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91 relations: Adipogenesis, Alanine, Alternative splicing, Amino acid, Apoptosis, Arginine, ARNTL, Asthma, Base pair, Basic helix-loop-helix, BHLHB2, Biodegradation, Breast cancer, C-terminus, CDNA library, Cell nucleus, Chemotherapy, Chromosome 12, Circadian clock, Circadian rhythm, CLOCK, Colorectal cancer, Competitive inhibition, CYP2D6, DNA, E-box, EHMT2, Embryogenesis, EPAS1, Epithelial–mesenchymal transition, Exon, Expressed sequence tag, GATA3, Gene, Gene regulatory network, Glycine, Hepatocellular carcinoma, HIF1A, Histone deacetylase, Histone methylation, Histone methyltransferase, Homeostasis, Homology (biology), Humoral immunity, Hypoxia (medical), IL-2 receptor, IL2RA, In vivo, Inflammation, Insulin-like growth factor 2, ..., Intron, Knockout mouse, Memory consolidation, Metastasis, Mitochondrion, Muscle contraction, MyoD, Myogenesis, National Center for Biotechnology Information, Negative feedback, Non-rapid eye movement sleep, Oral cancer, Ovalbumin, PER2, Period (gene), Point mutation, Proline, Promoter (genetics), Proteasome, Protein dimer, Protein methylation, Rapid eye movement sleep, Regulator gene, Repressor, Sarcoma, Senescence, Sequence homology, Skeletal muscle, STAT6, Sterol regulatory element-binding protein 1, SUMO protein, Suprachiasmatic nucleus, T cell, T helper cell, TCF3, Transcription (biology), Transcription factor, Triple-negative breast cancer, Vascular endothelial growth factor, Weizmann Institute of Science, Ying-Hui Fu. Expand index (41 more) »
Adipogenesis
Adipogenesis is the process of cell differentiation by which pre-adipocytes become adipocytes.
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Alanine
Alanine (symbol Ala or A) is an α-amino acid that is used in the biosynthesis of proteins.
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Alternative splicing
Alternative splicing, or differential splicing, is a regulated process during gene expression that results in a single gene coding for multiple proteins.
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Amino acid
Amino acids are organic compounds containing amine (-NH2) and carboxyl (-COOH) functional groups, along with a side chain (R group) specific to each amino acid.
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Apoptosis
Apoptosis (from Ancient Greek ἀπόπτωσις "falling off") is a process of programmed cell death that occurs in multicellular organisms.
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Arginine
Arginine (symbol Arg or R) is an α-amino acid that is used in the biosynthesis of proteins.
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ARNTL
Aryl hydrocarbon receptor nuclear translocator-like protein 1 is protein that in humans is encoded by the ARNTL gene, also known as BMAL1, MOP3, and, less commonly, BHLHE5, BMAL, BMAL1C, JAP3, PASD3, and TIC.
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Asthma
Asthma is a common long-term inflammatory disease of the airways of the lungs.
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Base pair
A base pair (bp) is a unit consisting of two nucleobases bound to each other by hydrogen bonds.
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Basic helix-loop-helix
A basic helix-loop-helix (bHLH) is a protein structural motif that characterizes one of the largest families of dimerizing transcription factors.
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BHLHB2
Class E basic helix-loop-helix protein 40 is a protein that in humans is encoded by the BHLHE40 gene.
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Biodegradation
Biodegradation is the disintegration of materials by bacteria, fungi, or other biological means.
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Breast cancer
Breast cancer is cancer that develops from breast tissue.
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C-terminus
The C-terminus (also known as the carboxyl-terminus, carboxy-terminus, C-terminal tail, C-terminal end, or COOH-terminus) is the end of an amino acid chain (protein or polypeptide), terminated by a free carboxyl group (-COOH).
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CDNA library
A cDNA library is a combination of cloned cDNA (complementary DNA) fragments inserted into a collection of host cells, which together constitute some portion of the transcriptome of the organism and are stored as a "library".
