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Medroxyprogesterone acetate

Index Medroxyprogesterone acetate

Medroxyprogesterone acetate (MPA), also known as depot medroxyprogesterone acetate (DMPA) in injectable form and sold under the brand name Depo-Provera among others, is a hormonal medication of the progestin type. [1]

Table of Contents

  1. 389 relations: Abdominal pain, Abnormal uterine bleeding, Acetate, Acetoxy group, Acne, Adrenal gland, Adrenal insufficiency, Adrenocorticotropic hormone, Adverse effect, Aggression, Agonist, Aldosterone, Allergy, Allopregnanolone, Allosteric modulator, Altered state of consciousness, Amenorrhea, American College of Obstetricians and Gynecologists, Aminoglutethimide, Anabolic steroid, Anabolism, Androgen, Androgen deprivation therapy, Androgen receptor, Androgen-dependent condition, Anesthesia, Angiogenesis inhibitor, Anterior pituitary, Anti-inflammatory, Antiandrogen, Anticonvulsant, Antiestrogen, Antigonadotropin, Anxiety, Anxiolytic, Appetite, Appetite stimulant, Area under the curve (pharmacokinetics), Artery, Atherosclerosis, Atrophic vaginitis, Atrophy, Aura (symptom), Autoimmune hemolytic anemia, Benign prostatic hyperplasia, Benzodiazepine, Bioavailability, Bioconjugation, Bioidentical hormone replacement therapy, Biological half-life, ... Expand index (339 more) »

  2. 3α-Hydroxysteroid dehydrogenase inhibitors
  3. 3β-Hydroxysteroid dehydrogenase inhibitors
  4. Appetite stimulants
  5. Feminizing hormone therapy

Abdominal pain

Abdominal pain, also known as a stomach ache, is a symptom associated with both non-serious and serious medical issues.

See Medroxyprogesterone acetate and Abdominal pain

Abnormal uterine bleeding

Abnormal uterine bleeding (AUB), also known as atypical vaginal bleeding (AVB), is vaginal bleeding from the uterus that is abnormally frequent, lasts excessively long, is heavier than normal, or is irregular.

See Medroxyprogesterone acetate and Abnormal uterine bleeding

Acetate

An acetate is a salt formed by the combination of acetic acid with a base (e.g. alkaline, earthy, metallic, nonmetallic or radical base).

See Medroxyprogesterone acetate and Acetate

Acetoxy group

In organic chemistry, the acetoxy group (abbr. AcO or OAc; IUPAC name: acetyloxy), is a functional group with the formula and the structure.

See Medroxyprogesterone acetate and Acetoxy group

Acne

Acne, also known as acne vulgaris, is a long-term skin condition that occurs when dead skin cells and oil from the skin clog hair follicles.

See Medroxyprogesterone acetate and Acne

Adrenal gland

The adrenal glands (also known as suprarenal glands) are endocrine glands that produce a variety of hormones including adrenaline and the steroids aldosterone and cortisol.

See Medroxyprogesterone acetate and Adrenal gland

Adrenal insufficiency

Adrenal insufficiency is a condition in which the adrenal glands do not produce adequate amounts of steroid hormones.

See Medroxyprogesterone acetate and Adrenal insufficiency

Adrenocorticotropic hormone

Adrenocorticotropic hormone (ACTH; also adrenocorticotropin, corticotropin) is a polypeptide tropic hormone produced by and secreted by the anterior pituitary gland.

See Medroxyprogesterone acetate and Adrenocorticotropic hormone

Adverse effect

An adverse effect is an undesired harmful effect resulting from a medication or other intervention, such as surgery.

See Medroxyprogesterone acetate and Adverse effect

Aggression

Aggression is a behavior aimed at opposing or attacking something or someone.

See Medroxyprogesterone acetate and Aggression

Agonist

An agonist is a chemical that activates a receptor to produce a biological response.

See Medroxyprogesterone acetate and Agonist

Aldosterone

Aldosterone is the main mineralocorticoid steroid hormone produced by the zona glomerulosa of the adrenal cortex in the adrenal gland. Medroxyprogesterone acetate and Aldosterone are pregnanes.

See Medroxyprogesterone acetate and Aldosterone

Allergy

Allergies, also known as allergic diseases, are various conditions caused by hypersensitivity of the immune system to typically harmless substances in the environment.

See Medroxyprogesterone acetate and Allergy

Allopregnanolone

Allopregnanolone is a naturally occurring neurosteroid which is made in the body from the hormone progesterone. Medroxyprogesterone acetate and Allopregnanolone are pregnanes and progestogens.

See Medroxyprogesterone acetate and Allopregnanolone

Allosteric modulator

In pharmacology and biochemistry, allosteric modulators are a group of substances that bind to a receptor to change that receptor's response to stimuli.

See Medroxyprogesterone acetate and Allosteric modulator

Altered state of consciousness

An altered state of consciousness (ASC), also called an altered state of mind, altered mental status (AMS) or mind alteration, is any condition which is significantly different from a normal waking state.

See Medroxyprogesterone acetate and Altered state of consciousness

Amenorrhea

Amenorrhea or amenorrhoea is the absence of a menstrual period in a female who has reached reproductive age.

See Medroxyprogesterone acetate and Amenorrhea

American College of Obstetricians and Gynecologists

The American College of Obstetricians and Gynecologists (ACOG) is a professional association of physicians specializing in obstetrics and gynecology in the United States.

See Medroxyprogesterone acetate and American College of Obstetricians and Gynecologists

Aminoglutethimide

Aminoglutethimide (AG), sold under the brand names Elipten, Cytadren, and Orimeten among others, is a medication which has been used in the treatment of seizures, Cushing's syndrome, breast cancer, and prostate cancer, among other indications. Medroxyprogesterone acetate and Aminoglutethimide are hormonal antineoplastic drugs.

See Medroxyprogesterone acetate and Aminoglutethimide

Anabolic steroid

Anabolic steroids, also known as anabolic-androgenic steroids (AAS), are a class of drugs that are structurally related to testosterone, the main male sex hormone, and produce effects by binding to the androgen receptor (AR). Medroxyprogesterone acetate and anabolic steroid are anabolic–androgenic steroids and hormonal antineoplastic drugs.

See Medroxyprogesterone acetate and Anabolic steroid

Anabolism

Anabolism is the set of metabolic pathways that construct macromolecules like DNA or RNA from smaller units.

See Medroxyprogesterone acetate and Anabolism

Androgen

An androgen (from Greek andr-, the stem of the word meaning "man") is any natural or synthetic steroid hormone that regulates the development and maintenance of male characteristics in vertebrates by binding to androgen receptors. Medroxyprogesterone acetate and androgen are anabolic–androgenic steroids.

See Medroxyprogesterone acetate and Androgen

Androgen deprivation therapy

Androgen deprivation therapy (ADT), also called androgen ablation therapy or androgen suppression therapy, is an antihormone therapy whose main use is in treating prostate cancer.

See Medroxyprogesterone acetate and Androgen deprivation therapy

Androgen receptor

The androgen receptor (AR), also known as NR3C4 (nuclear receptor subfamily 3, group C, member 4), is a type of nuclear receptor that is activated by binding any of the androgenic hormones, including testosterone and dihydrotestosterone, in the cytoplasm and then translocating into the nucleus.

See Medroxyprogesterone acetate and Androgen receptor

Androgen-dependent condition

An androgen-dependent condition, disease, disorder, or syndrome, is a medical condition that is, in part or full, dependent on, or is sensitive to, the presence of androgenic activity in the body.

See Medroxyprogesterone acetate and Androgen-dependent condition

Anesthesia

Anesthesia or anaesthesia is a state of controlled, temporary loss of sensation or awareness that is induced for medical or veterinary purposes.

See Medroxyprogesterone acetate and Anesthesia

Angiogenesis inhibitor

An angiogenesis inhibitor is a substance that inhibits the growth of new blood vessels (angiogenesis).

See Medroxyprogesterone acetate and Angiogenesis inhibitor

Anterior pituitary

A major organ of the endocrine system, the anterior pituitary (also called the adenohypophysis or pars anterior) is the glandular, anterior lobe that together with the posterior lobe (posterior pituitary, or the neurohypophysis) makes up the pituitary gland (hypophysis) which, in humans, is located at the base of the brain, protruding off the bottom of the hypothalamus.

See Medroxyprogesterone acetate and Anterior pituitary

Anti-inflammatory

Anti-inflammatory or antiphlogistic is the property of a substance or treatment that reduces inflammation or swelling.

See Medroxyprogesterone acetate and Anti-inflammatory

Antiandrogen

Antiandrogens, also known as androgen antagonists or testosterone blockers, are a class of drugs that prevent androgens like testosterone and dihydrotestosterone (DHT) from mediating their biological effects in the body. Medroxyprogesterone acetate and Antiandrogen are hormonal antineoplastic drugs.

See Medroxyprogesterone acetate and Antiandrogen

Anticonvulsant

Anticonvulsants (also known as antiepileptic drugs, antiseizure drugs, or anti-seizure medications (ASM)) are a diverse group of pharmacological agents used in the treatment of epileptic seizures.

See Medroxyprogesterone acetate and Anticonvulsant

Antiestrogen

Antiestrogens, also known as estrogen antagonists or estrogen blockers, are a class of drugs which prevent estrogens like estradiol from mediating their biological effects in the body. Medroxyprogesterone acetate and Antiestrogen are hormonal antineoplastic drugs.

See Medroxyprogesterone acetate and Antiestrogen

Antigonadotropin

An antigonadotropin is a drug which suppresses the activity and/or downstream effects of one or both of the gonadotropins, follicle-stimulating hormone (FSH) and luteinizing hormone (LH). Medroxyprogesterone acetate and antigonadotropin are antigonadotropins.

See Medroxyprogesterone acetate and Antigonadotropin

Anxiety

Anxiety is an emotion which is characterised by an unpleasant state of inner turmoil and includes feelings of dread over anticipated events.

See Medroxyprogesterone acetate and Anxiety

Anxiolytic

An anxiolytic (also antipanic or anti-anxiety agent) is a medication or other intervention that reduces anxiety.

See Medroxyprogesterone acetate and Anxiolytic

Appetite

Appetite is the desire to eat food items, usually due to hunger.

See Medroxyprogesterone acetate and Appetite

Appetite stimulant

An orexigenic, or appetite stimulant, is a drug, hormone, or compound that increases appetite and may induce hyperphagia. Medroxyprogesterone acetate and appetite stimulant are appetite stimulants.

See Medroxyprogesterone acetate and Appetite stimulant

Area under the curve (pharmacokinetics)

In the field of pharmacokinetics, the area under the curve (AUC) is the definite integral of the concentration of a drug in blood plasma as a function of time (this can be done using liquid chromatography–mass spectrometry).

See Medroxyprogesterone acetate and Area under the curve (pharmacokinetics)

Artery

An artery is a blood vessel in humans and most other animals that takes oxygenated blood away from the heart in the systemic circulation to one or more parts of the body.

See Medroxyprogesterone acetate and Artery

Atherosclerosis

Atherosclerosis is a pattern of the disease arteriosclerosis, characterized by development of abnormalities called lesions in walls of arteries.

See Medroxyprogesterone acetate and Atherosclerosis

Atrophic vaginitis

Atrophic vaginitis is inflammation of the vagina as a result of tissue thinning due to low estrogen levels.

See Medroxyprogesterone acetate and Atrophic vaginitis

Atrophy

Atrophy is the partial or complete wasting away of a part of the body.

See Medroxyprogesterone acetate and Atrophy

Aura (symptom)

An aura is a perceptual disturbance experienced by some with epilepsy or migraine.

See Medroxyprogesterone acetate and Aura (symptom)

Autoimmune hemolytic anemia

Autoimmune hemolytic anemia (AIHA) is an autoimmune disorder which occurs when antibodies directed against the person's own red blood cells (RBCs) cause them to burst (lyse), leading to an insufficient number of oxygen-carrying red blood cells in circulation (anemia).

See Medroxyprogesterone acetate and Autoimmune hemolytic anemia

Benign prostatic hyperplasia

Benign prostatic hyperplasia (BPH), also called prostate enlargement, is a noncancerous increase in size of the prostate gland.

See Medroxyprogesterone acetate and Benign prostatic hyperplasia

Benzodiazepine

Benzodiazepines (BZD, BDZ, BZs), colloquially called "benzos", are a class of depressant drugs whose core chemical structure is the fusion of a benzene ring and a diazepine ring.

