Table of Contents
61 relations: Ablation, Adenine, Albumin, Alkyl sulfonate, Alkylating antineoplastic agent, Alkylation, Antiemetic, Aplasia, Apoptosis, Benzodiazepine, Bilirubin, Bone marrow, Cachexia, Carcinogen, Chemotherapy, Chronic myelogenous leukemia, Clofarabine, Crosslinking of DNA, Cyclodextrin, Cyclophosphamide, DNA, DNA replication, Edema, Fludarabine, Food and Drug Administration, Glutathione, GSK plc, Guanine, Hematopoietic stem cell transplantation, Hepatic veno-occlusive disease, Hepatomegaly, Hyperpigmentation, Imatinib, Integral, International Agency for Research on Cancer, Intravenous therapy, Itraconazole, Leukemia, Levetiracetam, Liver, Lymphoma, Mesylate, Metabolite, Myeloproliferative neoplasm, Nausea, Nucleophile, Oral administration, Otsuka Pharmaceutical, Paracetamol, Phenytoin, ... Expand index (11 more) »
- Alkylating antineoplastic agents
- Alkylsulfonates
- Mesylate esters
- Specialty drugs
Ablation
Ablation (ablatio – removal) is the removal or destruction of something from an object by vaporization, chipping, erosive processes, or by other means.
Adenine
Adenine (symbol A or Ade) is a purine nucleobase.
Albumin
Albumin is a family of globular proteins, the most common of which are the serum albumins.
Alkyl sulfonate
Alkyl sulfonates are esters of alkane sulfonic acids with the general formula R-SO2-O-R'.
See Busulfan and Alkyl sulfonate
Alkylating antineoplastic agent
An alkylating antineoplastic agent is an alkylating agent used in cancer treatment that attaches an alkyl group (CnH2n+1) to DNA. Busulfan and alkylating antineoplastic agent are alkylating antineoplastic agents.
See Busulfan and Alkylating antineoplastic agent
Alkylation
Alkylation is a chemical reaction that entails transfer of an alkyl group.
Antiemetic
An antiemetic is a drug that is effective against vomiting and nausea.
Aplasia
Aplasia (from Greek a, "not", "no" + plasis, "formation") is a birth defect where an organ or tissue is wholly or largely absent.
Apoptosis
Apoptosis (from falling off) is a form of programmed cell death that occurs in multicellular organisms and in some eukaryotic, single-celled microorganisms such as yeast.
Benzodiazepine
Benzodiazepines (BZD, BDZ, BZs), colloquially called "benzos", are a class of depressant drugs whose core chemical structure is the fusion of a benzene ring and a diazepine ring.
See Busulfan and Benzodiazepine
Bilirubin
Bilirubin (BR) (from the Latin for "red bile") is a red-orange compound that occurs in the normal catabolic pathway that breaks down heme in vertebrates.
Bone marrow
Bone marrow is a semi-solid tissue found within the spongy (also known as cancellous) portions of bones.
Cachexia
Cachexia is a complex syndrome associated with an underlying illness, causing ongoing muscle loss that is not entirely reversed with nutritional supplementation.
Carcinogen
A carcinogen is any agent that promotes the development of cancer.
Chemotherapy
Chemotherapy (often abbreviated chemo, sometimes CTX and CTx) is the type of cancer treatment that uses one or more anti-cancer drugs (chemotherapeutic agents or alkylating agents) in a standard regimen.
Chronic myelogenous leukemia
Chronic myelogenous leukemia (CML), also known as chronic myeloid leukemia, is a cancer of the white blood cells.
See Busulfan and Chronic myelogenous leukemia
Clofarabine
Clofarabine is a purine nucleoside antimetabolite marketed in the United States and Canada as Clolar.
Crosslinking of DNA
In genetics, crosslinking of DNA occurs when various exogenous or endogenous agents react with two nucleotides of DNA, forming a covalent linkage between them.
See Busulfan and Crosslinking of DNA
Cyclodextrin
Cyclodextrins are a family of cyclic oligosaccharides, consisting of a macrocyclic ring of glucose subunits joined by α-1,4 glycosidic bonds.
Cyclophosphamide
Cyclophosphamide (CP), also known as cytophosphane among other names, is a medication used as chemotherapy and to suppress the immune system. Busulfan and Cyclophosphamide are IARC Group 1 carcinogens.
See Busulfan and Cyclophosphamide
DNA
Deoxyribonucleic acid (DNA) is a polymer composed of two polynucleotide chains that coil around each other to form a double helix.