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Cell nucleus
In cell biology, the nucleus (pl. nuclei; from Latin nucleus or nuculeus, meaning kernel or seed) is a membrane-enclosed organelle found in eukaryotic cells.
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Chemotherapy
Chemotherapy (often abbreviated to chemo and sometimes CTX or CTx) is a type of cancer treatment that uses one or more anti-cancer drugs (chemotherapeutic agents) as part of a standardized chemotherapy regimen.
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Chromosome 12
Chromosome 12 is one of the 23 pairs of chromosomes in humans.
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Circadian clock
A circadian clock, or circadian oscillator, is a biochemical oscillator that cycles with a stable phase and is synchronized with solar time.
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Circadian rhythm
A circadian rhythm is any biological process that displays an endogenous, entrainable oscillation of about 24 hours.
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CLOCK
Clock (Circadian Locomotor Output Cycles Kaput) is a gene encoding a basic helix-loop-helix-PAS transcription factor (CLOCK) that is believed to affect both the persistence and period of circadian rhythms.
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Colorectal cancer
Colorectal cancer (CRC), also known as bowel cancer and colon cancer, is the development of cancer from the colon or rectum (parts of the large intestine).
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Competitive inhibition
Competitive inhibition is a form of enzyme inhibition where binding of an inhibitor prevents binding of the target molecule of the enzyme, also known as the substrate.
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CYP2D6
Cytochrome P450 2D6 (CYP2D6) is an enzyme that in humans is encoded by the CYP2D6 gene.
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DNA
Deoxyribonucleic acid (DNA) is a thread-like chain of nucleotides carrying the genetic instructions used in the growth, development, functioning and reproduction of all known living organisms and many viruses.
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E-box
An E-box (enhancer box) is a DNA response element found in some eukaryotes that acts as a protein-binding site and has been found to regulate gene expression in neurons, muscles, and other tissues.
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EHMT2
Euchromatic histone-lysine N-methyltransferase 2 (EHMT2), also known as G9a, is a histone methyltransferase that in humans is encoded by the EHMT2 gene.
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Embryogenesis
Embryogenesis is the process by which the embryo forms and develops.
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EPAS1
Endothelial PAS domain-containing protein 1 (EPAS1, also known as hypoxia-inducible factor-2alpha (HIF-2alpha)) is a protein that in humans is encoded by the EPAS1 gene.
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Epithelial–mesenchymal transition
The epithelial–mesenchymal transition (EMT) is a process by which epithelial cells lose their cell polarity and cell-cell adhesion, and gain migratory and invasive properties to become mesenchymal stem cells; these are multipotent stromal cells that can differentiate into a variety of cell types.
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Exon
An exon is any part of a gene that will encode a part of the final mature RNA produced by that gene after introns have been removed by RNA splicing.
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Expressed sequence tag
In genetics, an expressed sequence tag (EST) is a short sub-sequence of a cDNA sequence.
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GATA3
GATA3 is a transcription factor that in humans is encoded by the GATA3 gene.
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Gene
In biology, a gene is a sequence of DNA or RNA that codes for a molecule that has a function.
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Gene regulatory network
A gene (or genetic) regulatory network (GRN) is a collection of molecular regulators that interact with each other and with other substances in the cell to govern the gene expression levels of mRNA and proteins.
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Glycine
Glycine (symbol Gly or G) is the amino acid that has a single hydrogen atom as its side chain.
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Hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer in adults, and is the most common cause of death in people with cirrhosis.
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HIF1A
Hypoxia-inducible factor 1-alpha, also known as HIF-1-alpha, is a subunit of a heterodimeric transcription factor hypoxia-inducible factor 1 (HIF-1) that is encoded by the HIF1A gene.
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Histone deacetylase
Histone deacetylases (HDAC) are a class of enzymes that remove acetyl groups (O.
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Histone methylation
Histone methylation is a process by which methyl groups are transferred to amino acids of histone proteins that make up nucleosomes, which the DNA double helix wraps around to form chromosomes.
