Table of Contents
44 relations: Active site, Acute coronary syndrome, Animal embryonic development, Atherosclerosis, Blood vessel, Cancer, Cardiovascular disease, Catenin beta-1, Cell membrane, Chromosome 1, Coronary artery disease, Dephosphorylation, Diabetes, Embryo, Embryonic stem cell, Endothelium, Enzyme, Epithelium, Exon, Fibrosis, Gene, Genome-wide association study, Glossary of biology, Glycoprotein, Hydrolysis, Insulin resistance, Integral membrane protein, KLF2, Locus (genetics), Lumen (anatomy), Lysophosphatidic acid, Metabolic syndrome, MicroRNA, Oligomer, Phosphatase, Phosphatidate phosphatase, Phosphatidic acid, Phospholipid, Protein isoform, Statin, Substrate (biology), TCF/LEF family, Transmembrane domain, Wnt signaling pathway.
Active site
In biology and biochemistry, the active site is the region of an enzyme where substrate molecules bind and undergo a chemical reaction.
Acute coronary syndrome
Acute coronary syndrome (ACS) is a syndrome (a set of signs and symptoms) due to decreased blood flow in the coronary arteries such that part of the heart muscle is unable to function properly or dies.
See PPAP2B and Acute coronary syndrome
Animal embryonic development
In developmental biology, animal embryonic development, also known as animal embryogenesis, is the developmental stage of an animal embryo.
See PPAP2B and Animal embryonic development
Atherosclerosis
Atherosclerosis is a pattern of the disease arteriosclerosis, characterized by development of abnormalities called lesions in walls of arteries.
See PPAP2B and Atherosclerosis
Blood vessel
Blood vessels are the structures of the circulatory system that transport blood throughout the human body.
Cancer
Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body.
Cardiovascular disease
Cardiovascular disease (CVD) is any disease involving the heart or blood vessels.
See PPAP2B and Cardiovascular disease
Catenin beta-1
Catenin beta-1, also known as β-catenin (beta-catenin), is a protein that in humans is encoded by the CTNNB1 gene.
Cell membrane
The cell membrane (also known as the plasma membrane or cytoplasmic membrane, and historically referred to as the plasmalemma) is a biological membrane that separates and protects the interior of a cell from the outside environment (the extracellular space).
Chromosome 1
Chromosome 1 is the designation for the largest human chromosome.
Coronary artery disease
Coronary artery disease (CAD), also called coronary heart disease (CHD), ischemic heart disease (IHD), myocardial ischemia, or simply heart disease, involves the reduction of blood flow to the cardiac muscle due to build-up of atherosclerotic plaque in the arteries of the heart.
See PPAP2B and Coronary artery disease
Dephosphorylation
In biochemistry, dephosphorylation is the removal of a phosphate () group from an organic compound by hydrolysis.
See PPAP2B and Dephosphorylation
Diabetes
Diabetes mellitus, often known simply as diabetes, is a group of common endocrine diseases characterized by sustained high blood sugar levels.
Embryo
An embryo is the initial stage of development for a multicellular organism.
Embryonic stem cell
Embryonic stem cells (ESCs) are pluripotent stem cells derived from the inner cell mass of a blastocyst, an early-stage pre-implantation embryo.
See PPAP2B and Embryonic stem cell
Endothelium
The endothelium (endothelia) is a single layer of squamous endothelial cells that line the interior surface of blood vessels and lymphatic vessels.
Enzyme
Enzymes are proteins that act as biological catalysts by accelerating chemical reactions.
Epithelium
Epithelium or epithelial tissue is a thin, continuous, protective layer of compactly packed cells with little extracellular matrix.
Exon
An exon is any part of a gene that will form a part of the final mature RNA produced by that gene after introns have been removed by RNA splicing.
See PPAP2B and Exon
Fibrosis
Fibrosis, also known as fibrotic scarring, is a pathological wound healing in which connective tissue replaces normal parenchymal tissue to the extent that it goes unchecked, leading to considerable tissue remodelling and the formation of permanent scar tissue.
Gene
In biology, the word gene has two meanings.
See PPAP2B and Gene
Genome-wide association study
In genomics, a genome-wide association study (GWA study, or GWAS), is an observational study of a genome-wide set of genetic variants in different individuals to see if any variant is associated with a trait.
