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Health effects of tobacco

Index Health effects of tobacco

Tobacco use has predominantly negative effects on human health and concern about health effects of tobacco has a long history. [1]

259 relations: Abdomen, Abdominal aortic aneurysm, Acetaldehyde, Acrolein, Addiction, Adduct, Adolescence, Adrenaline, Adrenocortical carcinoma, Aflatoxin, Alertness, Alton Ochsner, Alzheimer's disease, American Cancer Society, American Lung Association, American Psychologist, Amitriptyline, Angiogenesis, Animal testing, Animal testing on rodents, Aorta, Aortic aneurysm, Apoptosis, Arteriosclerosis, Associated Press, Asthma, Atherosclerosis, Austin Bradford Hill, AZGP1, Bad breath, BBC, Becquerel, Beedi, Benzopyrene, Bladder cancer, Blood pressure, Blood vessel, Breast cancer, British Doctors Study, Bronchus, C. Everett Koop, CA (journal), Caffeine, Calmness, Cancer, Cannabis (drug), Carbon monoxide, Carbon monoxide poisoning, Carcinoembryonic antigen, Carcinogen, ..., Cardiovascular disease, Centers for Disease Control and Prevention, Cervical cancer, Chemical reaction, Chewing tobacco, Chronic kidney disease, Chronic obstructive pulmonary disease, Cigar, Cigarette, Cocaine, Colorectal cancer, Concentration, Confidence interval, Cotinine, Crohn's disease, Crotonaldehyde, Curie, Cyanide, Cytochrome P450, Developed country, Developing country, Diabetic nephropathy, Dizziness, DNA, Dopamine, Dopaminergic, Dresden, Drug tolerance, E. Cuyler Hammond, Edward Martell, Electrophile, Endometriosis, Endometrium, Endothelium, Epidemiology, Epithelium, Epoxide, Erectile dysfunction, Esophageal cancer, Estrogen, Ethanol, Expert Review of Cardiovascular Therapy, Fatty acid, Female infertility, Fetus, Fibrinogen, Folliculogenesis, Fritz Lickint, Gallbladder cancer, Germany, Gideon Lincecum, Gingival recession, Guanine, Harmane, Head and neck cancer, Hemiaminal, Heroin, High-density lipoprotein, HIV, Hookah, Hormone, Human musculoskeletal system, Hydrophobe, Hypercholesterolemia, Hypertension, In vitro fertilisation, International Agency for Research on Cancer, IRIN, Irving Fisher, Isotopes of lead, Isotopes of polonium, James A. Schoenberger, Johns Hopkins University, Journal of Periodontology, Journal of the National Cancer Institute, Judgement, Kaposi's sarcoma, Kidney, Kidney cancer, Language, Laryngeal cancer, Larynx, Lesion, Leukoplakia, Lipolysis, List of cigarette smoke carcinogens, Liver cancer, Logarithm, Longitudinal study, Low birth weight, Low-density lipoprotein, Lung cancer, Major depressive disorder, Mayo Clinic, McGill University, Memorial Sloan Kettering Cancer Center, Merchants of Doubt, Michael reaction, Miscarriage, Monoamine oxidase B, Monoamine oxidase inhibitor, Motor skill, Mouth, Mutagen, Mutation, Myeloid leukemia, Myocardial infarction, Myometrium, National Cancer Institute, National Center for Atmospheric Research, National Institutes of Health, Nausea, Neural tube defect, New York City, Nicotine, Nicotine gum, Nicotine patch, Nicotine withdrawal, Nitrosamine, NNK, Nucleophilic conjugate addition, Oncogene, Oral cancer, Ovary, Ovulation, Oxygen, Pakistan, Pancreatic cancer, Parkinson's disease, Passive smoking, Pediatrics (journal), Periodontal disease, Periodontology, Peripheral artery disease, Peter Jennings, Philip Morris International, Platelet, Pneumonia, Polycyclic aromatic hydrocarbon, Pregnancy, Preterm birth, Preventable causes of death, Programmed cell death, Psychoactive drug, Psychology, Pulmonary alveolus, Pyrolysis, Radioactive decay, Radiochemistry, Raven's Progressive Matrices, Reader's Digest, Recreational drug use, Relaxation (psychology), Respiratory system, Respiratory tract infection, Reuters, Richard Doll, Richard Peto, Risk, Risk factor, Schizophrenia, Schizophrenia and smoking, Sensitization, Sievert, Small intestine cancer, Small-cell carcinoma, Smoking and Health: Report of the Advisory Committee to the Surgeon General of the United States, Smoking and pregnancy, Smoking ban, Smoking cessation, Snuff (tobacco), Sputum, Squamous cell carcinoma, Stimulant, Stochastic, Stomach cancer, Streptococcus pneumoniae, Stroke, Sudden infant death syndrome, Sulfur mustard, Surgeon General of the United States, Tachycardia, Tar (tobacco residue), The Australian, The BMJ, The Independent Florida Alligator, Third-hand smoke, Throat, Thromboangiitis obliterans, Titration, Tobacco, Tobacco control, Tobacco packaging warning messages, Tobacco pipe, Tobacco smoking, Toxication, Tumor suppressor, United States Army, USA Today, Uterine fibroid, Uterus, Valproate, Vaporizer (inhalation device), Vitamin C, Wide-body aircraft, World Health Organization, World War I, Xerostomia, 1950 Wynder and Graham Study. Expand index (209 more) »

Abdomen

The abdomen (less formally called the belly, stomach, tummy or midriff) constitutes the part of the body between the thorax (chest) and pelvis, in humans and in other vertebrates.

