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Sandmeyer reaction

Index Sandmeyer reaction

The Sandmeyer reaction is a chemical reaction used to synthesize aryl halides from aryl diazonium salts. [1]

53 relations: Aniline, Aromatic hydrocarbon, Aromaticity, Aryl halide, Aryl radical, Balz–Schiemann reaction, Benzonitrile, Bioavailability, Biphenyl, Bromoform, Chemical reaction, Chemical Reviews, Chemische Berichte, Chloroform, Copper fluoride, Cyanation, Cyanide, Denticity, Diazonium compound, Dibenzo-18-crown-6, Diiodomethane, Drug metabolism, Electrophile, Electrophilic aromatic substitution, Fluorobenzene, Flupentixol, Halide, Halogenation, Heterocyclic compound, Hydroxylation, Journal of Organic Chemistry, Journal of the American Chemical Society, Ligand, Lipophilicity, Ludwig Gattermann, Nitrosamine, Nitrosonium, Nitrous acid, Organobromine compound, Organochloride, Organoiodine compound, Phase-transfer catalyst, Phenanthroline, Phenol, Protonation, Pseudohalogen, Radical-nucleophilic aromatic substitution, Sodium nitrite, Tetrafluoroborate, Thiol, ..., Traugott Sandmeyer, Trifluoromethylation, Type II topoisomerase. Expand index (3 more) »

Aniline

Aniline is an organic compound with the formula C6H5NH2.

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Aromatic hydrocarbon

An aromatic hydrocarbon or arene (or sometimes aryl hydrocarbon) is a hydrocarbon with sigma bonds and delocalized pi electrons between carbon atoms forming a circle.

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Aromaticity

In organic chemistry, the term aromaticity is used to describe a cyclic (ring-shaped), planar (flat) molecule with a ring of resonance bonds that exhibits more stability than other geometric or connective arrangements with the same set of atoms.

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Aryl halide

In organic chemistry, an aryl halide (also known as haloarene or halogenoarene) is an aromatic compound in which one or more hydrogen atoms directly bonded to an aromatic ring are replaced by a halide.

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Aryl radical

An aryl radical in organic chemistry is a reactive intermediate and an arene compound incorporating one free radical carbon atom as part of the ring structure.

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Balz–Schiemann reaction

The Schiemann reaction (also called the Balz–Schiemann reaction) is a chemical reaction in which anilines (1) are transformed to aryl fluorides (3) via diazonium fluoroborates (2).

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Benzonitrile

Benzonitrile is the chemical compound with the formula, abbreviated PhCN.

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Bioavailability

In pharmacology, bioavailability (BA or F) is a subcategory of absorption and is the fraction of an administered dose of unchanged drug that reaches the systemic circulation, one of the principal pharmacokinetic properties of drugs.

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Biphenyl

Biphenyl (or diphenyl or phenylbenzene or 1,1′-biphenyl or lemonene) is an organic compound that forms colorless crystals.

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Bromoform

Bromoform (CHBr3) is a brominated organic solvent, colorless liquid at room temperature, with a high refractive index, very high density, and sweet odor is similar to that of chloroform.

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Chemical reaction

A chemical reaction is a process that leads to the transformation of one set of chemical substances to another.

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Chemical Reviews

Chemical Reviews is peer-reviewed scientific journal published twice per month by the American Chemical Society.

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Chemische Berichte

Chemische Berichte (usually abbreviated as Ber. or Chem. Ber.) was a German-language scientific journal of all disciplines of chemistry founded in 1868.

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Chloroform

Chloroform, or trichloromethane, is an organic compound with formula CHCl3.

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Copper fluoride

Copper fluoride could refer to.

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Cyanation

Cyanation is the attachment or substitution of a cyanide group on various substrates.

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Cyanide

A cyanide is a chemical compound that contains the group C≡N.

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Denticity

Denticity refers to the number of donor groups in a single ligand that bind to a central atom in a coordination complex.

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Diazonium compound

Diazonium compounds or diazonium salts are a group of organic compounds sharing a common functional group where R can be any organic group, such as an alkyl or an aryl, and X is an inorganic or organic anion, such as a halogen.

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Dibenzo-18-crown-6

Dibenzo-18-crown-6 is a benzannulated crown ether.

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Diiodomethane

Diiodomethane or methylene iodide, commonly abbreviated “MI”, is an organoiodine compound.

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Drug metabolism

Drug metabolism is the metabolic breakdown of drugs by living organisms, usually through specialized enzymatic systems.

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Electrophile

In organic chemistry, an electrophile is a reagent attracted to electrons.

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Electrophilic aromatic substitution

Electrophilic aromatic substitution is an organic reaction in which an atom that is attached to an aromatic system (usually hydrogen) is replaced by an electrophile.

