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62 relations: Advanced glycation end-product, Alternative splicing, Alzheimer's disease, Amyloid beta, Antibody, Arthritis, Atherosclerosis, Atlas of Genetics and Cytogenetics in Oncology and Haematology, Base pair, Calprotectin, CD36, Cell surface receptor, Chromatin, Dendritic cell, Diabetes mellitus, Diabetic nephropathy, Diabetic neuropathy, Diabetic retinopathy, Endogeny (biology), Enzyme, Galectin, Gene, Glycan, Glycoprotein, Heart failure, HMGB1, Inflammation, Intracellular, Ligand, Macrophage, Maillard reaction, Major histocompatibility complex, Myocardial infarction, Natural killer cell, Neoplasm, NF-κB, OLR1, Pathogenesis, Pattern recognition receptor, Peripheral artery disease, Phases of clinical research, Polymorphism (biology), Precursor mRNA, Protein domain, Protein isoform, Psoriasis, Receptor (biochemistry), Receptor antagonist, Rheumatoid arthritis, S100A12, ..., S100A15, S100A7, S100B, S100P, Scavenger receptor (immunology), Single-nucleotide polymorphism, Small molecule, Structural motif, Takayasu's arteritis, Tissue (biology), Transmembrane protein, Unified atomic mass unit. Expand index (12 more) »
Advanced glycation end-product
Advanced glycation end products (AGEs) are proteins or lipids that become glycated as a result of exposure to sugars.
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Alternative splicing
Alternative splicing, or differential splicing, is a regulated process during gene expression that results in a single gene coding for multiple proteins.
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Alzheimer's disease
Alzheimer's disease (AD), also referred to simply as Alzheimer's, is a chronic neurodegenerative disease that usually starts slowly and worsens over time.
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Amyloid beta
Amyloid beta (Aβ or Abeta) denotes peptides of 36–43 amino acids that are crucially involved in Alzheimer's disease as the main component of the amyloid plaques found in the brains of Alzheimer patients.
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Antibody
An antibody (Ab), also known as an immunoglobulin (Ig), is a large, Y-shaped protein produced mainly by plasma cells that is used by the immune system to neutralize pathogens such as pathogenic bacteria and viruses.
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Arthritis
Arthritis is a term often used to mean any disorder that affects joints.
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Atherosclerosis
Atherosclerosis is a disease in which the inside of an artery narrows due to the build up of plaque.
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Atlas of Genetics and Cytogenetics in Oncology and Haematology
The Atlas of Genetics and Cytogenetics in Oncology and Haematology, created in 1997 by Jean-Loup Huret (with bioinformatics by Philippe Dessen) is a collection of resources on genes, chromosomes anomalies, leukemias, solid tumours, and cancer-prone diseases.
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Base pair
A base pair (bp) is a unit consisting of two nucleobases bound to each other by hydrogen bonds.
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Calprotectin
Calprotectin is a complex of the mammalian proteins S100A8 and S100A9.
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CD36
CD36 (cluster of differentiation 36), also known as platelet glycoprotein 4, fatty acid translocase (FAT), scavenger receptor class B member 3 (SCARB3), and glycoproteins 88 (GP88), IIIb (GPIIIB), or IV (GPIV) is a protein that in humans is encoded by the CD36 gene.
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Cell surface receptor
Cell surface receptors (membrane receptors, transmembrane receptors) are receptors that are embedded in the membranes of cells.
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Chromatin
Chromatin is a complex of macromolecules found in cells, consisting of DNA, protein, and RNA.
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Dendritic cell
Dendritic cells (DCs) are antigen-presenting cells (also known as accessory cells) of the mammalian immune system.
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Diabetes mellitus
Diabetes mellitus (DM), commonly referred to as diabetes, is a group of metabolic disorders in which there are high blood sugar levels over a prolonged period.
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Diabetic nephropathy
Diabetic nephropathy (DN), also known as diabetic kidney disease, is the chronic loss of kidney function occurring in those with diabetes mellitus.
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Diabetic neuropathy
Diabetic neuropathies are nerve damaging disorders associated with diabetes mellitus.
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Diabetic retinopathy
Diabetic retinopathy, also known as diabetic eye disease, is a medical condition in which damage occurs to the retina due to diabetes mellitus.
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Endogeny (biology)
Endogenous substances and processes are those that originate from within an organism, tissue, or cell.
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Enzyme
Enzymes are macromolecular biological catalysts.
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Galectin
Galectins are a class of proteins that bind specifically to β-galactoside sugars, such as N-acetyllactosamine (Galβ1-3GlcNAc or Galβ1-4GlcNAc), which can be bound to proteins by either N-linked or O-linked glycosylation.
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Gene
In biology, a gene is a sequence of DNA or RNA that codes for a molecule that has a function.
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Glycan
The terms glycan and polysaccharide are defined by IUPAC as synonyms meaning "compounds consisting of a large number of monosaccharides linked glycosidically".
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Glycoprotein
Glycoproteins are proteins that contain oligosaccharide chains (glycans) covalently attached to amino acid side-chains.
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Heart failure
Heart failure (HF), often referred to as congestive heart failure (CHF), is when the heart is unable to pump sufficiently to maintain blood flow to meet the body's needs.
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HMGB1
High mobility group box 1 protein, also known as high-mobility group protein 1 (HMG-1) and amphoterin, is a protein that in humans is encoded by the HMGB1 gene.