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Abdominal aortic aneurysm

Abdominal aortic aneurysm (AAA or triple A) is a localized enlargement of the abdominal aorta such that the diameter is greater than 3 cm or more than 50% larger than normal diameter.

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Acetaldehyde

Acetaldehyde (systematic name ethanal) is an organic chemical compound with the formula CH3CHO, sometimes abbreviated by chemists as MeCHO (Me.

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Acrolein

Acrolein (systematic name: propenal) is the simplest unsaturated aldehyde.

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Addiction

Addiction is a brain disorder characterized by compulsive engagement in rewarding stimuli despite adverse consequences.

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Adduct

An adduct (from the Latin adductus, "drawn toward" alternatively, a contraction of "addition product") is a product of a direct addition of two or more distinct molecules, resulting in a single reaction product containing all atoms of all components.

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Adolescence

AdolescenceMacmillan Dictionary for Students Macmillan, Pan Ltd.

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Adrenaline

Adrenaline, also known as adrenalin or epinephrine, is a hormone, neurotransmitter, and medication.

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Adrenocortical carcinoma

Adrenocortical carcinoma (ACC, adrenal cortical carcinoma, adrenal cortical cancer, adrenal cortex cancer, etc.) is an aggressive cancer originating in the cortex (steroid hormone-producing tissue) of the adrenal gland.

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Aflatoxin

Aflatoxins are poisonous carcinogens that are produced by certain molds (Aspergillus flavus and Aspergillus parasiticus) which grow in soil, decaying vegetation, hay, and grains.

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Alertness

Alertness is the state of active attention by high sensory awareness such as being watchful and prompt to meet danger or emergency, or being quick to perceive and act.

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Alton Ochsner

Alton Ochsner, Sr. (May 4, 1896 – September 24, 1981), was a surgeon and medical researcher who worked at Tulane University and other New Orleans hospitals before he established The Ochsner Clinic, now known as Ochsner Medical Center.

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Alzheimer's disease

Alzheimer's disease (AD), also referred to simply as Alzheimer's, is a chronic neurodegenerative disease that usually starts slowly and worsens over time.

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American Cancer Society

The American Cancer Society (ACS) is a nationwide voluntary health organization dedicated to eliminating cancer.

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American Lung Association

The American Lung Association is a voluntary health organization whose mission is to save lives by improving lung health and preventing lung disease through education, advocacy and research.

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American Psychologist

American Psychologist is the official peer-reviewed academic journal of the American Psychological Association.

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Amitriptyline

Amitriptyline, sold under the brand name Elavil among others, is a medicine primarily used to treat a number of mental illnesses.

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Angiogenesis

Angiogenesis is the physiological process through which new blood vessels form from pre-existing vessels.

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Animal testing

Animal testing, also known as animal experimentation, animal research and in vivo testing, is the use of non-human animals in experiments that seek to control the variables that affect the behavior or biological system under study.

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Animal testing on rodents

Rodents are commonly used in animal testing, particularly mice and rats, but also guinea pigs, hamsters, gerbils and others.

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Aorta

The aorta is the main artery in the human body, originating from the left ventricle of the heart and extending down to the abdomen, where it splits into two smaller arteries (the common iliac arteries).

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Aortic aneurysm

An aortic aneurysm is an enlargement (dilation) of the aorta to greater than 1.5 times normal size.

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Apoptosis

Apoptosis (from Ancient Greek ἀπόπτωσις "falling off") is a process of programmed cell death that occurs in multicellular organisms.

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Arteriosclerosis

Arteriosclerosis is the thickening, hardening and loss of elasticity of the walls of arteries.

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Associated Press

The Associated Press (AP) is a U.S.-based not-for-profit news agency headquartered in New York City.

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Asthma

Asthma is a common long-term inflammatory disease of the airways of the lungs.

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Atherosclerosis

Atherosclerosis is a disease in which the inside of an artery narrows due to the build up of plaque.

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Austin Bradford Hill

Sir Austin Bradford Hill FRS (8 July 1897 – 18 April 1991), English epidemiologist and statistician, pioneered the randomized clinical trial and, together with Richard Doll, demonstrated the connection between cigarette smoking and lung cancer.

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AZGP1

Zinc-alpha-2-glycoprotein is a protein that in humans is encoded by the AZGP1 gene.

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Bad breath

Bad breath, also known as halitosis, is a symptom in which a noticeably unpleasant odor is present on the breath.

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BBC

The British Broadcasting Corporation (BBC) is a British public service broadcaster.

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Becquerel

The becquerel (symbol: Bq) is the SI derived unit of radioactivity.

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Beedi

A beedi (from बीड़ी; also spelled bidi or biri) is a thin cigarette or mini-cigar filled with tobacco flake and commonly wrapped in a Diospyros melanoxylon or Piliostigma racemosum leaf tied with a string or adhesive at one end.

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Benzopyrene

A benzopyrene is an organic compound with the formula C20H12.

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Bladder cancer

Bladder cancer is any of several types of cancer arising from the tissues of the urinary bladder.

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Blood pressure

Blood pressure (BP) is the pressure of circulating blood on the walls of blood vessels.

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Blood vessel

The blood vessels are the part of the circulatory system, and microcirculation, that transports blood throughout the human body.

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Breast cancer

Breast cancer is cancer that develops from breast tissue.

