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Metronomic therapy

Index Metronomic therapy

Metronomic therapy is a new type of chemotherapy in which anti-cancer drugs are administered in a lower dose than the maximum tolerated dose repetitively over a long period to treat cancers with fewer side effects. [1]

Table of Contents

  1. 52 relations: Abiraterone acetate, American Association for Cancer Research, Angiogenesis, Antigen presentation, Apoptosis, Biomarker, Bone marrow, Breast cancer, Cancer immunology, Cellular senescence, Chemotherapy, Circulating endothelial cell, Comorbidity, Cyclophosphamide, Cytotoxic T cell, Cytotoxicity, Dendritic cell, Docetaxel, Douglas Hanahan, Endothelial progenitor cell, Enzalutamide, Epithelium, Estrogen deprivation therapy, Etoposide, Fluoropyrimidine, Gastrointestinal tract, Immune response, Innate immune system, Lung cancer, Lymphocyte, Methotrexate, Natural killer cell, Neoplasm, Neutropenia, Non-small-cell lung cancer, Ovarian cancer, Paclitaxel, Perfusion MRI, Phases of clinical research, Platinum-based antineoplastic, Prostate cancer, Regulatory T cell, T helper cell, Targeted therapy, Thrombospondin 1, Tumor microenvironment, Tumor-associated endothelial cell, Vaccine, VEGF receptor, Vinblastine, ... Expand index (2 more) »

  2. Chemotherapy regimens

Abiraterone acetate

Abiraterone acetate, sold under the brand name Zytiga among others, is a medication used to treat prostate cancer.

See Metronomic therapy and Abiraterone acetate

American Association for Cancer Research

The American Association for Cancer Research (AACR) is the world's oldest and largest professional association related to cancer research.

See Metronomic therapy and American Association for Cancer Research

Angiogenesis

Angiogenesis is the physiological process through which new blood vessels form from pre-existing vessels, formed in the earlier stage of vasculogenesis.

See Metronomic therapy and Angiogenesis

Antigen presentation

Antigen presentation is a vital immune process that is essential for T cell immune response triggering.

See Metronomic therapy and Antigen presentation

Apoptosis

Apoptosis (from falling off) is a form of programmed cell death that occurs in multicellular organisms and in some eukaryotic, single-celled microorganisms such as yeast.

See Metronomic therapy and Apoptosis

Biomarker

In biomedical contexts, a biomarker, or biological marker, is a measurable indicator of some biological state or condition.

See Metronomic therapy and Biomarker

Bone marrow

Bone marrow is a semi-solid tissue found within the spongy (also known as cancellous) portions of bones.

See Metronomic therapy and Bone marrow

Breast cancer

Breast cancer is a cancer that develops from breast tissue.

See Metronomic therapy and Breast cancer

Cancer immunology

Cancer immunology (immuno-oncology) is an interdisciplinary branch of biology and a sub-discipline of immunology that is concerned with understanding the role of the immune system in the progression and development of cancer; the most well known application is cancer immunotherapy, which utilises the immune system as a treatment for cancer.

See Metronomic therapy and Cancer immunology

Cellular senescence

Cellular senescence is a phenomenon characterized by the cessation of cell division.

See Metronomic therapy and Cellular senescence

Chemotherapy

Chemotherapy (often abbreviated chemo, sometimes CTX and CTx) is the type of cancer treatment that uses one or more anti-cancer drugs (chemotherapeutic agents or alkylating agents) in a standard regimen.

See Metronomic therapy and Chemotherapy

Circulating endothelial cell

Circulating endothelial cells (CECs) are endothelial cells that have been shed from the lining of the vascular wall into the blood stream.

See Metronomic therapy and Circulating endothelial cell

Comorbidity

In medicine, comorbidity refers to the simultaneous presence of two or more medical conditions in a patient; often co-occurring (that is, concomitant or concurrent) with a primary condition.

See Metronomic therapy and Comorbidity

Cyclophosphamide

Cyclophosphamide (CP), also known as cytophosphane among other names, is a medication used as chemotherapy and to suppress the immune system.

