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14 relations: Amine, Anticoagulant, EC50, Estradiol, Estrogen, Estrogen receptor alpha, Estrogen receptor beta, Hydroxy group, Ligand (biochemistry), Organic compound, Potency (pharmacology), Steroid, Structural analog, 17β-Aminoestrogen.
Amine
In organic chemistry, amines are compounds and functional groups that contain a basic nitrogen atom with a lone pair.
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Anticoagulant
Anticoagulants, commonly referred to as blood thinners, are chemical substances that prevent or reduce coagulation of blood, prolonging the clotting time.
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EC50
Half maximal effective concentration (EC50) refers to the concentration of a drug, antibody or toxicant which induces a response halfway between the baseline and maximum after a specified exposure time.
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Estradiol
Estradiol (E2), also spelled oestradiol, is an estrogen steroid hormone and the major female sex hormone.
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Estrogen
Estrogen, or oestrogen, is the primary female sex hormone.
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Estrogen receptor alpha
Estrogen receptor alpha (ERα), also known as NR3A1 (nuclear receptor subfamily 3, group A, member 1), is one of two main types of estrogen receptor, a nuclear receptor that is activated by the sex hormone estrogen.
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Estrogen receptor beta
Estrogen receptor beta (ER-β), also known as NR3A2 (nuclear receptor subfamily 3, group A, member 2), is one of two main types of estrogen receptor, a nuclear receptor which is activated by the sex hormone estrogen.
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Hydroxy group
A hydroxy or hydroxyl group is the entity with the formula OH.
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Ligand (biochemistry)
In biochemistry and pharmacology, a ligand is a substance that forms a complex with a biomolecule to serve a biological purpose.
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Organic compound
In chemistry, an organic compound is generally any chemical compound that contains carbon.
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Potency (pharmacology)
In the field of pharmacology, potency is a measure of drug activity expressed in terms of the amount required to produce an effect of given intensity.
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Steroid
A steroid is a biologically active organic compound with four rings arranged in a specific molecular configuration.
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Structural analog
A structural analog, also known as a chemical analog or simply an analog, is a compound having a structure similar to that of another compound, but differing from it in respect to a certain component.
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17β-Aminoestrogen
17β-Aminoestrogens are a group of synthetic, steroidal estrogens derived from estradiol which have an amine substitution in place of the hydroxyl group at the C17β position.
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17-Amino-estradiol, 17-Aminoestra-1,3,5(10)-trien-3-ol, 17-Aminoestradiol, 17-amino-estradiol, 17-aminoestra-1,3,5(10)-trien-3-ol, 17-aminoestradiol, 17β-Amino-estradiol, 17β-Aminoestra-1,3,5(10)-trien-3-ol, 17β-Aminoestradiol, 17β-amino-estradiol, 17β-aminoestra-1,3,5(10)-trien-3-ol, 17β-aminoestradiol, Amino-estradiol.
