43 relations: Adrenal gland, Agonist, Aldosterone, Algestone, Antimineralocorticoid, Biosynthesis, Breast development, Central nervous system, Circulatory system, CYP17A1, CYP3A4, Cytochrome P450, Cytochrome P450, family 1, member A1, Endogeny (biology), Enzyme, Fetus, Hydroxylation, Ligand (biochemistry), Liver, Metabolism, Metabolite, Mineralocorticoid receptor, Molar concentration, Natriuresis, Ovary, Physiology, Placenta, Pregnancy, Progesterone, Progesterone receptor A, Progesterone receptor B, Progestogen, Receptor antagonist, Reproductive system, Spironolactone, Steroid, Steroid hormone, Testicle, Tissue (biology), 11-Deoxycorticosterone, 17α-Hydroxyprogesterone, 20α-Dihydroprogesterone, 5α-Dihydroprogesterone.
Adrenal gland
The adrenal glands (also known as suprarenal glands) are endocrine glands that produce a variety of hormones including adrenaline and the steroids aldosterone and cortisol.
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Agonist
An agonist is a chemical that binds to a receptor and activates the receptor to produce a biological response.
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Aldosterone
Aldosterone, the main mineralocorticoid hormone, is a steroid hormone produced by the zona glomerulosa of the adrenal cortex in the adrenal gland.
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Algestone
Algestone, also known as alphasone or alfasone, is a progestin which was never marketed.
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Antimineralocorticoid
An antimineralocorticoid, MCRA, or an aldosterone antagonist, is a diuretic drug which antagonizes the action of aldosterone at mineralocorticoid receptors.
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Biosynthesis
Biosynthesis (also called anabolism) is a multi-step, enzyme-catalyzed process where substrates are converted into more complex products in living organisms.
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Breast development
Breast development, also known as mammogenesis, is a complex biological process in primates that takes place throughout a female's life.
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Central nervous system
The central nervous system (CNS) is the part of the nervous system consisting of the brain and spinal cord.
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Circulatory system
The circulatory system, also called the cardiovascular system or the vascular system, is an organ system that permits blood to circulate and transport nutrients (such as amino acids and electrolytes), oxygen, carbon dioxide, hormones, and blood cells to and from the cells in the body to provide nourishment and help in fighting diseases, stabilize temperature and pH, and maintain homeostasis.
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CYP17A1
Cytochrome P450 17A1, also called steroid 17α-monooxygenase, 17α-hydroxylase, 17,20-lyase, or 17,20-desmolase, is an enzyme of the hydroxylase type that in humans is encoded by the CYP17A1 gene on chromosome 10.
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CYP3A4
Cytochrome P450 3A4 (abbreviated CYP3A4) is an important enzyme in the body, mainly found in the liver and in the intestine.
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Cytochrome P450
Cytochromes P450 (CYPs) are proteins of the superfamily containing heme as a cofactor and, therefore, are hemoproteins.
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Cytochrome P450, family 1, member A1
Cytochrome P450, family 1, subfamily A, polypeptide 1 is a protein that in humans is encoded by the CYP1A1 gene.
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Endogeny (biology)
Endogenous substances and processes are those that originate from within an organism, tissue, or cell.
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Enzyme
Enzymes are macromolecular biological catalysts.
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Fetus
A fetus is a stage in the prenatal development of viviparous organisms.
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Hydroxylation
Hydroxylation is a chemical process that introduces a hydroxyl group (-OH) into an organic compound.
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Ligand (biochemistry)
In biochemistry and pharmacology, a ligand is a substance that forms a complex with a biomolecule to serve a biological purpose.
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Liver
The liver, an organ only found in vertebrates, detoxifies various metabolites, synthesizes proteins, and produces biochemicals necessary for digestion.
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Metabolism
Metabolism (from μεταβολή metabolē, "change") is the set of life-sustaining chemical transformations within the cells of organisms.
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Metabolite
A metabolite is the intermediate end product of metabolism.
