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PSMD7

Index PSMD7

26S proteasome non-ATPase regulatory subunit 7, also known as 26S proteasome non-ATPase subunit Rpn8, is an enzyme that in humans is encoded by the PSMD7 gene. [1]

Table of Contents

  1. 60 relations: ABL (gene), Adenomatous polyposis coli, Adenosine triphosphate, ALS, Alzheimer's disease, Androgen receptor, Apoptosis, ATPase, Autoimmune disease, Cell adhesion molecule, Cell cycle, Cell growth, Creutzfeldt–Jakob disease, Cyclin-dependent kinase, Cytokine, Dementia, Enzyme, Eukaryote, Frontotemporal dementia, Gene, Heart failure, Huntington's disease, ICAM-1, Interleukin 8, Ischemia, Lupus, Lysosome, Malignancy, MHC class I, MOS (gene), Muscular dystrophy, MYB (gene), Myc, NF-κB, Nitric oxide, Oncogene, P-selectin, P53, Parkinson's disease, Prostaglandin, Protease, Proteasome, Protein c-Fos, Proteolysis, Proto-oncogene tyrosine-protein kinase Src, PSMD1, PSMD2, PSMD4, RAF kinase, Retinoblastoma, ... Expand index (10 more) »

ABL (gene)

Tyrosine-protein kinase ABL1 also known as ABL1 is a protein that, in humans, is encoded by the ABL1 gene (previous symbol ABL) located on chromosome 9.

See PSMD7 and ABL (gene)

Adenomatous polyposis coli

Adenomatous polyposis coli (APC) also known as deleted in polyposis 2.5 (DP2.5) is a protein that in humans is encoded by the APC gene.

See PSMD7 and Adenomatous polyposis coli

Adenosine triphosphate

Adenosine triphosphate (ATP) is a nucleotide that provides energy to drive and support many processes in living cells, such as muscle contraction, nerve impulse propagation, and chemical synthesis.

See PSMD7 and Adenosine triphosphate

ALS

Amyotrophic lateral sclerosis (ALS), also known as motor neurone disease (MND) or Lou Gehrig's disease in the United States, is a rare, terminal neurodegenerative disorder that results in the progressive loss of both upper and lower motor neurons that normally control voluntary muscle contraction.

See PSMD7 and ALS

Alzheimer's disease

Alzheimer's disease (AD) is a neurodegenerative disease that usually starts slowly and progressively worsens, and is the cause of 60–70% of cases of dementia.

See PSMD7 and Alzheimer's disease

Androgen receptor

The androgen receptor (AR), also known as NR3C4 (nuclear receptor subfamily 3, group C, member 4), is a type of nuclear receptor that is activated by binding any of the androgenic hormones, including testosterone and dihydrotestosterone, in the cytoplasm and then translocating into the nucleus.

See PSMD7 and Androgen receptor

Apoptosis

Apoptosis (from falling off) is a form of programmed cell death that occurs in multicellular organisms and in some eukaryotic, single-celled microorganisms such as yeast.

See PSMD7 and Apoptosis

ATPase

ATPases (Adenosine 5'-TriPhosphatase, adenylpyrophosphatase, ATP monophosphatase, triphosphatase, SV40 T-antigen, ATP hydrolase, complex V (mitochondrial electron transport), (Ca2+ + Mg2+)-ATPase, HCO3−-ATPase, adenosine triphosphatase) are a class of enzymes that catalyze the decomposition of ATP into ADP and a free phosphate ion or the inverse reaction.

See PSMD7 and ATPase

Autoimmune disease

An autoimmune disease is a condition that results from an anomalous response of the adaptive immune system, wherein it mistakenly targets and attacks healthy, functioning parts of the body as if they were foreign organisms.

See PSMD7 and Autoimmune disease

Cell adhesion molecule

Cell adhesion molecules (CAMs) are a subset of cell surface proteins that are involved in the binding of cells with other cells or with the extracellular matrix (ECM), in a process called cell adhesion.

See PSMD7 and Cell adhesion molecule

Cell cycle

The cell cycle, or cell-division cycle, is the sequential series of events that take place in a cell that causes it to divide into two daughter cells.

See PSMD7 and Cell cycle

Cell growth

Cell growth refers to an increase in the total mass of a cell, including both cytoplasmic, nuclear and organelle volume.

See PSMD7 and Cell growth

Creutzfeldt–Jakob disease

Creutzfeldt–Jakob disease (CJD), also known as subacute spongiform encephalopathy or neurocognitive disorder due to prion disease, is a fatal neurodegenerative disease.

See PSMD7 and Creutzfeldt–Jakob disease

Cyclin-dependent kinase

Cyclin-dependent kinases (CDKs) are a predominant group of serine/threonine protein kinases involved in the regulation of the cell cycle and its progression, ensuring the integrity and functionality of cellular machinery.

