45 relations: Agonist, Aldosterone, Anabolic steroid, Anabolism, Androgen, Androgen receptor, Animal testing, Aromatase, Bioassay, Derivative (chemistry), Estradiol (medication), Estrane, Estrogen (medication), Gynecomastia, Hepatotoxicity, Ligand (biochemistry), Liver, Medicine, Metabolism, Methyl group, Methyltestosterone, Metribolone, Mibolerone, Nandrolone, Normethandrone, Oral administration, Organic compound, Potency (pharmacology), Progesterone (medication), Progesterone receptor, Progestogen, Prostate, Receptor (biochemistry), Side effect, Skin, Steroid, Structural analog, Substrate (chemistry), Testosterone (medication), Tissue (biology), Trenbolone, Trestolone, Trimethyltrienolone, 17α-Alkylated anabolic steroid, 5α-Reductase.
An agonist is a chemical that binds to a receptor and activates the receptor to produce a biological response.
Aldosterone, the main mineralocorticoid hormone, is a steroid hormone produced by the zona glomerulosa of the adrenal cortex in the adrenal gland.
Anabolic steroids, also known more properly as anabolic–androgenic steroids (AAS), are steroidal androgens that include natural androgens like testosterone as well as synthetic androgens that are structurally related and have similar effects to testosterone.
Anabolism (from ἁνά, "upward" and βάλλειν, "to throw") is the set of metabolic pathways that construct molecules from smaller units.
An androgen (from Greek andr-, the stem of the word meaning "man") is any natural or synthetic steroid hormone which regulates the development and maintenance of male characteristics in vertebrates by binding to androgen receptors.
The androgen receptor (AR), also known as NR3C4 (nuclear receptor subfamily 3, group C, member 4), is a type of nuclear receptor that is activated by binding any of the androgenic hormones, including testosterone and dihydrotestosterone in the cytoplasm and then translocating into the nucleus.
Animal testing, also known as animal experimentation, animal research and in vivo testing, is the use of non-human animals in experiments that seek to control the variables that affect the behavior or biological system under study.
Aromatase, also called estrogen synthetase or estrogen synthase, is an enzyme responsible for a key step in the biosynthesis of estrogens.
A bioassay is an analytical method to determine concentration or potency of a substance by its effect on living cells or tissues.
In chemistry, a derivative is a compound that is derived from a similar compound by a chemical reaction.
Estradiol, also spelled oestradiol, is a medication and naturally occurring steroid hormone.
Estrane is a C18 steroid derivative, with a gonane core.
An estrogen is a type of medication which is used most commonly in hormonal birth control and menopausal hormone therapy.
Gynecomastia is an endocrine system disorder in which a noncancerous increase in the size of male breast tissue occurs.
Hepatotoxicity (from hepatic toxicity) implies chemical-driven liver damage.
In biochemistry and pharmacology, a ligand is a substance that forms a complex with a biomolecule to serve a biological purpose.
The liver, an organ only found in vertebrates, detoxifies various metabolites, synthesizes proteins, and produces biochemicals necessary for digestion.
Medicine is the science and practice of the diagnosis, treatment, and prevention of disease.
Metabolism (from μεταβολή metabolē, "change") is the set of life-sustaining chemical transformations within the cells of organisms.
A methyl group is an alkyl derived from methane, containing one carbon atom bonded to three hydrogen atoms — CH3.
Methyltestosterone, sold under the brand names Android, Metandren, and Testred among others, is an androgen and anabolic steroid (AAS) medication which is used in the treatment of low testosterone levels in men, delayed puberty in boys, at low doses as a component of menopausal hormone therapy for menopausal symptoms like hot flashes, osteoporosis, and low sexual desire in women, and to treat breast cancer in women.