See Medroxyprogesterone acetate and Benzodiazepine

Bioavailability

In pharmacology, bioavailability is a subcategory of absorption and is the fraction (%) of an administered drug that reaches the systemic circulation.

See Medroxyprogesterone acetate and Bioavailability

Bioconjugation

Bioconjugation is a chemical strategy to form a stable covalent link between two molecules, at least one of which is a biomolecule.

See Medroxyprogesterone acetate and Bioconjugation

Bioidentical hormone replacement therapy

Bioidentical hormone replacement therapy (BHRT), also known as bioidentical hormone therapy (BHT) or natural hormone therapy, is the use of hormones that are identical on a molecular level with endogenous hormones in hormone replacement therapy.

See Medroxyprogesterone acetate and Bioidentical hormone replacement therapy

Biological half-life

Biological half-life (elimination half-life, pharmacological half-life) is the time taken for concentration of a biological substance (such as a medication) to decrease from its maximum concentration (Cmax) to half of Cmax in the blood plasma.

See Medroxyprogesterone acetate and Biological half-life

Biological target

A biological target is anything within a living organism to which some other entity (like an endogenous ligand or a drug) is directed and/or binds, resulting in a change in its behavior or function.

See Medroxyprogesterone acetate and Biological target

Biosynthesis

Biosynthesis, i.e., chemical synthesis occuring in biological contexts, is a term most often referring to multi-step, enzyme-catalyzed processes where chemical substances absorbed as nutrients (or previously converted through biosynthesis) serve as enzyme substrates, with conversion by the living organism either into simpler or more complex products.

See Medroxyprogesterone acetate and Biosynthesis

Biotransformation

Biotransformation is the biochemical modification of one chemical compound or a mixture of chemical compounds.

See Medroxyprogesterone acetate and Biotransformation

Bipolar disorder

Bipolar disorder, previously known as manic depression, is a mental disorder characterized by periods of depression and periods of abnormally elevated mood that each last from days to weeks.

See Medroxyprogesterone acetate and Bipolar disorder

Birth control

Birth control, also known as contraception, anticonception, and fertility control, is the use of methods or devices to prevent unintended pregnancy.

See Medroxyprogesterone acetate and Birth control

Birth defect

A birth defect, also known as a congenital disorder, is an abnormal condition that is present at birth regardless of its cause.

See Medroxyprogesterone acetate and Birth defect

Blood vessel

Blood vessels are the structures of the circulatory system that transport blood throughout the human body.

See Medroxyprogesterone acetate and Blood vessel

Bone density

Bone density, or bone mineral density, is the amount of bone mineral in bone tissue.

See Medroxyprogesterone acetate and Bone density

Boxed warning

In the United States, a boxed warning (sometimes "black box warning", colloquially) is a type of warning that appears near the beginning of the package insert for certain prescription drugs, so called because the U.S. Food and Drug Administration specifies that it is formatted with a 'box' or border around the text to emphasize it is of utmost importance.

See Medroxyprogesterone acetate and Boxed warning

Breast cancer

Breast cancer is a cancer that develops from breast tissue.

See Medroxyprogesterone acetate and Breast cancer

Breast pain

Breast pain is the symptom of discomfort in either one or both breasts.

See Medroxyprogesterone acetate and Breast pain

Breastfeeding

Breastfeeding, variously known as chestfeeding or nursing, is the process where breast milk is fed to a child.

See Medroxyprogesterone acetate and Breastfeeding

Calcium channel

A calcium channel is an ion channel which shows selective permeability to calcium ions.

See Medroxyprogesterone acetate and Calcium channel

Cancer

Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body.

See Medroxyprogesterone acetate and Cancer

Carcinogen

A carcinogen is any agent that promotes the development of cancer.

See Medroxyprogesterone acetate and Carcinogen

Cardiovascular disease

Cardiovascular disease (CVD) is any disease involving the heart or blood vessels.

See Medroxyprogesterone acetate and Cardiovascular disease

Catamenial epilepsy

Catamenial epilepsy is a form of epilepsy in women where seizures are exacerbated during certain phases of the menstrual cycle.

See Medroxyprogesterone acetate and Catamenial epilepsy

Cell (biology)

The cell is the basic structural and functional unit of all forms of life.

See Medroxyprogesterone acetate and Cell (biology)

Cell proliferation

Cell proliferation is the process by which a cell grows and divides to produce two daughter cells.

See Medroxyprogesterone acetate and Cell proliferation

Cervix

The cervix (cervices) or cervix uteri is a dynamic fibromuscular organ of the female reproductive system that connects the vagina with the uterine cavity.

See Medroxyprogesterone acetate and Cervix

Chemical castration

Chemical castration is castration via anaphrodisiac drugs, whether to reduce libido and sexual activity, to treat cancer, or otherwise.

See Medroxyprogesterone acetate and Chemical castration

Chlormadinone acetate

Chlormadinone acetate (CMA), sold under the brand names Belara, Gynorelle, Lutéran, and Prostal among others, is a progestin and antiandrogen medication which is used in birth control pills to prevent pregnancy, as a component of menopausal hormone therapy, in the treatment of gynecological disorders, and in the treatment of androgen-dependent conditions like enlarged prostate and prostate cancer in men and acne and hirsutism in women. Medroxyprogesterone acetate and Chlormadinone acetate are acetate esters, antigonadotropins, Diketones, glucocorticoids, hormonal antineoplastic drugs, hormonal contraception, pregnanes, progestogen esters and progestogens.

See Medroxyprogesterone acetate and Chlormadinone acetate

Cholesterol side-chain cleavage enzyme

Cholesterol side-chain cleavage enzyme is commonly referred to as P450scc, where "scc" is an acronym for side-chain cleavage.

See Medroxyprogesterone acetate and Cholesterol side-chain cleavage enzyme

Cirrhosis

Cirrhosis, also known as liver cirrhosis or hepatic cirrhosis, and end-stage liver disease, is a condition of the liver in which the normal functioning tissue, or parenchyma, is replaced with scar tissue (fibrosis) and regenerative nodules as a result of chronic liver disease.

See Medroxyprogesterone acetate and Cirrhosis

Class action

A class action, also known as a class action lawsuit, class suit, or representative action, is a type of lawsuit where one of the parties is a group of people who are represented collectively by a member or members of that group.

See Medroxyprogesterone acetate and Class action

Clinical trial

Clinical trials are prospective biomedical or behavioral research studies on human participants designed to answer specific questions about biomedical or behavioral interventions, including new treatments (such as novel vaccines, drugs, dietary choices, dietary supplements, and medical devices) and known interventions that warrant further study and comparison.

See Medroxyprogesterone acetate and Clinical trial

Coagulation

Coagulation, also known as clotting, is the process by which blood changes from a liquid to a gel, forming a blood clot.

See Medroxyprogesterone acetate and Coagulation

Cognitive impairment

Cognitive impairment is an inclusive term to describe any characteristic that acts as a barrier to the cognition process or different areas of cognition.

See Medroxyprogesterone acetate and Cognitive impairment

Colorectal cancer

Colorectal cancer (CRC), also known as bowel cancer, colon cancer, or rectal cancer, is the development of cancer from the colon or rectum (parts of the large intestine).

See Medroxyprogesterone acetate and Colorectal cancer

Combined injectable birth control

Combined injectable contraceptives (CICs) are a form of hormonal birth control for women.

See Medroxyprogesterone acetate and Combined injectable birth control

Combined oral contraceptive pill

The combined oral contraceptive pill (COCP), often referred to as the birth control pill or colloquially as "the pill", is a type of birth control that is designed to be taken orally by women. Medroxyprogesterone acetate and combined oral contraceptive pill are world Health Organization essential medicines.

See Medroxyprogesterone acetate and Combined oral contraceptive pill

Competitive inhibition

Competitive inhibition is interruption of a chemical pathway owing to one chemical substance inhibiting the effect of another by competing with it for binding or bonding.

See Medroxyprogesterone acetate and Competitive inhibition

Conjugated estrogens

Conjugated estrogens (CEs), or conjugated equine estrogens (CEEs), sold under the brand name Premarin among others, is an estrogen medication which is used in menopausal hormone therapy and for various other indications. Medroxyprogesterone acetate and conjugated estrogens are antigonadotropins and hormonal antineoplastic drugs.

See Medroxyprogesterone acetate and Conjugated estrogens

Conjugated estrogens/medroxyprogesterone acetate

Conjugated estrogens/medroxyprogesterone acetate (CEs/MPA), sold under the brand names Prempro and Premphase, is a combination product of conjugated equine estrogens (Premarin), an estrogen collected from horse urine, and medroxyprogesterone acetate (Provera), a progestogen, which is used in menopausal hormone therapy for the treatment of menopausal symptoms.

See Medroxyprogesterone acetate and Conjugated estrogens/medroxyprogesterone acetate

Coronary artery disease

Coronary artery disease (CAD), also called coronary heart disease (CHD), ischemic heart disease (IHD), myocardial ischemia, or simply heart disease, involves the reduction of blood flow to the cardiac muscle due to build-up of atherosclerotic plaque in the arteries of the heart.

See Medroxyprogesterone acetate and Coronary artery disease

Corticosteroid

Corticosteroids are a class of steroid hormones that are produced in the adrenal cortex of vertebrates, as well as the synthetic analogues of these hormones.

See Medroxyprogesterone acetate and Corticosteroid

Cortisol

Cortisol is a steroid hormone in the glucocorticoid class of hormones and a stress hormone. Medroxyprogesterone acetate and Cortisol are glucocorticoids and pregnanes.

See Medroxyprogesterone acetate and Cortisol

Crohn's disease

Crohn's disease is a type of inflammatory bowel disease (IBD) that may affect any segment of the gastrointestinal tract.

See Medroxyprogesterone acetate and Crohn's disease

Cushing's syndrome

Cushing's syndrome is a collection of signs and symptoms due to prolonged exposure to glucocorticoids such as cortisol.

See Medroxyprogesterone acetate and Cushing's syndrome

CYP17A1

Cytochrome P450 17A1 (steroid 17α-monooxygenase, 17α-hydroxylase, 17-alpha-hydroxylase, 17,20-lyase, 17,20-desmolase) is an enzyme of the hydroxylase type that in humans is encoded by the CYP17A1 gene on chromosome 10.

See Medroxyprogesterone acetate and CYP17A1

CYP3A4

Cytochrome P450 3A4 (abbreviated CYP3A4) is an important enzyme in the body, mainly found in the liver and in the intestine, which in humans is encoded by CYP3A4 gene.

See Medroxyprogesterone acetate and CYP3A4

Cyproterone acetate

Cyproterone acetate (CPA), sold alone under the brand name Androcur or with ethinylestradiol under the brand names Diane or Diane-35 among others, is an antiandrogen and progestin medication used in the treatment of androgen-dependent conditions such as acne, excessive body hair growth, early puberty, and prostate cancer, as a component of feminizing hormone therapy for transgender individuals, and in birth control pills. Medroxyprogesterone acetate and Cyproterone acetate are 3β-Hydroxysteroid dehydrogenase inhibitors, acetate esters, antigonadotropins, glucocorticoids, hormonal antineoplastic drugs, pregnanes, progestogen esters and progestogens.

See Medroxyprogesterone acetate and Cyproterone acetate

Cytokine

Cytokines are a broad and loose category of small proteins (~5–25 kDa) important in cell signaling.

See Medroxyprogesterone acetate and Cytokine

Decidualization

Decidualization is a process that results in significant changes to cells of the endometrium in preparation for, and during, pregnancy.

See Medroxyprogesterone acetate and Decidualization

Deep vein thrombosis

Deep vein thrombosis (DVT) is a type of venous thrombosis involving the formation of a blood clot in a deep vein, most commonly in the legs or pelvis.

See Medroxyprogesterone acetate and Deep vein thrombosis

Dementia

Dementia is a syndrome associated with many neurodegenerative diseases, characterized by a general decline in cognitive abilities that affects a person's ability to perform everyday activities.

See Medroxyprogesterone acetate and Dementia

Deoxycorticosterone

Deoxycorticosterone (DOC), or desoxycorticosterone, may refer to. Medroxyprogesterone acetate and Deoxycorticosterone are pregnanes.

See Medroxyprogesterone acetate and Deoxycorticosterone

Depot injection

A depot injection is a term for an injection formulation of a medication which releases slowly over time to permit less frequent administration of a medication.