See PSMD7 and Cyclin-dependent kinase

Cytokine

Cytokines are a broad and loose category of small proteins (~5–25 kDa) important in cell signaling.

See PSMD7 and Cytokine

Dementia

Dementia is a syndrome associated with many neurodegenerative diseases, characterized by a general decline in cognitive abilities that affects a person's ability to perform everyday activities.

See PSMD7 and Dementia

Enzyme

Enzymes are proteins that act as biological catalysts by accelerating chemical reactions.

See PSMD7 and Enzyme

Eukaryote

The eukaryotes constitute the domain of Eukarya or Eukaryota, organisms whose cells have a membrane-bound nucleus.

See PSMD7 and Eukaryote

Frontotemporal dementia

Frontotemporal dementia (FTD), also called frontotemporal degeneration disease or frontotemporal neurocognitive disorder, encompasses several types of dementia involving the progressive degeneration of the brain's frontal and temporal lobes.

See PSMD7 and Frontotemporal dementia

Gene

In biology, the word gene has two meanings.

See PSMD7 and Gene

Heart failure

Heart failure (HF), also known as congestive heart failure (CHF), is a syndrome caused by an impairment in the heart's ability to fill with and pump blood.

See PSMD7 and Heart failure

Huntington's disease

Huntington's disease (HD), also known as Huntington's chorea, is an incurable neurodegenerative disease that is mostly inherited.

See PSMD7 and Huntington's disease

ICAM-1

ICAM-1 (Intercellular Adhesion Molecule 1) also known as CD54 (Cluster of Differentiation 54) is a protein that in humans is encoded by the ICAM1 gene.

See PSMD7 and ICAM-1

Interleukin 8

Interleukin 8 (IL-8 or chemokine (C-X-C motif) ligand 8, CXCL8) is a chemokine produced by macrophages and other cell types such as epithelial cells, airway smooth muscle cells and endothelial cells.

See PSMD7 and Interleukin 8

Ischemia

Ischemia or ischaemia is a restriction in blood supply to any tissue, muscle group, or organ of the body, causing a shortage of oxygen that is needed for cellular metabolism (to keep tissue alive).

See PSMD7 and Ischemia

Lupus

Lupus, technically known as systemic lupus erythematosus (SLE), is an autoimmune disease in which the body's immune system mistakenly attacks healthy tissue in many parts of the body.

See PSMD7 and Lupus

Lysosome

A lysosome is a single membrane-bound organelle found in many animal cells.

See PSMD7 and Lysosome

Malignancy

Malignancy is the tendency of a medical condition to become progressively worse; the term is most familiar as a characterization of cancer.

See PSMD7 and Malignancy

MHC class I

MHC class I molecules are one of two primary classes of major histocompatibility complex (MHC) molecules (the other being MHC class II) and are found on the cell surface of all nucleated cells in the bodies of vertebrates.

See PSMD7 and MHC class I

MOS (gene)

Proto-oncogene serine/threonine-protein kinase mos is an enzyme that in humans is encoded by the MOS gene.

See PSMD7 and MOS (gene)

Muscular dystrophy

Muscular dystrophies (MD) are a genetically and clinically heterogeneous group of rare neuromuscular diseases that cause progressive weakness and breakdown of skeletal muscles over time.

See PSMD7 and Muscular dystrophy

MYB (gene)

Myb genes are part of a large gene family of transcription factors found in animals and plants.

See PSMD7 and MYB (gene)

Myc

Myc is a family of regulator genes and proto-oncogenes that code for transcription factors.

See PSMD7 and Myc

NF-κB

Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a family of transcription factor protein complexes that controls transcription of DNA, cytokine production and cell survival.

See PSMD7 and NF-κB

Nitric oxide

Nitric oxide (nitrogen oxide or nitrogen monoxide) is a colorless gas with the formula.

See PSMD7 and Nitric oxide

Oncogene

An oncogene is a gene that has the potential to cause cancer.

See PSMD7 and Oncogene

P-selectin

P-selectin is a type-1 transmembrane protein that in humans is encoded by the SELP gene.

See PSMD7 and P-selectin

P53

p53, also known as Tumor protein P53, cellular tumor antigen p53 (UniProt name), or transformation-related protein 53 (TRP53) is a regulatory protein that is often mutated in human cancers.

See PSMD7 and P53

Parkinson's disease

Parkinson's disease (PD), or simply Parkinson's, is a long-term neurodegenerative disease of mainly the central nervous system that affects both the motor and non-motor systems of the body.

See PSMD7 and Parkinson's disease

Prostaglandin

Prostaglandins (PG) are a group of physiologically active lipid compounds called eicosanoids that have diverse hormone-like effects in animals.

