32 relations: Adenosine diphosphate, Adenosine triphosphate, Caucasian race, Clopidogrel, Cystic fibrosis, G protein–coupled receptor, Gi alpha subunit, Gq alpha subunit, Gs alpha subunit, LPAR4, LPAR6, Lysophosphatidic acid, Myocardial infarction, Nucleotide, Orphan receptor, P2RY1, P2RY10, P2RY11, P2RY13, P2RY14, P2RY2, P2RY4, P2RY6, P2RY8, P2Y12, Polymorphism (biology), Purinergic receptor, Thienopyridine, Tissue (biology), Uridine diphosphate, Uridine diphosphate glucose, Uridine triphosphate.
Adenosine diphosphate (ADP), also known as adenosine pyrophosphate (APP), is an important organic compound in metabolism and is essential to the flow of energy in living cells.
Adenosine triphosphate (ATP) is a complex organic chemical that participates in many processes.
The Caucasian race (also Caucasoid or Europid) is a grouping of human beings historically regarded as a biological taxon, which, depending on which of the historical race classifications used, have usually included some or all of the ancient and modern populations of Europe, the Caucasus, Asia Minor, North Africa, the Horn of Africa, Western Asia, Central Asia and South Asia.
Clopidogrel, sold as the brandname Plavix among others, is an antiplatelet medication that is used to reduce the risk of heart disease and stroke in those at high risk.
Cystic fibrosis (CF) is a genetic disorder that affects mostly the lungs, but also the pancreas, liver, kidneys, and intestine.
G protein–coupled receptors (GPCRs), also known as seven-(pass)-transmembrane domain receptors, 7TM receptors, heptahelical receptors, serpentine receptor, and G protein–linked receptors (GPLR), constitute a large protein family of receptors that detect molecules outside the cell and activate internal signal transduction pathways and, ultimately, cellular responses.
Gi alpha subunit (Gαi, or Gi/G0 or Gi protein) is a heterotrimeric G protein subunit that inhibits the production of cAMP from ATP.
Gq protein (Gαq, or Gq/11) is a heterotrimeric G protein subunit that activates phospholipase C (PLC).
The Gs alpha subunit (Gαs, Gsα, or Gs protein) is a heterotrimeric G protein subunit that activates the cAMP-dependent pathway by activating adenylyl cyclase.
Lysophosphatidic acid receptor 4 also known as LPA4 is a protein that in humans is encoded by the LPAR4 gene.
Lysophosphatidic acid receptor 6 also known as LPA6, P2RY5, and GPR87, is a protein that in humans is encoded by the LPAR6 gene.
Lysophosphatidic acid (LPA) is a phospholipid derivative that can act as a signaling molecule.
Myocardial infarction (MI), commonly known as a heart attack, occurs when blood flow decreases or stops to a part of the heart, causing damage to the heart muscle.
Nucleotides are organic molecules that serve as the monomer units for forming the nucleic acid polymers deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), both of which are essential biomolecules within all life-forms on Earth.
In biochemistry, an orphan receptor is a protein that has a similar structure to other identified receptors but whose endogenous ligand has not yet been identified.
P2Y purinoceptor 1 is a protein that in humans is encoded by the P2RY1 gene.
Putative P2Y purinoceptor 10 is a protein that, in humans, is encoded by the P2RY10 gene.
P2Y purinoceptor 11 is a protein that in humans is encoded by the P2RY11 gene.
P2Y purinoceptor 13 is a protein that in humans is encoded by the P2RY13 gene.
P2Y purinoceptor 14 is a protein that in humans is encoded by the P2RY14 gene.
P2Y purinoceptor 2 is a protein that in humans is encoded by the P2RY2 gene.
P2Y purinoceptor 4 is a protein that in humans is encoded by the P2RY4 gene.
P2Y purinoceptor 6 is a protein that in humans is encoded by the P2RY6 gene.
P2Y purinoceptor 8 is a protein that in humans is encoded by the P2RY8 gene.
In the field of purinergic signaling, the P2Y12 protein is found mainly but not exclusively on the surface of blood platelets, and is an important regulator in blood clotting.
Polymorphism in biology and zoology is the occurrence of two or more clearly different morphs or forms, also referred to as alternative phenotypes, in the population of a species.
Purinergic receptors, also known as purinoceptors, are a family of plasma membrane molecules that are found in almost all mammalian tissues.
Thienopyridines are a class of selective, irreversible ADP receptor/P2Y12 inhibitors used for their anti-platelet activity.
In biology, tissue is a cellular organizational level between cells and a complete organ.
Uridine diphosphate, abbreviated UDP, is a nucleotide diphosphate.
Uridine diphosphate glucose (uracil-diphosphate glucose, UDP-glucose) is a nucleotide sugar.
Uridine-5'-triphosphate (UTP) is a pyrimidine nucleoside triphosphate, consisting of the organic base uracil linked to the 1' carbon of the ribose sugar, and esterified with tri-phosphoric acid at the 5' position.