Table of Contents
65 relations: Addiction, Alzheimer's disease, Aplysia, ATF1, ATF4, Brain-derived neurotrophic factor, Brown rat, BZIP domain, Calcium, CAMK, CAMP responsive element modulator, Casein kinase 2, Cell nucleus, Circadian clock, Corticotropin-releasing hormone, CREB in cognition, CREB-binding protein, CREB1, CREB3, CREB3L1, CREB5, Cyclic adenosine monophosphate, Dentate gyrus, DNA, DNA methylation, Drosophila melanogaster, Enhancer (genetics), Enkephalin, Entrainment (chronobiology), G protein-coupled receptor, Gene, Huntington's disease, Intrinsically photosensitive retinal ganglion cell, Leucine zipper, Long-term memory, Long-term potentiation, Major depressive disorder, Melanopsin, Michael E. Greenberg, Neuron, Neuropeptide, Neuroplasticity, NMDA receptor, Norepinephrine, PER2, Period (gene), Period circadian protein homolog 1, Promoter (genetics), Protein c-Fos, Protein kinase, ... Expand index (15 more) »
Addiction
Addiction is a neuropsychological disorder characterized by a persistent and intense urge to use a drug or engage in a behavior that produces natural reward, despite substantial harm and other negative consequences.
Alzheimer's disease
Alzheimer's disease (AD) is a neurodegenerative disease that usually starts slowly and progressively worsens, and is the cause of 60–70% of cases of dementia.
See CREB and Alzheimer's disease
Aplysia
Aplysia is a genus of medium-sized to extremely large sea slugs, specifically sea hares, which are a kind of marine gastropod mollusk.
See CREB and Aplysia
ATF1
Cyclic AMP-dependent transcription factor ATF-1 is a protein that in humans is encoded by the ATF1 gene. CREB and ATF1 are transcription factors.
See CREB and ATF1
ATF4
Activating transcription factor 4 (tax-responsive enhancer element B67), also known as ATF4, is a protein that in humans is encoded by the ATF4 gene. CREB and ATF4 are transcription factors.
See CREB and ATF4
Brain-derived neurotrophic factor
Brain-derived neurotrophic factor (BDNF), or abrineurin, is a protein found in the and the periphery.
See CREB and Brain-derived neurotrophic factor
Brown rat
The brown rat (Rattus norvegicus), also known as the common rat, street rat, sewer rat, wharf rat, Hanover rat, Norway rat and Norwegian rat, is a widespread species of common rat.
BZIP domain
The Basic Leucine Zipper Domain (bZIP domain) is found in many DNA binding eukaryotic proteins.
Calcium
Calcium is a chemical element; it has symbol Ca and atomic number 20.
See CREB and Calcium
CAMK
CAMK, also written as CaMK or CCaMK, is an abbreviation for the Ca2+/calmodulin-dependent protein kinase class of enzymes.
See CREB and CAMK
CAMP responsive element modulator
cAMP responsive element modulator is a protein that in humans is encoded by the CREM gene, and it belongs to the cAMP-responsive element binding protein family. CREB and cAMP responsive element modulator are transcription factors.
See CREB and CAMP responsive element modulator
Casein kinase 2
Casein kinase 2(CK2/CSNK2) is a serine/threonine-selective protein kinase that has been implicated in cell cycle control, DNA repair, regulation of the circadian rhythm, and other cellular processes.
Cell nucleus
The cell nucleus (nuclei) is a membrane-bound organelle found in eukaryotic cells.
Circadian clock
A circadian clock, or circadian oscillator, also known as one’s internal alarm clock is a biochemical oscillator that cycles with a stable phase and is synchronized with solar time.
Corticotropin-releasing hormone
Corticotropin-releasing hormone (CRH) (also known as corticotropin-releasing factor (CRF) or corticoliberin; corticotropin may also be spelled corticotrophin) is a peptide hormone involved in stress responses.
See CREB and Corticotropin-releasing hormone
CREB in cognition
The cellular transcription factor CREB (cAMP response element-binding protein) helps learning and the stabilization and retrieval of fear-based, long-term memories.
See CREB and CREB in cognition
CREB-binding protein
CREB-binding protein, also known as CREBBP or CBP or KAT3A, (where CREB is cAMP response element-binding protein) is a coactivator encoded by the CREBBP gene in humans, located on chromosome 16p13.3.
See CREB and CREB-binding protein
CREB1
CAMP responsive element binding protein 1, also known as CREB-1, is a protein that in humans is encoded by the CREB1 gene. CREB and CREB1 are transcription factors.