Metribolone (developmental code name R1881), also known as methyltrienolone, is a synthetic and orally active anabolic–androgenic steroid (AAS) and a 17α-alkylated nandrolone (19-nortestosterone) derivative which was never marketed for medical use but has been widely used in scientific research as a hot ligand in androgen receptor (AR) ligand binding assays (LBAs) and as a photoaffinity label for the AR.
Mibolerone, also known as dimethylnortestosterone (DMNT) and sold under the brand names Cheque Drops and Matenon, is a synthetic, orally active, and extremely potent anabolic–androgenic steroid (AAS) and a 17α-alkylated nandrolone (19-nortestosterone) derivative which was marketed by Upjohn for use as a veterinary drug.
Nandrolone, also known as 19-nortestosterone, is an androgen and anabolic steroid (AAS) which is used in the form of esters such as nandrolone decanoate (brand name Deca-Durabolin) and nandrolone phenylpropionate (brand name Durabolin).
Normethandrone, also known as methylestrenolone or methylnortestosterone and sold under the brand name Metalutin among others, is a progestin and androgen/anabolic steroid (AAS) medication which is used in combination with an estrogen in the treatment of amenorrhea and menopausal symptoms in women.
In chemistry, an organic compound is generally any chemical compound that contains carbon.
In the field of pharmacology, potency is a measure of drug activity expressed in terms of the amount required to produce an effect of given intensity.
Progesterone is a medication and naturally occurring steroid hormone.
The progesterone receptor (PR), also known as NR3C3 or nuclear receptor subfamily 3, group C, member 3, is a protein found inside cells.
Progestogens, also sometimes spelled progestagens or gestagens, are a class of steroid hormones that bind to and activate the progesterone receptor (PR).
The prostate (from Ancient Greek προστάτης, prostates, literally "one who stands before", "protector", "guardian") is a compound tubuloalveolar exocrine gland of the male reproductive system in most mammals.
In biochemistry and pharmacology, a receptor is a protein molecule that receives chemical signals from outside a cell.
In medicine, a side effect is an effect, whether therapeutic or adverse, that is secondary to the one intended; although the term is predominantly employed to describe adverse effects, it can also apply to beneficial, but unintended, consequences of the use of a drug.
Skin is the soft outer tissue covering vertebrates.
A steroid is a biologically active organic compound with four rings arranged in a specific molecular configuration.
A structural analog, also known as a chemical analog or simply an analog, is a compound having a structure similar to that of another compound, but differing from it in respect to a certain component.
In chemistry, a substrate is typically the chemical species being observed in a chemical reaction, which reacts with a reagent to generate a product.
Testosterone is a medication and naturally occurring steroid hormone.
In biology, tissue is a cellular organizational level between cells and a complete organ.
Trenbolone is an androgen and anabolic steroid (AAS) of the nandrolone group which itself was never marketed.
Trestolone, also known as 7α-methyl-19-nortestosterone (MENT), is an experimental androgen/anabolic steroid (AAS) and progestogen medication which has been under development for potential use as a form of hormonal birth control for men and in androgen replacement therapy for low testosterone levels in men but has never been marketed for medical use.
Trimethyltrienolone (TMT), also known by its developmental code name R-2956 or RU-2956, is an antiandrogen medication which was never introduced for medical use but has been used in scientific research.
A 17α-alkylated anabolic steroid is a synthetic anabolic–androgenic steroid (AAS) that features an alkyl group, specifically a methyl or ethyl group, at the C17α position.
5α-reductases, also known as 3-oxo-5α-steroid 4-dehydrogenases, are enzymes involved in steroid metabolism.
7α,17α-Dimethyltrenbolone, 7α,17α-Dimethyltrienolone, 7α,17α-dimethyltrenbolone, 7α,17α-dimethyltrienolone, 7α-Methylmetribolone, 7α-methylmetribolone, Dimethyltrenbolone, Dimethyltrienbolone, Dimetribolone, Methylmetribolone, R 2420, R-2420, R2420, RU 2420, RU-2420, RU2420.