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Human blood group systems

Index Human blood group systems

The term human blood group systems is defined by International Society of Blood Transfusion as systems in the human species where cell-surface antigens—in particular, those on blood cells—are "controlled at a single gene locus or by two or more very closely linked homologous genes with little or no observable recombination between them", and include the common ABO and Rh- (Rhesus) antigen systems, as well as many others; thirty-five major human systems are identified as of November 2014. [1]

87 relations: ABCB6, ABCG2, ABO blood group system, Acetylcholinesterase, Antibody, Antigen, Aquaporin 1, Aquaporin 3, ART4, Augustine of Hippo, Band 3, Basigin, BGMUT, Blood plasma, CD151, CD44, CD59, Chemokine receptor, Chromosome, Chromosome 1, Chromosome 11, Chromosome 12, Chromosome 15, Chromosome 17, Chromosome 18, Chromosome 19, Chromosome 2, Chromosome 22, Chromosome 3, Chromosome 4, Chromosome 6, Chromosome 7, Chromosome 9, Colton antigen system, Complement component 4, Complement receptor 1, Decay-accelerating factor, Diego antigen system, Duffy antigen system, East Asia, Epitope, ERMAP, Fucose, Galactose, GBGT1, Genetic recombination, Glycolipid, Glycophorin, Glycophorin C, Glycosylphosphatidylinositol, ..., Hemolytic disease of the newborn (anti-Kell), Hh blood group, Human red cell antigens, ICAM4, Ii antigen system, Immunoglobulin M, Immunoglobulin superfamily, Indian blood group system, Indigenous peoples of the Americas, International Society of Blood Transfusion, Kell antigen system, Kidd antigen system, Lewis antigen system, Locus (genetics), Lutheran antigen system, Malaria, MNS antigen system, N-Acetylgalactosamine, National Center for Biotechnology Information, National Institutes of Health, Oligosaccharide, P antigen system, Plasmodium knowlesi, Plasmodium vivax, Platelet, Polysaccharide, Porphyrin, Red blood cell, Rh blood group system, RHAG, SEMA7A, Sequence homology, White blood cell, X chromosome, Xg antigen system, XK (protein), Yt antigen system. Expand index (37 more) »

ABCB6

ATP-binding cassette sub-family B member 6, mitochondrial is a protein that in humans is encoded by the ABCB6 gene.

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ABCG2

ATP-binding cassette sub-family G member 2 is a protein that in humans is encoded by the ABCG2 gene.

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ABO blood group system

The ABO blood group system is used to denote the presence of one, both, or neither of the A and B antigens on erythrocytes.

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Acetylcholinesterase

Acetylcholinesterase, encoded by HGNC gene ACHE; EC 3.1.1.7) is the primary cholinesterase in the body. It is an enzyme that catalyzes the breakdown of acetylcholine and of some other choline esters that function as neurotransmitters. AChE is found at mainly neuromuscular junctions and in chemical synapses of the cholinergic type, where its activity serves to terminate synaptic transmission. It belongs to carboxylesterase family of enzymes. It is the primary target of inhibition by organophosphorus compounds such as nerve agents and pesticides.

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Antibody

An antibody (Ab), also known as an immunoglobulin (Ig), is a large, Y-shaped protein produced mainly by plasma cells that is used by the immune system to neutralize pathogens such as pathogenic bacteria and viruses.

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Antigen

In immunology, an antigen is a molecule capable of inducing an immune response (to produce an antibody) in the host organism.

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Aquaporin 1

Aquaporin 1 is a protein that in humans is encoded by the AQP1 gene.

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Aquaporin 3

Aquaporin 3 is found in the basolateral cell membrane of principal collecting duct cells and provides a pathway for water to exit these cells.

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ART4

Ecto-ADP-ribosyltransferase 4 is an enzyme that in humans is encoded by the ART4 gene.

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Augustine of Hippo

Saint Augustine of Hippo (13 November 354 – 28 August 430) was a Roman African, early Christian theologian and philosopher from Numidia whose writings influenced the development of Western Christianity and Western philosophy.

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Band 3

Band 3 anion transport protein, also known as anion exchanger 1 (AE1) or band 3 or solute carrier family 4 member 1 (SLC4A1), is a protein that is encoded by the SLC4A1 gene in humans.