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British Doctors Study

The British Doctors' Study was a prospective cohort study which ran from 1951 to 2001, and in 1956 provided convincing statistical proof that tobacco smoking increased the risk of lung cancer.

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Bronchus

A bronchus, is a passage of airway in the respiratory system that conducts air into the lungs.

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C. Everett Koop

Charles Everett Koop (October 14, 1916 – February 25, 2013) was an American pediatric surgeon and public health administrator.

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CA (journal)

CA: A Cancer Journal for Clinicians is a bimonthly peer-reviewed medical journal published for the American Cancer Society by Wiley-Blackwell.

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Caffeine

Caffeine is a central nervous system (CNS) stimulant of the methylxanthine class.

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Calmness

Calmness is the mental state of peace of mind being free from agitation, excitement, or disturbance.

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Cancer

Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body.

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Cannabis (drug)

Cannabis, also known as marijuana among other names, is a psychoactive drug from the ''Cannabis'' plant intended for medical or recreational use.

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Carbon monoxide

Carbon monoxide (CO) is a colorless, odorless, and tasteless gas that is slightly less dense than air.

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Carbon monoxide poisoning

Carbon monoxide poisoning typically occurs from breathing in too much carbon monoxide (CO).

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Carcinoembryonic antigen

Carcinoembryonic antigen (CEA) describes a set of highly related glycoproteins involved in cell adhesion.

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Carcinogen

A carcinogen is any substance, radionuclide, or radiation that promotes carcinogenesis, the formation of cancer.

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Cardiovascular disease

Cardiovascular disease (CVD) is a class of diseases that involve the heart or blood vessels.

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Centers for Disease Control and Prevention

The Centers for Disease Control and Prevention (CDC) is the leading national public health institute of the United States.

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Cervical cancer

Cervical cancer is a cancer arising from the cervix.

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Chemical reaction

A chemical reaction is a process that leads to the transformation of one set of chemical substances to another.

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Chewing tobacco

Chewing tobacco is a type of smokeless tobacco product consumed by placing a portion of the tobacco between the cheek and gum or upper lip teeth and chewing.

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Chronic kidney disease

Chronic kidney disease (CKD) is a type of kidney disease in which there is gradual loss of kidney function over a period of months or years.

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Chronic obstructive pulmonary disease

Chronic obstructive pulmonary disease (COPD) is a type of obstructive lung disease characterized by long-term breathing problems and poor airflow.

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Cigar

A cigar is a rolled bundle of dried and fermented tobacco leaves made to be smoked.

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Cigarette

A cigarette is a narrow cylinder containing tobacco that is rolled into thin paper for smoking.

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Cocaine

Cocaine, also known as coke, is a strong stimulant mostly used as a recreational drug.

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Colorectal cancer

Colorectal cancer (CRC), also known as bowel cancer and colon cancer, is the development of cancer from the colon or rectum (parts of the large intestine).

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Concentration

In chemistry, concentration is the abundance of a constituent divided by the total volume of a mixture.

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Confidence interval

In statistics, a confidence interval (CI) is a type of interval estimate, computed from the statistics of the observed data, that might contain the true value of an unknown population parameter.

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Cotinine

Cotinine is an alkaloid found in tobacco and is also the predominant metabolite of nicotine.

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Crohn's disease

Crohn's disease is a type of inflammatory bowel disease (IBD) that may affect any part of the gastrointestinal tract from mouth to anus.

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Crotonaldehyde

Crotonaldehyde is a chemical compound with the formula CH3CH.

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Curie

The curie (symbol Ci) is a non-SI unit of radioactivity originally defined in 1910.

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Cyanide

A cyanide is a chemical compound that contains the group C≡N.

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Cytochrome P450

Cytochromes P450 (CYPs) are proteins of the superfamily containing heme as a cofactor and, therefore, are hemoproteins.

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Developed country

A developed country, industrialized country, more developed country, or "more economically developed country" (MEDC), is a sovereign state that has a highly developed economy and advanced technological infrastructure relative to other less industrialized nations.

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Developing country

A developing country (or a low and middle income country (LMIC), less developed country, less economically developed country (LEDC), underdeveloped country) is a country with a less developed industrial base and a low Human Development Index (HDI) relative to other countries.

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Diabetic nephropathy

Diabetic nephropathy (DN), also known as diabetic kidney disease, is the chronic loss of kidney function occurring in those with diabetes mellitus.

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Dizziness

Dizziness is an impairment in spatial perception and stability.

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DNA

Deoxyribonucleic acid (DNA) is a thread-like chain of nucleotides carrying the genetic instructions used in the growth, development, functioning and reproduction of all known living organisms and many viruses.

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Dopamine

Dopamine (DA, a contraction of 3,4-dihydroxyphenethylamine) is an organic chemical of the catecholamine and phenethylamine families that plays several important roles in the brain and body.

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Dopaminergic

Dopaminergic means "related to dopamine" (literally, "working on dopamine"), dopamine being a common neurotransmitter.

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Dresden

Dresden (Upper and Lower Sorbian: Drježdźany, Drážďany, Drezno) is the capital city and, after Leipzig, the second-largest city of the Free State of Saxony in Germany.

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Drug tolerance

Drug tolerance is a pharmacological concept describing subjects' reduced reaction to a drug following its repeated use.

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E. Cuyler Hammond

E.

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Edward Martell

Edward A. Martell (1920? – July 12, 1995) was an American radiochemist for the US National Center for Atmospheric Research (NCAR) in Boulder, Colorado.

