Table of Contents
51 relations: ABL (gene), Adenomatous polyposis coli, ALS, Alzheimer's disease, Androgen receptor, Apoptosis, Autoimmune disease, Cell adhesion molecule, Cell cycle, Cell growth, Creutzfeldt–Jakob disease, Cyclin-dependent kinase, Cytokine, Dementia, Enzyme, Frontotemporal dementia, Gene, Heart failure, Huntington's disease, ICAM-1, Interleukin 8, Ischemia, Lupus, Malignancy, MOS (gene), Muscular dystrophy, MYB (gene), Myc, NF-κB, Nitric oxide, Oncogene, P-selectin, P53, Parkinson's disease, Prostaglandin, Proteasome, Protein c-Fos, Proteolysis, Proto-oncogene tyrosine-protein kinase Src, RAF kinase, Retinoblastoma, Rheumatoid arthritis, Sjögren syndrome, STAT3, Transcription factor, Transcription factor Jun, Tumor necrosis factor, Ubiquitin, VCAM-1, Ventricular hypertrophy, ... Expand index (1 more) »
ABL (gene)
Tyrosine-protein kinase ABL1 also known as ABL1 is a protein that, in humans, is encoded by the ABL1 gene (previous symbol ABL) located on chromosome 9.
Adenomatous polyposis coli
Adenomatous polyposis coli (APC) also known as deleted in polyposis 2.5 (DP2.5) is a protein that in humans is encoded by the APC gene.
See PSMD8 and Adenomatous polyposis coli
ALS
Amyotrophic lateral sclerosis (ALS), also known as motor neurone disease (MND) or Lou Gehrig's disease in the United States, is a rare, terminal neurodegenerative disorder that results in the progressive loss of both upper and lower motor neurons that normally control voluntary muscle contraction.
See PSMD8 and ALS
Alzheimer's disease
Alzheimer's disease (AD) is a neurodegenerative disease that usually starts slowly and progressively worsens, and is the cause of 60–70% of cases of dementia.
See PSMD8 and Alzheimer's disease
Androgen receptor
The androgen receptor (AR), also known as NR3C4 (nuclear receptor subfamily 3, group C, member 4), is a type of nuclear receptor that is activated by binding any of the androgenic hormones, including testosterone and dihydrotestosterone, in the cytoplasm and then translocating into the nucleus.
See PSMD8 and Androgen receptor
Apoptosis
Apoptosis (from falling off) is a form of programmed cell death that occurs in multicellular organisms and in some eukaryotic, single-celled microorganisms such as yeast.
Autoimmune disease
An autoimmune disease is a condition that results from an anomalous response of the adaptive immune system, wherein it mistakenly targets and attacks healthy, functioning parts of the body as if they were foreign organisms.
See PSMD8 and Autoimmune disease
Cell adhesion molecule
Cell adhesion molecules (CAMs) are a subset of cell surface proteins that are involved in the binding of cells with other cells or with the extracellular matrix (ECM), in a process called cell adhesion.
See PSMD8 and Cell adhesion molecule
Cell cycle
The cell cycle, or cell-division cycle, is the sequential series of events that take place in a cell that causes it to divide into two daughter cells.
Cell growth
Cell growth refers to an increase in the total mass of a cell, including both cytoplasmic, nuclear and organelle volume.
Creutzfeldt–Jakob disease
Creutzfeldt–Jakob disease (CJD), also known as subacute spongiform encephalopathy or neurocognitive disorder due to prion disease, is a fatal neurodegenerative disease.
See PSMD8 and Creutzfeldt–Jakob disease
Cyclin-dependent kinase
Cyclin-dependent kinases (CDKs) are a predominant group of serine/threonine protein kinases involved in the regulation of the cell cycle and its progression, ensuring the integrity and functionality of cellular machinery.
See PSMD8 and Cyclin-dependent kinase
Cytokine
Cytokines are a broad and loose category of small proteins (~5–25 kDa) important in cell signaling.
Dementia
Dementia is a syndrome associated with many neurodegenerative diseases, characterized by a general decline in cognitive abilities that affects a person's ability to perform everyday activities.
Enzyme
Enzymes are proteins that act as biological catalysts by accelerating chemical reactions.
See PSMD8 and Enzyme
Frontotemporal dementia
Frontotemporal dementia (FTD), also called frontotemporal degeneration disease or frontotemporal neurocognitive disorder, encompasses several types of dementia involving the progressive degeneration of the brain's frontal and temporal lobes.
See PSMD8 and Frontotemporal dementia
Gene
In biology, the word gene has two meanings.
See PSMD8 and Gene
Heart failure
Heart failure (HF), also known as congestive heart failure (CHF), is a syndrome caused by an impairment in the heart's ability to fill with and pump blood.
Huntington's disease
Huntington's disease (HD), also known as Huntington's chorea, is an incurable neurodegenerative disease that is mostly inherited.
See PSMD8 and Huntington's disease
ICAM-1
ICAM-1 (Intercellular Adhesion Molecule 1) also known as CD54 (Cluster of Differentiation 54) is a protein that in humans is encoded by the ICAM1 gene. PSMD8 and ICAM-1 are genes on human chromosome 19.
See PSMD8 and ICAM-1
Interleukin 8
Interleukin 8 (IL-8 or chemokine (C-X-C motif) ligand 8, CXCL8) is a chemokine produced by macrophages and other cell types such as epithelial cells, airway smooth muscle cells and endothelial cells.
