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67 relations: Amino acid, Aneuploidy, Base (chemistry), Bipolar disorder, Birth defect, C-terminus, Calmodulin, Cardiomyopathy, CDK5RAP2, Cell cycle, Cell cycle checkpoint, Cell nucleus, Centriole, Centrosome, CHD3, CHD4, Chromosome, Chronic myelogenous leukemia, Coiled coil, Complementary DNA, CPM (gene), Cytoplasm, Cytoskeleton, Diabetes mellitus, Diabetes mellitus type 2, DISC1, Disease, Down syndrome, Dyslipidemia, G2-M DNA damage checkpoint, Gene, Homology (biology), Immunity (medical), Inflammation, Insulin, Insulin resistance, Interphase, Intrauterine growth restriction, Metaphase, Microcephalic osteodysplastic primordial dwarfism type II, Microtubule, Mitosis, N-terminus, Neuron, Nuclear export signal, Nuclear localization sequence, PCM1, Pericentriolar material, Phosphorylation, PLK1, ..., Primordial dwarfism, Progeroid syndromes, Protein, Protein complex, Protein domain, Protein kinase A, Protein kinase C, Protein superfamily, Protein–protein interaction, Residue (chemistry), Seckel syndrome, Separase, Sister chromatids, Skeletal muscle, Spindle apparatus, Subcellular localization, Tubulin. Expand index (17 more) »
Amino acid
Amino acids are organic compounds containing amine (-NH2) and carboxyl (-COOH) functional groups, along with a side chain (R group) specific to each amino acid.
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Aneuploidy
Aneuploidy is the presence of an abnormal number of chromosomes in a cell, for example a human cell having 45 or 47 chromosomes instead of the usual 46.
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Base (chemistry)
In chemistry, bases are substances that, in aqueous solution, release hydroxide (OH−) ions, are slippery to the touch, can taste bitter if an alkali, change the color of indicators (e.g., turn red litmus paper blue), react with acids to form salts, promote certain chemical reactions (base catalysis), accept protons from any proton donor, and/or contain completely or partially displaceable OH− ions.
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Bipolar disorder
Bipolar disorder, previously known as manic depression, is a mental disorder that causes periods of depression and periods of abnormally elevated mood.
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Birth defect
A birth defect, also known as a congenital disorder, is a condition present at birth regardless of its cause.
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C-terminus
The C-terminus (also known as the carboxyl-terminus, carboxy-terminus, C-terminal tail, C-terminal end, or COOH-terminus) is the end of an amino acid chain (protein or polypeptide), terminated by a free carboxyl group (-COOH).
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Calmodulin
Calmodulin (CaM) (an abbreviation for calcium-modulated protein) is a multifunctional intermediate calcium-binding messenger protein expressed in all eukaryotic cells.
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Cardiomyopathy
Cardiomyopathy is a group of diseases that affect the heart muscle.
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CDK5RAP2
CDK5 regulatory subunit-associated protein 2 is a protein that in humans is encoded by the CDK5RAP2 gene.
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Cell cycle
The cell cycle or cell-division cycle is the series of events that take place in a cell leading to its division and duplication of its DNA (DNA replication) to produce two daughter cells.
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Cell cycle checkpoint
Cell cycle checkpoints are control mechanisms in eukaryotic cells which ensure proper division of the cell.
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Cell nucleus
In cell biology, the nucleus (pl. nuclei; from Latin nucleus or nuculeus, meaning kernel or seed) is a membrane-enclosed organelle found in eukaryotic cells.
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Centriole
In cell biology a centriole is a cylindrical cellular organelle composed mainly of a protein called tubulin.
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Centrosome
In cell biology, the centrosome (Latin centrum 'center' + Greek sōma 'body') is an organelle that serves as the main microtubule organizing center (MTOC) of the animal cell as well as a regulator of cell-cycle progression.
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CHD3
Chromodomain-helicase-DNA-binding protein 3 is an enzyme that in humans is encoded by the CHD3 gene.
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CHD4
Chromodomain-helicase-DNA-binding protein 4 is an enzyme that in humans is encoded by the CHD4 gene.