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Electrophile

In organic chemistry, an electrophile is a reagent attracted to electrons.

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Endometriosis

Endometriosis is a condition in which the endometrium, the layer of tissue that normally covers the inside of the uterus, grows outside of it.

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Endometrium

The endometrium is the inner epithelial layer, along with its mucous membrane, of the mammalian uterus.

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Endothelium

Endothelium refers to cells that line the interior surface of blood vessels and lymphatic vessels, forming an interface between circulating blood or lymph in the lumen and the rest of the vessel wall.

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Epidemiology

Epidemiology is the study and analysis of the distribution (who, when, and where) and determinants of health and disease conditions in defined populations.

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Epithelium

Epithelium is one of the four basic types of animal tissue, along with connective tissue, muscle tissue and nervous tissue.

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Epoxide

An epoxide is a cyclic ether with a three-atom ring.

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Erectile dysfunction

Erectile dysfunction (ED), also known as impotence, is a type of sexual dysfunction characterized by the inability to develop or maintain an erection of the penis during sexual activity.

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Esophageal cancer

Esophageal cancer is cancer arising from the esophagus—the food pipe that runs between the throat and the stomach.

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Estrogen

Estrogen, or oestrogen, is the primary female sex hormone.

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Ethanol

Ethanol, also called alcohol, ethyl alcohol, grain alcohol, and drinking alcohol, is a chemical compound, a simple alcohol with the chemical formula.

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Expert Review of Cardiovascular Therapy

Expert Review of Cardiovascular Therapy is a monthly peer-reviewed medical journal covering all aspects of cardiology.

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Fatty acid

In chemistry, particularly in biochemistry, a fatty acid is a carboxylic acid with a long aliphatic chain, which is either saturated or unsaturated.

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Female infertility

Female infertility refers to infertility in female humans.

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Fetus

A fetus is a stage in the prenatal development of viviparous organisms.

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Fibrinogen

Fibrinogen (factor I) is a glycoprotein that in vertebrates circulates in the blood.

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Folliculogenesis

In biology, folliculogenesis is the maturation of the ovarian follicle, a densely packed shell of somatic cells that contains an immature oocyte.

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Fritz Lickint

Fritz Balduin Lickint (1 October 1898 – 7 July 1960) was a German internist and social democrat, who investigated scientifically health problems and social problems related to alcohol and tobacco, described in the 1920s cancer of the lung from smoking and, the cancer pathway alongside the respiratory and upper digestive tract.

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Gallbladder cancer

Gallbladder cancer is a relatively uncommon cancer.

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Germany

Germany (Deutschland), officially the Federal Republic of Germany (Bundesrepublik Deutschland), is a sovereign state in central-western Europe.

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Gideon Lincecum

Gideon Lincecum (22 April 1793 – 28 November 1874) was an American pioneer, historian, physician, philosopher, and naturalist.

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Gingival recession

Gingival recession, also known as receding gums, is the exposure in the roots of the teeth caused by a loss of gum tissue and/or retraction of the gingival margin from the crown of the teeth.

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Guanine

Guanine (or G, Gua) is one of the four main nucleobases found in the nucleic acids DNA and RNA, the others being adenine, cytosine, and thymine (uracil in RNA).

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Harmane

Harmane (harman) is a heterocyclic amine found in a variety of foods including coffee, sauces, and cooked meat.

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Head and neck cancer

Head and neck cancer is a group of cancers that starts in the mouth, nose, throat, larynx, sinuses, or salivary glands.

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Hemiaminal

A hemiaminal (also carbinolamine) is a functional group or type of chemical compound that has a hydroxyl group and an amine attached to the same carbon atom: -C(OH)(NR2)-.

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Heroin

Heroin, also known as diamorphine among other names, is an opioid most commonly used as a recreational drug for its euphoric effects.

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High-density lipoprotein

High-density lipoproteins (HDL) are one of the five major groups of lipoproteins.

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HIV

The human immunodeficiency virus (HIV) is a lentivirus (a subgroup of retrovirus) that causes HIV infection and over time acquired immunodeficiency syndrome (AIDS).

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Hookah

A hookah (from Hindustani: हुक़्क़ा (Devanagari), (Nastaleeq), IPA:; also see other names), also known as the ḡalyān (Persian: قلیان), is a single- or multi-stemmed instrument for vaporizing and smoking flavored tobacco (often Mu‘assel), or sometimes cannabis or opium, whose vapor or smoke is passed through a water basin—often glass-based—before inhalation.

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Hormone

A hormone (from the Greek participle “ὁρμῶ”, "to set in motion, urge on") is any member of a class of signaling molecules produced by glands in multicellular organisms that are transported by the circulatory system to target distant organs to regulate physiology and behaviour.

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Human musculoskeletal system

The human musculoskeletal system (also known as the locomotor system, and previously the activity system) is an organ system that gives humans the ability to move using their muscular and skeletal systems.

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Hydrophobe

In chemistry, hydrophobicity is the physical property of a molecule (known as a hydrophobe) that is seemingly repelled from a mass of water.

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Hypercholesterolemia

Hypercholesterolemia, also called high cholesterol, is the presence of high levels of cholesterol in the blood.

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Hypertension

Hypertension (HTN or HT), also known as high blood pressure (HBP), is a long-term medical condition in which the blood pressure in the arteries is persistently elevated.

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In vitro fertilisation

In vitro fertilisation (IVF) is a process of fertilisation where an egg is combined with sperm outside the body, in vitro ("in glass").