See Medroxyprogesterone acetate and Depot injection

Depression (mood)

Depression is a mental state of low mood and aversion to activity.

See Medroxyprogesterone acetate and Depression (mood)

Derivative (chemistry)

In chemistry, a derivative is a compound that is derived from a similar compound by a chemical reaction.

See Medroxyprogesterone acetate and Derivative (chemistry)

Developing country

A developing country is a sovereign state with a less developed industrial base and a lower Human Development Index (HDI) relative to other countries.

See Medroxyprogesterone acetate and Developing country

Dexamethasone

Dexamethasone is a fluorinated glucocorticoid medication used to treat rheumatic problems, a number of skin diseases, severe allergies, asthma, chronic obstructive lung disease, croup, brain swelling, eye pain following eye surgery, superior vena cava syndrome (a complication of some forms of cancer), and along with antibiotics in tuberculosis. Medroxyprogesterone acetate and Dexamethasone are glucocorticoids, pregnanes and world Health Organization essential medicines.

See Medroxyprogesterone acetate and Dexamethasone

Diabetes

Diabetes mellitus, often known simply as diabetes, is a group of common endocrine diseases characterized by sustained high blood sugar levels.

See Medroxyprogesterone acetate and Diabetes

Diabetic nephropathy

Diabetic nephropathy, also known as diabetic kidney disease, is the chronic loss of kidney function occurring in those with diabetes mellitus.

See Medroxyprogesterone acetate and Diabetic nephropathy

Diabetic neuropathy

Diabetic neuropathy is various types of nerve damage associated with diabetes mellitus.

See Medroxyprogesterone acetate and Diabetic neuropathy

Diabetic retinopathy

Diabetic retinopathy (also known as diabetic eye disease), is a medical condition in which damage occurs to the retina due to diabetes.

See Medroxyprogesterone acetate and Diabetic retinopathy

Diana Miglioretti

Diana Lynn Miglioretti is an American biostatistician specializing in the availability and effectiveness of breast cancer screening and in radiation hazards from medical imaging; she has also studied connections between Down syndrome and leukemia.

See Medroxyprogesterone acetate and Diana Miglioretti

Diethylstilbestrol

Diethylstilbestrol (DES), also known as stilbestrol or stilboestrol, is a nonsteroidal estrogen medication, which is presently rarely used. Medroxyprogesterone acetate and Diethylstilbestrol are antigonadotropins and hormonal antineoplastic drugs.

See Medroxyprogesterone acetate and Diethylstilbestrol

Dihydrotestosterone

Dihydrotestosterone (DHT, 5α-dihydrotestosterone, 5α-DHT, androstanolone or stanolone) is an endogenous androgen sex steroid and hormone primarily involved in the growth and repair of the prostate and the penis, as well as the production of sebum and body hair composition. Medroxyprogesterone acetate and Dihydrotestosterone are anabolic–androgenic steroids.

See Medroxyprogesterone acetate and Dihydrotestosterone

Dissociation constant

In chemistry, biochemistry, and pharmacology, a dissociation constant (KD) is a specific type of equilibrium constant that measures the propensity of a larger object to separate (dissociate) reversibly into smaller components, as when a complex falls apart into its component molecules, or when a salt splits up into its component ions.

See Medroxyprogesterone acetate and Dissociation constant

Dizziness

Dizziness is an imprecise term that can refer to a sense of disorientation in space, vertigo, or lightheadedness.

See Medroxyprogesterone acetate and Dizziness

Downregulation and upregulation

In biochemistry, in the biological context of organisms' regulation of gene expression and production of gene products, downregulation is the process by which a cell decreases the production and quantities of its cellular components, such as RNA and proteins, in response to an external stimulus.

See Medroxyprogesterone acetate and Downregulation and upregulation

Drug interaction

In pharmaceutical sciences, drug interactions occur when a drug's mechanism of action is affected by the concomitant administration of substances such as foods, beverages, or other drugs.

See Medroxyprogesterone acetate and Drug interaction

Dydrogesterone

Dydrogesterone, sold under the brand name Duphaston among others, is a progestin medication which is used for a variety of indications, including threatened or recurrent miscarriage during pregnancy, dysfunctional bleeding, infertility due to luteal insufficiency, dysmenorrhea, endometriosis, secondary amenorrhea, irregular cycles, premenstrual syndrome, and as a component of menopausal hormone therapy. Medroxyprogesterone acetate and Dydrogesterone are Diketones, pregnanes and progestogens.

See Medroxyprogesterone acetate and Dydrogesterone

Dysmenorrhea

Dysmenorrhea, also known as period pain, painful periods or menstrual cramps, is pain during menstruation.

See Medroxyprogesterone acetate and Dysmenorrhea

Dysuria

Dysuria refers to painful or uncomfortable urination.

See Medroxyprogesterone acetate and Dysuria

EC50

Half maximal effective concentration (EC50) is a measure of the concentration of a drug, antibody or toxicant which induces a biological response halfway between the baseline and maximum after a specified exposure time.

See Medroxyprogesterone acetate and EC50

Ectopic pregnancy

Ectopic pregnancy is a complication of pregnancy in which the embryo attaches outside the uterus.

See Medroxyprogesterone acetate and Ectopic pregnancy

Edema

Edema (AmE), also spelled oedema (BrE), and also known as fluid retention, dropsy, hydropsy and swelling, is the build-up of fluid in the body's tissue.

See Medroxyprogesterone acetate and Edema

Ejaculation

Ejaculation is the discharge of semen (the ejaculate; normally containing sperm) through the urethra in men.

See Medroxyprogesterone acetate and Ejaculation

Elimination (pharmacology)

In pharmacology, the elimination or excretion of a drug is understood to be any one of a number of processes by which a drug is eliminated (that is, cleared and excreted) from an organism either in an unaltered form (unbound molecules) or modified as a metabolite.

See Medroxyprogesterone acetate and Elimination (pharmacology)

Elsevier

Elsevier is a Dutch academic publishing company specializing in scientific, technical, and medical content.

See Medroxyprogesterone acetate and Elsevier

Endometrial cancer

Endometrial cancer is a cancer that arises from the endometrium (the lining of the uterus or womb).

See Medroxyprogesterone acetate and Endometrial cancer

Endometrial hyperplasia

Endometrial hyperplasia is a condition of excessive proliferation of the cells of the endometrium, or inner lining of the uterus.

See Medroxyprogesterone acetate and Endometrial hyperplasia

Endometriosis

Endometriosis is a disease in which cells like those in the endometrium, the layer of tissue that normally covers the inside of the uterus, grow outside the uterus.

See Medroxyprogesterone acetate and Endometriosis

Endometrium

The endometrium is the inner epithelial layer, along with its mucous membrane, of the mammalian uterus.

See Medroxyprogesterone acetate and Endometrium

Enzyme

Enzymes are proteins that act as biological catalysts by accelerating chemical reactions.

See Medroxyprogesterone acetate and Enzyme

Enzyme induction and inhibition

Enzyme induction is a process in which a molecule (e.g. a drug) induces (i.e. initiates or enhances) the expression of an enzyme.

See Medroxyprogesterone acetate and Enzyme induction and inhibition

Enzyme inhibitor

An enzyme inhibitor is a molecule that binds to an enzyme and blocks its activity.

See Medroxyprogesterone acetate and Enzyme inhibitor

Epilepsy

Epilepsy is a group of non-communicable neurological disorders characterized by recurrent epileptic seizures.

See Medroxyprogesterone acetate and Epilepsy

Epithelium

Epithelium or epithelial tissue is a thin, continuous, protective layer of compactly packed cells with little extracellular matrix.

See Medroxyprogesterone acetate and Epithelium

Erectile dysfunction

Erectile dysfunction (ED), also referred to as impotence, is a form of sexual dysfunction in males characterized by the persistent or recurring inability to achieve or maintain a penile erection with sufficient rigidity and duration for satisfactory sexual activity.

See Medroxyprogesterone acetate and Erectile dysfunction

Ester

In chemistry, an ester is a functional group derived from an acid (organic or inorganic) in which the hydrogen atom (H) of at least one acidic hydroxyl group of that acid is replaced by an organyl group.

See Medroxyprogesterone acetate and Ester

Estradiol

Estradiol (E2), also spelled oestradiol, is an estrogen steroid hormone and the major female sex hormone. Medroxyprogesterone acetate and Estradiol are antigonadotropins and feminizing hormone therapy.

See Medroxyprogesterone acetate and Estradiol

Estradiol (medication)

Estradiol (E2) is a medication and naturally occurring steroid hormone. Medroxyprogesterone acetate and Estradiol (medication) are antigonadotropins and hormonal antineoplastic drugs.

See Medroxyprogesterone acetate and Estradiol (medication)

Estradiol cypionate

Estradiol cypionate (EC), sold under the brand name Depo-Estradiol among others, is an estrogen medication which is used in hormone therapy for menopausal symptoms and low estrogen levels in women, in hormone therapy for trans women, and in hormonal birth control for women. Medroxyprogesterone acetate and Estradiol cypionate are antigonadotropins and hormonal contraception.

See Medroxyprogesterone acetate and Estradiol cypionate

Estradiol cypionate/medroxyprogesterone acetate

Estradiol cypionate/medroxyprogesterone acetate (EC/MPA), sold under the brand name Cyclofem among others, is a form of combined injectable birth control. Medroxyprogesterone acetate and Estradiol cypionate/medroxyprogesterone acetate are world Health Organization essential medicines.

See Medroxyprogesterone acetate and Estradiol cypionate/medroxyprogesterone acetate

Estradiol valerate

Estradiol valerate (EV), sold for use by mouth under the brand name Progynova and for use by injection under the brand names Delestrogen and Progynon Depot among others, is an estrogen medication. Medroxyprogesterone acetate and Estradiol valerate are antigonadotropins, hormonal antineoplastic drugs and hormonal contraception.

See Medroxyprogesterone acetate and Estradiol valerate

Estradiol/medroxyprogesterone acetate

Estradiol/medroxyprogesterone acetate (E2/MPA), sold under the brand names Indivina and Tridestra among others, is a combination product of estradiol, an estrogen, and medroxyprogesterone acetate, a progestogen, which is used in menopausal hormone therapy for the treatment of menopausal symptoms.

See Medroxyprogesterone acetate and Estradiol/medroxyprogesterone acetate

Estrogen

Estrogen (oestrogen; see spelling differences) is a category of sex hormone responsible for the development and regulation of the female reproductive system and secondary sex characteristics. Medroxyprogesterone acetate and Estrogen are antigonadotropins.

See Medroxyprogesterone acetate and Estrogen

Estrogen (medication)

An estrogen (E) is a type of medication which is used most commonly in hormonal birth control and menopausal hormone therapy, and as part of feminizing hormone therapy for transgender women. Medroxyprogesterone acetate and estrogen (medication) are antigonadotropins and hormonal antineoplastic drugs.

See Medroxyprogesterone acetate and Estrogen (medication)

Estrogen receptor

Estrogen receptors (ERs) are a group of proteins found inside cells.

See Medroxyprogesterone acetate and Estrogen receptor

Estrogen-dependent condition

An estrogen-dependent condition can be that relating to the differentiation in the steroid sex hormone that is associated with the female reproductive system and sex characteristics.

See Medroxyprogesterone acetate and Estrogen-dependent condition

Ethinylestradiol

Ethinylestradiol (EE) is an estrogen medication which is used widely in birth control pills in combination with progestins. Medroxyprogesterone acetate and Ethinylestradiol are antigonadotropins, hormonal antineoplastic drugs and hormonal contraception.

See Medroxyprogesterone acetate and Ethinylestradiol

Excretion

Excretion is elimination of metabolic waste, which is an essential process in all organisms.

See Medroxyprogesterone acetate and Excretion

Familial male-limited precocious puberty

Familial male-limited precocious puberty, often abbreviated as FMPP, also known as familial sexual precocity or gonadotropin-independent testotoxicosis, is a form of gonadotropin-independent precocious puberty in which boys experience early onset and progression of puberty.

See Medroxyprogesterone acetate and Familial male-limited precocious puberty

Fatigue

Fatigue describes a state of tiredness (which is not sleepiness), exhaustion or loss of energy.

See Medroxyprogesterone acetate and Fatigue

Feces

Feces (or faeces;: faex) are the solid or semi-solid remains of food that was not digested in the small intestine, and has been broken down by bacteria in the large intestine.

