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32 relations: Adenosine diphosphate, Adenosine triphosphate, Caucasian race, Clopidogrel, Cystic fibrosis, G protein–coupled receptor, Gi alpha subunit, Gq alpha subunit, Gs alpha subunit, LPAR4, LPAR6, Lysophosphatidic acid, Myocardial infarction, Nucleotide, Orphan receptor, P2RY1, P2RY10, P2RY11, P2RY13, P2RY14, P2RY2, P2RY4, P2RY6, P2RY8, P2Y12, Polymorphism (biology), Purinergic receptor, Thienopyridine, Tissue (biology), Uridine diphosphate, Uridine diphosphate glucose, Uridine triphosphate.
Adenosine diphosphate
Adenosine diphosphate (ADP), also known as adenosine pyrophosphate (APP), is an important organic compound in metabolism and is essential to the flow of energy in living cells.
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Adenosine triphosphate
Adenosine triphosphate (ATP) is a complex organic chemical that participates in many processes.
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Caucasian race
The Caucasian race (also Caucasoid or Europid) is a grouping of human beings historically regarded as a biological taxon, which, depending on which of the historical race classifications used, have usually included some or all of the ancient and modern populations of Europe, the Caucasus, Asia Minor, North Africa, the Horn of Africa, Western Asia, Central Asia and South Asia.
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Clopidogrel
Clopidogrel, sold as the brandname Plavix among others, is an antiplatelet medication that is used to reduce the risk of heart disease and stroke in those at high risk.
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Cystic fibrosis
Cystic fibrosis (CF) is a genetic disorder that affects mostly the lungs, but also the pancreas, liver, kidneys, and intestine.
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G protein–coupled receptor
G protein–coupled receptors (GPCRs), also known as seven-(pass)-transmembrane domain receptors, 7TM receptors, heptahelical receptors, serpentine receptor, and G protein–linked receptors (GPLR), constitute a large protein family of receptors that detect molecules outside the cell and activate internal signal transduction pathways and, ultimately, cellular responses.
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Gi alpha subunit
Gi alpha subunit (Gαi, or Gi/G0 or Gi protein) is a heterotrimeric G protein subunit that inhibits the production of cAMP from ATP.
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Gq alpha subunit
Gq protein (Gαq, or Gq/11) is a heterotrimeric G protein subunit that activates phospholipase C (PLC).
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Gs alpha subunit
The Gs alpha subunit (Gαs, Gsα, or Gs protein) is a heterotrimeric G protein subunit that activates the cAMP-dependent pathway by activating adenylyl cyclase.
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LPAR4
Lysophosphatidic acid receptor 4 also known as LPA4 is a protein that in humans is encoded by the LPAR4 gene.
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LPAR6
Lysophosphatidic acid receptor 6 also known as LPA6, P2RY5, and GPR87, is a protein that in humans is encoded by the LPAR6 gene.
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Lysophosphatidic acid
Lysophosphatidic acid (LPA) is a phospholipid derivative that can act as a signaling molecule.
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Myocardial infarction
Myocardial infarction (MI), commonly known as a heart attack, occurs when blood flow decreases or stops to a part of the heart, causing damage to the heart muscle.
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Nucleotide
Nucleotides are organic molecules that serve as the monomer units for forming the nucleic acid polymers deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), both of which are essential biomolecules within all life-forms on Earth.
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Orphan receptor
In biochemistry, an orphan receptor is a protein that has a similar structure to other identified receptors but whose endogenous ligand has not yet been identified.
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P2RY1
P2Y purinoceptor 1 is a protein that in humans is encoded by the P2RY1 gene.
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P2RY10
Putative P2Y purinoceptor 10 is a protein that, in humans, is encoded by the P2RY10 gene.
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P2RY11
P2Y purinoceptor 11 is a protein that in humans is encoded by the P2RY11 gene.
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P2RY13
P2Y purinoceptor 13 is a protein that in humans is encoded by the P2RY13 gene.
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P2RY14
P2Y purinoceptor 14 is a protein that in humans is encoded by the P2RY14 gene.
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P2RY2
P2Y purinoceptor 2 is a protein that in humans is encoded by the P2RY2 gene.
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P2RY4
P2Y purinoceptor 4 is a protein that in humans is encoded by the P2RY4 gene.
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P2RY6
P2Y purinoceptor 6 is a protein that in humans is encoded by the P2RY6 gene.
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P2RY8
P2Y purinoceptor 8 is a protein that in humans is encoded by the P2RY8 gene.
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P2Y12
In the field of purinergic signaling, the P2Y12 protein is found mainly but not exclusively on the surface of blood platelets, and is an important regulator in blood clotting.
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Polymorphism (biology)
Polymorphism in biology and zoology is the occurrence of two or more clearly different morphs or forms, also referred to as alternative phenotypes, in the population of a species.
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Purinergic receptor
Purinergic receptors, also known as purinoceptors, are a family of plasma membrane molecules that are found in almost all mammalian tissues.
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Thienopyridine
Thienopyridines are a class of selective, irreversible ADP receptor/P2Y12 inhibitors used for their anti-platelet activity.
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Tissue (biology)
In biology, tissue is a cellular organizational level between cells and a complete organ.
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Uridine diphosphate
Uridine diphosphate, abbreviated UDP, is a nucleotide diphosphate.
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Uridine diphosphate glucose
Uridine diphosphate glucose (uracil-diphosphate glucose, UDP-glucose) is a nucleotide sugar.
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Uridine triphosphate
Uridine-5'-triphosphate (UTP) is a pyrimidine nucleoside triphosphate, consisting of the organic base uracil linked to the 1' carbon of the ribose sugar, and esterified with tri-phosphoric acid at the 5' position.
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