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Vascular endothelial growth factor A

Index Vascular endothelial growth factor A

Vascular endothelial growth factor A (VEGF-A) is a protein that in humans is encoded by the VEGFA gene. [1]

41 relations: ADAMTS1, Alternative splicing, Angiogenesis, Apoptosis, Bevacizumab, Cardiomyopathy, Cell migration, Chemotaxis, CTGF, Diabetic retinopathy, Endothelium, Fenestra, Gene, Glycosylation, Granulocyte, Kinase insert domain receptor, Lumen (anatomy), Macrophage, MAPK1, Matrix metalloproteinase, Mitogen, Mitogen-activated protein kinase, Mitosis, Monocyte, NCK1, Neuropilin 1, Nitric oxide, P38 mitogen-activated protein kinases, Phosphorylation, Platelet-derived growth factor, PLCG1, POEMS syndrome, Protein, Protein kinase C, Protein–protein interaction, SH2D2A, Tyrosine kinase, Vascular endothelial growth factor, Vasculogenesis, Vasodilation, VEGFR1.

ADAMTS1

A disintegrin and metalloproteinase with thrombospondin motifs 1 is an enzyme that in humans is encoded by the ADAMTS1 gene.

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Alternative splicing

Alternative splicing, or differential splicing, is a regulated process during gene expression that results in a single gene coding for multiple proteins.

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Angiogenesis

Angiogenesis is the physiological process through which new blood vessels form from pre-existing vessels.

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Apoptosis

Apoptosis (from Ancient Greek ἀπόπτωσις "falling off") is a process of programmed cell death that occurs in multicellular organisms.

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Bevacizumab

Bevacizumab, sold under the trade name Avastin, is medication used to treat a number of types of cancers and a specific eye disease.

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Cardiomyopathy

Cardiomyopathy is a group of diseases that affect the heart muscle.

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Cell migration

Cell migration is a central process in the development and maintenance of multicellular organisms.

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Chemotaxis

Chemotaxis (from chemo- + taxis) is the movement of an organism in response to a chemical stimulus.

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CTGF

CTGF, also known as CCN2 or connective tissue growth factor, is a matricellular protein of the CCN family of extracellular matrix-associated heparin-binding proteins (see also CCN intercellular signaling protein).

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Diabetic retinopathy

Diabetic retinopathy, also known as diabetic eye disease, is a medical condition in which damage occurs to the retina due to diabetes mellitus.

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Endothelium

Endothelium refers to cells that line the interior surface of blood vessels and lymphatic vessels, forming an interface between circulating blood or lymph in the lumen and the rest of the vessel wall.

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Fenestra

A fenestra (plural fenestrae) in anatomy, zoology and biology, is any small opening or pore.

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Gene

In biology, a gene is a sequence of DNA or RNA that codes for a molecule that has a function.

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Glycosylation

Glycosylation (see also chemical glycosylation) is the reaction in which a carbohydrate, i.e. a glycosyl donor, is attached to a hydroxyl or other functional group of another molecule (a glycosyl acceptor).

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Granulocyte

Granulocytes are a category of white blood cells characterized by the presence of granules in their cytoplasm.

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Kinase insert domain receptor

Kinase insert domain receptor (KDR, a type III receptor tyrosine kinase) also known as vascular endothelial growth factor receptor 2 (VEGFR-2) is a VEGF receptor.

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Lumen (anatomy)

In biology, a lumen (plural lumina) is the inside space of a tubular structure, such as an artery or intestine.

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Macrophage

Macrophages (big eaters, from Greek μακρός (makrós).

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MAPK1

Mitogen-activated protein kinase 1, also known as MAPK1, p42MAPK, and ERK2, is an enzyme that in humans is encoded by the MAPK1 gene.

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Matrix metalloproteinase

Matrix metalloproteinases (MMPs), also known as matrixins, are calcium-dependent zinc-containing endopeptidases; other family members are adamalysins, serralysins, and astacins.

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Mitogen

A mitogen is a chemical substance that encourages a cell to commence cell division, triggering mitosis.

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Mitogen-activated protein kinase

A mitogen-activated protein kinase (MAPK or MAP kinase) is a type of protein kinase that is specific to the amino acids serine and threonine (i.e., a serine/threonine-specific protein kinase).

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Mitosis

In cell biology, mitosis is a part of the cell cycle when replicated chromosomes are separated into two new nuclei.

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Monocyte

Monocytes are a type of leukocyte, or white blood cell.

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NCK1

Cytoplasmic protein NCK1 is a protein that in humans is encoded by the NCK1 gene.

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Neuropilin 1

Neuropilin-1 is a protein that in humans is encoded by the NRP1 gene.

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Nitric oxide

Nitric oxide (nitrogen oxide or nitrogen monoxide) is a colorless gas with the formula NO.

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P38 mitogen-activated protein kinases

P38 mitogen-activated protein kinases are a class of mitogen-activated protein kinases (MAPKs) that are responsive to stress stimuli, such as cytokines, ultraviolet irradiation, heat shock, and osmotic shock, and are involved in cell differentiation, apoptosis and autophagy.

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Phosphorylation

In chemistry, phosphorylation of a molecule is the attachment of a phosphoryl group.

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Platelet-derived growth factor

Platelet-derived growth factor (PDGF) is one of numerous growth factors that regulate cell growth and division.

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PLCG1

Phospholipase C, gamma 1, also known as PLCG1, is a protein that in humans is encoded by the PLCG1 gene.

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POEMS syndrome

POEMS syndrome (also termed osteosclerotic myeloma, Crow–Fukase syndrome, Takatsuki disease, or PEP syndrome) is a rare paraneoplastic syndrome caused by a clone of aberrant plasma cells.

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Protein

Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.

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Protein kinase C

Protein kinase C, commonly abbreviated to PKC (EC 2.7.11.13), is a family of protein kinase enzymes that are involved in controlling the function of other proteins through the phosphorylation of hydroxyl groups of serine and threonine amino acid residues on these proteins, or a member of this family.

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Protein–protein interaction

Protein–protein interactions (PPIs) are the physical contacts of high specificity established between two or more protein molecules as a result of biochemical events steered by electrostatic forces including the hydrophobic effect.

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SH2D2A

SH2 domain-containing protein 2A is a protein that in humans is encoded by the SH2D2A gene.

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Tyrosine kinase

A tyrosine kinase is an enzyme that can transfer a phosphate group from ATP to a protein in a cell.

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Vascular endothelial growth factor

Vascular endothelial growth factor (VEGF), originally known as vascular permeability factor (VPF), is a signal protein produced by cells that stimulates the formation of blood vessels.

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Vasculogenesis

Vasculogenesis is the process of blood vessel formation occurring by a de novo production of endothelial cells.

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Vasodilation

Vasodilation is the widening of blood vessels.

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VEGFR1

Vascular endothelial growth factor receptor 1 is a protein that in humans is encoded by the FLT1 gene.

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Redirects here:

VEGF-A, VEGFA, VEGFA (gene), Vascular endothelial growth factor a.

References

[1] https://en.wikipedia.org/wiki/Vascular_endothelial_growth_factor_A

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