class of signaling molecules produced by glands in multicellular organisms that are transported by the circulatory system to target distant organs to regulate physiology and behaviour.
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Hydrocarbon
In organic chemistry, a hydrocarbon is an organic compound consisting entirely of hydrogen and carbon.
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Hydrolysis
Hydrolysis is a term used for both an electro-chemical process and a biological one.
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Hydrophobe
In chemistry, hydrophobicity is the physical property of a molecule (known as a hydrophobe) that is seemingly repelled from a mass of water.
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Hydroxyacetone
Hydroxyacetone, also known as acetol, is an organic chemical consisting of a primary alcohol substituent on acetone.
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Hydroxyeicosatetraenoic acid
Hydroxyeicosatetraenoic acid may refer to.
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Hyperlipidemia
Hyperlipidemia is abnormally elevated levels of any or all lipids or lipoproteins in the blood.
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Hypertriglyceridemia
Hypertriglyceridemia denotes high (hyper-) blood levels (-emia) of triglycerides, the most abundant fatty molecule in most organisms.
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Inborn error of lipid metabolism
Numerous genetic disorders are caused by errors in fatty acid metabolism.
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Inborn errors of metabolism
Inborn errors of metabolism form a large class of genetic diseases involving congenital disorders of metabolism.
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Inflammation
Inflammation (from inflammatio) is part of the complex biological response of body tissues to harmful stimuli, such as pathogens, damaged cells, or irritants, and is a protective response involving immune cells, blood vessels, and molecular mediators.
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Inner mitochondrial membrane
The inner mitochondrial membrane (IMM) is the mitochondrial membrane which separates the mitochondrial matrix from the intermembrane space.
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Inositol trisphosphate
Inositol trisphosphate or inositol 1,4,5-trisphosphate (also commonly known as triphosphoinositol; abbreviated InsP3 or Ins3P or IP3), together with diacylglycerol (DAG), is a secondary messenger molecule used in signal transduction and lipid signaling in biological cells.
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Insulin
Insulin (from Latin insula, island) is a peptide hormone produced by beta cells of the pancreatic islets; it is considered to be the main anabolic hormone of the body.
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Intermediate-density lipoprotein
Intermediate-density lipoproteins (IDLs) belong to the lipoprotein particle family and are formed from the degradation of very low-density lipoproteins as well as high-density lipoproteins.
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Isocitrate dehydrogenase
Isocitrate dehydrogenase (IDH) and is an enzyme that catalyzes the oxidative decarboxylation of isocitrate, producing alpha-ketoglutarate (α-ketoglutarate) and CO2.
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Isotopic labeling
Isotopic labeling (or isotopic labelling) is a technique used to track the passage of an isotope (an atom with a detectable variation) through a reaction, metabolic pathway, or cell.
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Journal of Biological Chemistry
The Journal of Biological Chemistry is a weekly peer-reviewed scientific journal that was established in 1905.
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Ketoacidosis
Ketoacidosis is a metabolic state associated with high concentrations of ketone bodies, formed by the breakdown of fatty acids and the deamination of amino acids.
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Ketone bodies
Ketone bodies are three water-soluble molecules (acetoacetate, beta-hydroxybutyrate, and their spontaneous breakdown product, acetone) containing the ketone group that are produced by the liver from fatty acids during periods of low food intake (fasting), carbohydrate restrictive diets, starvation, prolonged intense exercise, alcoholism or in untreated (or inadequately treated) type 1 diabetes mellitus.
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Ketosis
Ketosis is a metabolic state in which some of the body's energy supply comes from ketone bodies in the blood, in contrast to a state of glycolysis in which blood glucose provides energy.
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Lactaldehyde
Lactaldehyde is an intermediate in the methylglyoxal metabolic pathway.
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Lacteal
A lacteal is a lymphatic capillary that absorbs dietary fats in the villi of the small intestine.
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Lactic acid
Lactic acid is an organic compound with the formula CH3CH(OH)COOH.
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Leukotriene
Leukotrienes are a family of eicosanoid inflammatory mediators produced in leukocytes by the oxidation of arachidonic acid (AA) and the essential fatty acid eicosapentaenoic acid (EPA) by the enzyme arachidonate 5-lipoxygenase.
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Lipase
A lipase is any enzyme that catalyzes the hydrolysis of fats (lipids).
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Lipid
In biology and biochemistry, a lipid is a biomolecule that is soluble in nonpolar solvents.
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Lipid bilayer
The lipid bilayer (or phospholipid bilayer) is a thin polar membrane made of two layers of lipid molecules.