See Medroxyprogesterone acetate and Feces

Feminizing hormone therapy

Feminizing hormone therapy, also known as transfeminine hormone therapy, is hormone therapy and sex reassignment therapy to change the secondary sex characteristics of transgender people from masculine or androgynous to feminine.

See Medroxyprogesterone acetate and Feminizing hormone therapy

Fertilisation

Fertilisation or fertilization (see spelling differences), also known as generative fertilisation, syngamy and impregnation, is the fusion of gametes to give rise to a zygote and initiate its development into a new individual organism or offspring.

See Medroxyprogesterone acetate and Fertilisation

Fertility

Fertility in colloquial terms refers the ability to have offspring.

See Medroxyprogesterone acetate and Fertility

Fetus

A fetus or foetus (fetuses, foetuses, rarely feti or foeti) is the unborn offspring that develops from a mammal embryo.

See Medroxyprogesterone acetate and Fetus

Fibrinolysis

Fibrinolysis is a process that prevents blood clots from growing and becoming problematic.

See Medroxyprogesterone acetate and Fibrinolysis

Flunitrazepam

Flunitrazepam, sold under the brand name Rohypnol among others, is a benzodiazepine used to treat severe insomnia and assist with anesthesia.

See Medroxyprogesterone acetate and Flunitrazepam

Fluorine

Fluorine is a chemical element; it has symbol F and atomic number 9.

See Medroxyprogesterone acetate and Fluorine

Fluoromedroxyprogesterone acetate

Fluoromedroxyprogesterone acetate (FMPA, 9α-fluoromedroxyprogesterone acetate, or 9α-FMPA) is a synthetic steroid medication which was under development by Meiji Dairies Corporation in the 1990s and 2000s for the potential treatment of cancers but was never marketed. Medroxyprogesterone acetate and Fluoromedroxyprogesterone acetate are acetate esters, drugs with unknown mechanisms of action, glucocorticoids, pregnanes, progestogen esters and progestogens.

See Medroxyprogesterone acetate and Fluoromedroxyprogesterone acetate

Follicle-stimulating hormone

Follicle-stimulating hormone (FSH) is a gonadotropin, a glycoprotein polypeptide hormone.

See Medroxyprogesterone acetate and Follicle-stimulating hormone

Follicular phase

The follicular phase, also known as the preovulatory phase or proliferative phase, is the phase of the estrous cycle (or, in primates for example, the menstrual cycle) during which follicles in the ovary mature from primary follicle to a fully mature graafian follicle.

See Medroxyprogesterone acetate and Follicular phase

Food and Drug Administration

The United States Food and Drug Administration (FDA or US FDA) is a federal agency of the Department of Health and Human Services.

See Medroxyprogesterone acetate and Food and Drug Administration

France

France, officially the French Republic, is a country located primarily in Western Europe.

See Medroxyprogesterone acetate and France

Functional group

In organic chemistry, a functional group is a substituent or moiety in a molecule that causes the molecule's characteristic chemical reactions.

See Medroxyprogesterone acetate and Functional group

GABAA receptor

The GABAA receptor (GABAAR) is an ionotropic receptor and ligand-gated ion channel.

See Medroxyprogesterone acetate and GABAA receptor

Germany

Germany, officially the Federal Republic of Germany (FRG), is a country in Central Europe.

See Medroxyprogesterone acetate and Germany

Glucocorticoid

Glucocorticoids (or, less commonly, glucocorticosteroids) are a class of corticosteroids, which are a class of steroid hormones. Medroxyprogesterone acetate and Glucocorticoid are glucocorticoids.

See Medroxyprogesterone acetate and Glucocorticoid

Glucocorticoid receptor

The glucocorticoid receptor (GR or GCR) also known as NR3C1 (nuclear receptor subfamily 3, group C, member 1) is the receptor to which cortisol and other glucocorticoids bind.

See Medroxyprogesterone acetate and Glucocorticoid receptor

Gonadotropin

Gonadotropins are glycoprotein hormones secreted by gonadotropic cells of the anterior pituitary of vertebrates.

See Medroxyprogesterone acetate and Gonadotropin

Gonadotropin-releasing hormone

Gonadotropin-releasing hormone (GnRH) is a releasing hormone responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary. Medroxyprogesterone acetate and Gonadotropin-releasing hormone are antigonadotropins.

See Medroxyprogesterone acetate and Gonadotropin-releasing hormone

Gynaecology

Gynaecology or gynecology (see American and British English spelling differences) is the area of medicine that involves the treatment of women's diseases, especially those of the reproductive organs.

See Medroxyprogesterone acetate and Gynaecology

Headache

Headache, also known as cephalalgia, is the symptom of pain in the face, head, or neck.

See Medroxyprogesterone acetate and Headache

Hepatitis

Hepatitis is inflammation of the liver tissue.

See Medroxyprogesterone acetate and Hepatitis

Hepatocellular adenoma

Hepatocellular adenoma (also known as hepatic adenoma or hepadenoma) is a rare, benign liver tumor.

See Medroxyprogesterone acetate and Hepatocellular adenoma

Hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer in adults and is currently the most common cause of death in people with cirrhosis.

See Medroxyprogesterone acetate and Hepatocellular carcinoma

High-density lipoprotein

High-density lipoprotein (HDL) is one of the five major groups of lipoproteins.

See Medroxyprogesterone acetate and High-density lipoprotein

High-dose estrogen therapy

High-dose estrogen therapy (HDE) is a type of hormone therapy in which high doses of estrogens are given. Medroxyprogesterone acetate and high-dose estrogen therapy are antigonadotropins and hormonal antineoplastic drugs.

See Medroxyprogesterone acetate and High-dose estrogen therapy

Hip fracture

A hip fracture is a break that occurs in the upper part of the femur (thigh bone), at the femoral neck or (rarely) the femoral head.

See Medroxyprogesterone acetate and Hip fracture

Hirsutism

Hirsutism is excessive body hair on parts of the body where hair is normally absent or minimal.

See Medroxyprogesterone acetate and Hirsutism

Homogeneity and heterogeneity

Homogeneity and heterogeneity are concepts relating to the uniformity of a substance, process or image.

See Medroxyprogesterone acetate and Homogeneity and heterogeneity

Hormonal contraception

Hormonal contraception refers to birth control methods that act on the endocrine system.

See Medroxyprogesterone acetate and Hormonal contraception

Hormone

A hormone (from the Greek participle ὁρμῶν, "setting in motion") is a class of signaling molecules in multicellular organisms that are sent to distant organs or tissues by complex biological processes to regulate physiology and behavior.

See Medroxyprogesterone acetate and Hormone

Hormone replacement therapy

Hormone replacement therapy (HRT), also known as menopausal hormone therapy or postmenopausal hormone therapy, is a form of hormone therapy used to treat symptoms associated with female menopause.

See Medroxyprogesterone acetate and Hormone replacement therapy

Hormone-sensitive cancer

A hormone-sensitive cancer, or hormone-dependent cancer, is a type of cancer that is dependent on a hormone for growth and/or survival.

See Medroxyprogesterone acetate and Hormone-sensitive cancer

Hot flash

Hot flashes (also known as hot flushes) are a form of flushing, often caused by the changing hormone levels that are characteristic of menopause.

See Medroxyprogesterone acetate and Hot flash

HSD3B2

HSD3B2 is a human gene that encodes for 3beta-hydroxysteroid dehydrogenase/delta(5)-delta(4)isomerase type II or hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2.

See Medroxyprogesterone acetate and HSD3B2

Human fertilization

Human fertilization is the union of an egg and sperm, occurring primarily in the ampulla of the fallopian tube.

See Medroxyprogesterone acetate and Human fertilization

Human serum albumin

Human serum albumin is the serum albumin found in human blood.

See Medroxyprogesterone acetate and Human serum albumin

Hydroxylation

In chemistry, hydroxylation can refer to.

See Medroxyprogesterone acetate and Hydroxylation

Hydroxyprogesterone acetate

Hydroxyprogesterone acetate (OHPA), sold under the brand name Prodox, is an orally active progestin related to hydroxyprogesterone caproate (OHPC) which has been used in clinical and veterinary medicine. Medroxyprogesterone acetate and hydroxyprogesterone acetate are acetate esters, pregnanes, progestogen esters and progestogens.

See Medroxyprogesterone acetate and Hydroxyprogesterone acetate

Hypericum perforatum

Hypericum perforatum, commonly known as St John's wort (sometimes perforate St John's wort or common St John's wort), is a flowering plant in the family Hypericaceae.

See Medroxyprogesterone acetate and Hypericum perforatum

Hypersexuality

Hypersexuality is a presumed mental disorder that causes unwanted or excessive sexual arousal, causing people to engage in or think about sexual activity to a point of distress or impairment.

See Medroxyprogesterone acetate and Hypersexuality

Hypertension

Hypertension, also known as high blood pressure, is a long-term medical condition in which the blood pressure in the arteries is persistently elevated.

See Medroxyprogesterone acetate and Hypertension

Hypnotic

Hypnotic (from Greek Hypnos, sleep), or soporific drugs, commonly known as sleeping pills, are a class of (and umbrella term for) psychoactive drugs whose primary function is to induce sleep (or surgical anesthesiaWhen used in anesthesia to produce and maintain unconsciousness, "sleep" is metaphorical as there are no regular sleep stages or cyclical natural states; patients rarely recover from anesthesia feeling refreshed and with renewed energy.

See Medroxyprogesterone acetate and Hypnotic

Hypoestrogenism

Hypoestrogenism, or estrogen deficiency, refers to a lower than normal level of estrogen.

See Medroxyprogesterone acetate and Hypoestrogenism

Hypothalamic–pituitary hormone

Hypothalamic–pituitary hormones are hormones that are produced by the hypothalamus and pituitary gland.

See Medroxyprogesterone acetate and Hypothalamic–pituitary hormone

Hypothalamic–pituitary–adrenal axis

The hypothalamic–pituitary–adrenal axis (HPA axis or HTPA axis) is a complex set of direct influences and feedback interactions among three components: the hypothalamus (a part of the brain located below the thalamus), the pituitary gland (a pea-shaped structure located below the hypothalamus), and the adrenal (also called "suprarenal") glands (small, conical organs on top of the kidneys).

See Medroxyprogesterone acetate and Hypothalamic–pituitary–adrenal axis

Hypothalamic–pituitary–gonadal axis

The hypothalamic–pituitary–gonadal axis (HPG axis, also known as the hypothalamic–pituitary–ovarian/testicular axis) refers to the hypothalamus, pituitary gland, and gonadal glands as if these individual endocrine glands were a single entity.

See Medroxyprogesterone acetate and Hypothalamic–pituitary–gonadal axis

Hypothalamus

The hypothalamus (hypothalami) is a small part of the vertebrate brain that contains a number of nuclei with a variety of functions.

See Medroxyprogesterone acetate and Hypothalamus

IC50

Half maximal inhibitory concentration (IC50) is a measure of the potency of a substance in inhibiting a specific biological or biochemical function.

See Medroxyprogesterone acetate and IC50

Immune thrombocytopenic purpura

Immune thrombocytopenic purpura (ITP), also known as idiopathic thrombocytopenic purpura or immune thrombocytopenia, is an autoimmune primary disorder of hemostasis characterized by a low platelet count in the absence of other causes.

See Medroxyprogesterone acetate and Immune thrombocytopenic purpura

In vitro

In vitro (meaning in glass, or in the glass) studies are performed with microorganisms, cells, or biological molecules outside their normal biological context.

See Medroxyprogesterone acetate and In vitro

Indian Journal of Medical Ethics

The Indian Journal of Medical Ethics is a quarterly peer-reviewed academic journal covering medical ethics and bioethics.

See Medroxyprogesterone acetate and Indian Journal of Medical Ethics

Indonesia

Indonesia, officially the Republic of Indonesia, is a country in Southeast Asia and Oceania between the Indian and Pacific oceans.

See Medroxyprogesterone acetate and Indonesia

Inflammatory cytokine

An inflammatory cytokine or proinflammatory cytokine is a type of signaling molecule (a cytokine) that is secreted from immune cells like helper T cells (Th) and macrophages, and certain other cell types that promote inflammation.

See Medroxyprogesterone acetate and Inflammatory cytokine

Injection (medicine)

An injection (often and usually referred to as a "shot" in US English, a "jab" in UK English, or a "jag" in Scottish English and Scots) is the act of administering a liquid, especially a drug, into a person's body using a needle (usually a hypodermic needle) and a syringe.