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Fluorobenzene

Fluorobenzene is the chemical compound with the formula C6H5F, often abbreviated PhF.

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Flupentixol

Flupentixol (INN), also known as flupenthixol (former BAN), marketed under brand names such as Depixol and Fluanxol is a typical antipsychotic drug of the thioxanthene class.

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Halide

A halide is a binary phase, of which one part is a halogen atom and the other part is an element or radical that is less electronegative (or more electropositive) than the halogen, to make a fluoride, chloride, bromide, iodide, astatide, or theoretically tennesside compound.

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Halogenation

Halogenation is a chemical reaction that involves the addition of one or more halogens to a compound or material.

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Heterocyclic compound

A heterocyclic compound or ring structure is a cyclic compound that has atoms of at least two different elements as members of its ring(s).

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Hydroxylation

Hydroxylation is a chemical process that introduces a hydroxyl group (-OH) into an organic compound.

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Journal of Organic Chemistry

The Journal of Organic Chemistry, colloquially known as JOC or J Org, is a peer-reviewed scientific journal for original contributions of fundamental research in all branches of theory and practice in organic and bioorganic chemistry.

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Journal of the American Chemical Society

The Journal of the American Chemical Society (also known as JACS) is a weekly peer-reviewed scientific journal that was established in 1879 by the American Chemical Society.

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Ligand

In coordination chemistry, a ligand is an ion or molecule (functional group) that binds to a central metal atom to form a coordination complex.

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Lipophilicity

Lipophilicity (from Greek λίπος "fat" and φίλος "friendly"), refers to the ability of a chemical compound to dissolve in fats, oils, lipids, and non-polar solvents such as hexane or toluene.

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Ludwig Gattermann

Ludwig Gattermann (20 April 1860 – 20 June 1920) was a German chemist who contributed significantly to both organic and inorganic chemistry.

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Nitrosamine

Nitrosamines are chemical compounds of the chemical structure R1N(–R2)–N.

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Nitrosonium

The nitrosonium ion is NO+, in which the nitrogen atom is bonded to an oxygen atom with a bond order of 3, and the overall diatomic species bears a positive charge.

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Nitrous acid

Nitrous acid (molecular formula HNO2) is a weak and monobasic acid known only in solution and in the form of nitrite salts.

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Organobromine compound

Organobromine compounds, also called organobromides, are organic compounds that contain carbon bonded to bromine.

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Organochloride

An organochloride, organochlorine compound, chlorocarbon, or chlorinated hydrocarbon is an organic compound containing at least one covalently bonded atom of chlorine that has an effect on the chemical behavior of the molecule.

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Organoiodine compound

Organoiodine compounds are organic compounds that contain one or more carbon–iodine bonds.

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Phase-transfer catalyst

In chemistry, a phase-transfer catalyst or PTC is a catalyst that facilitates the migration of a reactant from one phase into another phase where reaction occurs.

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Phenanthroline

Phenanthroline (phen) is a heterocyclic organic compound.

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Phenol

Phenol, also known as phenolic acid, is an aromatic organic compound with the molecular formula C6H5OH.

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Protonation

In chemistry, protonation is the addition of a proton (H+) to an atom, molecule, or ion, forming the conjugate acid.

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Pseudohalogen

The pseudohalogens are polyatomic analogues of halogens, whose chemistry, resembling that of the true halogens, allows them to substitute for halogens in several classes of chemical compounds.

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Radical-nucleophilic aromatic substitution

Radical-nucleophilic aromatic substitution or SRN1 in organic chemistry is a type of substitution reaction in which a certain substituent on an aromatic compound is replaced by a nucleophile through an intermediary free radical species: The substituent X is a halide and nucleophiles can be sodium amide, an alkoxide or a carbon nucleophile such as an enolate.

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Sodium nitrite

Sodium nitrite is the inorganic compound with the chemical formula NaNO2.

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Tetrafluoroborate

Tetrafluoroborate is the anion BF4−.

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Thiol

Thiol is an organosulfur compound that contains a carbon-bonded sulfhydryl (R–SH) group (where R represents an alkyl or other organic substituent).

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Traugott Sandmeyer

Traugott Sandmeyer (September 15, 1854 – April 9, 1922) was a Swiss chemist after whom the Sandmeyer reaction, which he discovered 1884, was named.

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Trifluoromethylation

Trifluoromethylation in organic chemistry describes any organic reaction that introduces a trifluoromethyl group in an organic compound.

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Type II topoisomerase

Type II topoisomerases cut both strands of the DNA helix simultaneously in order to manage DNA tangles and supercoils.

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References

[1] https://en.wikipedia.org/wiki/Sandmeyer_reaction

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