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Basigin

Basigin (BSG) also known as extracellular matrix metalloproteinase inducer (EMMPRIN) or cluster of differentiation 147 (CD147) is a protein that in humans is encoded by the BSG gene.

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BGMUT

The BGMUT (Blood Group antigen gene MUTation) Database documents allelic variations in the genes encoding for human blood group systems.

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Blood plasma

Blood plasma is a yellowish coloured liquid component of blood that normally holds the blood cells in whole blood in suspension; this makes plasma the extracellular matrix of blood cells.

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CD151

CD151 molecule (Raph blood group), also known as CD151 (Cluster of Differentiation 151), is a human gene.

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CD44

The CD44 antigen is a cell-surface glycoprotein involved in cell–cell interactions, cell adhesion and migration.

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CD59

CD59 glycoprotein, also known as MAC-inhibitory protein (MAC-IP), membrane inhibitor of reactive lysis (MIRL), or protectin, is a protein that in humans is encoded by the CD59 gene.

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Chemokine receptor

Chemokine receptors are cytokine receptors found on the surface of certain cells that interact with a type of cytokine called a chemokine.

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Chromosome

A chromosome (from Ancient Greek: χρωμόσωμα, chromosoma, chroma means colour, soma means body) is a DNA molecule with part or all of the genetic material (genome) of an organism.

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Chromosome 1

Chromosome 1 is the designation for the largest human chromosome.

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Chromosome 11

Chromosome 11 is one of the 23 pairs of chromosomes in humans.

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Chromosome 12

Chromosome 12 is one of the 23 pairs of chromosomes in humans.

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Chromosome 15

Chromosome 15 is one of the 23 pairs of chromosomes in humans.

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Chromosome 17

Chromosome 17 is one of the 23 pairs of chromosomes in humans.

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Chromosome 18

Chromosome 18 is one of the 23 pairs of chromosomes in humans.

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Chromosome 19

Chromosome 19 is one of the 23 pairs of chromosomes in humans.

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Chromosome 2

Chromosome 2 is one of the 23 pairs of chromosomes in humans.

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Chromosome 22

Chromosome 22 is one of the 23 pairs of chromosomes in human cells.

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Chromosome 3

Chromosome 3 is one of the 23 pairs of chromosomes in humans.

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Chromosome 4

Chromosome 4 is one of the 23 pairs of chromosomes in humans.

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Chromosome 6

Chromosome 6 is one of the 23 pairs of chromosomes in humans.

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Chromosome 7

Chromosome 7 is one of the 23 pairs of chromosomes in humans.

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Chromosome 9

Chromosome 9 is one of the 23 pairs of chromosomes in humans.

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Colton antigen system

The Colton antigen system (Co) is present on the membranes of red blood cells and in the tubules of the kidney and helps determine a person's blood type.

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Complement component 4

Complement component 4 (C4), in humans, is a protein involved in the intricate complement system, originating from the human leukocyte antigen (HLA) system.

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Complement receptor 1

Complement receptor type 1 (CR1) also known as C3b/C4b receptor or CD35 (cluster of differentiation 35) is a protein that in humans is encoded by the CR1 gene.

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Decay-accelerating factor

Complement decay-accelerating factor, also known as CD55 or DAF, is a protein that, in humans, is encoded by the CD55 gene.

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Diego antigen system

The Diego antigen (or blood group) system is composed of 21 blood factors or antigens carried on the Band 3 glycoprotein, also known as Anion Exchanger 1 (AE1).

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Duffy antigen system

Duffy antigen/chemokine receptor (DARC), also known as Fy glycoprotein (FY) or CD234 (Cluster of Differentiation 234), is a protein that in humans is encoded by the DARC gene.

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East Asia

East Asia is the eastern subregion of the Asian continent, which can be defined in either geographical or ethno-cultural "The East Asian cultural sphere evolves when Japan, Korea, and what is today Vietnam all share adapted elements of Chinese civilization of this period (that of the Tang dynasty), in particular Buddhism, Confucian social and political values, and literary Chinese and its writing system." terms.

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Epitope

An epitope, also known as antigenic determinant, is the part of an antigen that is recognized by the immune system, specifically by antibodies, B cells, or T cells.

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ERMAP

Erythroid membrane-associated protein is a protein that in humans is responsible for the Scianna blood group system, and is encoded by the ERMAP gene.