See Medroxyprogesterone acetate and Injection (medicine)

Interleukin 1 beta

Interleukin-1 beta (IL-1β) also known as leukocytic pyrogen, leukocytic endogenous mediator, mononuclear cell factor, lymphocyte activating factor and other names, is a cytokine protein that in humans is encoded by the IL1B gene.

See Medroxyprogesterone acetate and Interleukin 1 beta

Interleukin 1-alpha

Interleukin-1 alpha (IL-1 alpha) also known as hematopoietin 1 is a cytokine of the interleukin 1 family that in humans is encoded by the IL1A gene.

See Medroxyprogesterone acetate and Interleukin 1-alpha

Interleukin 6

Interleukin 6 (IL-6) is an interleukin that acts as both a pro-inflammatory cytokine and an anti-inflammatory myokine.

See Medroxyprogesterone acetate and Interleukin 6

Intermenstrual bleeding

Intermenstrual bleeding (IMB) is vaginal bleeding at irregular intervals between expected menstrual periods.

See Medroxyprogesterone acetate and Intermenstrual bleeding

Intramuscular injection

Intramuscular injection, often abbreviated IM, is the injection of a substance into a muscle.

See Medroxyprogesterone acetate and Intramuscular injection

Intrauterine device

An intrauterine device (IUD), also known as intrauterine contraceptive device (IUCD or ICD) or coil, is a small, often T-shaped birth control device that is inserted into the uterus to prevent pregnancy.

See Medroxyprogesterone acetate and Intrauterine device

Intravenous therapy

Intravenous therapy (abbreviated as IV therapy) is a medical technique that administers fluids, medications and nutrients directly into a person's vein.

See Medroxyprogesterone acetate and Intravenous therapy

Intrinsic activity

Intrinsic activity (IA) and efficacy refer to the relative ability of a drug-receptor complex to produce a maximum functional response.

See Medroxyprogesterone acetate and Intrinsic activity

Iron deficiency

Iron deficiency, or sideropenia, is the state in which a body lacks enough iron to supply its needs.

See Medroxyprogesterone acetate and Iron deficiency

Iron-deficiency anemia

Iron-deficiency anemia is anemia caused by a lack of iron.

See Medroxyprogesterone acetate and Iron-deficiency anemia

Irregular menstruation

Irregular menstruation is a menstrual disorder whose manifestations include irregular cycle lengths as well as metrorrhagia (vaginal bleeding between expected periods).

See Medroxyprogesterone acetate and Irregular menstruation

Israel

Israel, officially the State of Israel, is a country in the Southern Levant, West Asia.

See Medroxyprogesterone acetate and Israel

Kidney cancer

Kidney cancer, also known as renal cancer, is a group of cancers that starts in the kidney.

See Medroxyprogesterone acetate and Kidney cancer

Levonorgestrel-releasing implant

Levonorgestrel-releasing implant, sold under the brand name Jadelle among others, are devices that release levonorgestrel for birth control. Medroxyprogesterone acetate and levonorgestrel-releasing implant are hormonal contraception and world Health Organization essential medicines.

See Medroxyprogesterone acetate and Levonorgestrel-releasing implant

Libido

In psychology, libido (from the Latin, 'desire') is psychic drive or energy, usually conceived as sexual in nature, but sometimes conceived as including other forms of desire.

See Medroxyprogesterone acetate and Libido

Ligand (biochemistry)

In biochemistry and pharmacology, a ligand is a substance that forms a complex with a biomolecule to serve a biological purpose.

See Medroxyprogesterone acetate and Ligand (biochemistry)

Liquid chromatography–mass spectrometry

Liquid chromatography–mass spectrometry (LC–MS) is an analytical chemistry technique that combines the physical separation capabilities of liquid chromatography (or HPLC) with the mass analysis capabilities of mass spectrometry (MS).

See Medroxyprogesterone acetate and Liquid chromatography–mass spectrometry

Liver

The liver is a major metabolic organ exclusively found in vertebrate animals, which performs many essential biological functions such as detoxification of the organism, and the synthesis of proteins and various other biochemicals necessary for digestion and growth.

See Medroxyprogesterone acetate and Liver

Liver cancer

Liver cancer, also known as hepatic cancer, primary hepatic cancer, or primary hepatic malignancy, is cancer that starts in the liver.

See Medroxyprogesterone acetate and Liver cancer

Liver disease

Liver disease, or hepatic disease, is any of many diseases of the liver.

See Medroxyprogesterone acetate and Liver disease

Long-acting reversible contraceptives

Long-acting reversible contraceptives (LARC) are methods of birth control that provide effective contraception for an extended period without requiring user action.

See Medroxyprogesterone acetate and Long-acting reversible contraceptives

Lost to follow-up

In the clinical research trial industry, loss to follow-up refers to patients who at one point in time were actively participating in a clinical research trial, but have become lost (either by error in a computer tracking system or by being unreachable) at the point of follow-up in the trial.

See Medroxyprogesterone acetate and Lost to follow-up

Louisiana

Louisiana (Louisiane; Luisiana; Lwizyàn) is a state in the Deep South and South Central regions of the United States.

See Medroxyprogesterone acetate and Louisiana

Luteal phase

The menstrual cycle is on average 28 days in length.

See Medroxyprogesterone acetate and Luteal phase

Luteinizing hormone

Luteinizing hormone (LH, also known as luteinising hormone, lutropin and sometimes lutrophin) is a hormone produced by gonadotropic cells in the anterior pituitary gland.

See Medroxyprogesterone acetate and Luteinizing hormone

Male contraceptive

Male contraceptives, also known as male birth control, are methods of preventing pregnancy by interrupting the function of sperm.

See Medroxyprogesterone acetate and Male contraceptive

Mania

Mania, also known as manic syndrome, is a mental and behavioral disorder defined as a state of abnormally elevated arousal, affect, and energy level, or "a state of heightened overall activation with enhanced affective expression together with lability of affect." During a manic episode, an individual will experience rapidly changing emotions and moods, highly influenced by surrounding stimuli.

See Medroxyprogesterone acetate and Mania

MCF-7

MCF-7 is a breast cancer cell line isolated in 1970 from a 69-year-old White woman.

See Medroxyprogesterone acetate and MCF-7

Mechanism of action

In pharmacology, the term mechanism of action (MOA) refers to the specific biochemical interaction through which a drug substance produces its pharmacological effect.

See Medroxyprogesterone acetate and Mechanism of action

Medical experimentation in Africa

African countries have been sites for clinical trials by large pharmaceutical companies, raising human rights concerns.

See Medroxyprogesterone acetate and Medical experimentation in Africa

MedlinePlus

MedlinePlus is an online information service produced by the United States National Library of Medicine.

See Medroxyprogesterone acetate and MedlinePlus

Medrogestone

Medrogestone, sold under the brand name Colprone among others, is a progestin medication which has been used in menopausal hormone therapy and in the treatment of gynecological disorders. Medroxyprogesterone acetate and Medrogestone are 3β-Hydroxysteroid dehydrogenase inhibitors, antigonadotropins, Diketones, glucocorticoids, pregnanes and progestogens.

See Medroxyprogesterone acetate and Medrogestone

Medroxyprogesterone

Medroxyprogesterone (MP), is a progestin which is not used medically. Medroxyprogesterone acetate and Medroxyprogesterone are Diketones, pregnanes and progestogens.

See Medroxyprogesterone acetate and Medroxyprogesterone

Megestrol acetate

Megestrol acetate (MGA), sold under the brand name Megace among others, is a progestin medication which is used mainly as an appetite stimulant to treat wasting syndromes such as cachexia. Medroxyprogesterone acetate and Megestrol acetate are acetate esters, anabolic–androgenic steroids, antigonadotropins, appetite stimulants, Diketones, drugs with unknown mechanisms of action, glucocorticoids, hormonal antineoplastic drugs, hormonal contraception, pregnanes, progestogen esters and progestogens.

See Medroxyprogesterone acetate and Megestrol acetate

Menarche

Menarche is the first menstrual cycle, or first menstrual bleeding, in female humans.

See Medroxyprogesterone acetate and Menarche

Menopause

Menopause, also known as the climacteric, is the time when menstrual periods permanently stop, marking the end of reproduction.

See Medroxyprogesterone acetate and Menopause

Menstrual disorder

A menstrual disorder is characterized as any abnormal condition with regards to a woman's menstrual cycle.

See Medroxyprogesterone acetate and Menstrual disorder

Menstruation

Menstruation (also known as a period, among other colloquial terms) is the regular discharge of blood and mucosal tissue from the inner lining of the uterus through the vagina.

See Medroxyprogesterone acetate and Menstruation

Merck Manual of Diagnosis and Therapy

The Merck Manual of Diagnosis and Therapy, referred to as The Merck Manual, is the world's best-selling medical textbook, and the oldest continuously published English language medical textbook.

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Meta-analysis

Meta-analysis is the statistical combination of the results of multiple studies addressing a similar research question.

See Medroxyprogesterone acetate and Meta-analysis

Metabolic pathway

In biochemistry, a metabolic pathway is a linked series of chemical reactions occurring within a cell.

See Medroxyprogesterone acetate and Metabolic pathway

Metabolism

Metabolism (from μεταβολή metabolē, "change") is the set of life-sustaining chemical reactions in organisms.

See Medroxyprogesterone acetate and Metabolism

Metabolite

In biochemistry, a metabolite is an intermediate or end product of metabolism.

See Medroxyprogesterone acetate and Metabolite

Metastasis

Metastasis is a pathogenic agent's spread from an initial or primary site to a different or secondary site within the host's body; the term is typically used when referring to metastasis by a cancerous tumor.

See Medroxyprogesterone acetate and Metastasis

Methyl group

In organic chemistry, a methyl group is an alkyl derived from methane, containing one carbon atom bonded to three hydrogen atoms, having chemical formula (whereas normal methane has the formula). In formulas, the group is often abbreviated as Me.

See Medroxyprogesterone acetate and Methyl group

Methylation

Methylation, in the chemical sciences, is the addition of a methyl group on a substrate, or the substitution of an atom (or group) by a methyl group.

See Medroxyprogesterone acetate and Methylation

Metribolone

Metribolone (developmental code R1881, also known as methyltrienolone) is a synthetic and orally active anabolic–androgenic steroid (AAS) and a 17α-alkylated nandrolone (19-nortestosterone) derivative which was never marketed for medical use but has been widely used in scientific research as a hot ligand in androgen receptor (AR) ligand binding assays (LBAs) and as a photoaffinity label for the AR. Medroxyprogesterone acetate and Metribolone are 3β-Hydroxysteroid dehydrogenase inhibitors, anabolic–androgenic steroids, glucocorticoids and progestogens.

See Medroxyprogesterone acetate and Metribolone

Microcrystalline

A microcrystalline material is a crystallized substance or rock that contains small crystals visible only through microscopic examination.

See Medroxyprogesterone acetate and Microcrystalline

Micronization

Micronization is the process of reducing the average diameter of a solid material's particles.

See Medroxyprogesterone acetate and Micronization

Migraine

Migraine is a genetically influenced complex neurological disorder characterized by episodes of moderate-to-severe headache, most often unilateral and generally associated with nausea and light and sound sensitivity.

See Medroxyprogesterone acetate and Migraine

Mineralocorticoid

Mineralocorticoids are a class of corticosteroids, which in turn are a class of steroid hormones.

See Medroxyprogesterone acetate and Mineralocorticoid

Mineralocorticoid receptor

The mineralocorticoid receptor (or MR, MLR, MCR), also known as the aldosterone receptor or nuclear receptor subfamily 3, group C, member 2, (NR3C2) is a protein that in humans is encoded by the NR3C2 gene that is located on chromosome 4q31.1-31.2.

See Medroxyprogesterone acetate and Mineralocorticoid receptor

Mineralocorticoid receptor antagonist

A mineralocorticoid receptor antagonist (MRA or MCRA) or aldosterone antagonist, is a diuretic drug which antagonizes the action of aldosterone at mineralocorticoid receptors.

See Medroxyprogesterone acetate and Mineralocorticoid receptor antagonist

Mittelschmerz

Mittelschmerz is a term for pain due to ovulation.

See Medroxyprogesterone acetate and Mittelschmerz

Mood (psychology)

In psychology, a mood is an affective state.

See Medroxyprogesterone acetate and Mood (psychology)

Mood swing

A mood swing is an extreme or sudden change of mood.

