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Carboxybenzyl (abbreviated as Cbz or Z) is a carbamate which is often used as an amine protecting group in organic synthesis. [1]

16 relations: Amine, Benzyl alcohol, Benzyl chloroformate, Carbamate, Carbamic acid, Chemische Berichte, Curtius rearrangement, Electrophile, Hydrogen bromide, Hydrogenation, Isocyanate, Max Bergmann, Organic synthesis, Peptide synthesis, Protecting group, Weak base.


Amines (US: or, UK:, or) are organic compounds and functional groups that contain a basic nitrogen atom with a lone pair.

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Benzyl alcohol

Benzyl alcohol is an aromatic alcohol with the formula C6H5CH2OH.

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Benzyl chloroformate

Benzyl chloroformate is the benzyl ester of chloroformic acid.

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A carbamate is an organic compound derived from carbamic acid (NH2COOH).

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Carbamic acid

Carbamic acid is the compound with the formula H2NCO2H.

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Chemische Berichte

Until 1998, Chemische Berichte (usually abbreviated as Ber. or Chem. Ber.) was a German-language scientific journal featuring chemistry of all disciplines.

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Curtius rearrangement

The Curtius rearrangement (or Curtius reaction or Curtius degradation), as first defined by Theodor Curtius, is a chemical reaction that involves the rearrangement of an acyl azide to an isocyanate.

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In chemistry, an electrophile (literally electron lover) is a reagent attracted to electrons.

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Hydrogen bromide

Hydrogen bromide is the diatomic molecule with the formula HBr.

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Hydrogenation – to treat with hydrogen – is a chemical reaction between molecular hydrogen (H2) and another compound or element, usually in the presence of a catalyst such as nickel, palladium or platinum.

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Isocyanate is the functional group with the formula R–N.

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Max Bergmann

Max Bergmann (1886–1944) was a Jewish-German biochemist.

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Organic synthesis

Organic synthesis is a special branch of chemical synthesis and is concerned with the construction of organic compounds via organic reactions.

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Peptide synthesis

In organic chemistry, peptide synthesis is the production of peptides, which are organic compounds in which multiple amino acids are linked via amide bonds, also known as peptide bonds.

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Protecting group

A protecting group or protective group is introduced into a molecule by chemical modification of a functional group to obtain chemoselectivity in a subsequent chemical reaction.

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Weak base

In chemistry, a weak base is a chemical base that does not ionize fully in an aqueous solution.

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Redirects here:

Benzyl carbamate, Bergmann-Zervas carbobenzoxy method, Bergmann–Zervas carbobenzoxy method, Carbobenzoxy method, Z group.


[1] https://en.wikipedia.org/wiki/Carboxybenzyl

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