See CREB and CREB1
CREB3
Cyclic AMP-responsive element-binding protein 3 is a protein that in humans is encoded by the CREB3 gene. CREB and CREB3 are transcription factors.
See CREB and CREB3
CREB3L1
CAMP responsive element binding protein 3 like 1, also known as OASIS, is a responsive element binding protein that in humans is encoded by the CREB3L1 gene.
See CREB and CREB3L1
CREB5
Cyclic AMP-responsive element-binding protein 5 is a protein that in humans is encoded by the CREB5 gene.
See CREB and CREB5
Cyclic adenosine monophosphate
Cyclic adenosine monophosphate (cAMP, cyclic AMP, or 3',5'-cyclic adenosine monophosphate) is a second messenger, or cellular signal occurring within cells, that is important in many biological processes.
See CREB and Cyclic adenosine monophosphate
Dentate gyrus
The dentate gyrus (DG) is part of the hippocampal formation in the temporal lobe of the brain, which also includes the hippocampus and the subiculum.
DNA
Deoxyribonucleic acid (DNA) is a polymer composed of two polynucleotide chains that coil around each other to form a double helix.
See CREB and DNA
DNA methylation
DNA methylation is a biological process by which methyl groups are added to the DNA molecule.
Drosophila melanogaster
Drosophila melanogaster is a species of fly (an insect of the order Diptera) in the family Drosophilidae.
See CREB and Drosophila melanogaster
Enhancer (genetics)
In genetics, an enhancer is a short (50–1500 bp) region of DNA that can be bound by proteins (activators) to increase the likelihood that transcription of a particular gene will occur.
See CREB and Enhancer (genetics)
Enkephalin
An enkephalin is a pentapeptide involved in regulating nociception (pain sensation) in the body.
Entrainment (chronobiology)
In the study of chronobiology, entrainment refers to the synchronization of a biological clock to an environmental cycle.
See CREB and Entrainment (chronobiology)
G protein-coupled receptor
G protein-coupled receptors (GPCRs), also known as seven-(pass)-transmembrane domain receptors, 7TM receptors, heptahelical receptors, serpentine receptors, and G protein-linked receptors (GPLR), form a large group of evolutionarily related proteins that are cell surface receptors that detect molecules outside the cell and activate cellular responses.
See CREB and G protein-coupled receptor
Gene
In biology, the word gene has two meanings.
See CREB and Gene
Huntington's disease
Huntington's disease (HD), also known as Huntington's chorea, is an incurable neurodegenerative disease that is mostly inherited.
See CREB and Huntington's disease
Intrinsically photosensitive retinal ganglion cell
Intrinsically photosensitive retinal ganglion cells (ipRGCs), also called photosensitive retinal ganglion cells (pRGC), or melanopsin-containing retinal ganglion cells (mRGCs), are a type of neuron in the retina of the mammalian eye.
See CREB and Intrinsically photosensitive retinal ganglion cell
Leucine zipper
A leucine zipper (or leucine scissors) is a common three-dimensional structural motif in proteins.
Long-term memory
Long-term memory (LTM) is the stage of the Atkinson–Shiffrin memory model in which informative knowledge is held indefinitely.
Long-term potentiation
In neuroscience, long-term potentiation (LTP) is a persistent strengthening of synapses based on recent patterns of activity.
See CREB and Long-term potentiation
Major depressive disorder
Major depressive disorder (MDD), also known as clinical depression, is a mental disorder characterized by at least two weeks of pervasive low mood, low self-esteem, and loss of interest or pleasure in normally enjoyable activities.
See CREB and Major depressive disorder
Melanopsin
Melanopsin is a type of photopigment belonging to a larger family of light-sensitive retinal proteins called opsins and encoded by the gene Opn4.
Michael E. Greenberg
Michael Greenberg (born May 25, 1954 in Miami Beach, Florida) is an American neuroscientist who specializes in molecular neurobiology.
See CREB and Michael E. Greenberg
Neuron
A neuron, neurone, or nerve cell is an excitable cell that fires electric signals called action potentials across a neural network in the nervous system.
See CREB and Neuron
Neuropeptide
Neuropeptides are chemical messengers made up of small chains of amino acids that are synthesized and released by neurons.
Neuroplasticity
Neuroplasticity, also known as neural plasticity or brain plasticity, is the ability of neural networks in the brain to change through growth and reorganization.
NMDA receptor
The N-methyl-D-aspartate receptor (also known as the NMDA receptor or NMDAR), is a glutamate receptor and predominantly Ca2+ ion channel found in neurons.
Norepinephrine
Norepinephrine (NE), also called noradrenaline (NA) or noradrenalin, is an organic chemical in the catecholamine family that functions in the brain and body as a hormone, neurotransmitter and neuromodulator.