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Histone methyltransferase
Histone methyltransferases (HMT) are histone-modifying enzymes (e.g., histone-lysine N-methyltransferases and histone-arginine N-methyltransferases), that catalyze the transfer of one, two, or three methyl groups to lysine and arginine residues of histone proteins.
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Homeostasis
Homeostasis is the tendency of organisms to auto-regulate and maintain their internal environment in a stable state.
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Homology (biology)
In biology, homology is the existence of shared ancestry between a pair of structures, or genes, in different taxa.
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Humoral immunity
Humoral immunity or humoural immunity is the aspect of immunity that is mediated by macromolecules found in extracellular fluids such as secreted antibodies, complement proteins, and certain antimicrobial peptides.
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Hypoxia (medical)
Hypoxia is a condition in which the body or a region of the body is deprived of adequate oxygen supply at the tissue level.
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IL-2 receptor
The interleukin-2 receptor (IL-2R) is a heterotrimeric protein expressed on the surface of certain immune cells, such as lymphocytes, that binds and responds to a cytokine called IL-2.
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IL2RA
Interleukin-2 receptor alpha chain (also called CD25) is a protein that in humans is encoded by the IL2RA gene.
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In vivo
Studies that are in vivo (Latin for "within the living"; often not italicized in English) are those in which the effects of various biological entities are tested on whole, living organisms or cells, usually animals, including humans, and plants, as opposed to a tissue extract or dead organism.
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Inflammation
Inflammation (from inflammatio) is part of the complex biological response of body tissues to harmful stimuli, such as pathogens, damaged cells, or irritants, and is a protective response involving immune cells, blood vessels, and molecular mediators.
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Insulin-like growth factor 2
Insulin-like growth factor 2 (IGF-2) is one of three protein hormones that share structural similarity to insulin.
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Intron
An intron is any nucleotide sequence within a gene that is removed by RNA splicing during maturation of the final RNA product.
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Knockout mouse
A knockout mouse or knock-out mouse is a genetically modified mouse (Mus musculus) in which researchers have inactivated, or "knocked out", an existing gene by replacing it or disrupting it with an artificial piece of DNA.
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Memory consolidation
Memory consolidation is a category of processes that stabilize a memory trace after its initial acquisition.
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Metastasis
Metastasis is a pathogenic agent's spread from an initial or primary site to a different or secondary site within the host's body; it is typically spoken of as such spread by a cancerous tumor.
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Mitochondrion
The mitochondrion (plural mitochondria) is a double-membrane-bound organelle found in most eukaryotic organisms.
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Muscle contraction
Muscle contraction is the activation of tension-generating sites within muscle fibers.
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MyoD
MyoD is a protein that plays a major role in regulating muscle differentiation.
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Myogenesis
Myogenesis is the formation of muscular tissue, particularly during embryonic development.
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National Center for Biotechnology Information
The National Center for Biotechnology Information (NCBI) is part of the United States National Library of Medicine (NLM), a branch of the National Institutes of Health (NIH).
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Negative feedback
Negative feedback (or balancing feedback) occurs when some function of the output of a system, process, or mechanism is fed back in a manner that tends to reduce the fluctuations in the output, whether caused by changes in the input or by other disturbances.
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Non-rapid eye movement sleep
Non-rapid eye movement sleep (NREM) is, collectively, sleep stages 1–3, previously known as stages 1–4.
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Oral cancer
Oral cancer, also known as mouth cancer, is a type of head and neck cancer and is any cancerous tissue growth located in the oral cavity.
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Ovalbumin
Ovalbumin (abbreviated OVA) is the main protein found in egg white, making up approximately 55% of the total protein.
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PER2
PER2 is a protein in mammals encoded by the PER2 gene.
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Period (gene)
Period (per) is a gene located on the X chromosome of Drosophila melanogaster.
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Point mutation
A point mutation is a genetic mutation where a single nucleotide base is changed, inserted or deleted from a sequence of DNA or RNA.
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Proline
Proline (symbol Pro or P) is a proteinogenic amino acid that is used in the biosynthesis of proteins.
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Promoter (genetics)
In genetics, a promoter is a region of DNA that initiates transcription of a particular gene.
