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53 relations: Anemia, Bis(cyclopentadienyl)titanium(III) chloride, Bone marrow suppression, Breast cancer, Cancer (journal), Catharanthine, Catharanthus roseus, Cell division, Centre national de la recherche scientifique, Chemotherapy, Chemotherapy-induced peripheral neuropathy, Clinical Medicine Insights: Oncology, Constipation, CRC Press, CYP3A4, Developing country, Diarrhea, Food and Drug Administration, France, Health system, Hyponatremia, Intravenous therapy, John Wiley & Sons, Journal of Medicinal Chemistry, Kidney, Laboratoires Pierre Fabre, Liver, Lung cancer, Metastatic breast cancer, Microtubule, Molecules (journal), N-Bromosuccinimide, National Health Service, Nature Reviews Cancer, Nausea, Non-small-cell lung carcinoma, Organic Letters, Phlebitis, Pregnancy, Rhabdomyosarcoma, Semisynthesis, Shortness of breath, Silver tetrafluoroborate, Springer Science+Business Media, Trifluoroacetic acid, United States, Vinblastine, Vinca alkaloid, Vincristine, Vindoline, ..., Vinorelbine, Weakness, WHO Model List of Essential Medicines. Expand index (3 more) »
Anemia
Anemia is a decrease in the total amount of red blood cells (RBCs) or hemoglobin in the blood, or a lowered ability of the blood to carry oxygen.
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Bis(cyclopentadienyl)titanium(III) chloride
Bis(cyclopentadienyl)titanium(III) chloride, also known as the Nugent–RajanBabu reagent, is the organotitanium compound which exists as a dimer with the formula 2.
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Bone marrow suppression
Bone marrow suppression also known as myelotoxicity or myelosuppression, is the decrease in production of cells responsible for providing immunity (leukocytes), carrying oxygen (erythrocytes), and/or those responsible for normal blood clotting (thrombocytes).
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Breast cancer
Breast cancer is cancer that develops from breast tissue.
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Cancer (journal)
Cancer is a biweekly peer-reviewed scientific journal covering oncology.
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Catharanthine
Catharanthine is a terpene indole alkaloid produced by the medicinal plant Catharanthus roseus.
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Catharanthus roseus
Catharanthus roseus, commonly known as the Madagascar periwinkle, rose periwinkle, or rosy periwinkle, is a species of flowering plant in the dogbane family Apocynaceae.
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Cell division
Cell division is the process by which a parent cell divides into two or more daughter cells.
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Centre national de la recherche scientifique
The French National Center for Scientific Research (Centre national de la recherche scientifique, CNRS) is the largest governmental research organisation in France and the largest fundamental science agency in Europe.
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Chemotherapy
Chemotherapy (often abbreviated to chemo and sometimes CTX or CTx) is a type of cancer treatment that uses one or more anti-cancer drugs (chemotherapeutic agents) as part of a standardized chemotherapy regimen.
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Chemotherapy-induced peripheral neuropathy
Chemotherapy-induced peripheral neuropathy (CIPN) is a progressive, enduring, and often irreversible condition featuring pain, numbness, tingling and sensitivity to cold in the hands and feet (sometimes progressing to the arms and legs) that afflicts between 30% and 40% of patients undergoing chemotherapy.
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Clinical Medicine Insights: Oncology
Clinical Medicine Insights: Oncology is a peer-reviewed open access academic journal focusing on clinical applications of oncology.
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Constipation
Constipation refers to bowel movements that are infrequent or hard to pass.
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CRC Press
The CRC Press, LLC is a publishing group based in the United States that specializes in producing technical books.
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CYP3A4
Cytochrome P450 3A4 (abbreviated CYP3A4) is an important enzyme in the body, mainly found in the liver and in the intestine.
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Developing country
A developing country (or a low and middle income country (LMIC), less developed country, less economically developed country (LEDC), underdeveloped country) is a country with a less developed industrial base and a low Human Development Index (HDI) relative to other countries.
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Diarrhea
Diarrhea, also spelled diarrhoea, is the condition of having at least three loose or liquid bowel movements each day.
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Food and Drug Administration
The Food and Drug Administration (FDA or USFDA) is a federal agency of the United States Department of Health and Human Services, one of the United States federal executive departments.
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France
France, officially the French Republic (République française), is a sovereign state whose territory consists of metropolitan France in Western Europe, as well as several overseas regions and territories.
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Health system
A health system, also sometimes referred to as health care system or as healthcare system, is the organization of people, institutions, and resources that deliver health care services to meet the health needs of target populations.
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Hyponatremia
Hyponatremia is a low sodium level in the blood.
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Intravenous therapy
Intravenous therapy (IV) is a therapy that delivers liquid substances directly into a vein (intra- + ven- + -ous).
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John Wiley & Sons
John Wiley & Sons, Inc., also referred to as Wiley, is a global publishing company that specializes in academic publishing.
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Journal of Medicinal Chemistry
The Journal of Medicinal Chemistry is a peer-reviewed medical journal covering research in medicinal chemistry.
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Kidney
The kidneys are two bean-shaped organs present in left and right sides of the body in vertebrates.
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Laboratoires Pierre Fabre
Laboratoires Pierre Fabre is a French multinational pharmaceutical and cosmetics company.