See Metronomic therapy and Cyclophosphamide

Cytotoxic T cell

A cytotoxic T cell (also known as TC, cytotoxic T lymphocyte, CTL, T-killer cell, cytolytic T cell, CD8+ T-cell or killer T cell) is a T lymphocyte (a type of white blood cell) that kills cancer cells, cells that are infected by intracellular pathogens (such as viruses or bacteria), or cells that are damaged in other ways.

See Metronomic therapy and Cytotoxic T cell

Cytotoxicity

Cytotoxicity is the quality of being toxic to cells.

See Metronomic therapy and Cytotoxicity

Dendritic cell

A dendritic cell (DC) is an antigen-presenting cell (also known as an accessory cell) of the mammalian immune system.

See Metronomic therapy and Dendritic cell

Docetaxel

Docetaxel (DTX or DXL), sold under the brand name Taxotere among others, is a chemotherapy medication used to treat a number of types of cancer.

See Metronomic therapy and Docetaxel

Douglas Hanahan

Douglas Hanahan (born 1951) is an American biologist, professor and director emeritus of the Swiss Institute for Experimental Cancer Research at EPFL (École polytechnique Fédérale de Lausanne) in Lausanne, Switzerland.

See Metronomic therapy and Douglas Hanahan

Endothelial progenitor cell

Endothelial progenitor cell (or EPC) is a term that has been applied to multiple different cell types that play roles in the regeneration of the endothelial lining of blood vessels.

See Metronomic therapy and Endothelial progenitor cell

Enzalutamide

Enzalutamide, sold under the brand name Xtandi, is a nonsteroidal antiandrogen (NSAA) medication which is used in the treatment of prostate cancer.

See Metronomic therapy and Enzalutamide

Epithelium

Epithelium or epithelial tissue is a thin, continuous, protective layer of compactly packed cells with little extracellular matrix.

See Metronomic therapy and Epithelium

Estrogen deprivation therapy

Estrogen deprivation therapy, also known as endocrine therapy, is a form of hormone therapy that is used in the treatment of breast cancer.

See Metronomic therapy and Estrogen deprivation therapy

Etoposide

Etoposide, sold under the brand name Vepesid among others, is a chemotherapy medication used for the treatments of a number of types of cancer including testicular cancer, lung cancer, lymphoma, leukemia, neuroblastoma, and ovarian cancer.

See Metronomic therapy and Etoposide

Fluoropyrimidine

Fluoropyrimidines are a general class organic compounds in which the substituent(s) around a pyrimidine ring include at least one fluorine atom.

See Metronomic therapy and Fluoropyrimidine

Gastrointestinal tract

The gastrointestinal tract (GI tract, digestive tract, alimentary canal) is the tract or passageway of the digestive system that leads from the mouth to the anus. The GI tract contains all the major organs of the digestive system, in humans and other animals, including the esophagus, stomach, and intestines.

See Metronomic therapy and Gastrointestinal tract

Immune response

An immune response is a physiological reaction which occurs within an organism in the context of inflammation for the purpose of defending against exogenous factors.

See Metronomic therapy and Immune response

Innate immune system

The innate immune system or nonspecific immune system is one of the two main immunity strategies (the other being the adaptive immune system) in vertebrates.

See Metronomic therapy and Innate immune system

Lung cancer

Lung cancer, also known as lung carcinoma, is a malignant tumor that begins in the lung.

See Metronomic therapy and Lung cancer

Lymphocyte

A lymphocyte is a type of white blood cell (leukocyte) in the immune system of most vertebrates.

See Metronomic therapy and Lymphocyte

Methotrexate

Methotrexate, formerly known as amethopterin, is a chemotherapy agent and immune-system suppressant.

See Metronomic therapy and Methotrexate

Natural killer cell

Natural killer cells, also known as NK cells or large granular lymphocytes (LGL), are a type of cytotoxic lymphocyte critical to the innate immune system.

See Metronomic therapy and Natural killer cell

Neoplasm

A neoplasm is a type of abnormal and excessive growth of tissue.

See Metronomic therapy and Neoplasm

Neutropenia

Neutropenia is an abnormally low concentration of neutrophils (a type of white blood cell) in the blood.