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Proteasome
Proteasomes are protein complexes which degrade unneeded or damaged proteins by proteolysis, a chemical reaction that breaks peptide bonds.
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Protein dimer
In biochemistry, a protein dimer is a macromolecular complex formed by two protein monomers, or single proteins, which are usually non-covalently bound.
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Protein methylation
Protein methylation is the process through which a group of specific enzymes, the methyltransferases modify proteins by adding a methyl groups.
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Rapid eye movement sleep
Rapid eye movement sleep (REM sleep, REMS) is a unique phase of sleep in mammals and birds, distinguishable by random/rapid movement of the eyes, accompanied with low muscle tone throughout the body, and the propensity of the sleeper to dream vividly.
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Regulator gene
A regulator gene, regulator, or regulatory gene is a gene involved in controlling the expression of one or more other genes.
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Repressor
In molecular genetics, a repressor is a DNA- or RNA-binding protein that inhibits the expression of one or more genes by binding to the operator or associated silencers.
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Sarcoma
A sarcoma is a cancer that arises from transformed cells of mesenchymal origin.
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Senescence
Senescence or biological ageing is the gradual deterioration of function characteristic of most complex lifeforms, arguably found in all biological kingdoms, that on the level of the organism increases mortality after maturation.
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Sequence homology
Sequence homology is the biological homology between DNA, RNA, or protein sequences, defined in terms of shared ancestry in the evolutionary history of life.
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Skeletal muscle
Skeletal muscle is one of three major muscle types, the others being cardiac muscle and smooth muscle.
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STAT6
Signal transducer and activator of transcription 6 (STAT6) is a human gene.
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Sterol regulatory element-binding protein 1
Sterol regulatory element-binding transcription factor 1 (SREBF1) also known as sterol regulatory element-binding protein 1 (SREBP-1) is a protein that in humans is encoded by the SREBF1 gene.
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SUMO protein
Small Ubiquitin-like Modifier (or SUMO) proteins are a family of small proteins that are covalently attached to and detached from other proteins in cells to modify their function.
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Suprachiasmatic nucleus
The suprachiasmatic nucleus or nuclei (SCN) is a tiny region of the brain in the hypothalamus, situated directly above the optic chiasm.
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T cell
A T cell, or T lymphocyte, is a type of lymphocyte (a subtype of white blood cell) that plays a central role in cell-mediated immunity.
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T helper cell
The T helper cells (Th cells) are a type of T cell that play an important role in the immune system, particularly in the adaptive immune system.
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TCF3
Transcription factor 3 (E2A immunoglobulin enhancer-binding factors E12/E47), also known as TCF3, is a protein that in humans is encoded by the TCF3 gene.
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Transcription (biology)
Transcription is the first step of gene expression, in which a particular segment of DNA is copied into RNA (especially mRNA) by the enzyme RNA polymerase.
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Transcription factor
In molecular biology, a transcription factor (TF) (or sequence-specific DNA-binding factor) is a protein that controls the rate of transcription of genetic information from DNA to messenger RNA, by binding to a specific DNA sequence.
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Triple-negative breast cancer
Triple-negative breast cancer (sometimes abbreviated TNBC) refers to any breast cancer that does not express the genes for estrogen receptor (ER), progesterone receptor (PR) and Her2/neu.
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Vascular endothelial growth factor
Vascular endothelial growth factor (VEGF), originally known as vascular permeability factor (VPF), is a signal protein produced by cells that stimulates the formation of blood vessels.
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Weizmann Institute of Science
The Weizmann Institute of Science (מכון ויצמן למדע Machon Weizmann LeMada) is a public research university in Rehovot, Israel, established in 1934, 14 years before the State of Israel.
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Ying-Hui Fu
Ying-Hui Fu (傅嫈惠) is a biologist and human geneticist.
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Redirects here:
BHLHB3, BHLHE41 (gene), DEC2, HDEC2, SHARP1.
References
[1] https://en.wikipedia.org/wiki/BHLHE41