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Liver
The liver, an organ only found in vertebrates, detoxifies various metabolites, synthesizes proteins, and produces biochemicals necessary for digestion.
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Lung cancer
Lung cancer, also known as lung carcinoma, is a malignant lung tumor characterized by uncontrolled cell growth in tissues of the lung.
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Metastatic breast cancer
Metastatic breast cancer, also referred to as metastases, advanced breast cancer, secondary tumours, secondaries or stage 4 breast cancer, is a stage of breast cancer where the disease has spread to distant sites beyond the axillary lymph nodes.
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Microtubule
Microtubules are tubular polymers of tubulin that form part of the cytoskeleton that provides the cytoplasm of eukaryotic cells and some bacteria with structure and shape.
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Molecules (journal)
Molecules is a peer-reviewed open access scientific journal that focuses on all aspects of synthetic organic chemistry and natural product chemistry.
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N-Bromosuccinimide
N-Bromosuccinimide or NBS is a chemical reagent used in radical substitution, electrophilic addition, and electrophilic substitution reactions in organic chemistry.
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National Health Service
The National Health Service (NHS) is the name used for each of the public health services in the United Kingdom – the National Health Service in England, NHS Scotland, NHS Wales, and Health and Social Care in Northern Ireland – as well as a term to describe them collectively.
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Nature Reviews Cancer
Nature Reviews Cancer is a monthly review journal covering the field of oncology.
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Nausea
Nausea or queasiness is an unpleasant sense of unease, discomfort, and revulsion towards food.
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Non-small-cell lung carcinoma
Non-small-cell lung carcinoma (NSCLC) is any type of epithelial lung cancer other than small cell lung carcinoma (SCLC).
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Organic Letters
Organic Letters (usually abbreviated as Org. Lett.), is a peer-reviewed biweekly scientific journal, published since 1999 by the American Chemical Society.
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Phlebitis
Phlebitis or venitis is the inflammation of a vein, usually in the legs.
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Pregnancy
Pregnancy, also known as gestation, is the time during which one or more offspring develops inside a woman.
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Rhabdomyosarcoma
Rhabdomyosarcoma, or RMS, is an aggressive and highly malignant form of cancer that develops from skeletal (striated) muscle cells that have failed to fully differentiate.
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Semisynthesis
Semisynthesis or partial chemical synthesis is a type of chemical synthesis that uses chemical compounds isolated from natural sources (e.g., microbial cell cultures or plant material) as the starting materials to produce other novel compounds with distinct chemical and medicinal properties.
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Shortness of breath
Shortness of breath, also known as dyspnea, is the feeling that one cannot breathe well enough.
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Silver tetrafluoroborate
Silver tetrafluoroborate is an inorganic compound with the chemical formula AgBF4.
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Springer Science+Business Media
Springer Science+Business Media or Springer, part of Springer Nature since 2015, is a global publishing company that publishes books, e-books and peer-reviewed journals in science, humanities, technical and medical (STM) publishing.
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Trifluoroacetic acid
Trifluoroacetic acid (TFA) is an organofluorine compound with the chemical formula CF3CO2H.
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United States
The United States of America (USA), commonly known as the United States (U.S.) or America, is a federal republic composed of 50 states, a federal district, five major self-governing territories, and various possessions.
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Vinblastine
Vinblastine is a chemotherapy medication, typically used with other medications, to treat a number of types of cancer.
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Vinca alkaloid
Vinca alkaloids are a set of anti-mitotic and anti-microtubule alkaloid agents originally derived from the periwinkle plant Catharanthus roseus (basionym Vinca rosea) and other vinca plants.
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Vincristine
Vincristine, also known as leurocristine and marketed under the brandname Oncovin among others, is a chemotherapy medication used to treat a number of types of cancer. This includes acute lymphocytic leukemia, acute myeloid leukemia, Hodgkin's disease, neuroblastoma, and small cell lung cancer among others. It is given intravenously. Most people experience some side effects from vincristine treatment. Commonly it causes a change in sensation, hair loss, constipation, difficulty walking, and headaches. Serious side effects may include neuropathic pain, lung damage, or low blood white cells. It will likely cause harm to the baby if given during pregnancy. It works by stopping cells from dividing properly. Vincristine was first isolated in 1961. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. The wholesale cost in the developing world is between 1.80 and 42.60 USD per dose. It is a vinca alkaloid that can be obtained from the Madagascar periwinkle Catharanthus roseus.
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Vindoline
Vindoline is a chemical precursor to vinblastine.
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Vinorelbine
Vinorelbine (NVB), sold under the brand name Navelbine among others, is a chemotherapy medication used to treat a number of types of cancer.
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Weakness
Weakness or asthenia is a symptom of a number of different conditions.
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WHO Model List of Essential Medicines
The WHO Model List of Essential Medicines (EML), published by the World Health Organization (WHO), contains the medications considered to be most effective and safe to meet the most important needs in a health system.
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Redirects here:
ATC code L01CA04, ATCvet code QL01CA04, Anhydrovinblastine, C45H54N4O8, Navelbine, Navelbine Base, Vinorelbine tartrate.
References
[1] https://en.wikipedia.org/wiki/Vinorelbine
