57 relations: Acute myeloid leukemia, Acute panmyelosis with myelofibrosis, Anagrelide, Aspirin, Asymptomatic, Bone marrow, Budd–Chiari syndrome, Capillary leak syndrome, Chemotherapy, Complete blood count, Cyanosis, Deep vein thrombosis, Erlotinib, Erythrocyte sedimentation rate, Erythromelalgia, Erythropoietin, Essential thrombocythemia, Flushing (physiology), Gout, Granulocyte, Helicobacter pylori, Hematocrit, Hematopoietic stem cell transplantation, Hematopoietic ulcer, Hepatosplenomegaly, Histamine, Hydroxycarbamide, Interferon, Itch, Janus kinase, Janus kinase 2, Mayo Clinic, Megakaryocyte, Mount Sinai Hospital (Manhattan), Myelofibrosis, Myocardial infarction, Neoplasm, Olmsted County, Minnesota, Oncology, Peptic ulcer disease, Phlebotomy, Phosphorus-32, Platelet, Polycythemia, Prostaglandin, Pulmonary embolism, Red blood cell, Ruxolitinib, Stroke, Thrombocythemia, ..., Thrombosis, Tophus, Tyrosine kinase, URAC, Viscosity, White blood cell, Zeta potential. Expand index (7 more) »
Acute myeloid leukemia (AML) is a cancer of the myeloid line of blood cells, characterized by the rapid growth of abnormal cells that build up in the bone marrow and blood and interfere with normal blood cells.
Acute panmyelosis with myelofibrosis (APMF) it is a poorly defined disorder that arises as either a clonal disorder, or following toxic exposure to the bone marrow.
Anagrelide (Agrylin/Xagrid, Shire and Thromboreductin, AOP Orphan Pharmaceuticals AG) is a drug used for the treatment of essential thrombocytosis (ET; essential thrombocythemia), or overproduction of blood platelets. It also has been used in the treatment of chronic myeloid leukemia. Anagrelide controlled release (GALE-401) is in phase III clinical trials by Galena Biopharma for the treatment of ET.
Aspirin, also known as acetylsalicylic acid (ASA), is a medication used to treat pain, fever, or inflammation.
In medicine, a disease is considered asymptomatic if a patient is a carrier for a disease or infection but experiences no symptoms.
Bone marrow is a semi-solid tissue which may be found within the spongy or cancellous portions of bones.
Budd–Chiari syndrome is a very rare condition, affecting one in a million adults.
Capillary leak syndrome is characterized by the escape of blood plasma through capillary walls, from the blood circulatory system to surrounding tissues, muscle compartments, organs or body cavities.
Chemotherapy (often abbreviated to chemo and sometimes CTX or CTx) is a type of cancer treatment that uses one or more anti-cancer drugs (chemotherapeutic agents) as part of a standardized chemotherapy regimen.
A complete blood count (CBC), also known as a complete blood cell count, full blood count (FBC), or full blood exam (FBE), is a blood panel requested by a doctor or other medical professional that gives information about the cells in a patient's blood, such as the cell count for each cell type and the concentrations of various proteins and minerals.
Cyanosis is defined as the bluish or purplish discolouration of the skin or mucous membranes due to the tissues near the skin surface having low oxygen saturation.
Deep vein thrombosis (DVT), is the formation of a blood clot in a deep vein, most commonly the legs.
Erlotinib hydrochloride (trade name Tarceva) is a drug used to treat non-small cell lung cancer, pancreatic cancer and several other types of cancer.
The erythrocyte sedimentation rate (ESR or sed rate) is the rate at which red blood cells sediment in a period of one hour.
Erythromelalgia, formerly known as Mitchell's disease (after Silas Weir Mitchell), is a rare vascular peripheral pain disorder in which blood vessels, usually in the lower extremities or hands, are episodically blocked (frequently on and off daily), then become hyperemic and inflamed.
Erythropoietin (EPO), also known as hematopoietin or hemopoietin, is a glycoprotein cytokine secreted by the kidney in response to cellular hypoxia; it stimulates red blood cell production (erythropoiesis) in the bone marrow.
Essential thrombocythemia (ET) is a rare chronic blood condition characterised by the overproduction of platelets (thrombocytes) by megakaryocytes in the bone marrow.
For a person to flush is to become markedly red in the face and often other areas of the skin, from various physiological conditions.
Gout is a form of inflammatory arthritis characterized by recurrent attacks of a red, tender, hot, and swollen joint.
Granulocytes are a category of white blood cells characterized by the presence of granules in their cytoplasm.
Helicobacter pylori, previously known as Campylobacter pylori, is a gram-negative, microaerophilic bacterium usually found in the stomach.
The hematocrit (Ht or HCT), also known by several other names, is the volume percentage (vol%) of red blood cells in blood.
Hematopoietic stem cell transplantation (HSCT) is the transplantation of multipotent hematopoietic stem cells, usually derived from bone marrow, peripheral blood, or umbilical cord blood.