See Busulfan and DNA
DNA replication
In molecular biology, DNA replication is the biological process of producing two identical replicas of DNA from one original DNA molecule.
See Busulfan and DNA replication
Edema
Edema (AmE), also spelled oedema (BrE), and also known as fluid retention, dropsy, hydropsy and swelling, is the build-up of fluid in the body's tissue.
Fludarabine
Fludarabine is a purine analogue and antineoplastic agent.
Food and Drug Administration
The United States Food and Drug Administration (FDA or US FDA) is a federal agency of the Department of Health and Human Services.
See Busulfan and Food and Drug Administration
Glutathione
Glutathione (GSH) is an organic compound with the chemical formula.
GSK plc
GSK plc (an acronym from its former name GlaxoSmithKline plc) is a British multinational pharmaceutical and biotechnology company with global headquarters in London.
Guanine
Guanine (symbol G or Gua) is one of the four main nucleobases found in the nucleic acids DNA and RNA, the others being adenine, cytosine, and thymine (uracil in RNA).
Hematopoietic stem cell transplantation
Hematopoietic stem-cell transplantation (HSCT) is the transplantation of multipotent hematopoietic stem cells, usually derived from bone marrow, peripheral blood, or umbilical cord blood, in order to replicate inside a patient and produce additional normal blood cells.
See Busulfan and Hematopoietic stem cell transplantation
Hepatic veno-occlusive disease
Hepatic veno-occlusive disease (VOD) or veno-occlusive disease with immunodeficiency is a potentially life-threatening condition in which some of the small veins in the liver are obstructed.
See Busulfan and Hepatic veno-occlusive disease
Hepatomegaly
Hepatomegaly is enlargement of the liver.
Hyperpigmentation
Hyperpigmentation is the darkening of an area of skin or nails caused by increased melanin.
See Busulfan and Hyperpigmentation
Imatinib
Imatinib, sold under the brand names Gleevec and Glivec (both marketed worldwide by Novartis) among others, is an oral targeted therapy medication used to treat cancer. Busulfan and Imatinib are Orphan drugs.
Integral
In mathematics, an integral is the continuous analog of a sum, which is used to calculate areas, volumes, and their generalizations.
International Agency for Research on Cancer
The International Agency for Research on Cancer (IARC; Centre International de Recherche sur le Cancer, CIRC) is an intergovernmental agency forming part of the World Health Organization of the United Nations.
See Busulfan and International Agency for Research on Cancer
Intravenous therapy
Intravenous therapy (abbreviated as IV therapy) is a medical technique that administers fluids, medications and nutrients directly into a person's vein.
See Busulfan and Intravenous therapy
Itraconazole
Itraconazole, sometimes abbreviated ITZ, is an antifungal medication used to treat a number of fungal infections. This includes aspergillosis, blastomycosis, coccidioidomycosis, histoplasmosis, and paracoccidioidomycosis. It may be given by mouth or intravenously. Common side effects include nausea, diarrhea, abdominal pain, rash, and headache. Busulfan and Itraconazole are Orphan drugs.
Leukemia
Leukemia (also spelled leukaemia; pronounced) is a group of blood cancers that usually begin in the bone marrow and produce high numbers of abnormal blood cells.
Levetiracetam
Levetiracetam, sold under the brand name Keppra among others, is a medication used to treat epilepsy.
See Busulfan and Levetiracetam
Liver
The liver is a major metabolic organ exclusively found in vertebrate animals, which performs many essential biological functions such as detoxification of the organism, and the synthesis of proteins and various other biochemicals necessary for digestion and growth.
Lymphoma
Lymphoma is a group of blood and lymph tumors that develop from lymphocytes (a type of white blood cell).
Mesylate
In organosulfur chemistry, a mesylate is any salt or ester of methanesulfonic acid.
Metabolite
In biochemistry, a metabolite is an intermediate or end product of metabolism.
Myeloproliferative neoplasm
Myeloproliferative neoplasms (MPNs) are a group of rare blood cancers in which excess red blood cells, white blood cells or platelets are produced in the bone marrow.
See Busulfan and Myeloproliferative neoplasm
Nausea
Nausea is a diffuse sensation of unease and discomfort, sometimes perceived as an urge to vomit.
Nucleophile
In chemistry, a nucleophile is a chemical species that forms bonds by donating an electron pair.
Oral administration
| name.
See Busulfan and Oral administration
Otsuka Pharmaceutical
(), abbreviated OPC, is a pharmaceutical company headquartered in Tokyo, Osaka and Naruto, Japan.