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International Agency for Research on Cancer

The International Agency for Research on Cancer (IARC; Centre International de Recherche sur le Cancer, CIRC) is an intergovernmental agency forming part of the World Health Organization of the United Nations.

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IRIN

IRIN (formerly Integrated Regional Information Networks) is a news agency focusing on humanitarian stories in regions that are often forgotten, under-reported, misunderstood or ignored.

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Irving Fisher

Irving Fisher (February 27, 1867 – April 29, 1947) was an American economist, statistician, inventor, and Progressive social campaigner.

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Isotopes of lead

Lead (82Pb) has four stable isotopes: 204Pb, 206Pb, 207Pb, 208Pb.

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Isotopes of polonium

Polonium (84Po) has 33 isotopes, all of which are radioactive, with between 186 and 227 nucleons.

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James A. Schoenberger

James A. Schoenberger, MD (1919–2011) was a Chicago cardiologist and medical research scientist who participated in early epidemiological studies and clinical trials that provided evidence linking smoking and other risk factors to cardiovascular diseases.

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Johns Hopkins University

Johns Hopkins University is an American private research university in Baltimore, Maryland.

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Journal of Periodontology

The Journal of Periodontology is the learned journal of the American Academy of Periodontology (AAP).

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Journal of the National Cancer Institute

The Journal of the National Cancer Institute (JNCI) is a peer-reviewed medical journal covering research in oncology that was established in August 1940.

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Judgement

Judgement (or judgment) is the evaluation of evidence to make a decision.

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Kaposi's sarcoma

Kaposi's sarcoma (KS) is a type of cancer that can form masses in the skin, lymph nodes, or other organs.

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Kidney

The kidneys are two bean-shaped organs present in left and right sides of the body in vertebrates.

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Kidney cancer

Kidney cancer, also known as renal cancer, is a type of cancer that starts in the cells in the kidney.

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Language

Language is a system that consists of the development, acquisition, maintenance and use of complex systems of communication, particularly the human ability to do so; and a language is any specific example of such a system.

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Laryngeal cancer

Laryngeal cancer, also known as cancer of the larynx or laryngeal carcinoma, are mostly squamous cell carcinomas, reflecting their origin from the skin of the larynx.

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Larynx

The larynx, commonly called the voice box, is an organ in the top of the neck of tetrapods involved in breathing, producing sound, and protecting the trachea against food aspiration.

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Lesion

A lesion is any abnormal damage or change in the tissue of an organism, usually caused by disease or trauma.

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Leukoplakia

Leukoplakia generally refers to a firmly attached white patch on a mucous membrane which is associated with an increased risk of cancer.

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Lipolysis

Lipolysis is the breakdown of lipids and involves hydrolysis of triglycerides into glycerol and free fatty acids.

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List of cigarette smoke carcinogens

Commercial tobacco smoke is a mixture of more than 5000 chemicals.

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Liver cancer

Liver cancer, also known as hepatic cancer and primary hepatic cancer, is cancer that starts in the liver.

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Logarithm

In mathematics, the logarithm is the inverse function to exponentiation.

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Longitudinal study

A longitudinal study (or longitudinal survey, or panel study) is a research design that involves repeated observations of the same variables (e.g., people) over short or long periods of time (i.e., uses longitudinal data).

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Low birth weight

Low birth weight (LBW) is defined by the World Health Organization as a birth weight of a infant of 2,499 g or less, regardless of gestational age.

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Low-density lipoprotein

Low-density lipoprotein (LDL) is one of the five major groups of lipoprotein which transport all fat molecules around the body in the extracellular water.

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Lung cancer

Lung cancer, also known as lung carcinoma, is a malignant lung tumor characterized by uncontrolled cell growth in tissues of the lung.

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Major depressive disorder

Major depressive disorder (MDD), also known simply as depression, is a mental disorder characterized by at least two weeks of low mood that is present across most situations.

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Mayo Clinic

The Mayo Clinic is a nonprofit academic medical center based in Rochester, Minnesota focused on integrated clinical practice, education, and research.

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McGill University

McGill University is a public research university in Montreal, Quebec, Canada.

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Memorial Sloan Kettering Cancer Center

Memorial Sloan Kettering Cancer Center (MSK or MSKCC) is a cancer treatment and research institution in New York City, founded in 1884 as the New York Cancer Hospital.

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Merchants of Doubt

Merchants of Doubt: How a Handful of Scientists Obscured the Truth on Issues from Tobacco Smoke to Global Warming is a 2010 non-fiction book by American historians of science Naomi Oreskes and Erik M. Conway.

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Michael reaction

The Michael reaction or Michael addition is the nucleophilic addition of a carbanion or another nucleophile to an α,β-unsaturated carbonyl compound.

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Miscarriage

Miscarriage, also known as spontaneous abortion and pregnancy loss, is the natural death of an embryo or fetus before it is able to survive independently.

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Monoamine oxidase B

Monoamine oxidase B, also known as MAOB, is an enzyme that in humans is encoded by the MAOB gene.

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Monoamine oxidase inhibitor

Monoamine oxidase inhibitors (MAOIs) are a class of drugs that inhibit the activity of one or both monoamine oxidase enzymes: monoamine oxidase A (MAO-A) and monoamine oxidase B (MAO-B).

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Motor skill

A motor skill is a learned ability to cause a predetermined movement outcome with maximum certainty.

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Mouth

In animal anatomy, the mouth, also known as the oral cavity, buccal cavity, or in Latin cavum oris, is the opening through which many animals take in food and issue vocal sounds.