Hematopoietic ulcers are those occurring with sickle cell anemia, congenital hemolytic anemia, polycythemia vera, thrombocytopenic purpura, macroglobulinemia, and cryoglobulinemia.
Hepatosplenomegaly (commonly abbreviated HSM) is the simultaneous enlargement of both the liver (hepatomegaly) and the spleen (splenomegaly).
Histamine is an organic nitrogenous compound involved in local immune responses, as well as regulating physiological function in the gut and acting as a neurotransmitter for the brain, spinal cord, and uterus.
Hydroxycarbamide, also known as hydroxyurea, is a medication used in sickle-cell disease, chronic myelogenous leukemia, cervical cancer, and polycythemia vera.
Interferons (IFNs) are a group of signaling proteins made and released by host cells in response to the presence of several pathogens, such as viruses, bacteria, parasites, and also tumor cells.
Itch (also known as pruritus) is a sensation that causes the desire or reflex to scratch.
Janus kinase (JAK) is a family of intracellular, nonreceptor tyrosine kinases that transduce cytokine-mediated signals via the JAK-STAT pathway.
Janus kinase 2 (commonly called JAK2) is a non-receptor tyrosine kinase.
The Mayo Clinic is a nonprofit academic medical center based in Rochester, Minnesota focused on integrated clinical practice, education, and research.
A megakaryocyte (mega- + karyo- + -cyte, "large-nucleus cell") is a large bone marrow cell with a lobated nucleus responsible for the production of blood thrombocytes (platelets), which are necessary for normal blood clotting.
Mount Sinai Hospital, founded in 1852, is one of the oldest and largest teaching hospitals in the United States.
Myelofibrosis, also known as osteomyelofibrosis, is a relatively rare bone marrow cancer.
Myocardial infarction (MI), commonly known as a heart attack, occurs when blood flow decreases or stops to a part of the heart, causing damage to the heart muscle.
Neoplasia is a type of abnormal and excessive growth of tissue.
Olmsted County is a county in the U.S. state of Minnesota.
Oncology is a branch of medicine that deals with the prevention, diagnosis, and treatment of cancer.
Peptic ulcer disease (PUD) is a break in the lining of the stomach, first part of the small intestine or occasionally the lower esophagus.
Phlebotomy (from the Greek words phlebo-, meaning "pertaining to a blood vessel", and -tomia, meaning "cutting of") is the process of making an incision in a vein with a needle.
Phosphorus-32 is a radioactive isotope of phosphorus.
Platelets, also called thrombocytes (from Greek θρόμβος, "clot" and κύτος, "cell"), are a component of blood whose function (along with the coagulation factors) is to react to bleeding from blood vessel injury by clumping, thereby initiating a blood clot.
Polycythemia (also known as polycythaemia or polyglobulia) is a disease state in which the hematocrit (the volume percentage of red blood cells in the blood) is elevated.
The prostaglandins (PG) are a group of physiologically active lipid compounds having diverse hormone-like effects in animals.
Pulmonary embolism (PE) is a blockage of an artery in the lungs by a substance that has moved from elsewhere in the body through the bloodstream (embolism).
Red blood cells-- also known as RBCs, red cells, red blood corpuscles, haematids, erythroid cells or erythrocytes (from Greek erythros for "red" and kytos for "hollow vessel", with -cyte translated as "cell" in modern usage), are the most common type of blood cell and the vertebrate's principal means of delivering oxygen (O2) to the body tissues—via blood flow through the circulatory system.
Ruxolitinib (trade names Jakafi and Jakavi) is a drug for the treatment of intermediate or high-risk myelofibrosis, a type of myeloproliferative disorder that affects the bone marrow, and for polycythemia vera (PCV) when there has been an inadequate response to or intolerance of hydroxyurea.
A stroke is a medical condition in which poor blood flow to the brain results in cell death.
Thrombocythemia (also thrombocytosis) is the presence of high platelet (thrombocyte) counts in the blood, and can be either primary (also termed essential thrombocythemia, and caused by a myeloproliferative disease) or secondary (also termed reactive).
Thrombosis (from Ancient Greek θρόμβωσις thrómbōsis "clotting”) is the formation of a blood clot inside a blood vessel, obstructing the flow of blood through the circulatory system.
A tophus (Latin: "stone", plural tophi) is a deposit of uric acid crystals, in the form of monosodium urate crystals, in people with longstanding hyperuricemia (high levels of uric acid in the blood).
A tyrosine kinase is an enzyme that can transfer a phosphate group from ATP to a protein in a cell.
URAC is a Washington DC-based non-profit organization that helps promote health care quality through the accreditation of organizations involved in medical care services, as well as by offering education and measurement programs.
The viscosity of a fluid is the measure of its resistance to gradual deformation by shear stress or tensile stress.
White blood cells (WBCs), also called leukocytes or leucocytes, are the cells of the immune system that are involved in protecting the body against both infectious disease and foreign invaders.
Zeta potential is a scientific term for electrokinetic potential in colloidal dispersions.