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Insulin regulatory sequence

Index Insulin regulatory sequence

Transcription of insulin is regulated by the binding of various transcription factors to the ~400 base pairs before the insulin transcription start site, called the "insulin regulatory sequence". [1]

Table of Contents

  1. 26 relations: Adenosine, Base pair, Basic helix–loop–helix, CAMP responsive element modulator, CREB, DBP (gene), Glucocorticoid receptor, Homeobox, Homeobox protein CDX-2, Insulin, Insulin regulatory sequence, ISL1, MAF (gene), NEUROD1, PAX4, PAX6, PDX1, POU2F1, Regulatory sequence, TCF12, TCF3, Thymidine, Transcription (biology), Transcription factor, USF1, USF2.

  2. Insulin
  3. Regulatory sequences

Adenosine

Adenosine (symbol A) is an organic compound that occurs widely in nature in the form of diverse derivatives.

See Insulin regulatory sequence and Adenosine

Base pair

A base pair (bp) is a fundamental unit of double-stranded nucleic acids consisting of two nucleobases bound to each other by hydrogen bonds.

See Insulin regulatory sequence and Base pair

Basic helix–loop–helix

A basic helix–loop–helix (bHLH) is a protein structural motif that characterizes one of the largest families of dimerizing transcription factors.

See Insulin regulatory sequence and Basic helix–loop–helix

CAMP responsive element modulator

cAMP responsive element modulator is a protein that in humans is encoded by the CREM gene, and it belongs to the cAMP-responsive element binding protein family.

See Insulin regulatory sequence and CAMP responsive element modulator

CREB

CREB-TF (CREB, cAMP response element-binding protein) is a cellular transcription factor.

See Insulin regulatory sequence and CREB

DBP (gene)

D site of albumin promoter (albumin D-box) binding protein, also known as DBP, is a protein which in humans is encoded by the DBP gene.

See Insulin regulatory sequence and DBP (gene)

Glucocorticoid receptor

The glucocorticoid receptor (GR or GCR) also known as NR3C1 (nuclear receptor subfamily 3, group C, member 1) is the receptor to which cortisol and other glucocorticoids bind.

See Insulin regulatory sequence and Glucocorticoid receptor

Homeobox

A homeobox is a DNA sequence, around 180 base pairs long, that regulates large-scale anatomical features in the early stages of embryonic development.

See Insulin regulatory sequence and Homeobox

Homeobox protein CDX-2

Homeobox protein CDX-2 is a protein that in humans is encoded by the CDX2 gene.

See Insulin regulatory sequence and Homeobox protein CDX-2

Insulin

Insulin (from Latin insula, 'island') is a peptide hormone produced by beta cells of the pancreatic islets encoded in humans by the insulin (INS) gene.

See Insulin regulatory sequence and Insulin

Insulin regulatory sequence

Transcription of insulin is regulated by the binding of various transcription factors to the ~400 base pairs before the insulin transcription start site, called the "insulin regulatory sequence". Insulin regulatory sequence and insulin regulatory sequence are insulin and regulatory sequences.

See Insulin regulatory sequence and Insulin regulatory sequence

ISL1

Insulin gene enhancer protein ISL-1 is a protein that in humans is encoded by the ISL1 gene.

See Insulin regulatory sequence and ISL1

MAF (gene)

Transcription factor Maf also known as proto-oncogene c-Maf or V-maf musculoaponeurotic fibrosarcoma oncogene homolog is a transcription factor that in humans is encoded by the MAF gene.

See Insulin regulatory sequence and MAF (gene)

NEUROD1

Neurogenic differentiation 1 (Neurod1), also called β2, is a transcription factor of the NeuroD-type.

See Insulin regulatory sequence and NEUROD1

PAX4

Paired box gene 4, also known as PAX4, is a protein which in humans is encoded by the PAX4 gene.

See Insulin regulatory sequence and PAX4

PAX6

Paired box protein Pax-6, also known as aniridia type II protein (AN2) or oculorhombin, is a protein that in humans is encoded by the PAX6 gene.

See Insulin regulatory sequence and PAX6

PDX1

PDX1 (pancreatic and duodenal homeobox 1), also known as insulin promoter factor 1, is a transcription factor in the ParaHox gene cluster.

See Insulin regulatory sequence and PDX1

POU2F1

POU domain, class 2, transcription factor 1 is a protein that in humans is encoded by the POU2F1 gene.

See Insulin regulatory sequence and POU2F1

Regulatory sequence

A regulatory sequence is a segment of a nucleic acid molecule which is capable of increasing or decreasing the expression of specific genes within an organism. Insulin regulatory sequence and regulatory sequence are regulatory sequences.

See Insulin regulatory sequence and Regulatory sequence

TCF12

Transcription factor 12 is a protein that in humans is encoded by the TCF12 gene.

See Insulin regulatory sequence and TCF12

TCF3

Transcription factor 3 (E2A immunoglobulin enhancer-binding factors E12/E47), also known as TCF3, is a protein that in humans is encoded by the TCF3 gene.

See Insulin regulatory sequence and TCF3

Thymidine

Thymidine (symbol dT or dThd), also known as deoxythymidine, deoxyribosylthymine, or thymine deoxyriboside, is a pyrimidine deoxynucleoside.

See Insulin regulatory sequence and Thymidine

Transcription (biology)

Transcription is the process of copying a segment of DNA into RNA.

See Insulin regulatory sequence and Transcription (biology)

Transcription factor

In molecular biology, a transcription factor (TF) (or sequence-specific DNA-binding factor) is a protein that controls the rate of transcription of genetic information from DNA to messenger RNA, by binding to a specific DNA sequence.

See Insulin regulatory sequence and Transcription factor

USF1

Upstream stimulatory factor 1 is a protein that in humans is encoded by the USF1 gene.

See Insulin regulatory sequence and USF1

USF2

Upstream stimulatory factor 2 is a protein that in humans is encoded by the USF2 gene.

See Insulin regulatory sequence and USF2

See also

Insulin

Regulatory sequences

References

[1] https://en.wikipedia.org/wiki/Insulin_regulatory_sequence

Also known as A-box 1 of insulin gene, A-box 2 of insulin gene, A-box 3 of insulin gene, A-box 5 of insulin gene, A2 regulatory sequence, A3 regulatory sequence, A5 regulatory sequence, C-box 1 of insulin gene, C-box 2 of insulin gene, C1 regulatory sequence, C2 regulatory sequence, CAAT enhancer binding, E-box 1 of insulin gene, E-box 2 of insulin gene, E1 regulatory sequence, E2 regulatory sequence, G-box 1 of insulin gene, G1 regulatory sequence, ILPR, Insulin-linked polymorphic region, Z regulatory sequence, Z-box of insulin gene.