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Lipid storage disorder
A lipid storage disorder (or lipidosis) can be any one of a group of inherited metabolic disorders in which harmful amounts of fats or lipids accumulate in some of the body’s cells and tissues.
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Lipogenesis
Lipogenesis is the process by which acetyl-CoA is converted to fatty acids.
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Lipolysis
Lipolysis is the breakdown of lipids and involves hydrolysis of triglycerides into glycerol and free fatty acids.
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Lipoprotein lipase
Lipoprotein lipase (LPL) is a member of the lipase gene family, which includes pancreatic lipase, hepatic lipase, and endothelial lipase.
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Lipoxygenase
Lipoxygenases are a family of (non-heme), iron-containing enzymes most of which catalyze the dioxygenation of polyunsaturated fatty acids in lipids containing a cis,cis-1,4- pentadiene into cell signaling agents that serve diverse roles as autocrine signals that regulate the function of their parent cells, paracrine signals that regulate the function of nearby cells, and endocrine signals that regulate the function of distant cells.
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Liver
The liver, an organ only found in vertebrates, detoxifies various metabolites, synthesizes proteins, and produces biochemicals necessary for digestion.
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Long-chain-fatty-acid—CoA ligase
The long chain fatty acyl-CoA ligase (or synthetase) is an enzyme of the ligase family that activates the breakdown of complex fatty acids.
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Low-density lipoprotein
Low-density lipoprotein (LDL) is one of the five major groups of lipoprotein which transport all fat molecules around the body in the extracellular water.
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Lymphatic system
The lymphatic system is part of the vascular system and an important part of the immune system, comprising a network of lymphatic vessels that carry a clear fluid called lymph (from Latin, lympha meaning "water") directionally towards the heart.
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Malic acid
Malic acid is an organic compound with the molecular formula C4H6O5.
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Malonyl-CoA
Malonyl-CoA is a coenzyme A derivative of malonic acid.
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Mammary gland
A mammary gland is an exocrine gland in mammals that produces milk to feed young offspring.
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Methylglyoxal
Methylglyoxal, also called pyruvaldehyde or 2-oxopropanal, is the organic compound with the formula CH3C(O)CHO.
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Micelle
A micelle or micella (plural micelles or micellae, respectively) is an aggregate (or supramolecular assembly) of surfactant molecules dispersed in a liquid colloid.
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Mitochondrion
The mitochondrion (plural mitochondria) is a double-membrane-bound organelle found in most eukaryotic organisms.
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Molecule
A molecule is an electrically neutral group of two or more atoms held together by chemical bonds.
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Monoglyceride
Monoglycerides (also: acylglycerols or monoacylglycerols) are a class of glycerides which are composed of a molecule of glycerol linked to a fatty acid via an ester bond.
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Neuron
A neuron, also known as a neurone (British spelling) and nerve cell, is an electrically excitable cell that receives, processes, and transmits information through electrical and chemical signals.
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Nicotinamide adenine dinucleotide
Nicotinamide adenine dinucleotide (NAD) is a coenzyme found in all living cells.
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Nicotinamide adenine dinucleotide phosphate
Nicotinamide adenine dinucleotide phosphate, abbreviated NADP or, in older notation, TPN (triphosphopyridine nucleotide), is a cofactor used in anabolic reactions, such as lipid and nucleic acid synthesis, which require NADPH as a reducing agent.
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Norepinephrine
Norepinephrine (NE), also called noradrenaline (NA) or noradrenalin, is an organic chemical in the catecholamine family that functions in the brain and body as a hormone and neurotransmitter.
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Nucleic acid
Nucleic acids are biopolymers, or small biomolecules, essential to all known forms of life.
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Nucleotide
Nucleotides are organic molecules that serve as the monomer units for forming the nucleic acid polymers deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), both of which are essential biomolecules within all life-forms on Earth.
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Nutrient
A nutrient is a substance used by an organism to survive, grow, and reproduce.
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Oleic acid
Oleic acid is a fatty acid that occurs naturally in various animal and vegetable fats and oils.
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Organelle
In cell biology, an organelle is a specialized subunit within a cell that has a specific function, in which their function is vital for the cell to live.
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Oxaloacetic acid
Oxaloacetic acid (also known as oxalacetic acid) is a crystalline organic compound with the chemical formula HO2CC(O)CH2CO2H.
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Oxoglutarate dehydrogenase complex
The oxoglutarate dehydrogenase complex (OGDC) or α-ketoglutarate dehydrogenase complex is an enzyme complex, most commonly known for its role in the citric acid cycle.
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Palmitic acid
Palmitic acid, or hexadecanoic acid in IUPAC nomenclature, is the most common saturated fatty acid found in animals, plants and microorganisms.