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Inflammation
Inflammation (from inflammatio) is part of the complex biological response of body tissues to harmful stimuli, such as pathogens, damaged cells, or irritants, and is a protective response involving immune cells, blood vessels, and molecular mediators.
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Intracellular
In cell biology, molecular biology and related fields, the word intracellular means "inside the cell".
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Ligand
In coordination chemistry, a ligand is an ion or molecule (functional group) that binds to a central metal atom to form a coordination complex.
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Macrophage
Macrophages (big eaters, from Greek μακρός (makrós).
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Maillard reaction
The Maillard reaction is a chemical reaction between amino acids and reducing sugars that gives browned food its distinctive flavor.
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Major histocompatibility complex
The major histocompatibility complex (MHC) is a set of cell surface proteins essential for the acquired immune system to recognize foreign molecules in vertebrates, which in turn determines histocompatibility.
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Myocardial infarction
Myocardial infarction (MI), commonly known as a heart attack, occurs when blood flow decreases or stops to a part of the heart, causing damage to the heart muscle.
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Natural killer cell
Natural killer cells or NK cells are a type of cytotoxic lymphocyte critical to the innate immune system.
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Neoplasm
Neoplasia is a type of abnormal and excessive growth of tissue.
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NF-κB
NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) is a protein complex that controls transcription of DNA, cytokine production and cell survival.
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OLR1
Oxidized low-density lipoprotein receptor 1 (Ox-LDL receptor 1) also known as lectin-type oxidized LDL receptor 1 (LOX-1) is a protein that in humans is encoded by the OLR1 gene.
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Pathogenesis
The pathogenesis of a disease is the biological mechanism (or mechanisms) that leads to the diseased state.
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Pattern recognition receptor
Pattern recognition receptors (PRRs) play a crucial role in the proper function of the innate immune system.
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Peripheral artery disease
Peripheral artery disease (PAD) is a narrowing of the arteries other than those that supply the heart or the brain.
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Phases of clinical research
The phases of clinical research are the steps in which scientists do experiments with a health intervention in an attempt to find enough evidence for a process which would be useful as a medical treatment.
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Polymorphism (biology)
Polymorphism in biology and zoology is the occurrence of two or more clearly different morphs or forms, also referred to as alternative phenotypes, in the population of a species.
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Precursor mRNA
Precursor mRNA (pre-mRNA) is an immature single strand of messenger ribonucleic acid (mRNA).
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Protein domain
A protein domain is a conserved part of a given protein sequence and (tertiary) structure that can evolve, function, and exist independently of the rest of the protein chain.
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Protein isoform
A protein isoform, or "protein variant" is a member of a set of highly similar proteins that originate from a single gene or gene family and are the result of genetic differences.
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Psoriasis
Psoriasis is a long-lasting autoimmune disease characterized by patches of abnormal skin.
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Receptor (biochemistry)
In biochemistry and pharmacology, a receptor is a protein molecule that receives chemical signals from outside a cell.
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Receptor antagonist
A receptor antagonist is a type of receptor ligand or drug that blocks or dampens a biological response by binding to and blocking a receptor rather than activating it like an agonist.
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Rheumatoid arthritis
Rheumatoid arthritis (RA) is a long-term autoimmune disorder that primarily affects joints.
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S100A12
S100 calcium-binding protein A12 (S100A12) is a protein that in humans is encoded by the S100A12 gene.
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S100A15
S100 calcium-binding protein A15 (S100A15), also known as koebnerisin and S100 calcium-binding protein A7A (S100A7A), is a protein that in humans is encoded by the S100A7A (alias:S100A15) gene.
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S100A7
S100 calcium-binding protein A7 (S100A7), also known as psoriasin, is a protein that in humans is encoded by the S100A7 gene.
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S100B
S100 calcium-binding protein B (S100B) is a protein of the S-100 protein family.
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S100P
S100 calcium-binding protein P (S100P) is a protein that in humans is encoded by the S100P gene.
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Scavenger receptor (immunology)
Scavenger receptors are receptors on macrophages and other cells that bind to numerous ligands, such as bacterial cell-wall components, and remove them from the blood.
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Single-nucleotide polymorphism
A single-nucleotide polymorphism, often abbreviated to SNP (plural), is a variation in a single nucleotide that occurs at a specific position in the genome, where each variation is present to some appreciable degree within a population (e.g. > 1%).
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Small molecule
Within the fields of molecular biology and pharmacology, a small molecule is a low molecular weight (< 900 daltons) organic compound that may regulate a biological process, with a size on the order of 1 nm.
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Structural motif
In a chain-like biological molecule, such as a protein or nucleic acid, a structural motif is a supersecondary structure, which also appears in a variety of other molecules.
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Takayasu's arteritis
Takayasu's arteritis (also known as Takayasu's disease, "aortic arch syndrome," "nonspecific aortoarteritis," and "pulseless disease") is a form of large vessel granulomatous vasculitisAmerican College of Physicians (ACP).
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Tissue (biology)
In biology, tissue is a cellular organizational level between cells and a complete organ.
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Transmembrane protein
A transmembrane protein (TP) is a type of integral membrane protein that spans the entirety of the biological membrane to which it is permanently attached.
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Unified atomic mass unit
The unified atomic mass unit or dalton (symbol: u, or Da) is a standard unit of mass that quantifies mass on an atomic or molecular scale (atomic mass).
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Redirects here:
AGER, AGER (gene), Advanced glycosylation end product-specific receptor, Azeliragon, RAGE receptor.
References
[1] https://en.wikipedia.org/wiki/RAGE_(receptor)