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Mutagen

In genetics, a mutagen is a physical or chemical agent that changes the genetic material, usually DNA, of an organism and thus increases the frequency of mutations above the natural background level.

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Mutation

In biology, a mutation is the permanent alteration of the nucleotide sequence of the genome of an organism, virus, or extrachromosomal DNA or other genetic elements.

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Myeloid leukemia

Myeloid leukemia is a type of leukemia affecting myeloid tissue.

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Myocardial infarction

Myocardial infarction (MI), commonly known as a heart attack, occurs when blood flow decreases or stops to a part of the heart, causing damage to the heart muscle.

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Myometrium

The myometrium is the middle layer of the uterine wall, consisting mainly of uterine smooth muscle cells (also called uterine myocytes), but also of supporting stromal and vascular tissue.

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National Cancer Institute

The National Cancer Institute (NCI) is part of the National Institutes of Health (NIH), which is one of eleven agencies that are part of the U.S. Department of Health and Human Services.

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National Center for Atmospheric Research

The US National Center for Atmospheric Research (NCAR) is a US federally funded research and development center (FFRDC) managed by the nonprofit University Corporation for Atmospheric Research (UCAR) and funded by the National Science Foundation (NSF).

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National Institutes of Health

The National Institutes of Health (NIH) is the primary agency of the United States government responsible for biomedical and public health research, founded in the late 1870s.

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Nausea

Nausea or queasiness is an unpleasant sense of unease, discomfort, and revulsion towards food.

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Neural tube defect

Neural tube defects (NTDs) are a group of birth defects in which an opening in the spinal cord or brain remains from early in human development.

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New York City

The City of New York, often called New York City (NYC) or simply New York, is the most populous city in the United States.

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Nicotine

Nicotine is a potent parasympathomimetic stimulant and an alkaloid found in the nightshade family of plants.

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Nicotine gum

Nicotine gum is a type of chewing gum that delivers nicotine to the body.

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Nicotine patch

A nicotine patch is a transdermal patch that releases nicotine into the body through the skin.

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Nicotine withdrawal

Nicotine withdrawal is a group of symptoms that occur in the first few weeks upon the abrupt discontinuation or decrease in intake of nicotine.

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Nitrosamine

Nitrosamines are chemical compounds of the chemical structure R1N(–R2)–N.

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NNK

Nicotine-derived nitrosamine ketone (NNK), also known as 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, is one of the key tobacco-specific nitrosamines which play an important role in carcinogenesis.

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Nucleophilic conjugate addition

Nucleophilic conjugate addition is a type of organic reaction.

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Oncogene

An oncogene is a gene that has the potential to cause cancer.

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Oral cancer

Oral cancer, also known as mouth cancer, is a type of head and neck cancer and is any cancerous tissue growth located in the oral cavity.

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Ovary

The ovary is an organ found in the female reproductive system that produces an ovum.

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Ovulation

Ovulation is the release of eggs from the ovaries.

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Oxygen

Oxygen is a chemical element with symbol O and atomic number 8.

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Pakistan

Pakistan (پاکِستان), officially the Islamic Republic of Pakistan (اِسلامی جمہوریہ پاکِستان), is a country in South Asia.

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Pancreatic cancer

Pancreatic cancer arises when cells in the pancreas, a glandular organ behind the stomach, begin to multiply out of control and form a mass.

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Parkinson's disease

Parkinson's disease (PD) is a long-term degenerative disorder of the central nervous system that mainly affects the motor system.

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Passive smoking

Passive smoking is the inhalation of smoke, called second-hand smoke (SHS), or environmental tobacco smoke (ETS), by persons other than the intended "active" smoker.

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Pediatrics (journal)

Pediatrics is a peer-reviewed medical journal published by the American Academy of Pediatrics.

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Periodontal disease

Periodontal disease, also known as gum disease, is a set of inflammatory conditions affecting the tissues surrounding the teeth.

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Periodontology

Periodontology or periodontics (from Greek περί peri "around"; and ὀδούς odous "tooth", genitive ὀδόντος odontos) is the specialty of dentistry that studies supporting structures of teeth, as well as diseases and conditions that affect them.

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Peripheral artery disease

Peripheral artery disease (PAD) is a narrowing of the arteries other than those that supply the heart or the brain.

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Peter Jennings

Peter Charles Archibald Ewart Jennings (July 29, 1938August 7, 2005) was a Canadian-American journalist who served as the sole anchor of ABC World News Tonight for 22 years from 1983 until his death from lung cancer in 2005.

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Philip Morris International

Philip Morris International Inc. (PMI) is an American multinational cigarette and tobacco manufacturing company, with products sold in over 180 countries outside the United States.

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Platelet

Platelets, also called thrombocytes (from Greek θρόμβος, "clot" and κύτος, "cell"), are a component of blood whose function (along with the coagulation factors) is to react to bleeding from blood vessel injury by clumping, thereby initiating a blood clot.

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Pneumonia

Pneumonia is an inflammatory condition of the lung affecting primarily the small air sacs known as alveoli.

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Polycyclic aromatic hydrocarbon

Polycyclic aromatic hydrocarbons (PAHs, also polyaromatic hydrocarbons or polynuclear aromatic hydrocarbons) are hydrocarbons—organic compounds containing only carbon and hydrogen—that are composed of multiple aromatic rings (organic rings in which the electrons are delocalized).

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Pregnancy

Pregnancy, also known as gestation, is the time during which one or more offspring develops inside a woman.