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Mineralocorticoid receptor
The mineralocorticoid receptor (or MR, MLR, MCR), also known as the aldosterone receptor or nuclear receptor subfamily 3, group C, member 2, (NR3C2) is a protein that in humans is encoded by the NR3C2 gene that is located on chromosome 4q31.1-31.2.
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Molar concentration
Molar concentration (also called molarity, amount concentration or substance concentration) is a measure of the concentration of a chemical species, in particular of a solute in a solution, in terms of amount of substance per unit volume of solution.
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Natriuresis
Natriuresis is the process of sodium excretion in the urine through the action of the kidneys.
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Ovary
The ovary is an organ found in the female reproductive system that produces an ovum.
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Physiology
Physiology is the scientific study of normal mechanisms, and their interactions, which work within a living system.
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Placenta
The placenta is an organ that connects the developing fetus to the uterine wall to allow nutrient uptake, thermo-regulation, waste elimination, and gas exchange via the mother's blood supply; to fight against internal infection; and to produce hormones which support pregnancy.
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Pregnancy
Pregnancy, also known as gestation, is the time during which one or more offspring develops inside a woman.
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Progesterone
Progesterone (P4) is an endogenous steroid and progestogen sex hormone involved in the menstrual cycle, pregnancy, and embryogenesis of humans and other species.
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Progesterone receptor A
The progesterone receptor A (PR-A) is one of three known isoforms of the progesterone receptor (PR), the main biological target of the endogenous progestogen sex hormone progesterone.
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Progesterone receptor B
The progesterone receptor B (PR-B) is one of three known isoforms of the progesterone receptor (PR), the main biological target of the endogenous progestogen sex hormone progesterone.
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Progestogen
Progestogens, also sometimes spelled progestagens or gestagens, are a class of steroid hormones that bind to and activate the progesterone receptor (PR).
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Receptor antagonist
A receptor antagonist is a type of receptor ligand or drug that blocks or dampens a biological response by binding to and blocking a receptor rather than activating it like an agonist.
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Reproductive system
The reproductive system or genital system is a system of sex organs within an organism which work together for the purpose of sexual reproduction.
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Spironolactone
Spironolactone, sold under the brand name Aldactone among others, is a medication that is primarily used to treat fluid build-up due to heart failure, liver scarring, or kidney disease.
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Steroid
A steroid is a biologically active organic compound with four rings arranged in a specific molecular configuration.
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Steroid hormone
A steroid hormone is a steroid that acts as a hormone.
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Testicle
The testicle or testis is the male reproductive gland in all animals, including humans.
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Tissue (biology)
In biology, tissue is a cellular organizational level between cells and a complete organ.
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11-Deoxycorticosterone
11-Deoxycorticosterone (DOC), or simply deoxycorticosterone, also known as 21-hydroxyprogesterone, as well as desoxycortone (INN), deoxycortone, and cortexone, is a steroid hormone produced by the adrenal gland that possesses mineralocorticoid activity and acts as a precursor to aldosterone.
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17α-Hydroxyprogesterone
17α-Hydroxyprogesterone (17α-OHP), or hydroxyprogesterone (OHP), is an endogenous progestogen steroid hormone related to progesterone.
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20α-Dihydroprogesterone
20α-Dihydroprogesterone (20α-DHP), also known as 20α-hydroxyprogesterone (20α-OHP), is a naturally occurring, endogenous progestogen.
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5α-Dihydroprogesterone
5α-Dihydroprogesterone (5α-DHP), also known as allopregnanedione, as well as 5α-pregnane-3,20-dione, is an endogenous progestogen and neurosteroid that is synthesized from progesterone.
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Redirects here:
16-Hydroxyprogesterone, 16-OH-PROG, 16-OHP, 16-OHPROG, 16-hydroxyprogesterone, 16α-OH-PROG, 16α-OHP, 16α-OHPROG, 16α-hydroxyprogesterone.
References
[1] https://en.wikipedia.org/wiki/16α-Hydroxyprogesterone