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Pancreatic lipase family
Triglyceride lipases are a family of lipolytic enzymes that hydrolyse ester linkages of triglycerides.
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Paracrine signalling
Paracrine signaling is a form of cell-to-cell communication in which a cell produces a signal to induce changes in nearby cells, altering the behavior of those cells.
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Pentose phosphate pathway
The pentose phosphate pathway (also called the phosphogluconate pathway and the hexose monophosphate shunt) is a metabolic pathway parallel to glycolysis.
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Phosphatidic acid
Phosphatidic acids are phospholipids which on hydrolysis give rise to one molecule of glycerol and phosphoric acid and two molecules of fatty acids.
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Phosphatidylinositol 4,5-bisphosphate
Phosphatidylinositol 4,5-bisphosphate or PtdIns(4,5)P2, also known simply as PIP2 or PI(4,5)P2, is a minor phospholipid component of cell membranes.
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Phospholipase A2
Phospholipases A2 (PLA2s) are enzymes that release fatty acids from the second carbon group of glycerol.
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Phospholipase C
Phospholipase C (PLC) is a class of membrane-associated enzymes that cleave phospholipids just before the phosphate group (see figure).
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Phospholipid
Phospholipids are a class of lipids that are a major component of all cell membranes.
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Phosphorylation
In chemistry, phosphorylation of a molecule is the attachment of a phosphoryl group.
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Physiology
Physiology is the scientific study of normal mechanisms, and their interactions, which work within a living system.
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Platelet
Platelets, also called thrombocytes (from Greek θρόμβος, "clot" and κύτος, "cell"), are a component of blood whose function (along with the coagulation factors) is to react to bleeding from blood vessel injury by clumping, thereby initiating a blood clot.
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Portal vein
The portal vein or hepatic portal vein is a blood vessel that carries blood from the gastrointestinal tract, gallbladder, pancreas and spleen to the liver.
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Pound (mass)
The pound or pound-mass is a unit of mass used in the imperial, United States customary and other systems of measurement.
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Prokaryote
A prokaryote is a unicellular organism that lacks a membrane-bound nucleus, mitochondria, or any other membrane-bound organelle.
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Prolactin
Prolactin (PRL), also known as luteotropic hormone or luteotropin, is a protein that is best known for its role in enabling mammals, usually females, to produce milk.
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Propionaldehyde
Propionaldehyde or propanal is the organic compound with the formula CH3CH2CHO.
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Propionyl-CoA
Propionyl-CoA is a coenzyme A derivative of propionic acid.
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Propylene glycol
Propylene glycol (IUPAC name: propane-1,2-diol) is a synthetic organic compound with the chemical formula C3H8O2.
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Prostacyclin
Prostacyclin (also called prostaglandin I2 or PGI2) is a prostaglandin member of the eicosanoid family of lipid molecules.
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Prostaglandin
The prostaglandins (PG) are a group of physiologically active lipid compounds having diverse hormone-like effects in animals.
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Prostanoid
Prostanoids are a subclass of eicosanoids consisting of the prostaglandins (mediators of inflammatory and anaphylactic reactions), the thromboxanes (mediators of vasoconstriction), and the prostacyclins (active in the resolution phase of inflammation.).
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Protein kinase C
Protein kinase C, commonly abbreviated to PKC (EC 2.7.11.13), is a family of protein kinase enzymes that are involved in controlling the function of other proteins through the phosphorylation of hydroxyl groups of serine and threonine amino acid residues on these proteins, or a member of this family.
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Pyruvate dehydrogenase complex
Pyruvate dehydrogenase complex (PDC) is a complex of three enzymes that converts pyruvate into acetyl-CoA by a process called pyruvate decarboxylation.
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Pyruvic acid
Pyruvic acid (CH3COCOOH) is the simplest of the alpha-keto acids, with a carboxylic acid and a ketone functional group.
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Receptor (biochemistry)
In biochemistry and pharmacology, a receptor is a protein molecule that receives chemical signals from outside a cell.
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Red blood cell
Red blood cells-- also known as RBCs, red cells, red blood corpuscles, haematids, erythroid cells or erythrocytes (from Greek erythros for "red" and kytos for "hollow vessel", with -cyte translated as "cell" in modern usage), are the most common type of blood cell and the vertebrate's principal means of delivering oxygen (O2) to the body tissues—via blood flow through the circulatory system.
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Redox
Redox (short for reduction–oxidation reaction) (pronunciation: or) is a chemical reaction in which the oxidation states of atoms are changed.
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Second messenger system
Second messengers are intracellular signaling molecules released by the cell in response to exposure to extracellular signaling molecules—the first messengers.