See Medroxyprogesterone acetate and Mood swing

Myocardial infarction

A myocardial infarction (MI), commonly known as a heart attack, occurs when blood flow decreases or stops in one of the coronary arteries of the heart, causing infarction (tissue death) to the heart muscle.

See Medroxyprogesterone acetate and Myocardial infarction

Nandrolone

Nandrolone, also known as 19-nortestosterone, is an endogenous androgen which exists in the male body at a ratio of 1:50 compared to testosterone. Medroxyprogesterone acetate and Nandrolone are anabolic–androgenic steroids, appetite stimulants and progestogens.

See Medroxyprogesterone acetate and Nandrolone

National Cancer Institute

The National Cancer Institute (NCI) coordinates the United States National Cancer Program and is part of the National Institutes of Health (NIH), which is one of eleven agencies that are part of the U.S. Department of Health and Human Services.

See Medroxyprogesterone acetate and National Cancer Institute

National Institute for Health and Care Excellence

The National Institute for Health and Care Excellence (NICE) is an executive non-departmental public body, in England, of the Department of Health and Social Care, that publishes guidelines in four areas.

See Medroxyprogesterone acetate and National Institute for Health and Care Excellence

National Women's Health Network

The National Women's Health Network (NWHN) is a non-profit women's health advocacy organization located in Washington, D.C. It was founded in 1975 by Barbara Seaman, Alice Wolfson, Belita Cowan, Mary Howell, and Phyllis Chesler.

See Medroxyprogesterone acetate and National Women's Health Network

Nausea

Nausea is a diffuse sensation of unease and discomfort, sometimes perceived as an urge to vomit.

See Medroxyprogesterone acetate and Nausea

Negative feedback

Negative feedback (or balancing feedback) occurs when some function of the output of a system, process, or mechanism is fed back in a manner that tends to reduce the fluctuations in the output, whether caused by changes in the input or by other disturbances.

See Medroxyprogesterone acetate and Negative feedback

Neuropeptide Y

Neuropeptide Y (NPY) is a 36 amino-acid neuropeptide that is involved in various physiological and homeostatic processes in both the central and peripheral nervous systems.

See Medroxyprogesterone acetate and Neuropeptide Y

Neurosteroid

Neurosteroids, also known as neuroactive steroids, are endogenous or exogenous steroids that rapidly alter neuronal excitability through interaction with ligand-gated ion channels and other cell surface receptors.

See Medroxyprogesterone acetate and Neurosteroid

Neutering

Neutering, from the Latin neuter ('of neither sex'), is the removal of a non-human animal's reproductive organ, either all of it or a considerably large part.

See Medroxyprogesterone acetate and Neutering

New Zealand

New Zealand (Aotearoa) is an island country in the southwestern Pacific Ocean.

See Medroxyprogesterone acetate and New Zealand

Nomegestrol acetate

Nomegestrol acetate (NOMAC), sold under the brand names Lutenyl and Zoely among others, is a progestin medication which is used in birth control pills, menopausal hormone therapy, and for the treatment of gynecological disorders. Medroxyprogesterone acetate and Nomegestrol acetate are acetate esters, antigonadotropins, Diketones, hormonal contraception, progestogen esters and progestogens.

See Medroxyprogesterone acetate and Nomegestrol acetate

Norethisterone

Norethisterone, also known as norethindrone and sold under many brand names, is a progestin medication used in birth control pills, menopausal hormone therapy, and for the treatment of gynecological disorders. Medroxyprogesterone acetate and Norethisterone are 3β-Hydroxysteroid dehydrogenase inhibitors, anabolic–androgenic steroids, hormonal contraception and progestogens.

See Medroxyprogesterone acetate and Norethisterone

Norethisterone acetate

Norethisterone acetate (NETA), also known as norethindrone acetate and sold under the brand name Primolut-Nor among others, is a progestin medication which is used in birth control pills, menopausal hormone therapy, and for the treatment of gynecological disorders. Medroxyprogesterone acetate and Norethisterone acetate are acetate esters, anabolic–androgenic steroids, antigonadotropins, hormonal contraception and progestogen esters.

See Medroxyprogesterone acetate and Norethisterone acetate

Oral administration

| name.

See Medroxyprogesterone acetate and Oral administration

Oral contraceptive pill

Oral contraceptives, abbreviated OCPs, also known as birth control pills, are medications taken by mouth for the purpose of birth control. Medroxyprogesterone acetate and Oral contraceptive pill are hormonal contraception.

See Medroxyprogesterone acetate and Oral contraceptive pill

Organic compound

Some chemical authorities define an organic compound as a chemical compound that contains a carbon–hydrogen or carbon–carbon bond; others consider an organic compound to be any chemical compound that contains carbon.

See Medroxyprogesterone acetate and Organic compound

Osteoporosis

Osteoporosis is a systemic skeletal disorder characterized by low bone mass, micro-architectural deterioration of bone tissue leading to more porous bone, and consequent increase in fracture risk.

See Medroxyprogesterone acetate and Osteoporosis

Ovarian cyst

An ovarian cyst is a fluid-filled sac within the ovary.

See Medroxyprogesterone acetate and Ovarian cyst

Ovulation

Ovulation is the release of eggs from the ovaries.

See Medroxyprogesterone acetate and Ovulation

Palliative care

Palliative care (derived from the Latin root, or 'to cloak') is an interdisciplinary medical caregiving approach aimed at optimizing quality of life and mitigating suffering among people with serious, complex, and often terminal illnesses.

See Medroxyprogesterone acetate and Palliative care

Paraphilia

A paraphilia is an experience of recurring or intense sexual arousal to atypical objects, places, situations, fantasies, behaviors, or individuals.

See Medroxyprogesterone acetate and Paraphilia

Particle size

Particle size is a notion introduced for comparing dimensions of solid particles (flecks), liquid particles (droplets), or gaseous particles (bubbles).

See Medroxyprogesterone acetate and Particle size

Pelvic inflammatory disease

Pelvic inflammatory disease, also known as pelvic inflammatory disorder (PID), is an infection of the upper part of the female reproductive system, namely the uterus, fallopian tubes, and ovaries, and inside of the pelvis.

See Medroxyprogesterone acetate and Pelvic inflammatory disease

PGRMC1

Progesterone receptor membrane component 1 (abbreviated PGRMC1) is a protein which co-purifies with progesterone binding proteins in the liver and ovary.

See Medroxyprogesterone acetate and PGRMC1

Pharmaceutical manufacturing

Pharmaceutical manufacturing is the process of industrial-scale synthesis of pharmaceutical drugs as part of the pharmaceutical industry.

See Medroxyprogesterone acetate and Pharmaceutical manufacturing

Pharmacodynamics

Pharmacodynamics (PD) is the study of the biochemical and physiologic effects of drugs (especially pharmaceutical drugs).

See Medroxyprogesterone acetate and Pharmacodynamics

Pharmacokinetics

Pharmacokinetics (from Ancient Greek pharmakon "drug" and kinetikos "moving, putting in motion"; see chemical kinetics), sometimes abbreviated as PK, is a branch of pharmacology dedicated to describing how the body affects a specific substance after administration.

See Medroxyprogesterone acetate and Pharmacokinetics

Pharmacovigilance

Pharmacovigilance (PV, or PhV), also known as drug safety, is the pharmaceutical science relating to the "collection, detection, assessment, monitoring, and prevention" of adverse effects with pharmaceutical products.

See Medroxyprogesterone acetate and Pharmacovigilance

Pituitary gland

The pituitary gland or hypophysis is an endocrine gland in vertebrates.

See Medroxyprogesterone acetate and Pituitary gland

Plasma protein binding

Plasma protein binding refers to the degree to which medications attach to blood proteins within the blood plasma.

See Medroxyprogesterone acetate and Plasma protein binding

Polyestradiol phosphate

Polyestradiol phosphate (PEP), sold under the brand name Estradurin, is an estrogen medication which is used primarily in the treatment of prostate cancer in men. Medroxyprogesterone acetate and Polyestradiol phosphate are antigonadotropins and hormonal antineoplastic drugs.

See Medroxyprogesterone acetate and Polyestradiol phosphate

Polyestradiol phosphate/medroxyprogesterone acetate

Polyestradiol phosphate/medroxyprogesterone acetate (PEP/MPA) is a combination of polyestradiol phosphate (PEP), an estrogen, and medroxyprogesterone acetate (MPA), a progestin, which was studied in the 1960s as a long-lasting combined injectable contraceptive for women but was never marketed.

See Medroxyprogesterone acetate and Polyestradiol phosphate/medroxyprogesterone acetate

Positive feedback

Positive feedback (exacerbating feedback, self-reinforcing feedback) is a process that occurs in a feedback loop which exacerbates the effects of a small disturbance.

See Medroxyprogesterone acetate and Positive feedback

Postpartum period

The postpartum (or postnatal) period begins after childbirth and is typically considered to last for six weeks.

See Medroxyprogesterone acetate and Postpartum period

Precocious puberty

In medicine, precocious puberty is puberty occurring at an unusually early age.

See Medroxyprogesterone acetate and Precocious puberty

Pregnancy

Pregnancy is the time during which one or more offspring develops (gestates) inside a woman's uterus (womb).

See Medroxyprogesterone acetate and Pregnancy

Pregnane

Pregnane, also known as 17β-ethylandrostane or as 10β,13β-dimethyl-17β-ethylgonane, is a C21 steroid and, indirectly, a parent of progesterone. Medroxyprogesterone acetate and Pregnane are pregnanes.

See Medroxyprogesterone acetate and Pregnane

Pregnanolone

Pregnanolone, also known as eltanolone, is an endogenous inhibitory neurosteroid which is produced in the body from progesterone.

See Medroxyprogesterone acetate and Pregnanolone

Primary biliary cholangitis

Primary biliary cholangitis (PBC), previously known as primary biliary cirrhosis, is an autoimmune disease of the liver.

See Medroxyprogesterone acetate and Primary biliary cholangitis

Prodrug

A prodrug is a pharmacologically inactive medication or compound that, after intake, is metabolized (i.e., converted within the body) into a pharmacologically active drug.

See Medroxyprogesterone acetate and Prodrug

Progesterone

Progesterone (P4) is an endogenous steroid and progestogen sex hormone involved in the menstrual cycle, pregnancy, and embryogenesis of humans and other species. Medroxyprogesterone acetate and Progesterone are Diketones, glucocorticoids, pregnanes and progestogens.

See Medroxyprogesterone acetate and Progesterone

Progesterone (medication)

Progesterone (P4), sold under the brand name Prometrium among others, is a medication and naturally occurring steroid hormone. Medroxyprogesterone acetate and Progesterone (medication) are antigonadotropins, Diketones, glucocorticoids, pregnanes and progestogens.

See Medroxyprogesterone acetate and Progesterone (medication)

Progesterone receptor

The progesterone receptor (PR), also known as NR3C3 or nuclear receptor subfamily 3, group C, member 3, is a protein found inside cells. Medroxyprogesterone acetate and progesterone receptor are progestogens.

See Medroxyprogesterone acetate and Progesterone receptor

Progestogen (medication)

A progestogen, also referred to as a progestagen, gestagen, or gestogen, is a type of medication which produces effects similar to those of the natural female sex hormone progesterone in the body. Medroxyprogesterone acetate and progestogen (medication) are progestogens.

See Medroxyprogesterone acetate and Progestogen (medication)

Progestogen ester

A progestogen ester is an ester of a progestogen or progestin (a synthetic progestogen). Medroxyprogesterone acetate and progestogen ester are progestogen esters and progestogens.

See Medroxyprogesterone acetate and Progestogen ester

Progestogen-only contraception

Progestogen-only contraception (or progestin-only contraception) relies on progestogens alone to achieve contraception. Medroxyprogesterone acetate and progestogen-only contraception are hormonal contraception.

See Medroxyprogesterone acetate and Progestogen-only contraception

Progestogen-only injectable contraceptive

Progestogen-only injectable contraceptives (POICs) are a form of hormonal contraception and progestogen-only contraception that are administered by injection and providing long-lasting birth control. Medroxyprogesterone acetate and progestogen-only injectable contraceptive are hormonal contraception and progestogens.

See Medroxyprogesterone acetate and Progestogen-only injectable contraceptive

Progestogen-only pill

Progestogen-only pills (POPs), colloquially known as "mini pills", are a type of oral contraceptive that contain synthetic progestogens (progestins) and do not contain estrogens. Medroxyprogesterone acetate and progestogen-only pill are hormonal contraception and progestogens.

