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Index HLA-B27

Human leukocyte antigen (HLA) B27 (subtypes B*2701-2759) is a class I surface antigen encoded by the B locus in the major histocompatibility complex (MHC) on chromosome 6 and presents antigenic peptides (derived from self and non-self antigens) to T cells. [1]

29 relations: Ankylosing spondylitis, Antigen, Beta-2 microglobulin, Caucasian race, Chromosome 6, Cytotoxic T cell, Disease, Endoplasmic reticulum, European Bioinformatics Institute, Han Chinese, HLA-B, Human leukocyte antigen, Inflammatory bowel disease, Long-term nonprogressor, Major histocompatibility complex, Pathology, Peptide, Psoriasis, Psoriatic arthritis, Reactive arthritis, Sápmi, Scandinavia, Spondyloarthropathy, Statistical significance, T cell, Ulcerative colitis, Unfolded protein response, Uveitis, Yamato people.

Ankylosing spondylitis

Ankylosing spondylitis (AS) is a type of arthritis in which there is long term inflammation of the joints of the spine.

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In immunology, an antigen is a molecule capable of inducing an immune response (to produce an antibody) in the host organism.

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Beta-2 microglobulin

β2 microglobulin also known as B2M is a component of MHC class I molecules, MHC class I molecules have α1, α2, and α3 proteins which are present on all nucleated cells (excludes red blood cells).

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Caucasian race

The Caucasian race (also Caucasoid or Europid) is a grouping of human beings historically regarded as a biological taxon, which, depending on which of the historical race classifications used, have usually included some or all of the ancient and modern populations of Europe, the Caucasus, Asia Minor, North Africa, the Horn of Africa, Western Asia, Central Asia and South Asia.

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Chromosome 6

Chromosome 6 is one of the 23 pairs of chromosomes in humans.

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Cytotoxic T cell

A cytotoxic T cell (also known as TC, cytotoxic T lymphocyte, CTL, T-killer cell, cytolytic T cell, CD8+ T-cell or killer T cell) is a T lymphocyte (a type of white blood cell) that kills cancer cells, cells that are infected (particularly with viruses), or cells that are damaged in other ways.

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A disease is any condition which results in the disorder of a structure or function in an organism that is not due to any external injury.

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Endoplasmic reticulum

The endoplasmic reticulum (ER) is a type of organelle found in eukaryotic cells that forms an interconnected network of flattened, membrane-enclosed sacs or tube-like structures known as cisternae.

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European Bioinformatics Institute

The European Bioinformatics Institute (EMBL-EBI) is a centre for research and services in bioinformatics, and is part of European Molecular Biology Laboratory (EMBL).

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Han Chinese

The Han Chinese,.

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HLA-B (major histocompatibility complex, class I, B) is a human gene that provides instructions for making a protein that plays a critical role in the immune system.

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Human leukocyte antigen

The human leukocyte antigen (HLA) system or complex is a gene complex encoding the major histocompatibility complex (MHC) proteins in humans.

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Inflammatory bowel disease

Inflammatory bowel disease (IBD) is a group of inflammatory conditions of the colon and small intestine.

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Long-term nonprogressor

Long-term nonprogressors (LTNPs), sometimes also called "elite controllers", are individuals infected with HIV, who maintain a CD4 count greater than 500 without antiretroviral therapy with a detectable viral load.

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Major histocompatibility complex

The major histocompatibility complex (MHC) is a set of cell surface proteins essential for the acquired immune system to recognize foreign molecules in vertebrates, which in turn determines histocompatibility.

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Pathology (from the Ancient Greek roots of pathos (πάθος), meaning "experience" or "suffering" and -logia (-λογία), "study of") is a significant field in modern medical diagnosis and medical research, concerned mainly with the causal study of disease, whether caused by pathogens or non-infectious physiological disorder.

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Peptides (from Gr.: πεπτός, peptós "digested"; derived from πέσσειν, péssein "to digest") are short chains of amino acid monomers linked by peptide (amide) bonds.

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Psoriasis is a long-lasting autoimmune disease characterized by patches of abnormal skin.

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Psoriatic arthritis

Psoriatic arthritis is a long-term inflammatory arthritis that occurs in people affected by the autoimmune disease psoriasis.

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Reactive arthritis

Reactive arthritis, formerly known as Reiter's syndrome, is a form of inflammatory arthritis that develops in response to an infection in another part of the body (cross-reactivity).

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Sápmi, in English commonly known as Lapland, is the cultural region traditionally inhabited by the Sami people, traditionally known in English as Lapps.

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Scandinavia is a region in Northern Europe, with strong historical, cultural and linguistic ties.

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Spondyloarthropathy or spondyloarthrosis refers to any joint disease of the vertebral column.

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Statistical significance

In statistical hypothesis testing, a result has statistical significance when it is very unlikely to have occurred given the null hypothesis.

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T cell

A T cell, or T lymphocyte, is a type of lymphocyte (a subtype of white blood cell) that plays a central role in cell-mediated immunity.

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Ulcerative colitis

Ulcerative colitis (UC) is a long-term condition that results in inflammation and ulcers of the colon and rectum.

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Unfolded protein response

The unfolded protein response (UPR) is a cellular stress response related to the endoplasmic reticulum (ER) stress.

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Uveitis is the inflammation of the uvea, the pigmented layer that lies between the inner retina and the outer fibrous layer composed of the sclera and cornea.

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Yamato people

The and are an East Asian ethnic group and nation native to the Japanese archipelago.

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HLA B27, HLAB-27, HLAB27, Hla-b27 antigen, Hlab27.


[1] https://en.wikipedia.org/wiki/HLA-B27

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