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Multiomics

Index Multiomics

Multiomics, multi-omics, integrative omics, "panomics" or "pan-omics" is a biological analysis approach in which the data sets are multiple "omes", such as the genome, proteome, transcriptome, epigenome, metabolome, and microbiome (i.e., a meta-genome and/or meta-transcriptome, depending upon how it is sequenced); in other words, the use of multiple omics technologies to study life in a concerted way. [1]

Table of Contents

  1. 50 relations: Alternative splicing, American Society of Clinical Oncology, ATAC-seq, Autoimmune disease, Big data, Bioconductor, Biological network, Biomarker, Bisulfite sequencing, Breast cancer, Chikungunya, Copy number variation, DisGeNET, Epigenome, Escherichia coli, Genome, Gourd, High throughput biology, Hologenomics, Human Microbiome Project, Immune system, List of omics topics in biology, Machine learning, Maize, Mass cytometry, Metabolome, Metagenomics, Metatranscriptomics, Microbiome, Microbiota, Multi-Omics Profiling Expression Database, Network medicine, Non-coding DNA, Non-communicable disease, Omics, Pan-genome, Pancreas, Partial least squares regression, Post-translational modification, Proteome, Shingles, Single-cell analysis, Single-nucleotide polymorphism, Soybean, Systems biology, The Cancer Genome Atlas, Transcriptome, Type 2 diabetes, Vaccine, Zika virus.

  2. Biology theories

Alternative splicing

Alternative splicing, or alternative RNA splicing, or differential splicing, is an alternative splicing process during gene expression that allows a single gene to produce different splice variants.

See Multiomics and Alternative splicing

American Society of Clinical Oncology

The American Society of Clinical Oncology (ASCO) is a professional organization representing physicians of all oncology sub-specialties who care for people with cancer.

See Multiomics and American Society of Clinical Oncology

ATAC-seq

ATAC-seq (Assay for Transposase-Accessible Chromatin using sequencing) is a technique used in molecular biology to assess genome-wide chromatin accessibility.

See Multiomics and ATAC-seq

Autoimmune disease

An autoimmune disease is a condition that results from an anomalous response of the adaptive immune system, wherein it mistakenly targets and attacks healthy, functioning parts of the body as if they were foreign organisms.

See Multiomics and Autoimmune disease

Big data

Big data primarily refers to data sets that are too large or complex to be dealt with by traditional data-processing application software.

See Multiomics and Big data

Bioconductor

Bioconductor is a free, open source and open development software project for the analysis and comprehension of genomic data generated by wet lab experiments in molecular biology.

See Multiomics and Bioconductor

Biological network

A biological network is a method of representing systems as complex sets of binary interactions or relations between various biological entities.

See Multiomics and Biological network

Biomarker

In biomedical contexts, a biomarker, or biological marker, is a measurable indicator of some biological state or condition.

See Multiomics and Biomarker

Bisulfite sequencing

Bisulfite sequencing (also known as bisulphite sequencing) is the use of bisulfite treatment of DNA before routine sequencing to determine the pattern of methylation. Multiomics and bisulfite sequencing are molecular biology.

See Multiomics and Bisulfite sequencing

Breast cancer

Breast cancer is a cancer that develops from breast tissue.

See Multiomics and Breast cancer

Chikungunya

Chikungunya is an infection caused by the Chikungunya virus (CHIKV).

See Multiomics and Chikungunya

Copy number variation

Copy number variation (CNV) is a phenomenon in which sections of the genome are repeated and the number of repeats in the genome varies between individuals. Multiomics and Copy number variation are molecular biology.

See Multiomics and Copy number variation

DisGeNET

DisGeNET is a discovery platform designed to address a variety of questions concerning the genetic underpinning of human diseases.

See Multiomics and DisGeNET

Epigenome

In biology, the epigenome of an organism is the collection of chemical changes to its DNA and histone proteins that affects when, where, and how the DNA is expressed; these changes can be passed down to an organism's offspring via transgenerational stranded epigenetic inheritance.

See Multiomics and Epigenome

Escherichia coli

Escherichia coliWells, J. C. (2000) Longman Pronunciation Dictionary.

See Multiomics and Escherichia coli

Genome

In the fields of molecular biology and genetics, a genome is all the genetic information of an organism.

See Multiomics and Genome

Gourd

Gourds include the fruits of some flowering plant species in the family Cucurbitaceae, particularly Cucurbita and Lagenaria.

See Multiomics and Gourd

High throughput biology

High throughput biology (or high throughput cell biology) is the use of automation equipment with classical cell biology techniques to address biological questions that are otherwise unattainable using conventional methods.

See Multiomics and High throughput biology

Hologenomics

Hologenomics is the omics study of hologenomes.

See Multiomics and Hologenomics

Human Microbiome Project

The Human Microbiome Project (HMP) was a United States National Institutes of Health (NIH) research initiative to improve understanding of the microbiota involved in human health and disease.

See Multiomics and Human Microbiome Project

Immune system

The immune system is a network of biological systems that protects an organism from diseases.

See Multiomics and Immune system

List of omics topics in biology

Inspired by the terms genome and genomics, other words to describe complete biological datasets, mostly sets of biomolecules originating from one organism, have been coined with the suffix -ome and -omics.

