Logo
Unionpedia
Communication
Get it on Google Play
New! Download Unionpedia on your Android™ device!
Install
Faster access than browser!
 

MK-386

Index MK-386

MK-386, also known as 4,7β-dimethyl-4-aza-5α-cholestan-3-one, is a synthetic, steroidal 5α-reductase inhibitor which was first reported in 1994 and was never marketed. [1]

26 relations: Acne, Androgen-dependent condition, Antibiotic, Azasteroid, Binding selectivity, Clinical trial, Dihydrotestosterone, Dutasteride, Elevated transaminases, Enzyme inhibitor, Finasteride, Hepatotoxicity, IC50, Minocycline, Oral administration, Organic compound, Pattern hair loss, Placebo, Potency (pharmacology), Sebaceous gland, Semen, SRD5A1, SRD5A2, Steroid, 5α-Reductase, 5α-Reductase inhibitor.

Acne

Acne, also known as acne vulgaris, is a long-term skin disease that occurs when hair follicles are clogged with dead skin cells and oil from the skin.

New!!: MK-386 and Acne · See more »

Androgen-dependent condition

An androgen-dependent condition, disease, disorder, or syndrome, is a medical condition that is, in part or full, dependent on, or is sensitive to, the presence of androgenic activity in the body.

New!!: MK-386 and Androgen-dependent condition · See more »

Antibiotic

An antibiotic (from ancient Greek αντιβιοτικά, antibiotiká), also called an antibacterial, is a type of antimicrobial drug used in the treatment and prevention of bacterial infections.

New!!: MK-386 and Antibiotic · See more »

Azasteroid

An azasteroid is a type of steroid derivative which has one of the carbon atoms in the steroid ring system replaced by a nitrogen atom.

New!!: MK-386 and Azasteroid · See more »

Binding selectivity

Binding selectivity is defined with respect to the binding of ligands to a substrate forming a complex.

New!!: MK-386 and Binding selectivity · See more »

Clinical trial

Clinical trials are experiments or observations done in clinical research.

New!!: MK-386 and Clinical trial · See more »

Dihydrotestosterone

Dihydrotestosterone (DHT), or 5α-dihydrotestosterone (5α-DHT), also known as androstanolone or stanolone, is an endogenous androgen sex steroid and hormone.

New!!: MK-386 and Dihydrotestosterone · See more »

Dutasteride

Dutasteride, sold under the brand name Avodart among others, is a medication used primarily to treat enlarged prostate in men.

New!!: MK-386 and Dutasteride · See more »

Elevated transaminases

In medicine, the presence of elevated transaminases, commonly the transaminases alanine transaminase (ALT) and aspartate transaminase (AST), may be an indicator of liver damage.

New!!: MK-386 and Elevated transaminases · See more »

Enzyme inhibitor

4QI9) An enzyme inhibitor is a molecule that binds to an enzyme and decreases its activity.

New!!: MK-386 and Enzyme inhibitor · See more »

Finasteride

Finasteride, sold under the brand names Proscar and Propecia among others, is a medication used mainly to treat an enlarged prostate or scalp hair loss in men.

New!!: MK-386 and Finasteride · See more »

Hepatotoxicity

Hepatotoxicity (from hepatic toxicity) implies chemical-driven liver damage.

New!!: MK-386 and Hepatotoxicity · See more »

IC50

The half maximal inhibitory concentration (IC50) is a measure of the potency of a substance in inhibiting a specific biological or biochemical function.

New!!: MK-386 and IC50 · See more »

Minocycline

Minocycline is a broad-spectrum tetracycline antibiotic, and has a broader spectrum than the other members of the group.

New!!: MK-386 and Minocycline · See more »

Oral administration

| name.

New!!: MK-386 and Oral administration · See more »

Organic compound

In chemistry, an organic compound is generally any chemical compound that contains carbon.

New!!: MK-386 and Organic compound · See more »

Pattern hair loss

Pattern hair loss, known as male-pattern hair loss (MPHL) when it affects males and female-pattern hair loss (FPHL) when it affects females, is hair loss that primarily affects the top and front of the scalp.

New!!: MK-386 and Pattern hair loss · See more »

Placebo

A placebo is a substance or treatment of no intended therapeutic value.

New!!: MK-386 and Placebo · See more »

Potency (pharmacology)

In the field of pharmacology, potency is a measure of drug activity expressed in terms of the amount required to produce an effect of given intensity.

New!!: MK-386 and Potency (pharmacology) · See more »

Sebaceous gland

Sebaceous glands are microscopic exocrine glands in the skin that secrete an oily or waxy matter, called sebum, to lubricate and waterproof the skin and hair of mammals.

New!!: MK-386 and Sebaceous gland · See more »

Semen

Semen, also known as seminal fluid, is an organic fluid that may contain spermatozoa.

New!!: MK-386 and Semen · See more »

SRD5A1

3-oxo-5α-steroid 4-dehydrogenase 1 is an enzyme that in humans is encoded by the SRD5A1 gene.

New!!: MK-386 and SRD5A1 · See more »

SRD5A2

3-oxo-5α-steroid 4-dehydrogenase 2 is an enzyme that in humans is encoded by the SRD5A2 gene.

New!!: MK-386 and SRD5A2 · See more »

Steroid

A steroid is a biologically active organic compound with four rings arranged in a specific molecular configuration.

New!!: MK-386 and Steroid · See more »

5α-Reductase

5α-reductases, also known as 3-oxo-5α-steroid 4-dehydrogenases, are enzymes involved in steroid metabolism.

New!!: MK-386 and 5α-Reductase · See more »

5α-Reductase inhibitor

5α-Reductase inhibitors (5-ARIs), also known as dihydrotestosterone (DHT) blockers, are a class of medications with antiandrogenic effects which are used primarily in the treatment of enlarged prostate and scalp hair loss.

New!!: MK-386 and 5α-Reductase inhibitor · See more »

Redirects here:

L 733,692, L 733692, L-733,692, L-733692, L733692, MK 386, MK386.

References

[1] https://en.wikipedia.org/wiki/MK-386

OutgoingIncoming
Hey! We are on Facebook now! »