See Metronomic therapy and Neutropenia

Non-small-cell lung cancer

Non-small-cell lung cancer (NSCLC), or non-small-cell lung carcinoma, is any type of epithelial lung cancer other than small-cell lung cancer (SCLC).

See Metronomic therapy and Non-small-cell lung cancer

Ovarian cancer

Ovarian cancer is a cancerous tumor of an ovary.

See Metronomic therapy and Ovarian cancer

Paclitaxel

Paclitaxel, sold under the brand name Taxol among others, is a chemotherapy medication used to treat ovarian cancer, esophageal cancer, breast cancer, lung cancer, Kaposi's sarcoma, cervical cancer, and pancreatic cancer.

See Metronomic therapy and Paclitaxel

Perfusion MRI

Perfusion MRI or perfusion-weighted imaging (PWI) is perfusion scanning by the use of a particular MRI sequence.

See Metronomic therapy and Perfusion MRI

Phases of clinical research

The phases of clinical research are the stages in which scientists conduct experiments with a health intervention to obtain sufficient evidence for a process considered effective as a medical treatment.

See Metronomic therapy and Phases of clinical research

Platinum-based antineoplastic

Platinum-based antineoplastic drugs (informally called platins) are chemotherapeutic agents used to treat cancer.

See Metronomic therapy and Platinum-based antineoplastic

Prostate cancer

Prostate cancer is the uncontrolled growth of cells in the prostate, a gland in the male reproductive system below the bladder.

See Metronomic therapy and Prostate cancer

Regulatory T cell

The regulatory T cells (Tregs or Treg cells), formerly known as suppressor T cells, are a subpopulation of T cells that modulate the immune system, maintain tolerance to self-antigens, and prevent autoimmune disease.

See Metronomic therapy and Regulatory T cell

T helper cell

The T helper cells (Th cells), also known as CD4+ cells or CD4-positive cells, are a type of T cell that play an important role in the adaptive immune system.

See Metronomic therapy and T helper cell

Targeted therapy

Targeted therapy or molecularly targeted therapy is one of the major modalities of medical treatment (pharmacotherapy) for cancer, others being hormonal therapy and cytotoxic chemotherapy.

See Metronomic therapy and Targeted therapy

Thrombospondin 1

Thrombospondin 1, abbreviated as THBS1, is a protein that in humans is encoded by the THBS1 gene.

See Metronomic therapy and Thrombospondin 1

Tumor microenvironment

The tumor microenvironment is a complex ecosystem surrounding a tumor, composed of cancer cells, stromal tissue (including blood vessels, immune cells, fibroblasts and signaling molecules) and the extracellular matrix.

See Metronomic therapy and Tumor microenvironment

Tumor-associated endothelial cell

Tumor-associated endothelial cells or tumor endothelial cells (TECs) refers to cells lining the tumor-associated blood vessels that control the passage of nutrients into surrounding tumor tissue.

See Metronomic therapy and Tumor-associated endothelial cell

Vaccine

A vaccine is a biological preparation that provides active acquired immunity to a particular infectious or malignant disease.

See Metronomic therapy and Vaccine

VEGF receptor

VEGF receptors (VEGFRs) are receptors for vascular endothelial growth factor (VEGF).

See Metronomic therapy and VEGF receptor

Vinblastine

Vinblastine (VBL), sold under the brand name Velban among others, is a chemotherapy medication, typically used with other medications, to treat a number of types of cancer.

See Metronomic therapy and Vinblastine

Vinorelbine

Vinorelbine (NVB), sold under the brand name Navelbine among others, is a chemotherapy medication used to treat a number of types of cancer.

See Metronomic therapy and Vinorelbine

White blood cell

White blood cells (scientific name leukocytes), also called immune cells or immunocytes, are cells of the immune system that are involved in protecting the body against both infectious disease and foreign invaders.

See Metronomic therapy and White blood cell

See also

Chemotherapy regimens

References

[1] https://en.wikipedia.org/wiki/Metronomic_therapy

Also known as Metronomic administration.

, Vinorelbine, White blood cell.