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Preterm birth

Preterm birth, also known as premature birth, is the birth of a baby at fewer than 37 weeks gestational age.

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Preventable causes of death

The World Health Organization has traditionally classified death according to the primary type of disease or injury.

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Programmed cell death

Programmed cell death (or PCD) is the death of a cell in any form, mediated by an intracellular program.

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Psychoactive drug

A psychoactive drug, psychopharmaceutical, or psychotropic is a chemical substance that changes brain function and results in alterations in perception, mood, consciousness, cognition, or behavior.

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Psychology

Psychology is the science of behavior and mind, including conscious and unconscious phenomena, as well as feeling and thought.

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Pulmonary alveolus

A pulmonary alveolus (plural: alveoli, from Latin alveolus, "little cavity") is a hollow cavity found in the lung parenchyma, and is the basic unit of ventilation.

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Pyrolysis

Pyrolysis is the thermal decomposition of materials at elevated temperatures in an inert atmosphere.

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Radioactive decay

Radioactive decay (also known as nuclear decay or radioactivity) is the process by which an unstable atomic nucleus loses energy (in terms of mass in its rest frame) by emitting radiation, such as an alpha particle, beta particle with neutrino or only a neutrino in the case of electron capture, gamma ray, or electron in the case of internal conversion.

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Radiochemistry

Radiochemistry is the chemistry of radioactive materials, where radioactive isotopes of elements are used to study the properties and chemical reactions of non-radioactive isotopes (often within radiochemistry the absence of radioactivity leads to a substance being described as being inactive as the isotopes are stable).

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Raven's Progressive Matrices

Raven's Progressive Matrices (often referred to simply as Raven's Matrices) or RPM is a nonverbal group test typically used in educational settings.

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Reader's Digest

Reader's Digest is an American general-interest family magazine, published ten times a year.

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Recreational drug use

Recreational drug use is the use of a psychoactive drug to induce an altered state of consciousness for pleasure, by modifying the perceptions, feelings, and emotions of the user.

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Relaxation (psychology)

Relaxation in psychology, is the emotional state of a living being, of low tension, in which there is an absence of arousal that could come from sources such as anger, anxiety, or fear.

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Respiratory system

The respiratory system (also respiratory apparatus, ventilatory system) is a biological system consisting of specific organs and structures used for gas exchange in animals and plants.

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Respiratory tract infection

Respiratory tract infection (RTI) refers to any of a number of infectious diseases involving the respiratory tract.

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Reuters

Reuters is an international news agency headquartered in London, United Kingdom.

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Richard Doll

Sir William Richard Shaboe Doll (28 October 1912 – 24 July 2005) was a British physiologist who became an epidemiologist in the 20th century, turning the subject into a rigorous science.

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Richard Peto

Sir Richard Peto (born 14 May 1943) is Professor of Medical Statistics and Epidemiology at the University of Oxford, England.

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Risk

Risk is the potential of gaining or losing something of value.

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Risk factor

In epidemiology, a risk factor is a variable associated with an increased risk of disease or infection.

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Schizophrenia

Schizophrenia is a mental disorder characterized by abnormal social behavior and failure to understand reality.

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Schizophrenia and smoking

Studies across 20 countries show a strong association between schizophrenia and smoking, whereby people with schizophrenia are much more likely to smoke than those without the disease.

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Sensitization

Sensitization is a non-associative learning process in which repeated administration of a stimulus results in the progressive amplification of a response.

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Sievert

The sievert (symbol: SvNot be confused with the sverdrup or the svedberg, two non-SI units that sometimes use the same symbol.) is a derived unit of ionizing radiation dose in the International System of Units (SI) and is a measure of the health effect of low levels of ionizing radiation on the human body.

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Small intestine cancer

In oncology, small intestine cancer, also small bowel cancer and cancer of the small bowel, is a cancer of the small intestine.

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Small-cell carcinoma

Small-cell carcinoma (also known as "small-cell lung cancer", or "oat-cell carcinoma") is a type of highly malignant cancer that most commonly arises within the lung, although it can occasionally arise in other body sites, such as the cervix, prostate, and gastrointestinal tract.

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Smoking and Health: Report of the Advisory Committee to the Surgeon General of the United States

Smoking and Health: Report of the Advisory Committee to the Surgeon General of the United States was a landmark report published on January 11, 1964 by the Surgeon General's Advisory Committee on Smoking and Health, chaired by then-Surgeon General of the United States Luther Terry regarding the negative health effects of tobacco smoking.

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Smoking and pregnancy

Tobacco smoking and pregnancy is related to many effects on health and reproduction, in addition to the general health effects of tobacco.

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Smoking ban

Smoking bans (or smoke-free laws) are public policies, including criminal laws and occupational safety and health regulations, that prohibit tobacco smoking in workplaces and other public spaces.

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Smoking cessation

Smoking cessation (also known as quitting smoking or simply quitting) is the process of discontinuing tobacco smoking.

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Snuff (tobacco)

Snuff is a smokeless tobacco made from ground or pulverised tobacco leaves.

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Sputum

Sputum is mucus and is the name used for the coughed-up material (phlegm) from the lower airways (trachea and bronchi).

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Squamous cell carcinoma

Squamous cell carcinomas, also known as epidermoid carcinoma are a number of different types of cancer that result from squamous cells.

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Stimulant

Stimulants (also often referred to as psychostimulants or colloquially as uppers) is an overarching term that covers many drugs including those that increase activity of the central nervous system and the body, drugs that are pleasurable and invigorating, or drugs that have sympathomimetic effects.