See Busulfan and Otsuka Pharmaceutical
Paracetamol
Paracetamol (acetaminophen) is a non-opioid analgesic and antipyretic agent used to treat fever and mild to moderate pain.
Phenytoin
Phenytoin (PHT), sold under the brand name Dilantin among others, is an anti-seizure medication.
Platelet
Platelets or thrombocytes are a blood component whose function (along with the coagulation factors) is to react to bleeding from blood vessel injury by clumping, thereby initiating a blood clot.
Pulmonary fibrosis
Pulmonary fibrosis is a condition in which the lungs become scarred over time.
See Busulfan and Pulmonary fibrosis
Rate equation
In chemistry, the rate equation (also known as the rate law or empirical differential rate equation) is an empirical differential mathematical expression for the reaction rate of a given reaction in terms of concentrations of chemical species and constant parameters (normally rate coefficients and partial orders of reaction) only.
See Busulfan and Rate equation
Seizure
A seizure is a period of symptoms due to abnormally excessive or synchronous neuronal activity in the brain.
Serotonin
Serotonin or 5-hydroxytryptamine (5-HT) is a monoamine neurotransmitter.
SN2 reaction
Bimolecular nucleophilic substitution (SN2) is a type of reaction mechanism that is common in organic chemistry.
Sulfonate
In organosulfur chemistry, a sulfonate is a salt, anion or ester of a sulfonic acid.
Therapeutic drug monitoring
Therapeutic drug monitoring (TDM) is a branch of clinical chemistry and clinical pharmacology that specializes in the measurement of medication levels in blood.
See Busulfan and Therapeutic drug monitoring
Thrombocytopenia
In hematology, thrombocytopenia is a condition characterized by abnormally low levels of platelets (also known as thrombocytes) in the blood.
See Busulfan and Thrombocytopenia
Ursodeoxycholic acid
Ursodeoxycholic acid (UDCA), also known as ursodiol, is a secondary bile acid, produced in humans and most other species from metabolism by intestinal bacteria. Busulfan and Ursodeoxycholic acid are Orphan drugs.
See Busulfan and Ursodeoxycholic acid
Vomiting
Vomiting (also known as emesis and throwing up) is the involuntary, forceful expulsion of the contents of one's stomach through the mouth and sometimes the nose.
See also
Alkylating antineoplastic agents
- Alkylating antineoplastic agent
- Busulfan
- Carboquone
- Carmustine
- Chlornaphazine
- Chlorozotocin
- Dibrospidium chloride
- Duocarmycin
- Evofosfamide
- Glufosfamide
- Lomustine
- Mannomustine
- Mannosulfan
- Mitobronitol
- Mitomycins
- Nimustine
- Nitrogen mustards
- Nitrosoureas
- Normustine
- Phenanthriplatin
- Pipobroman
- Ranimustine
- Semustine
- Streptozotocin
- Temozolomide
- Thiotepa
- Treosulfan
- Triaziquone
- Triethylenemelamine
- Triplatin tetranitrate
Alkylsulfonates
- Busulfan
- Mannosulfan
- Treosulfan
Mesylate esters
- Busulfan
- Ethane dimethanesulfonate
- Ethyl methanesulfonate
- Mannosulfan
- Methyl methanesulfonate
- Treosulfan
Specialty drugs
- Accredo
- Alexion Pharmaceuticals
- Allion Healthcare
- Animal efficacy rule
- Bacterial therapy
- Bausch Health
- Beacon Pharmaceuticals
- Benzer Pharmacy
- Bevacizumab
- Biopharmaceutical
- Busulfan
- CVS Health
- Capecitabine
- Delcath Systems
- Diplomat Pharmacy
- Express Scripts
- Gilead Sciences
- Interferon beta-1a
- Living medicine
- Medicago Inc.
- Melphalan
- Omnicare
- Palbociclib
- Portola Pharmaceuticals
- Rituximab
- Sodium thiosulfate
- Sofosbuvir
- Specialty drugs in the United States
- Specialty pharmacy
- Stromagen
- Trastuzumab
- Tumor-homing bacteria
- Vaxart
- Verastem Oncology
- ViiV Healthcare
- Walgreens Boots Alliance
- Zalcitabine
References
Also known as 1,4-Butanediol dimethanesulfonate, ATC code L01AB01, ATCvet code QL01AB01, Busilvex, Busulfex, Busulphan, C6H14O6S2, Citosulfan, Leucosulfan, Mablin, Mielevcin, Mielosan, Mielucin, Milecitan, Mileran, Misulban, Mitosan, Mitostan, Myeleukon, Myeloleukon, Myelosan, Mylecytan, Myleran, Myleran Tablets.