PER2
PER2 is a protein in mammals encoded by the PER2 gene. CREB and PER2 are transcription factors.
See CREB and PER2
Period (gene)
Period (per) is a gene located on the X chromosome of Drosophila melanogaster.
Period circadian protein homolog 1
Period circadian protein homolog 1 is a protein in humans that is encoded by the PER1 gene. CREB and Period circadian protein homolog 1 are transcription factors.
See CREB and Period circadian protein homolog 1
Promoter (genetics)
In genetics, a promoter is a sequence of DNA to which proteins bind to initiate transcription of a single RNA transcript from the DNA downstream of the promoter.
See CREB and Promoter (genetics)
Protein c-Fos
Protein c-Fos is a proto-oncogene that is the human homolog of the retroviral oncogene v-fos. CREB and Protein c-Fos are Addiction and transcription factors.
Protein kinase
A protein kinase is a kinase which selectively modifies other proteins by covalently adding phosphates to them (phosphorylation) as opposed to kinases which modify lipids, carbohydrates, or other molecules.
Protein kinase A
In cell biology, protein kinase A (PKA) is a family of serine-threonine kinase whose activity is dependent on cellular levels of cyclic AMP (cAMP).
Protein kinase C
In cell biology, Protein kinase C, commonly abbreviated to PKC (EC 2.7.11.13), is a family of protein kinase enzymes that are involved in controlling the function of other proteins through the phosphorylation of hydroxyl groups of serine and threonine amino acid residues on these proteins, or a member of this family.
Psychological dependence
Psychological dependence is a cognitive disorder that involves emotional–motivational withdrawal symptoms – such as anxiety or anhedonia – upon cessation of prolonged drug abuse or certain repetitive behaviors.
See CREB and Psychological dependence
Response element
Response elements are short sequences of DNA within a gene promoter or enhancer region that are able to bind specific transcription factors and regulate transcription of genes.
Retinohypothalamic tract
In neuroanatomy, the retinohypothalamic tract (RHT) is a photic neural input pathway involved in the circadian rhythms of mammals.
See CREB and Retinohypothalamic tract
Rubinstein–Taybi syndrome
Rubinstein–Taybi syndrome (RTS) is a rare genetic condition characterized by short stature, moderate to severe learning difficulties, distinctive facial features, and broad thumbs and first toes.
See CREB and Rubinstein–Taybi syndrome
Second messenger system
Second messengers are intracellular signaling molecules released by the cell in response to exposure to extracellular signaling molecules—the first messengers.
See CREB and Second messenger system
Serotonin
Serotonin or 5-hydroxytryptamine (5-HT) is a monoamine neurotransmitter.
Somatostatin
Somatostatin, also known as growth hormone-inhibiting hormone (GHIH) or by several other names, is a peptide hormone that regulates the endocrine system and affects neurotransmission and cell proliferation via interaction with G protein-coupled somatostatin receptors and inhibition of the release of numerous secondary hormones.
Spatial memory
In cognitive psychology and neuroscience, spatial memory is a form of memory responsible for the recording and recovery of information needed to plan a course to a location and to recall the location of an object or the occurrence of an event.
Suprachiasmatic nucleus
The suprachiasmatic nucleus or nuclei (SCN) is a small region of the brain in the hypothalamus, situated directly above the optic chiasm.
See CREB and Suprachiasmatic nucleus
Transcription (biology)
Transcription is the process of copying a segment of DNA into RNA.
See CREB and Transcription (biology)
Transcription factor
In molecular biology, a transcription factor (TF) (or sequence-specific DNA-binding factor) is a protein that controls the rate of transcription of genetic information from DNA to messenger RNA, by binding to a specific DNA sequence. CREB and transcription factor are transcription factors.
See CREB and Transcription factor
Tyrosine hydroxylase
Tyrosine hydroxylase or tyrosine 3-monooxygenase is the enzyme responsible for catalyzing the conversion of the amino acid L-tyrosine to L-3,4-dihydroxyphenylalanine (L-DOPA).
See CREB and Tyrosine hydroxylase
VGF
VGF or VGF nerve growth factor inducible is a secreted protein and neuropeptide precursor that may play a role in regulating energy homeostasis, metabolism and synaptic plasticity.
See CREB and VGF
References
Also known as CAMP response binding element protein, CAMP response element, CAMP response element binding protein, CAMP response element-binding, CAMP response element-binding protein, CAMP-response element, CREB system, Cyclic AMP response element-binding protein, Cyclic amp response element-binding protein a, Pcreb.