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Aurora A kinase

Index Aurora A kinase

Aurora kinase A also known as serine/threonine-protein kinase 6 is an enzyme that in humans is encoded by the AURKA gene. [1]

50 relations: Anaphase, Aneuploidy, Aster (cell biology), AURKC, Aurora B kinase, Aurora kinase, BRCA1, C-terminus, Caenorhabditis elegans, Cell cycle, Cell growth, Centriole, Centrosome, Chromosome, Complementary DNA, Cyclin-dependent kinase 1, Cytokinesis, Drosophila, Enzyme, Epithelial–mesenchymal transition, G1 phase, G2 phase, Gene, Genome, Kinase, Kinesin, MAP kinase kinase kinase, MBD3, Metaphase, Microtubule, Mitosis, N-terminus, NME1, Oocyte, P53, Phosphorylation, Polyadenylation, Polymerization, Prometaphase, Prostate cancer, Protein–protein interaction, RNA interference, S phase, Sequence homology, Spindle apparatus, TACC1, Telophase, TPX2, UBE2N, Xenopus.

Anaphase

Anaphase (from the Greek ἀνά, "up" and φάσις, "stage"), is the stage of mitosis after the metaphase when replicated chromosomes are split and the daughter chromatids are moved to opposite poles of the cell.

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Aneuploidy

Aneuploidy is the presence of an abnormal number of chromosomes in a cell, for example a human cell having 45 or 47 chromosomes instead of the usual 46.

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Aster (cell biology)

An aster is a cellular structure shaped like a star, formed around each centrosome during mitosis in an animal cell.

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AURKC

Serine/threonine-protein kinase 13 is an enzyme that in humans is encoded by the AURKC gene.

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Aurora B kinase

Aurora B kinase is a protein that functions in the attachment of the mitotic spindle to the centromere.

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Aurora kinase

Aurora kinases are serine/threonine kinases that are essential for cell proliferation.

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BRCA1

BRCA1 and BRCA1 are a human gene and its protein product, respectively.

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C-terminus

The C-terminus (also known as the carboxyl-terminus, carboxy-terminus, C-terminal tail, C-terminal end, or COOH-terminus) is the end of an amino acid chain (protein or polypeptide), terminated by a free carboxyl group (-COOH).

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Caenorhabditis elegans

Caenorhabditis elegans is a free-living (not parasitic), transparent nematode (roundworm), about 1 mm in length, that lives in temperate soil environments.

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Cell cycle

The cell cycle or cell-division cycle is the series of events that take place in a cell leading to its division and duplication of its DNA (DNA replication) to produce two daughter cells.

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Cell growth

The term cell growth is used in the contexts of biological cell development and cell division (reproduction).

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Centriole

In cell biology a centriole is a cylindrical cellular organelle composed mainly of a protein called tubulin.

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Centrosome

In cell biology, the centrosome (Latin centrum 'center' + Greek sōma 'body') is an organelle that serves as the main microtubule organizing center (MTOC) of the animal cell as well as a regulator of cell-cycle progression.

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Chromosome

A chromosome (from Ancient Greek: χρωμόσωμα, chromosoma, chroma means colour, soma means body) is a DNA molecule with part or all of the genetic material (genome) of an organism.

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Complementary DNA

In genetics, complementary DNA (cDNA) is DNA synthesized from a single stranded RNA (e.g., messenger RNA (mRNA) or microRNA) template in a reaction catalyzed by the enzyme reverse transcriptase.

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Cyclin-dependent kinase 1

Cyclin-dependent kinase 1 also known as CDK1 or cell division cycle protein 2 homolog is a highly conserved protein that functions as a serine/threonine kinase, and is a key player in cell cycle regulation.

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Cytokinesis

Cytokinesis is the part of the cell division process during which the cytoplasm of a single eukaryotic cell divides into two daughter cells.

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Drosophila

Drosophila is a genus of flies, belonging to the family Drosophilidae, whose members are often called "small fruit flies" or (less frequently) pomace flies, vinegar flies, or wine flies, a reference to the characteristic of many species to linger around overripe or rotting fruit.

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Enzyme

Enzymes are macromolecular biological catalysts.

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Epithelial–mesenchymal transition

The epithelial–mesenchymal transition (EMT) is a process by which epithelial cells lose their cell polarity and cell-cell adhesion, and gain migratory and invasive properties to become mesenchymal stem cells; these are multipotent stromal cells that can differentiate into a variety of cell types.

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G1 phase

The g1 phase, or Gap 1 phase, is the first of four phases of the cell cycle that takes place in eukaryotic cell division.