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Chromosome
A chromosome (from Ancient Greek: χρωμόσωμα, chromosoma, chroma means colour, soma means body) is a DNA molecule with part or all of the genetic material (genome) of an organism.
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Chronic myelogenous leukemia
Chronic myelogenous leukemia (CML), also known as chronic myeloid leukemia, is a cancer of the white blood cells.
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Coiled coil
A coiled coil is a structural motif in proteins in which 2–7 alpha-helices are coiled together like the strands of a rope (dimers and trimers are the most common types).
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Complementary DNA
In genetics, complementary DNA (cDNA) is DNA synthesized from a single stranded RNA (e.g., messenger RNA (mRNA) or microRNA) template in a reaction catalyzed by the enzyme reverse transcriptase.
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CPM (gene)
Carboxypeptidase M is an enzyme that in humans is encoded by the CPM gene.
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Cytoplasm
In cell biology, the cytoplasm is the material within a living cell, excluding the cell nucleus.
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Cytoskeleton
A cytoskeleton is present in all cells of all domains of life (archaea, bacteria, eukaryotes).
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Diabetes mellitus
Diabetes mellitus (DM), commonly referred to as diabetes, is a group of metabolic disorders in which there are high blood sugar levels over a prolonged period.
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Diabetes mellitus type 2
Diabetes mellitus type 2 (also known as type 2 diabetes) is a long-term metabolic disorder that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.
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DISC1
Disrupted in schizophrenia 1 is a protein that in humans is encoded by the DISC1 gene.
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Disease
A disease is any condition which results in the disorder of a structure or function in an organism that is not due to any external injury.
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Down syndrome
Down syndrome (DS or DNS), also known as trisomy 21, is a genetic disorder caused by the presence of all or part of a third copy of chromosome 21.
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Dyslipidemia
Dyslipidemia is an abnormal amount of lipids (e.g. triglycerides, cholesterol and/or fat phospholipids) in the blood.
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G2-M DNA damage checkpoint
The G2-M DNA damage checkpoint is an important cell cycle checkpoint in eukaryotic organisms ranging from yeast to mammals.
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Gene
In biology, a gene is a sequence of DNA or RNA that codes for a molecule that has a function.
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Homology (biology)
In biology, homology is the existence of shared ancestry between a pair of structures, or genes, in different taxa.
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Immunity (medical)
In biology, immunity is the balanced state of multicellular organisms having adequate biological defenses to fight infection, disease, or other unwanted biological invasion, while having adequate tolerance to avoid allergy, and autoimmune diseases.
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Inflammation
Inflammation (from inflammatio) is part of the complex biological response of body tissues to harmful stimuli, such as pathogens, damaged cells, or irritants, and is a protective response involving immune cells, blood vessels, and molecular mediators.
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Insulin
Insulin (from Latin insula, island) is a peptide hormone produced by beta cells of the pancreatic islets; it is considered to be the main anabolic hormone of the body.
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Insulin resistance
Insulin resistance (IR) is a pathological condition in which cells fail to respond normally to the hormone insulin.
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Interphase
Interphase is the phase of the cell cycle in which a typical cell spends most of its life.
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Intrauterine growth restriction
Intrauterine growth restriction (IUGR) refers to poor growth of a fetus while in the mother's womb during pregnancy.
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Metaphase
Metaphase (from the Greek μετά, "adjacent" and φάσις, "stage") is a stage of mitosis in the eukaryotic cell cycle in which chromosomes are at their second-most condensed and coiled stage (they are at their most condensed in anaphase).
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Microcephalic osteodysplastic primordial dwarfism type II
Microcephalic osteodysplastic primordial dwarfism type II (MOPD II) is listed as a "rare disease" by the Office of Rare Diseases (ORD) of the National Institutes of Health (NIH).
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Microtubule
Microtubules are tubular polymers of tubulin that form part of the cytoskeleton that provides the cytoplasm of eukaryotic cells and some bacteria with structure and shape.
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Mitosis
In cell biology, mitosis is a part of the cell cycle when replicated chromosomes are separated into two new nuclei.
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N-terminus
The N-terminus (also known as the amino-terminus, NH2-terminus, N-terminal end or amine-terminus) is the start of a protein or polypeptide referring to the free amine group (-NH2) located at the end of a polypeptide.