See Multiomics and List of omics topics in biology

Machine learning

Machine learning (ML) is a field of study in artificial intelligence concerned with the development and study of statistical algorithms that can learn from data and generalize to unseen data and thus perform tasks without explicit instructions.

See Multiomics and Machine learning

Maize

Maize (Zea mays), also known as corn in North American English, is a tall stout grass that produces cereal grain.

See Multiomics and Maize

Mass cytometry

Mass cytometry is a mass spectrometry technique based on inductively coupled plasma mass spectrometry and time of flight mass spectrometry used for the determination of the properties of cells (cytometry).

See Multiomics and Mass cytometry

Metabolome

The metabolome refers to the complete set of small-molecule chemicals found within a biological sample.

See Multiomics and Metabolome

Metagenomics

Metagenomics is the study of genetic material recovered directly from environmental or clinical samples by a method called sequencing.

See Multiomics and Metagenomics

Metatranscriptomics

Metatranscriptomics is the set of techniques used to study gene expression of microbes within natural environments, i.e., the metatranscriptome.

See Multiomics and Metatranscriptomics

Microbiome

A microbiome is the community of microorganisms that can usually be found living together in any given habitat.

See Multiomics and Microbiome

Microbiota

Microbiota are the range of microorganisms that may be commensal, mutualistic, or pathogenic found in and on all multicellular organisms, including plants.

See Multiomics and Microbiota

Multi-Omics Profiling Expression Database

The Multi-Omics Profiling Expression Database (MOPED) was an expanding multi-omics resource that supports rapid browsing of transcriptomics and proteomics information from publicly available studies on model organisms and humans.

See Multiomics and Multi-Omics Profiling Expression Database

Network medicine

Network medicine is the application of network science towards identifying, preventing, and treating diseases.

See Multiomics and Network medicine

Non-coding DNA

Non-coding DNA (ncDNA) sequences are components of an organism's DNA that do not encode protein sequences.

See Multiomics and Non-coding DNA

Non-communicable disease

A non-communicable disease (NCD) is a disease that is not transmissible directly from one person to another.

See Multiomics and Non-communicable disease

Omics

The branches of science known informally as omics are various disciplines in biology whose names end in the suffix -omics, such as genomics, proteomics, metabolomics, metagenomics, phenomics and transcriptomics.

See Multiomics and Omics

Pan-genome

In the fields of molecular biology and genetics, a pan-genome (pangenome or supragenome) is the entire set of genes from all strains within a clade.

See Multiomics and Pan-genome

Pancreas

The pancreas is an organ of the digestive system and endocrine system of vertebrates.

See Multiomics and Pancreas

Partial least squares regression

Partial least squares (PLS) regression is a statistical method that bears some relation to principal components regression; instead of finding hyperplanes of maximum variance between the response and independent variables, it finds a linear regression model by projecting the predicted variables and the observable variables to a new space.

See Multiomics and Partial least squares regression

Post-translational modification

In molecular biology, post-translational modification (PTM) is the covalent process of changing proteins following protein biosynthesis.

See Multiomics and Post-translational modification

Proteome

The proteome is the entire set of proteins that is, or can be, expressed by a genome, cell, tissue, or organism at a certain time.

See Multiomics and Proteome

Shingles

Shingles, also known as herpes zoster, is a viral disease characterized by a painful skin rash with blisters in a localized area.

See Multiomics and Shingles

Single-cell analysis

In the field of cellular biology, single-cell analysis and subcellular analysis is the study of genomics, transcriptomics, proteomics, metabolomics and cell–cell interactions at the single cell level.

See Multiomics and Single-cell analysis

Single-nucleotide polymorphism

In genetics and bioinformatics, a single-nucleotide polymorphism (SNP; plural SNPs) is a germline substitution of a single nucleotide at a specific position in the genome. Multiomics and single-nucleotide polymorphism are molecular biology.

See Multiomics and Single-nucleotide polymorphism

Soybean

The soybean, soy bean, or soya bean (Glycine max) is a species of legume native to East Asia, widely grown for its edible bean, which has numerous uses.

See Multiomics and Soybean

Systems biology

Systems biology is the computational and mathematical analysis and modeling of complex biological systems.

See Multiomics and Systems biology

The Cancer Genome Atlas

The Cancer Genome Atlas (TCGA) is a project to catalogue the genomic alterations responsible for cancer using genome sequencing and bioinformatics.

See Multiomics and The Cancer Genome Atlas

Transcriptome

The transcriptome is the set of all RNA transcripts, including coding and non-coding, in an individual or a population of cells.

See Multiomics and Transcriptome

Type 2 diabetes

Type 2 diabetes (T2D), formerly known as adult-onset diabetes, is a form of diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.

See Multiomics and Type 2 diabetes

Vaccine

A vaccine is a biological preparation that provides active acquired immunity to a particular infectious or malignant disease.

See Multiomics and Vaccine

Zika virus

Zika virus (ZIKV; pronounced or) is a member of the virus family Flaviviridae.

See Multiomics and Zika virus

See also

Biology theories

References

[1] https://en.wikipedia.org/wiki/Multiomics

Also known as Multi-omics, Pan-omics, Panomics.