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Fucose

Fucose is a hexose deoxy sugar with the chemical formula C6H12O5.

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Galactose

Galactose (galacto- + -ose, "milk sugar"), sometimes abbreviated Gal, is a monosaccharide sugar that is about as sweet as glucose, and about 30% as sweet as sucrose.

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GBGT1

Globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 is an enzyme that in humans is encoded by the GBGT1 gene.

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Genetic recombination

Genetic recombination (aka genetic reshuffling) is the production of offspring with combinations of traits that differ from those found in either parent.

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Glycolipid

Glycolipids are lipids with a carbohydrate attached by a glycosidic bond or covalently bonded.

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Glycophorin

A glycophorin is a sialoglycoprotein of the membrane of a red blood cell.

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Glycophorin C

Glycophorin C (GYPC; CD236/CD236R; glycoprotein beta; glycoconnectin; PAS-2) plays a functionally important role in maintaining erythrocyte shape and regulating membrane material properties, possibly through its interaction with protein 4.1.

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Glycosylphosphatidylinositol

Glycosylphosphatidylinositol, or glycophosphatidylinositol, or GPI in short, is a glycolipid that can be attached to the C-terminus of a protein during posttranslational modification.

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Hemolytic disease of the newborn (anti-Kell)

Hemolytic disease of the newborn (anti-Kell1) is the second most common cause of severe hemolytic disease of the newborn (HDN) after Rh disease.

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Hh blood group

The h/h blood group, also known as Oh or the Bombay blood group, is a rare blood type.

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Human red cell antigens

In addition to the defined human blood group systems, there are erythrocyte antigens which do not meet the definition of a blood group system.

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ICAM4

The LW blood system was first described by Landsteiner and Wiener in 1940.

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Ii antigen system

Ii antigen system is a human blood group system based upon genes on chromosome 6.

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Immunoglobulin M

Immunoglobulin M (IgM) is one of several forms of antibody that are produced by vertebrates.

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Immunoglobulin superfamily

The immunoglobulin superfamily (IgSF) is a large protein superfamily of cell surface and soluble proteins that are involved in the recognition, binding, or adhesion processes of cells.

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Indian blood group system

The Indian blood group system (In) is a classification of blood based on the presence or absence of inherited antigens that reside within the CD44 molecule that is expressed on the surface of blood cells.

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Indigenous peoples of the Americas

The indigenous peoples of the Americas are the pre-Columbian peoples of the Americas and their descendants. Although some indigenous peoples of the Americas were traditionally hunter-gatherers—and many, especially in the Amazon basin, still are—many groups practiced aquaculture and agriculture. The impact of their agricultural endowment to the world is a testament to their time and work in reshaping and cultivating the flora indigenous to the Americas. Although some societies depended heavily on agriculture, others practiced a mix of farming, hunting and gathering. In some regions the indigenous peoples created monumental architecture, large-scale organized cities, chiefdoms, states and empires. Many parts of the Americas are still populated by indigenous peoples; some countries have sizable populations, especially Belize, Bolivia, Canada, Chile, Ecuador, Greenland, Guatemala, Guyana, Mexico, Panama and Peru. At least a thousand different indigenous languages are spoken in the Americas. Some, such as the Quechuan languages, Aymara, Guaraní, Mayan languages and Nahuatl, count their speakers in millions. Many also maintain aspects of indigenous cultural practices to varying degrees, including religion, social organization and subsistence practices. Like most cultures, over time, cultures specific to many indigenous peoples have evolved to incorporate traditional aspects but also cater to modern needs. Some indigenous peoples still live in relative isolation from Western culture, and a few are still counted as uncontacted peoples.

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International Society of Blood Transfusion

The International Society of Blood Transfusion (ISBT) is a scientific society, founded in 1935, which aims to promote the study of blood transfusion, and to spread the know-how about the manner in which blood transfusion medicine and science best can serve the patient's interests.

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Kell antigen system

The Kell antigen system (also known as Kell–Cellano system) is a group of antigens on the human red blood cell surface which are important determinants of blood type and are targets for autoimmune or alloimmune diseases which destroy red blood cells.

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Kidd antigen system

The Kidd antigen system (also known as Jk antigen) is present on the membranes of red blood cells and the kidney and helps determine a person's blood type.

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Lewis antigen system

The Lewis antigen system is a human blood group system based upon genes on chromosome 19 p13.3 (FUT3 or Lewis gene) and 19q13.3, (FUT2 or secretor gene).