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Neuron
A neuron, also known as a neurone (British spelling) and nerve cell, is an electrically excitable cell that receives, processes, and transmits information through electrical and chemical signals.
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Nuclear export signal
A nuclear export signal (NES) is a short amino acid sequence of 4 hydrophobic residues in a protein that targets it for export from the cell nucleus to the cytoplasm through the nuclear pore complex using nuclear transport.
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Nuclear localization sequence
A nuclear localization signal or sequence (NLS) is an amino acid sequence that 'tags' a protein for import into the cell nucleus by nuclear transport.
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PCM1
Pericentriolar material 1, also known as PCM1, is a protein which in humans is encoded by the PCM1 gene.
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Pericentriolar material
Pericentriolar material (PCM, sometimes also called pericentriolar matrix) is an amorphous mass of protein which makes up the part of the animal centrosome that surrounds the two centrioles.
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Phosphorylation
In chemistry, phosphorylation of a molecule is the attachment of a phosphoryl group.
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PLK1
Serine/threonine-protein kinase PLK1, also known as polo-like kinase 1 (PLK-1) or serine/threonine-protein kinase 13 (STPK13), is an enzyme that in humans is encoded by the PLK1 (polo-like kinase 1) gene.
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Primordial dwarfism
Primordial dwarfism (PD) is a form of dwarfism that results in a smaller body size in all stages of life beginning from before birth.
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Progeroid syndromes
Progeroid syndromes (PS) are a group of rare genetic disorders which mimic physiological aging, making affected individuals appear to be older than they are.
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Protein
Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.
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Protein complex
A protein complex or multiprotein complex is a group of two or more associated polypeptide chains.
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Protein domain
A protein domain is a conserved part of a given protein sequence and (tertiary) structure that can evolve, function, and exist independently of the rest of the protein chain.
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Protein kinase A
In cell biology, protein kinase A (PKANot to be confused with pKa, the symbol for the acid dissociation constant.) is a family of enzymes whose activity is dependent on cellular levels of cyclic AMP (cAMP).
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Protein kinase C
Protein kinase C, commonly abbreviated to PKC (EC 2.7.11.13), is a family of protein kinase enzymes that are involved in controlling the function of other proteins through the phosphorylation of hydroxyl groups of serine and threonine amino acid residues on these proteins, or a member of this family.
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Protein superfamily
A protein superfamily is the largest grouping (clade) of proteins for which common ancestry can be inferred (see homology).
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Protein–protein interaction
Protein–protein interactions (PPIs) are the physical contacts of high specificity established between two or more protein molecules as a result of biochemical events steered by electrostatic forces including the hydrophobic effect.
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Residue (chemistry)
In chemistry residue is whatever remains or acts as a contaminant after a given class of events.
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Seckel syndrome
The Seckel syndrome or microcephalic primordial dwarfism (also known as bird-headed dwarfism, Harper's syndrome, Virchow-Seckel dwarfism, and Bird-headed dwarf of Seckel) is an extremely rare congenital nanosomic disorder.
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Separase
Separase, also known as separin, is a cysteine protease responsible for triggering anaphase by hydrolysing cohesin, which is the protein responsible for binding sister chromatids during the early stage of anaphase.
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Sister chromatids
A sister chromatid refers to the identical copies (chromatids) formed by the replication of a chromosome, with both copies joined together by a common centromere.
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Skeletal muscle
Skeletal muscle is one of three major muscle types, the others being cardiac muscle and smooth muscle.
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Spindle apparatus
In cell biology, the spindle apparatus (or mitotic spindle) refers to the cytoskeletal structure of eukaryotic cells that forms during cell division to separate sister chromatids between daughter cells.
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Subcellular localization
The cells of eukaryotic organisms are elaborately subdivided into functionally-distinct membrane-bound compartments.
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Tubulin
Tubulin in molecular biology can refer either to the tubulin protein superfamily of globular proteins, or one of the member proteins of that superfamily.
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Redirects here:
Kendrin, PCNT (gene), Pericentrin.
References
[1] https://en.wikipedia.org/wiki/PCNT
