32 relations: Allergic response, AP-1 transcription factor, Asthma, Autoimmunity, BATF (gene), Calcitonin gene-related peptide, Calcitriol, CD134, CD4, Cell biology, Cyclooxygenase, Cytokine, FOXP3, GATA3, Helminthiasis, Interleukin 10, Interleukin 2, Interleukin 21, Interleukin 25, Interleukin 33, Interleukin 4, Interleukin 9, Interleukin-1 family, IRF4, JAG2, Melanoma, NF-κB, STAT5, STAT6, T cell, Thymic stromal lymphopoietin, Transforming growth factor beta.
An allergic response is a hypersensitive immune reaction to a substance that normally is harmless or would not cause an immune response in everyone.
Activator protein 1 (AP-1) is a transcription factor that regulates gene expression in response to a variety of stimuli, including cytokines, growth factors, stress, and bacterial and viral infections.
Asthma is a common long-term inflammatory disease of the airways of the lungs.
Autoimmunity is the system of immune responses of an organism against its own healthy cells and tissues.
Basic leucine zipper transcription factor, ATF-like, also known as BATF, is a protein which in humans is encoded by the BATF gene.
Calcitonin gene-related peptide (CGRP) is a member of the calcitonin family of peptides, which in humans exists in two forms, α-CGRP and β-CGRP.
Calcitriol (INN), also called 1,25-dihydroxycholecalciferol, or 1alpha,25-dihydroxyvitamin D3, 1,25-dihydroxyvitamin D3 and other variants, is the hormonally active metabolite of vitamin D which has three hydroxyl groups.
Tumor necrosis factor receptor superfamily, member 4 (TNFRSF4), also known as CD134 and OX40 receptor, is a member of the TNFR-superfamily of receptors which is not constitutively expressed on resting naïve T cells, unlike CD28.
In molecular biology, CD4 (cluster of differentiation 4) is a glycoprotein found on the surface of immune cells such as T helper cells, monocytes, macrophages, and dendritic cells.
Cell biology (also called cytology, from the Greek κυτος, kytos, "vessel") is a branch of biology that studies the structure and function of the cell, the basic unit of life.
Cyclooxygenase (COX), officially known as prostaglandin-endoperoxide synthase (PTGS), is an enzyme (specifically, a family of isozymes) that is responsible for formation of prostanoids, including thromboxane and prostaglandins such as prostacyclin, from arachidonic acid.
Cytokines are a broad and loose category of small proteins (~5–20 kDa) that are important in cell signaling.
FOXP3 (forkhead box P3), also known as scurfin, is a protein involved in immune system responses.
GATA3 is a transcription factor that in humans is encoded by the GATA3 gene.
Helminthiasis (plural helminthiases), also known as worm infection, is any macroparasitic disease of humans and other animals in which a part of the body is infected with parasitic worms, known as helminths.
Interleukin 10 (IL-10), also known as human cytokine synthesis inhibitory factor (CSIF), is an anti-inflammatory cytokine.
Interleukin-2 (IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system.
Interleukin 21 (IL-21) is a protein that in humans is encoded by the IL21 gene.
Interleukin-25 (IL-25) – also known as interleukin-17E (IL-17E) – is a protein that in humans is encoded by the IL25 gene.
Interleukin 33 (IL-33) is a protein that in humans is encoded by the IL33 gene.
The interleukin 4 (IL4, IL-4) is a cytokine that induces differentiation of naive helper T cells (Th0 cells) to Th2 cells.
Interleukin 9, also known as IL-9, is a pleiotropic cytokine (cell signalling molecule) belonging to the group of interleukins.
The Interleukin-1 family (IL-1 family) is a group of 11 cytokines that plays a central role in the regulation of immune and inflammatory responses to infections or sterile insults.
Interferon regulatory factor 4 also known as MUM1 is a protein that in humans is encoded by the IRF4 gene, located at 6p25-p23.
Jagged-2 is a protein that in humans is encoded by the JAG2 gene.
Melanoma, also known as malignant melanoma, is a type of cancer that develops from the pigment-containing cells known as melanocytes.
NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) is a protein complex that controls transcription of DNA, cytokine production and cell survival.
Signal transducer and activator of transcription 5 (STAT5) refers to two highly related proteins, STAT5A and STAT5B, which are part of the seven-membered STAT family of proteins.
Signal transducer and activator of transcription 6 (STAT6) is a human gene.
A T cell, or T lymphocyte, is a type of lymphocyte (a subtype of white blood cell) that plays a central role in cell-mediated immunity.
Thymic stromal lymphopoietin (TSLP) is a protein belonging to the cytokine family.
Transforming growth factor beta (TGF-β) is a multifunctional cytokine belonging to the transforming growth factor superfamily that includes four different isoforms (TGF-β 1 to 4, HGNC symbols TGFB1, TGFB2, TGFB3, TGFB4) and many other signaling proteins produced by all white blood cell lineages.