IONIS-GCCRRx

IONIS-GCCRRx, also known as ISIS-426115, is an antiglucocorticoid which is under development by Ionis Pharmaceuticals (formerly Isis Pharmaceuticals) for the treatment of diabetes mellitus type 2. ^[1]

Antiglucocorticoid

An antiglucocorticoid is a drug which reduces glucocorticoid activity in the body. IONIS-GCCRRx and antiglucocorticoid are antiglucocorticoids.

See IONIS-GCCRRx and Antiglucocorticoid

Clinical trial

Clinical trials are prospective biomedical or behavioral research studies on human participants designed to answer specific questions about biomedical or behavioral interventions, including new treatments (such as novel vaccines, drugs, dietary choices, dietary supplements, and medical devices) and known interventions that warrant further study and comparison.

See IONIS-GCCRRx and Clinical trial

Cushing's syndrome

Cushing's syndrome is a collection of signs and symptoms due to prolonged exposure to glucocorticoids such as cortisol.

See IONIS-GCCRRx and Cushing's syndrome

Glucocorticoid receptor

The glucocorticoid receptor (GR or GCR) also known as NR3C1 (nuclear receptor subfamily 3, group C, member 1) is the receptor to which cortisol and other glucocorticoids bind.

See IONIS-GCCRRx and Glucocorticoid receptor

Oligonucleotide

Oligonucleotides are short DNA or RNA molecules, oligomers, that have a wide range of applications in genetic testing, research, and forensics.

See IONIS-GCCRRx and Oligonucleotide

Type 2 diabetes

Type 2 diabetes (T2D), formerly known as adult-onset diabetes, is a form of diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.

See IONIS-GCCRRx and Type 2 diabetes

References

[1] https://en.wikipedia.org/wiki/IONIS-GCCRRx

Also known as IONIS GCCR Rx, IONIS GCCR-Rx, IONIS GCCRRx, IONIS-GCCR Rx, IONIS-GCCR-Rx, IONISGCCR Rx, IONISGCCR-Rx, IONISGCCRRx, ISIS 426,115, ISIS 426115, ISIS GCCR Rx, ISIS GCCR-Rx, ISIS-426,115, ISIS-426115, ISIS-GCCR Rx, ISIS-GCCR-Rx, ISIS-GCCRRx, ISIS426115, ISISGCCR-Rx, ISISGCCRRx.

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IONIS-GCCRRx

Table of Contents

Antiglucocorticoid

Clinical trial

Cushing's syndrome

Glucocorticoid receptor

Oligonucleotide

Type 2 diabetes

See also

Antiglucocorticoids

Antisense RNA

Drugs with undisclosed chemical structures

Experimental diabetes drugs

Therapeutic gene modulation

References