See PPAP2B and Genome-wide association study
Glossary of biology
This glossary of biology terms is a list of definitions of fundamental terms and concepts used in biology, the study of life and of living organisms.
See PPAP2B and Glossary of biology
Glycoprotein
Glycoproteins are proteins which contain oligosaccharide (sugar) chains covalently attached to amino acid side-chains.
Hydrolysis
Hydrolysis is any chemical reaction in which a molecule of water breaks one or more chemical bonds.
Insulin resistance
Insulin resistance (IR) is a pathological condition in which cells either fail to respond normally to the hormone insulin or downregulate insulin receptors in response to hyperinsulinemia.
See PPAP2B and Insulin resistance
Integral membrane protein
An integral, or intrinsic, membrane protein (IMP) is a type of membrane protein that is permanently attached to the biological membrane.
See PPAP2B and Integral membrane protein
KLF2
Krüppel-like Factor 2 (KLF2), also known as lung Krüppel-like Factor (LKLF), is a protein that in humans is encoded by the KLF2 gene on chromosome 19.
See PPAP2B and KLF2
Locus (genetics)
In genetics, a locus (loci) is a specific, fixed position on a chromosome where a particular gene or genetic marker is located.
See PPAP2B and Locus (genetics)
Lumen (anatomy)
In biology, a lumen (lumina) is the inside space of a tubular structure, such as an artery or intestine.
See PPAP2B and Lumen (anatomy)
Lysophosphatidic acid
A lysophosphatidic acid (LPA) is a phospholipid derivative that can act as a signaling molecule.
See PPAP2B and Lysophosphatidic acid
Metabolic syndrome
Metabolic syndrome is a clustering of at least three of the following five medical conditions: abdominal obesity, high blood pressure, high blood sugar, high serum triglycerides, and low serum high-density lipoprotein (HDL).
See PPAP2B and Metabolic syndrome
MicroRNA
MicroRNA (miRNA) are small, single-stranded, non-coding RNA molecules containing 21 to 23 nucleotides.
Oligomer
In chemistry and biochemistry, an oligomer is a molecule that consists of a few repeating units which could be derived, actually or conceptually, from smaller molecules, monomers.
Phosphatase
In biochemistry, a phosphatase is an enzyme that uses water to cleave a phosphoric acid monoester into a phosphate ion and an alcohol.
Phosphatidate phosphatase
The enzyme phosphatidate phosphatase (PAP, EC 3.1.3.4) is a key regulatory enzyme in lipid metabolism, catalyzing the conversion of phosphatidate to diacylglycerol: The reverse conversion is catalyzed by the enzyme diacylglycerol kinase, which replaces the hydroxyl group on diacylgylcerol with a phosphate from ATP, generating ADP in the process.
See PPAP2B and Phosphatidate phosphatase
Phosphatidic acid
Phosphatidic acids are anionic phospholipids important to cell signaling and direct activation of lipid-gated ion channels.
See PPAP2B and Phosphatidic acid
Phospholipid
Phospholipids are a class of lipids whose molecule has a hydrophilic "head" containing a phosphate group and two hydrophobic "tails" derived from fatty acids, joined by an alcohol residue (usually a glycerol molecule).
Protein isoform
A protein isoform, or "protein variant", is a member of a set of highly similar proteins that originate from a single gene or gene family and are the result of genetic differences.
See PPAP2B and Protein isoform
Statin
Statins (or HMG-CoA reductase inhibitors) are a class of medications that reduce illness and mortality in people who are at high risk of cardiovascular disease.
Substrate (biology)
In biology, a substrate is the surface on which an organism (such as a plant, fungus, or animal) lives.
See PPAP2B and Substrate (biology)
TCF/LEF family
The TCF/LEF family (T cell factor/lymphoid enhancer factor family) is a group of genes that encode transcription factors which bind to DNA through a SOX-like high mobility group domain.
Transmembrane domain
A transmembrane domain (TMD) is a membrane-spanning protein domain.
See PPAP2B and Transmembrane domain
Wnt signaling pathway
The Wnt signaling pathways are a group of signal transduction pathways which begin with proteins that pass signals into a cell through cell surface receptors.
See PPAP2B and Wnt signaling pathway
References
Also known as PPAP2B (gene).