See PSMD7 and Prostaglandin

Protease

A protease (also called a peptidase, proteinase, or proteolytic enzyme) is an enzyme that catalyzes proteolysis, breaking down proteins into smaller polypeptides or single amino acids, and spurring the formation of new protein products.

See PSMD7 and Protease

Proteasome

Proteasomes are protein complexes which degrade ubiquitin-tagged proteins by proteolysis, a chemical reaction that breaks peptide bonds.

See PSMD7 and Proteasome

Protein c-Fos

Protein c-Fos is a proto-oncogene that is the human homolog of the retroviral oncogene v-fos.

See PSMD7 and Protein c-Fos

Proteolysis

Proteolysis is the breakdown of proteins into smaller polypeptides or amino acids.

See PSMD7 and Proteolysis

Proto-oncogene tyrosine-protein kinase Src

Proto-oncogene tyrosine-protein kinase Src, also known as proto-oncogene c-Src, or simply c-Src (cellular Src; pronounced "sarc", as it is short for sarcoma), is a non-receptor tyrosine kinase protein that in humans is encoded by the SRC gene.

See PSMD7 and Proto-oncogene tyrosine-protein kinase Src

PSMD1

26S proteasome non-ATPase regulatory subunit 1, also as known as 26S Proteasome Regulatory Subunit Rpn2 (systematic nomenclature), is a protein that in humans is encoded by the PSMD1 gene.

See PSMD7 and PSMD1

PSMD2

26S proteasome non-ATPase regulatory subunit 2, also as known as 26S Proteasome Regulatory Subunit Rpn1 (systematic nomenclature), is an enzyme that in humans is encoded by the PSMD2 gene.

See PSMD7 and PSMD2

PSMD4

26S proteasome non-ATPase regulatory subunit 4, also as known as 26S Proteasome Regulatory Subunit Rpn10 (systematic nomenclature), is an enzyme that in humans is encoded by the PSMD4 gene.

See PSMD7 and PSMD4

RAF kinase

RAF kinases are a family of three serine/threonine-specific protein kinases that are related to retroviral oncogenes.

See PSMD7 and RAF kinase

Retinoblastoma

Retinoblastoma (Rb) is a rare form of cancer that rapidly develops from the immature cells of a retina, the light-detecting tissue of the eye.

See PSMD7 and Retinoblastoma

Rheumatoid arthritis

Rheumatoid arthritis (RA) is a long-term autoimmune disorder that primarily affects joints.

See PSMD7 and Rheumatoid arthritis

Sjögren syndrome

Sjögren syndrome or Sjögren's syndrome (SjS, SS) is a long-term autoimmune disease that primarily affects the body's exocrine glands, particularly the lacrimal and salivary glands.

See PSMD7 and Sjögren syndrome

STAT3

Signal transducer and activator of transcription 3 (STAT3) is a transcription factor which in humans is encoded by the STAT3 gene.

See PSMD7 and STAT3

Transcription factor

In molecular biology, a transcription factor (TF) (or sequence-specific DNA-binding factor) is a protein that controls the rate of transcription of genetic information from DNA to messenger RNA, by binding to a specific DNA sequence.

See PSMD7 and Transcription factor

Transcription factor Jun

Transcription factor Jun is a protein that in humans is encoded by the JUN gene.

See PSMD7 and Transcription factor Jun

Tumor necrosis factor

Tumor necrosis factor (TNF, cachexin, or cachectin; formerly known as tumor necrosis factor alpha, TNFα or TNF-α) is a cytokine and member of the TNF superfamily, which consists of various transmembrane proteins with a homologous TNF domain.

See PSMD7 and Tumor necrosis factor

Ubiquitin

Ubiquitin is a small (8.6 kDa) regulatory protein found in most tissues of eukaryotic organisms, i.e., it is found ''ubiquitously''.

See PSMD7 and Ubiquitin

VCAM-1

Vascular cell adhesion protein 1 also known as vascular cell adhesion molecule 1 (VCAM-1) or cluster of differentiation 106 (CD106) is a protein that in humans is encoded by the VCAM1 gene.

See PSMD7 and VCAM-1

Ventricular hypertrophy

Ventricular hypertrophy (VH) is thickening of the walls of a ventricle (lower chamber) of the heart.

See PSMD7 and Ventricular hypertrophy

Von Hippel–Lindau tumor suppressor

The Von Hippel–Lindau tumor suppressor also known as pVHL is a protein that, in humans, is encoded by the VHL gene.

See PSMD7 and Von Hippel–Lindau tumor suppressor

References

[1] https://en.wikipedia.org/wiki/PSMD7

Also known as PSMD7 (gene).

, Rheumatoid arthritis, Sjögren syndrome, STAT3, Transcription factor, Transcription factor Jun, Tumor necrosis factor, Ubiquitin, VCAM-1, Ventricular hypertrophy, Von Hippel–Lindau tumor suppressor.