30 relations: Afimoxifene, Agonist, Antigonadotropin, Breast cancer, Cardiovascular disease, Clinical trial, DNA adduct, Endoxifen, Estrogen, Estrogen receptor, Follicle-stimulating hormone, Germany, International nonproprietary name, Japan, Ligand (biochemistry), Liver, Liver tumor, Luteinizing hormone, Menopause, Nonsteroidal, Oral administration, Osteoporosis, Phases of clinical research, Selective estrogen receptor modulator, Sex hormone-binding globulin, Structural analog, Tamoxifen, Triphenylethylene, United States Adopted Name, Uterus.
Afimoxifene, also known as 4-hydroxytamoxifen (4-OHT, 4-HT, OHTAM, others), is a selective estrogen receptor modulator (SERM) of the triphenylethylene group and the major active metabolite of tamoxifen.
An agonist is a chemical that binds to a receptor and activates the receptor to produce a biological response.
An antigonadotropin is a drug which suppresses the activity and/or downstream effects of one or both of the gonadotropins, follicle-stimulating hormone (FSH) and luteinizing hormone (LH).
Breast cancer is cancer that develops from breast tissue.
Cardiovascular disease (CVD) is a class of diseases that involve the heart or blood vessels.
Christmas is an annual festival commemorating the birth of Jesus Christ,Martindale, Cyril Charles.
The Christmas season, also called the festive season, or the holiday season (mainly in the U.S. and Canada; often simply called the holidays),, is an annually recurring period recognized in many Western and Western-influenced countries that is generally considered to run from late November to early January.
Christmas Eve is the evening or entire day before Christmas Day, the festival commemorating the birth of Jesus.
Christmas traditions vary from country to country.
Clinical trials are experiments or observations done in clinical research.
In molecular genetics, a DNA adduct is a segment of DNA bound to a cancer-causing chemical.
Endoxifen, also known as N-desmethyl-4-hydroxytamoxifen, is an orally active nonsteroidal selective estrogen receptor modulator (SERM) of the triphenylethylene group that is or was under development for the treatment of estrogen receptor-positive breast cancer.
Estrogen, or oestrogen, is the primary female sex hormone.
Estrogen receptors (ERs) are a group of proteins found inside cells.
Follicle-stimulating hormone (FSH) is a gonadotropin, a glycoprotein polypeptide hormone.
Germany (Deutschland), officially the Federal Republic of Germany (Bundesrepublik Deutschland), is a sovereign state in central-western Europe.
The International Nonproprietary Name (INN) is an official generic and non-proprietary name given to a pharmaceutical drug or an active ingredient.
Japan (日本; Nippon or Nihon; formally 日本国 or Nihon-koku, lit. "State of Japan") is a sovereign island country in East Asia.
In biochemistry and pharmacology, a ligand is a substance that forms a complex with a biomolecule to serve a biological purpose.
The liver, an organ only found in vertebrates, detoxifies various metabolites, synthesizes proteins, and produces biochemicals necessary for digestion.
Liver tumors or hepatic tumors are tumors or growths on or in the liver (medical terms pertaining to the liver often start in hepato- or hepatic from the Greek word for liver, hepar).
Luteinizing hormone (LH, also known as lutropin and sometimes lutrophin) is a hormone produced by gonadotropic cells in the anterior pituitary gland.
Menopause, also known as the climacteric, is the time in most women's lives when menstrual periods stop permanently, and they are no longer able to bear children.
New Year is the time or day at which a new calendar year begins and the calendar's year count increments by one.
New Year's Day, also called simply New Year's or New Year, is observed on January 1, the first day of the year on the modern Gregorian calendar as well as the Julian calendar.
In the Gregorian calendar, New Year's Eve (also known as Old Year's Day or Saint Sylvester's Day in many countries), the last day of the year, is on 31 December which is the seventh day of Christmastide.
Nonsteroidal is a term which is used to describe a compound that is not a steroid.
Osteoporosis is a disease where increased bone weakness increases the risk of a broken bone.
The phases of clinical research are the steps in which scientists do experiments with a health intervention in an attempt to find enough evidence for a process which would be useful as a medical treatment.
Selective estrogen receptor modulators (SERMs) are a class of drugs that act on the estrogen receptor (ER).
Sex hormone-binding globulin (SHBG) or sex steroid-binding globulin (SSBG) is a glycoprotein that binds to the two sex hormones: androgen and estrogen.
A structural analog, also known as a chemical analog or simply an analog, is a compound having a structure similar to that of another compound, but differing from it in respect to a certain component.
Tamoxifen (TMX), sold under the brand name Nolvadex among others, is a medication that is used to prevent breast cancer in women and treat breast cancer in women and men.
Triphenylethylene (TPE) is a simple aromatic hydrocarbon that possesses weak estrogenic activity.
United States Adopted Names are unique nonproprietary names assigned to pharmaceuticals marketed in the United States.
The uterus (from Latin "uterus", plural uteri) or womb is a major female hormone-responsive secondary sex organ of the reproductive system in humans and most other mammals.
2018 has been designated as the third International Year of the Reef by the International Coral Reef Initiative.
2019 (MMXIX) will be a common year starting on Tuesday of the Gregorian calendar, the 2019th year of the Common Era (CE) and Anno Domini (AD) designations, the 19th year of the 3rd millennium, the 19th year of the 21st century, and the 10th and last year of the 2010s decade.
3-Hydroxytamoxifen, 3-hydroxytamoxifen, C26H29NO2, Droloxifen, FK 435, FK-435, FK435, ICI 79,280, ICI 79280, ICI-79,280, ICI-79280, ICI79,280, ICI79280, K 060, K 21060E, K-060, K-21060E, K060, K21060E, RP 60,850, RP 60850, RP-60,850, RP-60850, RP60,850, RP60850.