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16α-Hydroxyandrostenedione

Index 16α-Hydroxyandrostenedione

16α-Hydroxyandrostenedione (16α-OH-A4), also known as 16α-hydroxyandrost-4-ene-3,17-dione, is an endogenous and naturally occurring steroid and metabolic intermediate in the biosynthesis of estriol during pregnancy. [1]

16 relations: Androstenedione, Aromatase, Biosynthesis, Dehydroepiandrosterone, Endogeny (biology), Estriol, Metabolic intermediate, Natural product, Pregnancy, Steroid, Sulfatase, 11β-Hydroxyandrostenedione, 15α-Hydroxy-DHEA, 16α-Hydroxy-DHEA sulfate, 16α-Hydroxyestrone, 17β-Hydroxysteroid dehydrogenase.

Androstenedione

Androstenedione, or 4-androstenedione (abbreviated as A4 or Δ4-dione), also known as androst-4-ene-3,17-dione, is an endogenous weak androgen steroid hormone and intermediate in the biosynthesis of estrone and of testosterone from dehydroepiandrosterone (DHEA).

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Aromatase

Aromatase, also called estrogen synthetase or estrogen synthase, is an enzyme responsible for a key step in the biosynthesis of estrogens.

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Biosynthesis

Biosynthesis (also called anabolism) is a multi-step, enzyme-catalyzed process where substrates are converted into more complex products in living organisms.

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Dehydroepiandrosterone

Dehydroepiandrosterone (DHEA), also known as androstenolone, is an endogenous steroid hormone.

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Endogeny (biology)

Endogenous substances and processes are those that originate from within an organism, tissue, or cell.

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Estriol

Estriol (E3), also spelled oestriol, is a steroid, a weak estrogen, and a minor female sex hormone.

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Metabolic intermediate

Metabolic intermediates are molecules which are the precursors or metabolites of biologically significant molecules.

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Natural product

A natural product is a chemical compound or substance produced by a living organism—that is, found in nature.

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Pregnancy

Pregnancy, also known as gestation, is the time during which one or more offspring develops inside a woman.

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Steroid

A steroid is a biologically active organic compound with four rings arranged in a specific molecular configuration.

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Sulfatase

Sulfatases are enzymes of the esterase class that catalyze the hydrolysis of sulfate esters.

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11β-Hydroxyandrostenedione

11β-Hydroxyandrostenedione (11β-OHA4), also known as 11β-hydroxyandrost-4-ene-3,17-dione, is an endogenous, naturally occurring steroid and androgen prohormone that is produced primarily, if not exclusively, in the adrenal glands.

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15α-Hydroxy-DHEA

15α-Hydroxydehydroepiandrosterone, abbreviated as 15α-hydroxy-DHEA or 15α-OH-DHEA, is an endogenous metabolite of dehydroepiandrosterone (DHEA).

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16α-Hydroxy-DHEA sulfate

16α-Hydroxydehydroepiandrosterone sulfate (16α-OH-DHEA-S), also known as 16α-hydroxy-17-oxoandrost-5-en-3β-yl sulfate, is an endogenous, naturally occurring steroid and a metabolic intermediate in the production of estriol from dehydroepiandrosterone (DHEA) during pregnancy.

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16α-Hydroxyestrone

16α-Hydroxyestrone (16α-OH-E1), or hydroxyestrone, also known as estra-1,3,5(10)-trien-3,16α-diol-17-one, is an endogenous steroidal estrogen and a major metabolite of estrone, as well as an intermediate in the biosynthesis of estriol.

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17β-Hydroxysteroid dehydrogenase

17β-Hydroxysteroid dehydrogenases (17β-HSD, HSD17B), also 17-ketosteroid reductases (17-KSR), are a group of alcohol oxidoreductases which catalyze the reduction of 17-ketosteroids and the dehydrogenation of 17β-hydroxysteroids in steroidogenesis and steroid metabolism.

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Redirects here:

16-HA4, 16-Hydroxy-4-androstene-3,17-dione, 16-Hydroxy-4-androstenedione, 16-Hydroxyandrost-4-ene-3,17-dione, 16-Hydroxyandrost-4-enedione, 16-Hydroxyandrostenedione, 16-OH-A4, 16-OHA4, 16-hydroxy-4-androstene-3,17-dione, 16-hydroxy-4-androstenedione, 16-hydroxyandrost-4-ene-3,17-dione, 16-hydroxyandrost-4-enedione, 16-hydroxyandrostenedione, 16α-HA4, 16α-Hydroxy-4-androstene-3,17-dione, 16α-Hydroxy-4-androstenedione, 16α-Hydroxyandrost-4-ene-3,17-dione, 16α-Hydroxyandrost-4-enedione, 16α-OH-A4, 16α-OHA4, 16α-hydroxy-4-androstene-3,17-dione, 16α-hydroxy-4-androstenedione, 16α-hydroxyandrost-4-ene-3,17-dione, 16α-hydroxyandrost-4-enedione, 16α-hydroxyandrostenedione.

References

[1] https://en.wikipedia.org/wiki/16α-Hydroxyandrostenedione

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