See Medroxyprogesterone acetate and Progestogen-only pill

Promegestone

Promegestone, sold under the brand name Surgestone, is a progestin medication which is used in menopausal hormone therapy and in the treatment of gynecological disorders. Medroxyprogesterone acetate and Promegestone are Diketones, glucocorticoids and progestogens.

See Medroxyprogesterone acetate and Promegestone

Prostate cancer

Prostate cancer is the uncontrolled growth of cells in the prostate, a gland in the male reproductive system below the bladder.

See Medroxyprogesterone acetate and Prostate cancer

Pulmonary embolism

Pulmonary embolism (PE) is a blockage of an artery in the lungs by a substance that has moved from elsewhere in the body through the bloodstream (embolism).

See Medroxyprogesterone acetate and Pulmonary embolism

Quality and Outcomes Framework

The Quality and Outcomes Framework (QOF) is a system for the performance management and payment of general practitioners (GPs) in the National Health Service (NHS) in England, Wales, Scotland and Northern Ireland.

See Medroxyprogesterone acetate and Quality and Outcomes Framework

Radioimmunoassay

A radioimmunoassay (RIA) is an immunoassay that uses radiolabeled molecules in a stepwise formation of immune complexes.

See Medroxyprogesterone acetate and Radioimmunoassay

Receptor antagonist

A receptor antagonist is a type of receptor ligand or drug that blocks or dampens a biological response by binding to and blocking a receptor rather than activating it like an agonist.

See Medroxyprogesterone acetate and Receptor antagonist

Rectal administration

Rectal administration (colloquially known as boofing or plugging) uses the rectum as a route of administration for medication and other fluids, which are absorbed by the rectum's blood vessels,The rectum has numerous blood vessels available to absorb drugs: upwards 2/3rds of the dose bypasses first-pass metabolism through systemic distribution and the rest is taken through the liver and metabolized via the hepatic portal system.

See Medroxyprogesterone acetate and Rectal administration

Recurrent miscarriage

Recurrent miscarriage or recurrent pregnancy loss (RPL) is the spontaneous loss of 2-3 pregnancies that is estimated to affect up to 5% of women.

See Medroxyprogesterone acetate and Recurrent miscarriage

Redox

Redox (reduction–oxidation or oxidation–reduction) is a type of chemical reaction in which the oxidation states of the reactants change.

See Medroxyprogesterone acetate and Redox

Rhesus macaque

The rhesus macaque (Macaca mulatta), colloquially rhesus monkey, is a species of Old World monkey.

See Medroxyprogesterone acetate and Rhesus macaque

Ross Prentice

Ross L. Prentice (born October 16, 1946) is a Canadian statistician known particularly for his contributions to survival analysis and statistical methods for epidemiology.

See Medroxyprogesterone acetate and Ross Prentice

Sedation

Sedation is the reduction of irritability or agitation by administration of sedative drugs, generally to facilitate a medical procedure or diagnostic procedure.

See Medroxyprogesterone acetate and Sedation

Seizure

A seizure is a period of symptoms due to abnormally excessive or synchronous neuronal activity in the brain.

See Medroxyprogesterone acetate and Seizure

Serum albumin

Serum albumin, often referred to simply as blood albumin, is an albumin (a type of globular protein) found in vertebrate blood.

See Medroxyprogesterone acetate and Serum albumin

Sex hormone

Sex hormones, also known as sex steroids, gonadocorticoids and gonadal steroids, are steroid hormones that interact with vertebrate steroid hormone receptors.

See Medroxyprogesterone acetate and Sex hormone

Sex hormone-binding globulin

Sex hormone-binding globulin (SHBG) or sex steroid-binding globulin (SSBG) is a glycoprotein that binds to androgens and estrogens.

See Medroxyprogesterone acetate and Sex hormone-binding globulin

Sex offender

A sex offender (sexual offender, sex abuser, or sexual abuser) is a person who has committed a sex crime.

See Medroxyprogesterone acetate and Sex offender

Sickle cell disease

Sickle cell disease (SCD), also simply called sickle cell, is a group of hemoglobin-related blood disorders typically inherited.

See Medroxyprogesterone acetate and Sickle cell disease

Side effect

In medicine, a side effect is an effect, whether therapeutic or adverse, that is unintended; although the term is predominantly employed to describe adverse effects, it can also apply to beneficial, but unintended, consequences of the use of a drug.

See Medroxyprogesterone acetate and Side effect

Somnolence

Somnolence (alternatively sleepiness or drowsiness) is a state of strong desire for sleep, or sleeping for unusually long periods (compare hypersomnia).

See Medroxyprogesterone acetate and Somnolence

Spermatozoon

A spermatozoon (also spelled spermatozoön;: spermatozoa) is a motile sperm cell, or moving form of the haploid cell that is the male gamete.

See Medroxyprogesterone acetate and Spermatozoon

Steroid

A steroid is an organic compound with four fused rings (designated A, B, C, and D) arranged in a specific molecular configuration.

See Medroxyprogesterone acetate and Steroid

Steroid diabetes

Steroid diabetes or steroid-induced diabetes is characterized as an unusual rise in blood sugar that is linked to the use of glucocorticoids in a patient who may or may not have had diabetes mellitus in the past.

See Medroxyprogesterone acetate and Steroid diabetes

Steroidal antiandrogen

A steroidal antiandrogen (SAA) is an antiandrogen with a steroidal chemical structure. Medroxyprogesterone acetate and steroidal antiandrogen are antigonadotropins and hormonal antineoplastic drugs.

See Medroxyprogesterone acetate and Steroidal antiandrogen

Stroke

Stroke (also known as a cerebrovascular accident (CVA) or brain attack) is a medical condition in which poor blood flow to the brain causes cell death.

See Medroxyprogesterone acetate and Stroke

Stroma (tissue)

Stroma is the part of a tissue or organ with a structural or connective role.

See Medroxyprogesterone acetate and Stroma (tissue)

Structural analog

A structural analog, also known as a chemical analog or simply an analog, is a compound having a structure similar to that of another compound, but differing from it in respect to a certain component.

See Medroxyprogesterone acetate and Structural analog

Subcutaneous administration

Subcutaneous administration is the insertion of medications beneath the skin either by injection or infusion.

See Medroxyprogesterone acetate and Subcutaneous administration

Sublingual administration

Sublingual (abbreviated SL), from the Latin for "under the tongue", refers to the pharmacological route of administration by which substances diffuse into the blood through tissues under the tongue.

See Medroxyprogesterone acetate and Sublingual administration

Surgery

Surgery is a medical specialty that uses manual and instrumental techniques to diagnose or treat pathological conditions (e.g., trauma, disease, injury, malignancy), to alter bodily functions (i.e., malabsorption created by bariatric surgery such as gastric bypass), to reconstruct or improve aesthetics and appearance (cosmetic surgery), or to remove unwanted tissues (body fat, glands, scars or skin tags) or foreign bodies.

See Medroxyprogesterone acetate and Surgery

Suspension (chemistry)

In chemistry, a suspension is a heterogeneous mixture of a fluid that contains solid particles sufficiently large for sedimentation.

See Medroxyprogesterone acetate and Suspension (chemistry)

Sweden

Sweden, formally the Kingdom of Sweden, is a Nordic country located on the Scandinavian Peninsula in Northern Europe.

See Medroxyprogesterone acetate and Sweden

Syntex

Laboratorios Syntex SA (later Syntex Laboratories, Inc.) was a pharmaceutical company formed in Mexico City in January 1944 by Russell Marker, Emeric Somlo, and Federico Lehmann to manufacture therapeutic steroids from the Mexican yams called cabeza de negro (Dioscorea mexicana) and Barbasco (Dioscorea composita).

See Medroxyprogesterone acetate and Syntex

Tablet (pharmacy)

A tablet (also known as a pill) is a pharmaceutical oral dosage form (oral solid dosage, or OSD) or solid unit dosage form.

See Medroxyprogesterone acetate and Tablet (pharmacy)

Teratology

Teratology is the study of abnormalities of physiological development in organisms during their life span.

See Medroxyprogesterone acetate and Teratology

Territory (animal)

In ethology, territory is the sociographical area that an animal consistently defends against conspecific competition (or, occasionally, against animals of other species) using agonistic behaviors or (less commonly) real physical aggression.

See Medroxyprogesterone acetate and Territory (animal)

Testicle

A testicle or testis (testes) is the male gonad in all bilaterians, including humans.

See Medroxyprogesterone acetate and Testicle

Testosterone (medication)

Testosterone (T) is a medication and naturally occurring steroid hormone. Medroxyprogesterone acetate and Testosterone (medication) are anabolic–androgenic steroids, hormonal antineoplastic drugs and world Health Organization essential medicines.

See Medroxyprogesterone acetate and Testosterone (medication)

Thailand

Thailand, officially the Kingdom of Thailand and historically known as Siam (the official name until 1939), is a country in Southeast Asia on the Indochinese Peninsula.

See Medroxyprogesterone acetate and Thailand

Thrombin receptor

There are three known thrombin receptors (ThrR), termed PAR1, PAR3 and PAR4 (PAR for protease-activated receptor).

See Medroxyprogesterone acetate and Thrombin receptor

Thrombosis

Thrombosis is the formation of a blood clot inside a blood vessel, obstructing the flow of blood through the circulatory system.

See Medroxyprogesterone acetate and Thrombosis

Thrombus

A thrombus (thrombi), colloquially called a blood clot, is the final product of the blood coagulation step in hemostasis.

See Medroxyprogesterone acetate and Thrombus

Tolerability

Tolerability refers to the degree to which overt adverse effects of a drug can be tolerated by a patient.

See Medroxyprogesterone acetate and Tolerability

Trademark distinctiveness

Trademark distinctiveness is an important concept in the law governing trademarks and service marks.

See Medroxyprogesterone acetate and Trademark distinctiveness

Trans woman

A trans woman (short for transgender woman) is a woman who was assigned male at birth.

See Medroxyprogesterone acetate and Trans woman

Transactivation

In the context of gene regulation: transactivation is the increased rate of gene expression triggered either by biological processes or by artificial means, through the expression of an intermediate transactivator protein.

See Medroxyprogesterone acetate and Transactivation

Transcortin

Transcortin, also known as corticosteroid-binding globulin (CBG) or serpin A6, is a protein produced in the liver in animals.

See Medroxyprogesterone acetate and Transcortin

Transcription (biology)

Transcription is the process of copying a segment of DNA into RNA.

See Medroxyprogesterone acetate and Transcription (biology)

Triglyceride

A triglyceride (from tri- and glyceride; also TG, triacylglycerol, TAG, or triacylglyceride) is an ester derived from glycerol and three fatty acids.

See Medroxyprogesterone acetate and Triglyceride

Tumor necrosis factor

Tumor necrosis factor (TNF, cachexin, or cachectin; formerly known as tumor necrosis factor alpha, TNFα or TNF-α) is a cytokine and member of the TNF superfamily, which consists of various transmembrane proteins with a homologous TNF domain.

See Medroxyprogesterone acetate and Tumor necrosis factor

Ulcerative colitis

Ulcerative colitis (UC) is one of the two types of inflammatory bowel disease (IBD), with the other type being Crohn's disease.

See Medroxyprogesterone acetate and Ulcerative colitis

United Kingdom

The United Kingdom of Great Britain and Northern Ireland, commonly known as the United Kingdom (UK) or Britain, is a country in Northwestern Europe, off the coast of the continental mainland.

See Medroxyprogesterone acetate and United Kingdom

United States

The United States of America (USA or U.S.A.), commonly known as the United States (US or U.S.) or America, is a country primarily located in North America.

See Medroxyprogesterone acetate and United States

University of Pennsylvania

The University of Pennsylvania, commonly referenced as Penn or UPenn, is a private Ivy League research university in Philadelphia, Pennsylvania, United States.

See Medroxyprogesterone acetate and University of Pennsylvania

Upjohn

The Upjohn Company was an American pharmaceutical manufacturing firm founded in 1886 in Hastings, Michigan, by Dr.

See Medroxyprogesterone acetate and Upjohn

Urine

Urine is a liquid by-product of metabolism in humans and in many other animals.

See Medroxyprogesterone acetate and Urine

Uterus

The uterus (from Latin uterus,: uteri) or womb is the organ in the reproductive system of most female mammals, including humans, that accommodates the embryonic and fetal development of one or more embryos until birth.