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Secretion
Secretion is the movement of material from one point to another, e.g. secreted chemical substance from a cell or gland.
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Serine
Serine (symbol Ser or S) is an ɑ-amino acid that is used in the biosynthesis of proteins.
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SLCO2A1
Solute carrier organic anion transporter family, member 2A1 also known as the prostaglandin transporter (PGT) is a protein that in humans is encoded by the SLCO2A1 gene.
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Smooth muscle tissue
Smooth muscle is an involuntary non-striated muscle.
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Solute carrier family
The solute carrier (SLC) group of membrane transport proteins include over 400 members organized into 65 families.
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Steroid hormone
A steroid hormone is a steroid that acts as a hormone.
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Sympathetic nervous system
The sympathetic nervous system (SNS) is one of the two main divisions of the autonomic nervous system, the other being the parasympathetic nervous system.
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Thiolase
Thiolases, also known as acetyl-coenzyme A acetyltransferases (ACAT), are enzymes which convert two units of acetyl-CoA to acetoacetyl CoA in the mevalonate pathway.
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Thoracic duct
In human anatomy, the thoracic duct is the larger of the two lymph ducts of the lymphatic system.
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Threonine
Threonine (symbol Thr or T) is an amino acid that is used in the biosynthesis of proteins.
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Thrombosis
Thrombosis (from Ancient Greek θρόμβωσις thrómbōsis "clotting”) is the formation of a blood clot inside a blood vessel, obstructing the flow of blood through the circulatory system.
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Thromboxane
Thromboxane is a member of the family of lipids known as eicosanoids.
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Tissue (biology)
In biology, tissue is a cellular organizational level between cells and a complete organ.
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Transport protein
A transport protein (variously referred to as a transmembrane pump, transporter, escort protein, acid transport protein, cation transport protein, or anion transport protein) is a protein that serves the function of moving other materials within an organism.
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Triglyceride
A triglyceride (TG, triacylglycerol, TAG, or triacylglyceride) is an ester derived from glycerol and three fatty acids (from tri- and glyceride).
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Triosephosphate isomerase
Triose-phosphate isomerase (TPI or TIM) is an enzyme that catalyzes the reversible interconversion of the triose phosphate isomers dihydroxyacetone phosphate and D-glyceraldehyde 3-phosphate.
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Vasoconstriction
Vasoconstriction is the narrowing of the blood vessels resulting from contraction of the muscular wall of the vessels, in particular the large arteries and small arterioles.
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Vasodilation
Vasodilation is the widening of blood vessels.
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Very low-density lipoprotein
Very-low-density lipoprotein (VLDL), density relative to extracellular water, is a type of lipoprotein made by the liver.
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Water
Water is a transparent, tasteless, odorless, and nearly colorless chemical substance that is the main constituent of Earth's streams, lakes, and oceans, and the fluids of most living organisms.
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(acyl-carrier-protein) S-acetyltransferase
In enzymology, a S-acetyltransferase is an enzyme that catalyzes the chemical reaction Thus, the two substrates of this enzyme are acetyl-CoA and acyl carrier protein, whereas its two products are CoA and acetyl-acyl-carrier-protein.
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(acyl-carrier-protein) S-malonyltransferase
In enzymology, a S-malonyltransferase is an enzyme that catalyzes the chemical reaction Thus, the two substrates of this enzyme are malonyl-CoA and acyl carrier protein, whereas its two products are CoA and malonyl-acyl-carrier-protein.
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3-Hydroxyacyl ACP dehydrase
3-Hydroxyacyl ACP dehydrase is an enzyme involved in fatty acid synthesis.
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3-hydroxyacyl-CoA dehydrogenase
In enzymology, a 3-hydroxyacyl-CoA dehydrogenase is an enzyme that catalyzes the chemical reaction Thus, the two substrates of this enzyme are (S)-3-hydroxyacyl-CoA and NAD+, whereas its 3 products are 3-oxoacyl-CoA, NADH, and H+.
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3-oxoacyl-(acyl-carrier-protein) reductase
In enzymology, a 3-oxoacyl- reductase is an enzyme that catalyzes the chemical reaction Thus, the two substrates of this enzyme are (3R)-3-hydroxyacyl-acyl-carrier-protein and NADP+, whereas its 3 products are 3-oxoacyl-acyl-carrier-protein, NADPH, and H+.
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Fat anabolism, Fat catabolism, Fatty-acid metabolism, Lipid anabolism, Lipid catabolism, Lipoid metabolism.
References
[1] https://en.wikipedia.org/wiki/Fatty_acid_metabolism