44 relations: Aldosterone, Anabolic steroid, Androgen, Androgen receptor, Animal drug, Binding selectivity, Bolasterone, Calusterone, Chemical synthesis, Chloranil, Copper(I) chloride, Corticosteroid, Derivative (chemistry), Dienone, Dimethyltrienolone, Enamine, Estradiol (medication), Estrane, Estrous cycle, Ligand (biochemistry), Liver, Methyl group, Methylmagnesium chloride, Metribolone, Nandrolone, Normethandrone, Oral administration, Organic compound, Potency (pharmacology), Progesterone (medication), Progesterone receptor, Progestin, Progestogen, Protecting group, Pyrrolidine, Stereochemistry, Steroid, Testosterone (medication), Trademark distinctiveness, Trenbolone, Trestolone, Upjohn, 17α-Alkylated anabolic steroid, 2,3-Dichloro-5,6-dicyano-1,4-benzoquinone.
Aldosterone, the main mineralocorticoid hormone, is a steroid hormone produced by the zona glomerulosa of the adrenal cortex in the adrenal gland.
Anabolic steroids, also known more properly as anabolic–androgenic steroids (AAS), are steroidal androgens that include natural androgens like testosterone as well as synthetic androgens that are structurally related and have similar effects to testosterone.
An androgen (from Greek andr-, the stem of the word meaning "man") is any natural or synthetic steroid hormone which regulates the development and maintenance of male characteristics in vertebrates by binding to androgen receptors.
The androgen receptor (AR), also known as NR3C4 (nuclear receptor subfamily 3, group C, member 4), is a type of nuclear receptor that is activated by binding any of the androgenic hormones, including testosterone and dihydrotestosterone in the cytoplasm and then translocating into the nucleus.
An animal drug (also veterinary drug) refers to a drug intended for use in the diagnosis, cure, mitigation, treatment, or prevention of disease in animals.
Binding selectivity is defined with respect to the binding of ligands to a substrate forming a complex.
Bolasterone (brand names Myagen, Methosarb; former developmental code name U-19763), also known as 7α,17α-dimethyltestosterone, is a 17α-alkylated androgen/anabolic steroid (AAS) which is used in veterinary medicine.
Calusterone (INN, USAN) (brand names Methosarb, Riedemil; former developmental code names NSC-88536, U-22550), also known as 7β,17α-dimethyltestosterone, is an orally active anabolic-androgenic steroid (AAS) that is used as an antineoplastic agent.
Chemical synthesis is a purposeful execution of chemical reactions to obtain a product, or several products.
Chloranil is a quinone with the molecular formula C6Cl4O2.
Copper(I) chloride, commonly called cuprous chloride, is the lower chloride of copper, with the formula CuCl.
Corticosteroids are a class of steroid hormones that are produced in the adrenal cortex of vertebrates, as well as the synthetic analogues of these hormones.
In chemistry, a derivative is a compound that is derived from a similar compound by a chemical reaction.
A dienone is a class of organic compounds that are formally "derived from diene compounds by conversion of a –CH2– groups into –C(.
Dimethyltrienolone (developmental code name RU-2420) is a synthetic, orally active, and extremely potent anabolic–androgenic steroid (AAS) and 17α-alkylated 19-nortestosterone (nandrolone) derivative which was never marketed for medical use.
An enamine is an unsaturated compound derived by the condensation of an aldehyde or ketone with a secondary amine.
Estradiol, also spelled oestradiol, is a medication and naturally occurring steroid hormone.
Estrane is a C18 steroid derivative, with a gonane core.
The estrous cycle or oestrus cycle (derived from Latin oestrus 'frenzy', originally from Greek οἶστρος oîstros 'gadfly') is the recurring physiological changes that are induced by reproductive hormones in most mammalian therian females.
In biochemistry and pharmacology, a ligand is a substance that forms a complex with a biomolecule to serve a biological purpose.
The liver, an organ only found in vertebrates, detoxifies various metabolites, synthesizes proteins, and produces biochemicals necessary for digestion.
A methyl group is an alkyl derived from methane, containing one carbon atom bonded to three hydrogen atoms — CH3.
Methylmagnesium chloride is an organometallic compound with the general formula CH3MgCl.
Metribolone (developmental code name R1881), also known as methyltrienolone, is a synthetic and orally active anabolic–androgenic steroid (AAS) and a 17α-alkylated nandrolone (19-nortestosterone) derivative which was never marketed for medical use but has been widely used in scientific research as a hot ligand in androgen receptor (AR) ligand binding assays (LBAs) and as a photoaffinity label for the AR.
Nandrolone, also known as 19-nortestosterone, is an androgen and anabolic steroid (AAS) which is used in the form of esters such as nandrolone decanoate (brand name Deca-Durabolin) and nandrolone phenylpropionate (brand name Durabolin).
Normethandrone, also known as methylestrenolone or methylnortestosterone and sold under the brand name Metalutin among others, is a progestin and androgen/anabolic steroid (AAS) medication which is used in combination with an estrogen in the treatment of amenorrhea and menopausal symptoms in women.
In chemistry, an organic compound is generally any chemical compound that contains carbon.
In the field of pharmacology, potency is a measure of drug activity expressed in terms of the amount required to produce an effect of given intensity.
Progesterone is a medication and naturally occurring steroid hormone.
The progesterone receptor (PR), also known as NR3C3 or nuclear receptor subfamily 3, group C, member 3, is a protein found inside cells.
A progestin is a type of medication which is used most commonly in hormonal birth control and menopausal hormone therapy.
Progestogens, also sometimes spelled progestagens or gestagens, are a class of steroid hormones that bind to and activate the progesterone receptor (PR).
A protecting group or protective group is introduced into a molecule by chemical modification of a functional group to obtain chemoselectivity in a subsequent chemical reaction.
Pyrrolidine, also known as tetrahydropyrrole, is an organic compound with the molecular formula (CH2)4NH.
Stereochemistry, a subdiscipline of chemistry, involves the study of the relative spatial arrangement of atoms that form the structure of molecules and their manipulation.
A steroid is a biologically active organic compound with four rings arranged in a specific molecular configuration.
Testosterone is a medication and naturally occurring steroid hormone.
Trademark distinctiveness is an important concept in the law governing trademarks and service marks.
Trenbolone is an androgen and anabolic steroid (AAS) of the nandrolone group which itself was never marketed.
Trestolone, also known as 7α-methyl-19-nortestosterone (MENT), is an experimental androgen/anabolic steroid (AAS) and progestogen medication which has been under development for potential use as a form of hormonal birth control for men and in androgen replacement therapy for low testosterone levels in men but has never been marketed for medical use.
The Upjohn Company was a pharmaceutical manufacturing firm founded in 1886 in Kalamazoo, Michigan by Dr. William E. Upjohn, an 1875 graduate of the University of Michigan medical school.
A 17α-alkylated anabolic steroid is a synthetic anabolic–androgenic steroid (AAS) that features an alkyl group, specifically a methyl or ethyl group, at the C17α position.
2,3-Dichloro-5,6-dicyano-1,4-benzoquinone (or DDQ) is the chemical reagent with formula C6Cl2(CN)2O2.