See Medroxyprogesterone acetate and Uterus

Vagina

In mammals and other animals, the vagina (vaginas or vaginae) is the elastic, muscular reproductive organ of the female genital tract.

See Medroxyprogesterone acetate and Vagina

Vaginal bleeding

Vaginal bleeding is any expulsion of blood from the vagina.

See Medroxyprogesterone acetate and Vaginal bleeding

Vancouver Coastal Health

Vancouver Coastal Health (VCH) is a regional health authority that provides health services including primary, secondary, tertiary and quaternary care, home and community care, mental health services, population and preventive health and addictions services in part of Greater Vancouver and the Coast Garibaldi area.

See Medroxyprogesterone acetate and Vancouver Coastal Health

Vascular disease

Vascular disease is a class of diseases of the vessels of the circulatory system in the body, including blood vessels – the arteries and veins, and the lymphatic vessels.

See Medroxyprogesterone acetate and Vascular disease

Venous thrombosis

Venous thrombosis is the blockage of a vein caused by a thrombus (blood clot).

See Medroxyprogesterone acetate and Venous thrombosis

Ventromedial nucleus of the hypothalamus

The ventromedial nucleus of the hypothalamus (VMN, VMH or ventromedial hypothalamus) is a nucleus of the hypothalamus.

See Medroxyprogesterone acetate and Ventromedial nucleus of the hypothalamus

Veterinary medicine

Veterinary medicine is the branch of medicine that deals with the prevention, management, diagnosis, and treatment of disease, disorder, and injury in non-human animals.

See Medroxyprogesterone acetate and Veterinary medicine

Viral hepatitis

Viral hepatitis is liver inflammation due to a viral infection.

See Medroxyprogesterone acetate and Viral hepatitis

Virilization

Virilization or masculinization is the biological development of adult male characteristics in young males or females.

See Medroxyprogesterone acetate and Virilization

Viscosity

The viscosity of a fluid is a measure of its resistance to deformation at a given rate.

See Medroxyprogesterone acetate and Viscosity

Vitamin B12 deficiency

Vitamin B12 deficiency, also known as cobalamin deficiency, is the medical condition in which the blood and tissue have a lower than normal level of vitamin B12.

See Medroxyprogesterone acetate and Vitamin B12 deficiency

Vomiting

Vomiting (also known as emesis and throwing up) is the involuntary, forceful expulsion of the contents of one's stomach through the mouth and sometimes the nose.

See Medroxyprogesterone acetate and Vomiting

WHO Model List of Essential Medicines

The WHO Model List of Essential Medicines (aka Essential Medicines List or EML), published by the World Health Organization (WHO), contains the medications considered to be most effective and safe to meet the most important needs in a health system. Medroxyprogesterone acetate and WHO Model List of Essential Medicines are world Health Organization essential medicines.

See Medroxyprogesterone acetate and WHO Model List of Essential Medicines

Women's Health Initiative

The Women's Health Initiative (WHI) was a series of clinical studies initiated by the U.S. National Institutes of Health (NIH) in 1991, to address major health issues causing morbidity and mortality in postmenopausal women.

See Medroxyprogesterone acetate and Women's Health Initiative

World Health Organization

The World Health Organization (WHO) is a specialized agency of the United Nations responsible for international public health.

See Medroxyprogesterone acetate and World Health Organization

Zimbabwe

Zimbabwe, relief map Zimbabwe, officially the Republic of Zimbabwe, is a landlocked country in Southern Africa, between the Zambezi and Limpopo Rivers, bordered by South Africa to the south, Botswana to the southwest, Zambia to the north, and Mozambique to the east.

See Medroxyprogesterone acetate and Zimbabwe

17α-Hydroxyprogesterone

17α-Hydroxyprogesterone (17α-OHP), also known as 17-OH progesterone (17-OHP), or hydroxyprogesterone (OHP), is an endogenous progestogen steroid hormone related to progesterone. Medroxyprogesterone acetate and 17α-Hydroxyprogesterone are Diketones, glucocorticoids, pregnanes and progestogens.

See Medroxyprogesterone acetate and 17α-Hydroxyprogesterone

3α-Androstanediol

3α-Androstanediol also known as 5α-androstane-3α,17β-diol and sometimes shortened in the literature to 3α-diol, is an endogenous steroid hormone and neurosteroid and a metabolite of androgens like dihydrotestosterone (DHT). Medroxyprogesterone acetate and 3α-Androstanediol are anabolic–androgenic steroids.

See Medroxyprogesterone acetate and 3α-Androstanediol

3α-Hydroxysteroid dehydrogenase

3α-Hydroxysteroid dehydrogenase (3α-HSD) is an enzyme (1.1.1.50) that plays a role in the metabolism of steroids and non-steroidal compounds in humans and other species, such as bacteria, fungi, plants, and so on.

See Medroxyprogesterone acetate and 3α-Hydroxysteroid dehydrogenase

3β-Hydroxysteroid dehydrogenase

3β-Hydroxysteroid dehydrogenase/Δ5-4 isomerase (3β-HSD) is an enzyme that catalyzes the biosynthesis of the steroid progesterone from pregnenolone, 17α-hydroxyprogesterone from 17α-hydroxypregnenolone, and androstenedione from dehydroepiandrosterone (DHEA) in the adrenal gland.

See Medroxyprogesterone acetate and 3β-Hydroxysteroid dehydrogenase

5α-Dihydroprogesterone

5α-Dihydroprogesterone (5α-DHP, allopregnanedione, or 5α-pregnane-3,20-dione) is an endogenous progestogen and neurosteroid that is synthesized from progesterone. Medroxyprogesterone acetate and 5α-Dihydroprogesterone are Diketones, pregnanes and progestogens.

See Medroxyprogesterone acetate and 5α-Dihydroprogesterone

5α-Reductase

5α-Reductases, also known as 3-oxo-5α-steroid 4-dehydrogenases, are enzymes involved in steroid metabolism.

See Medroxyprogesterone acetate and 5α-Reductase

5β-Dihydroprogesterone

5β-Dihydroprogesterone (5β-DHP, pregnanedione, or 5β-pregnane-3,20-dione) is an endogenous neurosteroid and an intermediate in the biosynthesis of pregnanolone and epipregnanolone from progesterone. Medroxyprogesterone acetate and 5β-Dihydroprogesterone are Diketones.

See Medroxyprogesterone acetate and 5β-Dihydroprogesterone

5β-Reductase

5β-Reductase, or Δ4-3-oxosteroid 5β-reductase (3-oxo-Δ4-steroid 5β-reductase, androstenedione 5β-reductase, cholestenone 5β-reductase, cortisone 5β-reductase, cortisone Δ4-5β-reductase, steroid 5β-reductase, testosterone 5β-reductase, Δ4-3-ketosteroid 5β-reductase, Δ4-5β-reductase, Δ4-hydrogenase, 4,5β-dihydrocortisone:NADP+ Δ4-oxidoreductase, 3-oxo-5β-steroid:NADP+ Δ4-oxidoreductase) is an enzyme with systematic name 5β-cholestan-3-one:NADP+ 4,5-oxidoreductase.

See Medroxyprogesterone acetate and 5β-Reductase

See also

3α-Hydroxysteroid dehydrogenase inhibitors

3β-Hydroxysteroid dehydrogenase inhibitors

Appetite stimulants

Feminizing hormone therapy

References

[1] https://en.wikipedia.org/wiki/Medroxyprogesterone_acetate

Also known as 17α-Hydroxy-6α-methylpregn-4-ene-3,20-dione acetate, 6α-Methyl-17α-acetoxyprogesterone, 6α-Methyl-17α-hydroxyprogesterone acetate, 6α-Methyl-3,20-dioxopregn-4-en-17α-yl acetate, ATC code G03AC06, ATC code G03DA02, ATC code L02AB02, ATCvet code QG03AC06, ATCvet code QG03DA02, ATCvet code QL02AB02, Acetato de medroxiprogesterona, Amen (drug), Aragest, Aragest 5, Asconale, Birth control shot, Clinofem, Clinovir, Colirest, Controlestril, Curretab, Cycrin, Depo Injection, Depo Provera, Depo shot, Depo-Clinovir, Depo-Prodasone, Depo-Progestin, Depo-Promone, Depo-Provera, Depomedroxy-progesterone acetate, Depot medroxyprogesterone, Depot medroxyprogesterone acetate, Deprovera, Farlutal, Farlutin, G-Farlutal, Gestapuran, Hematrol, Hysron, Lutopolar, Lutoral, MPA Gyn 5, Med-Pro, Medroksiprogesteron Asetat, Medroksiprogesteroniasetaatti, Medroksiprogesterono acetatas, Medroksyprogesteronu octan, Medroxiprogesteronacetat, Medroxiprogeszteron acetát, Medroxiprogeszteron-acetát, Medroxyhexal, Medroxyprogesteron acetát, Medroxyprogesteron-acetát, Medroxyprogesteronacetat, Medroxyprogesterone 17-acetate, Medroxyprogesteroni acetas, Megestron, Meprate, Methylacetoxyprogesterone, Methylhydroxyprogesterone acetate, Methylpregnone, Methypregnone, Metigesterona, Metigestrona, Metipregnone, Médroxyprogestérone (acétate de), Médroxyprogestérone acétate de, Médroxyprogestérone, acétate de, Nadigest, Nidaxin, Novo-Medrone, OMPA, Oragest, Oral medroxyprogesterone, Oral medroxyprogesterone acetate, Perlutex, Perlutex Leo, Prodasone, Progestalfa, Progevera, Proverone, Ralovera, Repromap, Repromix, Sirprogen, Sodelut G, The jag, Veramix.

, Biological target, Biosynthesis, Biotransformation, Bipolar disorder, Birth control, Birth defect, Blood vessel, Bone density, Boxed warning, Breast cancer, Breast pain, Breastfeeding, Calcium channel, Cancer, Carcinogen, Cardiovascular disease, Catamenial epilepsy, Cell (biology), Cell proliferation, Cervix, Chemical castration, Chlormadinone acetate, Cholesterol side-chain cleavage enzyme, Cirrhosis, Class action, Clinical trial, Coagulation, Cognitive impairment, Colorectal cancer, Combined injectable birth control, Combined oral contraceptive pill, Competitive inhibition, Conjugated estrogens, Conjugated estrogens/medroxyprogesterone acetate, Coronary artery disease, Corticosteroid, Cortisol, Crohn's disease, Cushing's syndrome, CYP17A1, CYP3A4, Cyproterone acetate, Cytokine, Decidualization, Deep vein thrombosis, Dementia, Deoxycorticosterone, Depot injection, Depression (mood), Derivative (chemistry), Developing country, Dexamethasone, Diabetes, Diabetic nephropathy, Diabetic neuropathy, Diabetic retinopathy, Diana Miglioretti, Diethylstilbestrol, Dihydrotestosterone, Dissociation constant, Dizziness, Downregulation and upregulation, Drug interaction, Dydrogesterone, Dysmenorrhea, Dysuria, EC50, Ectopic pregnancy, Edema, Ejaculation, Elimination (pharmacology), Elsevier, Endometrial cancer, Endometrial hyperplasia, Endometriosis, Endometrium, Enzyme, Enzyme induction and inhibition, Enzyme inhibitor, Epilepsy, Epithelium, Erectile dysfunction, Ester, Estradiol, Estradiol (medication), Estradiol cypionate, Estradiol cypionate/medroxyprogesterone acetate, Estradiol valerate, Estradiol/medroxyprogesterone acetate, Estrogen, Estrogen (medication), Estrogen receptor, Estrogen-dependent condition, Ethinylestradiol, Excretion, Familial male-limited precocious puberty, Fatigue, Feces, Feminizing hormone therapy, Fertilisation, Fertility, Fetus, Fibrinolysis, Flunitrazepam, Fluorine, Fluoromedroxyprogesterone acetate, Follicle-stimulating hormone, Follicular phase, 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Ventromedial nucleus of the hypothalamus, Veterinary medicine, Viral hepatitis, Virilization, Viscosity, Vitamin B12 deficiency, Vomiting, WHO Model List of Essential Medicines, Women's Health Initiative, World Health Organization, Zimbabwe, 17α-Hydroxyprogesterone, 3α-Androstanediol, 3α-Hydroxysteroid dehydrogenase, 3β-Hydroxysteroid dehydrogenase, 5α-Dihydroprogesterone, 5α-Reductase, 5β-Dihydroprogesterone, 5β-Reductase.