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Locus (genetics)

A locus (plural loci) in genetics is a fixed position on a chromosome, like the position of a gene or a marker (genetic marker).

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Lutheran antigen system

The Lutheran antigen system is a classification of human blood based on the presence of substances called Lutheran antigens on the surfaces of red blood cells.

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Malaria

Malaria is a mosquito-borne infectious disease affecting humans and other animals caused by parasitic protozoans (a group of single-celled microorganisms) belonging to the Plasmodium type.

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MNS antigen system

The MNS antigen system is a human blood group system based upon two genes (glycophorin A and glycophorin B) on chromosome 4.

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N-Acetylgalactosamine

N-Acetylgalactosamine (GalNAc), is an amino sugar derivative of galactose.

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National Center for Biotechnology Information

The National Center for Biotechnology Information (NCBI) is part of the United States National Library of Medicine (NLM), a branch of the National Institutes of Health (NIH).

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National Institutes of Health

The National Institutes of Health (NIH) is the primary agency of the United States government responsible for biomedical and public health research, founded in the late 1870s.

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Oligosaccharide

An oligosaccharide (from the Greek ὀλίγος olígos, "a few", and σάκχαρ sácchar, "sugar") is a saccharide polymer containing a small number (typically three to ten) of monosaccharides (simple sugars).

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P antigen system

P antigen system is a human blood group system based upon the A4GALT and B3GALNT1 genes on chromosome 22.

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Plasmodium knowlesi

Plasmodium knowlesi is a primate malaria parasite commonly found in Southeast Asia.

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Plasmodium vivax

Plasmodium vivax is a protozoal parasite and a human pathogen.

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Platelet

Platelets, also called thrombocytes (from Greek θρόμβος, "clot" and κύτος, "cell"), are a component of blood whose function (along with the coagulation factors) is to react to bleeding from blood vessel injury by clumping, thereby initiating a blood clot.

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Polysaccharide

Polysaccharides are polymeric carbohydrate molecules composed of long chains of monosaccharide units bound together by glycosidic linkages, and on hydrolysis give the constituent monosaccharides or oligosaccharides.

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Porphyrin

Porphyrins (/phɔɹfɚɪn/ ''POUR-fer-in'') are a group of heterocyclic macrocycle organic compounds, composed of four modified pyrrole subunits interconnected at their α carbon atoms via methine bridges (.

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Red blood cell

Red blood cells-- also known as RBCs, red cells, red blood corpuscles, haematids, erythroid cells or erythrocytes (from Greek erythros for "red" and kytos for "hollow vessel", with -cyte translated as "cell" in modern usage), are the most common type of blood cell and the vertebrate's principal means of delivering oxygen (O2) to the body tissues—via blood flow through the circulatory system.

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Rh blood group system

The Rh blood group system is one of thirty-five known human blood group systems.

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RHAG

Rh-associated glycoprotein (RHAG) is an ammonia transporter protein that in humans is encoded by the RHAG gene.

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SEMA7A

Semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) (SEMA7A) also known as CD108 (Cluster of Differentiation 108), is a human gene.

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Sequence homology

Sequence homology is the biological homology between DNA, RNA, or protein sequences, defined in terms of shared ancestry in the evolutionary history of life.

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White blood cell

White blood cells (WBCs), also called leukocytes or leucocytes, are the cells of the immune system that are involved in protecting the body against both infectious disease and foreign invaders.

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X chromosome

The X chromosome is one of the two sex-determining chromosomes (allosomes) in many organisms, including mammals (the other is the Y chromosome), and is found in both males and females.

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Xg antigen system

The XG antigen is a red blood cell surface antigen discovered in 1962.

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XK (protein)

XK (also known as Kell blood group precursor) is a protein found on human red blood cells and other tissues which is responsible for the Kx antigen which helps determine a person's blood type.

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Yt antigen system

The Yt antigen system (also known as Cartwright) is present on the membrane of red blood cells and helps determine a person's blood type.

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Blood group antigen proteins, Blood group antigens, Blood group system, Blood groups, Human Blood groups, Human blood group, Human blood group antigens, List of human blood group antigens, List of human blood group systems, Rare blood types.

References

[1] https://en.wikipedia.org/wiki/Human_blood_group_systems

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