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G2 phase

G2 phase, or Gap 2 phase, is the second subphase of Interphase in the cell cycle directly preceding mitosis.

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Gene

In biology, a gene is a sequence of DNA or RNA that codes for a molecule that has a function.

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Genome

In the fields of molecular biology and genetics, a genome is the genetic material of an organism.

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Kinase

In biochemistry, a kinase is an enzyme that catalyzes the transfer of phosphate groups from high-energy, phosphate-donating molecules to specific substrates.

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Kinesin

A kinesin is a protein belonging to a class of motor proteins found in eukaryotic cells.

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MAP kinase kinase kinase

MAP kinase kinase kinase (or MAP3K or MEKK) is a serine/threonine-specific protein kinase which acts upon MAP kinase kinase.

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MBD3

Methyl-CpG-binding domain protein 3 is a protein that in humans is encoded by the MBD3 gene.

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Metaphase

Metaphase (from the Greek μετά, "adjacent" and φάσις, "stage") is a stage of mitosis in the eukaryotic cell cycle in which chromosomes are at their second-most condensed and coiled stage (they are at their most condensed in anaphase).

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Microtubule

Microtubules are tubular polymers of tubulin that form part of the cytoskeleton that provides the cytoplasm of eukaryotic cells and some bacteria with structure and shape.

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Mitosis

In cell biology, mitosis is a part of the cell cycle when replicated chromosomes are separated into two new nuclei.

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N-terminus

The N-terminus (also known as the amino-terminus, NH2-terminus, N-terminal end or amine-terminus) is the start of a protein or polypeptide referring to the free amine group (-NH2) located at the end of a polypeptide.

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NME1

Nucleoside diphosphate kinase A is an enzyme that in humans is encoded by the NME1 gene.

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Oocyte

An oocyte, oöcyte, ovocyte, or rarely ocyte, is a female gametocyte or germ cell involved in reproduction.

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P53

Tumor protein p53, also known as p53, cellular tumor antigen p53 (UniProt name), phosphoprotein p53, tumor suppressor p53, antigen NY-CO-13, or transformation-related protein 53 (TRP53), is any isoform of a protein encoded by homologous genes in various organisms, such as TP53 (humans) and Trp53 (mice).

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Phosphorylation

In chemistry, phosphorylation of a molecule is the attachment of a phosphoryl group.

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Polyadenylation

Polyadenylation is the addition of a poly(A) tail to a messenger RNA.

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Polymerization

In polymer chemistry, polymerization is a process of reacting monomer molecules together in a chemical reaction to form polymer chains or three-dimensional networks.

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Prometaphase

Prometaphase is the phase of mitosis following prophase and preceding metaphase, in eukaryotic somatic cells.

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Prostate cancer

Prostate cancer is the development of cancer in the prostate, a gland in the male reproductive system.

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Protein–protein interaction

Protein–protein interactions (PPIs) are the physical contacts of high specificity established between two or more protein molecules as a result of biochemical events steered by electrostatic forces including the hydrophobic effect.

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RNA interference

RNA interference (RNAi) is a biological process in which RNA molecules inhibit gene expression or translation, by neutralizing targeted mRNA molecules.

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S phase

S phase (synthesis phase) is the part of the cell cycle in which DNA is replicated, occurring between G1 phase and G2 phase.

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Sequence homology

Sequence homology is the biological homology between DNA, RNA, or protein sequences, defined in terms of shared ancestry in the evolutionary history of life.

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Spindle apparatus

In cell biology, the spindle apparatus (or mitotic spindle) refers to the cytoskeletal structure of eukaryotic cells that forms during cell division to separate sister chromatids between daughter cells.

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TACC1

Transforming acidic coiled-coil-containing protein 1 is a protein that in humans is encoded by the TACC1 gene.

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Telophase

Telophase (from the Greek τέλος (télos), "end" and φάσις (phásis), "stage") is the final stage in both meiosis and mitosis in a eukaryotic cell.

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TPX2

Targeting protein for Xklp2 is a protein that in humans is encoded by the TPX2 gene.

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UBE2N

Ubiquitin-conjugating enzyme E2 N is a protein that in humans is encoded by the UBE2N gene.

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Xenopus

Xenopus (Gk., ξενος, xenos.

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Redirects here:

AURKA, AURKA (gene), Aurora A, Aurora a, Aurora a kinase, Aurora kinase A, STK15, Stk15, Stk6.

References

[1] https://en.wikipedia.org/wiki/Aurora_A_kinase

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