Ischemia
Ischemia or ischaemia is a restriction in blood supply to any tissue, muscle group, or organ of the body, causing a shortage of oxygen that is needed for cellular metabolism (to keep tissue alive).
Lupus
Lupus, technically known as systemic lupus erythematosus (SLE), is an autoimmune disease in which the body's immune system mistakenly attacks healthy tissue in many parts of the body.
See PSMD8 and Lupus
Malignancy
Malignancy is the tendency of a medical condition to become progressively worse; the term is most familiar as a characterization of cancer.
MOS (gene)
Proto-oncogene serine/threonine-protein kinase mos is an enzyme that in humans is encoded by the MOS gene.
Muscular dystrophy
Muscular dystrophies (MD) are a genetically and clinically heterogeneous group of rare neuromuscular diseases that cause progressive weakness and breakdown of skeletal muscles over time.
See PSMD8 and Muscular dystrophy
MYB (gene)
Myb genes are part of a large gene family of transcription factors found in animals and plants.
Myc
Myc is a family of regulator genes and proto-oncogenes that code for transcription factors.
See PSMD8 and Myc
NF-κB
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a family of transcription factor protein complexes that controls transcription of DNA, cytokine production and cell survival. PSMD8 and NF-κB are genes on human chromosome 19.
See PSMD8 and NF-κB
Nitric oxide
Nitric oxide (nitrogen oxide or nitrogen monoxide) is a colorless gas with the formula.
Oncogene
An oncogene is a gene that has the potential to cause cancer.
P-selectin
P-selectin is a type-1 transmembrane protein that in humans is encoded by the SELP gene.
P53
p53, also known as Tumor protein P53, cellular tumor antigen p53 (UniProt name), or transformation-related protein 53 (TRP53) is a regulatory protein that is often mutated in human cancers.
See PSMD8 and P53
Parkinson's disease
Parkinson's disease (PD), or simply Parkinson's, is a long-term neurodegenerative disease of mainly the central nervous system that affects both the motor and non-motor systems of the body.
See PSMD8 and Parkinson's disease
Prostaglandin
Prostaglandins (PG) are a group of physiologically active lipid compounds called eicosanoids that have diverse hormone-like effects in animals.
Proteasome
Proteasomes are protein complexes which degrade ubiquitin-tagged proteins by proteolysis, a chemical reaction that breaks peptide bonds.
Protein c-Fos
Protein c-Fos is a proto-oncogene that is the human homolog of the retroviral oncogene v-fos.
Proteolysis
Proteolysis is the breakdown of proteins into smaller polypeptides or amino acids.
Proto-oncogene tyrosine-protein kinase Src
Proto-oncogene tyrosine-protein kinase Src, also known as proto-oncogene c-Src, or simply c-Src (cellular Src; pronounced "sarc", as it is short for sarcoma), is a non-receptor tyrosine kinase protein that in humans is encoded by the SRC gene.
See PSMD8 and Proto-oncogene tyrosine-protein kinase Src
RAF kinase
RAF kinases are a family of three serine/threonine-specific protein kinases that are related to retroviral oncogenes.
Retinoblastoma
Retinoblastoma (Rb) is a rare form of cancer that rapidly develops from the immature cells of a retina, the light-detecting tissue of the eye.
Rheumatoid arthritis
Rheumatoid arthritis (RA) is a long-term autoimmune disorder that primarily affects joints.
See PSMD8 and Rheumatoid arthritis
Sjögren syndrome
Sjögren syndrome or Sjögren's syndrome (SjS, SS) is a long-term autoimmune disease that primarily affects the body's exocrine glands, particularly the lacrimal and salivary glands.
See PSMD8 and Sjögren syndrome
STAT3
Signal transducer and activator of transcription 3 (STAT3) is a transcription factor which in humans is encoded by the STAT3 gene.
See PSMD8 and STAT3
Transcription factor
In molecular biology, a transcription factor (TF) (or sequence-specific DNA-binding factor) is a protein that controls the rate of transcription of genetic information from DNA to messenger RNA, by binding to a specific DNA sequence.
See PSMD8 and Transcription factor
Transcription factor Jun
Transcription factor Jun is a protein that in humans is encoded by the JUN gene.
See PSMD8 and Transcription factor Jun
Tumor necrosis factor
Tumor necrosis factor (TNF, cachexin, or cachectin; formerly known as tumor necrosis factor alpha, TNFα or TNF-α) is a cytokine and member of the TNF superfamily, which consists of various transmembrane proteins with a homologous TNF domain.
See PSMD8 and Tumor necrosis factor
Ubiquitin
Ubiquitin is a small (8.6 kDa) regulatory protein found in most tissues of eukaryotic organisms, i.e., it is found ''ubiquitously''.
VCAM-1
Vascular cell adhesion protein 1 also known as vascular cell adhesion molecule 1 (VCAM-1) or cluster of differentiation 106 (CD106) is a protein that in humans is encoded by the VCAM1 gene.
See PSMD8 and VCAM-1
Ventricular hypertrophy
Ventricular hypertrophy (VH) is thickening of the walls of a ventricle (lower chamber) of the heart.
See PSMD8 and Ventricular hypertrophy
Von Hippel–Lindau tumor suppressor
The Von Hippel–Lindau tumor suppressor also known as pVHL is a protein that, in humans, is encoded by the VHL gene.
See PSMD8 and Von Hippel–Lindau tumor suppressor
References
Also known as PSMD8 (gene).