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Stochastic

The word stochastic is an adjective in English that describes something that was randomly determined.

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Stomach cancer

Stomach cancer, also known as gastric cancer, is cancer developing from the lining of the stomach.

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Streptococcus pneumoniae

Streptococcus pneumoniae, or pneumococcus, is a Gram-positive, alpha-hemolytic (under aerobic conditions) or beta-hemolytic (under anaerobic conditions), facultative anaerobic member of the genus Streptococcus.

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Stroke

A stroke is a medical condition in which poor blood flow to the brain results in cell death.

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Sudden infant death syndrome

Sudden infant death syndrome (SIDS), also known as cot death or crib death, is the sudden unexplained death of a child less than one year of age.

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Sulfur mustard

Sulfur mustard, commonly known as mustard gas, is the prototypical substance of the sulfur-based family of cytotoxic and vesicant chemical warfare agents known as the sulfur mustards which have the ability to form large blisters on exposed skin and in the lungs.

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Surgeon General of the United States

The Surgeon General of the United States is the operational head of the U.S. Public Health Service Commissioned Corps (PHSCC) and thus the leading spokesperson on matters of public health in the federal government of the United States.

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Tachycardia

Tachycardia, also called tachyarrhythmia, is a heart rate that exceeds the normal resting rate.

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Tar (tobacco residue)

Tar is the common name for the resinous, partially combusted particulate matter produced by the burning of tobacco and other plant material in the act of smoking.

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The Australian

The Australian is a broadsheet newspaper published in Australia from Monday to Saturday each week since 14 July 1964.

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The BMJ

The BMJ is a weekly peer-reviewed medical journal.

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The Independent Florida Alligator

The Independent Florida Alligator is the daily student newspaper of the University of Florida.

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Third-hand smoke

Third-hand smoke is contamination by tobacco smoke that lingers following the extinguishing of a cigarette, cigar, or other combustible tobacco product.

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Throat

In vertebrate anatomy, the throat is the front part of the neck, positioned in front of the vertebra.

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Thromboangiitis obliterans

Thromboangiitis obliterans, also known as Buerger disease (English, German), is a recurring progressive inflammation and thrombosis (clotting) of small and medium arteries and veins of the hands and feet.

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Titration

Titration, also known as titrimetry, is a common laboratory method of quantitative chemical analysis that is used to determine the concentration of an identified analyte.

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Tobacco

Tobacco is a product prepared from the leaves of the tobacco plant by curing them.

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Tobacco control

Tobacco control is a field of international public health science, policy and practice dedicated to addressing tobacco use and thereby reducing the morbidity and mortality it causes.

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Tobacco packaging warning messages

Tobacco package warning messages are warning messages that appear on the packaging of cigarettes and other tobacco products concerning their health effects.

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Tobacco pipe

A tobacco pipe, often called simply a pipe, is a device specifically made to smoke tobacco.

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Tobacco smoking

Tobacco smoking is the practice of smoking tobacco and inhaling tobacco smoke (consisting of particle and gaseous phases).

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Toxication

Toxication or toxification is the conversion of a chemical compound into a more toxic form in living organisms or in substrates such as soil or water.

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Tumor suppressor

A tumor suppressor gene, or antioncogene, is a gene that protects a cell from one step on the path to cancer.

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United States Army

The United States Army (USA) is the land warfare service branch of the United States Armed Forces.

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USA Today

USA Today is an internationally distributed American daily, middle-market newspaper that serves as the flagship publication of its owner, the Gannett Company.

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Uterine fibroid

Uterine fibroids, also known as uterine leiomyomas or fibroids, are benign smooth muscle tumors of the uterus.

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Uterus

The uterus (from Latin "uterus", plural uteri) or womb is a major female hormone-responsive secondary sex organ of the reproductive system in humans and most other mammals.

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Valproate

Valproate (VPA), and its valproic acid, sodium valproate, and valproate semisodium forms, are medications primarily used to treat epilepsy and bipolar disorder and to prevent migraine headaches.

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Vaporizer (inhalation device)

A vaporizer or vaporiser (a ‘vape’) is a device used to vaporize substances for inhalation.

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Vitamin C

Vitamin C, also known as ascorbic acid and L-ascorbic acid, is a vitamin found in food and used as a dietary supplement.

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Wide-body aircraft

A wide-body aircraft is a jet airliner with a fuselage wide enough to accommodate two passenger aisles, also known as twin-aisle aircraft, with seven or more seats abreast.

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World Health Organization

The World Health Organization (WHO; French: Organisation mondiale de la santé) is a specialized agency of the United Nations that is concerned with international public health.

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World War I

World War I (often abbreviated as WWI or WW1), also known as the First World War, the Great War, or the War to End All Wars, was a global war originating in Europe that lasted from 28 July 1914 to 11 November 1918.

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Xerostomia

Xerostomia, also known as dry mouth and dry mouth syndrome, is dryness in the mouth, which may be associated with a change in the composition of saliva, or reduced salivary flow, or have no identifiable cause.

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1950 Wynder and Graham Study

The 1950 Wynder and Graham Study was conducted by Ernest Wynder and Evarts Graham and was entitled "Tobacco Smoking as a Possible Etiologic Factor in Bronchiogenic Carcinoma: A Study of Six Hundred and Eighty-Four Proved Cases".

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References

[1] https://en.wikipedia.org/wiki/Health_effects_of_tobacco

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