39 relations: Aldosterone, Anabolic steroid, Androgen, Androgen receptor, Androstanolone, Antiandrogen, Antiestrogen, Antimineralocorticoid, Benorterone, Binding selectivity, BOMT, Cyproterone, Cyproterone acetate, Derivative (chemistry), Dihydrotestosterone, Estradiol (medication), Estrane, Estrogen (medication), Flutamide, France, In vitro, Intrinsic activity, Ligand (biochemistry), Metribolone, Nandrolone, Nilutamide, Nonsteroidal antiandrogen, Organic compound, Partial agonist, Potency (pharmacology), Progesterone (medication), Progestogen, Receptor antagonist, Roussel Uclaf, Scientific method, Steroid, Steroidal antiandrogen, Testosterone (medication), Trenbolone.
Aldosterone, the main mineralocorticoid hormone, is a steroid hormone produced by the zona glomerulosa of the adrenal cortex in the adrenal gland.
Anabolic steroids, also known more properly as anabolic–androgenic steroids (AAS), are steroidal androgens that include natural androgens like testosterone as well as synthetic androgens that are structurally related and have similar effects to testosterone.
An androgen (from Greek andr-, the stem of the word meaning "man") is any natural or synthetic steroid hormone which regulates the development and maintenance of male characteristics in vertebrates by binding to androgen receptors.
The androgen receptor (AR), also known as NR3C4 (nuclear receptor subfamily 3, group C, member 4), is a type of nuclear receptor that is activated by binding any of the androgenic hormones, including testosterone and dihydrotestosterone in the cytoplasm and then translocating into the nucleus.
Androstanolone, or stanolone, also known as dihydrotestosterone (DHT) and sold under the brand name Andractim among others, is an androgen and anabolic steroid (AAS) medication and hormone which is used mainly in the treatment of low testosterone levels in men.
Antiandrogens, also known as androgen antagonists or testosterone blockers, are a class of drugs that prevent androgens like testosterone and dihydrotestosterone (DHT) from mediating their biological effects in the body.
Antiestrogens, also known as estrogen antagonists or estrogen blockers, are a class of drugs which prevent estrogens like estradiol from mediating their biological effects in the body.
An antimineralocorticoid, MCRA, or an aldosterone antagonist, is a diuretic drug which antagonizes the action of aldosterone at mineralocorticoid receptors.
Benorterone, also known by its developmental code name SKF-7690 and as 17α-methyl-B-nortestosterone, is an steroidal antiandrogen which was studied for potential medical use but was never marketed.
Binding selectivity is defined with respect to the binding of ligands to a substrate forming a complex.
BOMT, also known by its developmental code name Ro 7-2340 and as 6α-bromo-4-oxa-17α-methyl-5α-dihydrotestosterone, is a synthetic steroidal antiandrogen which was first developed in 1970 and was never marketed for medical use.
Christmas is an annual festival commemorating the birth of Jesus Christ,Martindale, Cyril Charles.
The Christmas season, also called the festive season, or the holiday season (mainly in the U.S. and Canada; often simply called the holidays),, is an annually recurring period recognized in many Western and Western-influenced countries that is generally considered to run from late November to early January.
Christmas Eve is the evening or entire day before Christmas Day, the festival commemorating the birth of Jesus.
Christmas traditions vary from country to country.
Cyproterone, also known by its developmental code name SH-80881, is a steroidal antiandrogen which was studied in the 1960s and 1970s but was never introduced for medical use.
Cyproterone acetate (CPA), sold alone under the brand name Androcur or with ethinylestradiol (EE) under the brand names Diane or Diane-35 among others, is an antiandrogen and progestogen which is used in the treatment of androgen-dependent conditions like acne, excessive hair growth, early puberty, and prostate cancer, as a component of feminizing hormone therapy for transgender women, and in birth control pills.
In chemistry, a derivative is a compound that is derived from a similar compound by a chemical reaction.
Dihydrotestosterone (DHT), or 5α-dihydrotestosterone (5α-DHT), also known as androstanolone or stanolone, is an endogenous androgen sex steroid and hormone.
Estradiol, also spelled oestradiol, is a medication and naturally occurring steroid hormone.
Estrane is a C18 steroid derivative, with a gonane core.
An estrogen is a type of medication which is used most commonly in hormonal birth control and menopausal hormone therapy.
Flutamide, sold under the brand name Eulexin among others, is a nonsteroidal antiandrogen (NSAA) which is used primarily to treat prostate cancer.
France, officially the French Republic (République française), is a sovereign state whose territory consists of metropolitan France in Western Europe, as well as several overseas regions and territories.
In vitro (meaning: in the glass) studies are performed with microorganisms, cells, or biological molecules outside their normal biological context.
Intrinsic activity (IA) or efficacy refers to the relative ability of a drug-receptor complex to produce a maximum functional response.
In biochemistry and pharmacology, a ligand is a substance that forms a complex with a biomolecule to serve a biological purpose.
Metribolone (developmental code name R1881), also known as methyltrienolone, is a synthetic and orally active anabolic–androgenic steroid (AAS) and a 17α-alkylated nandrolone (19-nortestosterone) derivative which was never marketed for medical use but has been widely used in scientific research as a hot ligand in androgen receptor (AR) ligand binding assays (LBAs) and as a photoaffinity label for the AR.
Nandrolone, also known as 19-nortestosterone, is an androgen and anabolic steroid (AAS) which is used in the form of esters such as nandrolone decanoate (brand name Deca-Durabolin) and nandrolone phenylpropionate (brand name Durabolin).
New Year is the time or day at which a new calendar year begins and the calendar's year count increments by one.
New Year's Day, also called simply New Year's or New Year, is observed on January 1, the first day of the year on the modern Gregorian calendar as well as the Julian calendar.
In the Gregorian calendar, New Year's Eve (also known as Old Year's Day or Saint Sylvester's Day in many countries), the last day of the year, is on 31 December which is the seventh day of Christmastide.
Nilutamide, sold under the brand names Nilandron and Anandron, is a nonsteroidal antiandrogen (NSAA) which is used in the treatment of prostate cancer.
A nonsteroidal antiandrogen (NSAA) is an antiandrogen with a nonsteroidal chemical structure.
In chemistry, an organic compound is generally any chemical compound that contains carbon.
In pharmacology, partial agonists are drugs that bind to and activate a given receptor, but have only partial efficacy at the receptor relative to a full agonist.
In the field of pharmacology, potency is a measure of drug activity expressed in terms of the amount required to produce an effect of given intensity.
Progesterone is a medication and naturally occurring steroid hormone.
Progestogens, also sometimes spelled progestagens or gestagens, are a class of steroid hormones that bind to and activate the progesterone receptor (PR).
A receptor antagonist is a type of receptor ligand or drug that blocks or dampens a biological response by binding to and blocking a receptor rather than activating it like an agonist.
Roussel Uclaf S.A. was a French pharmaceutical company and one of several predecessor companies of today's Sanofi.
Scientific method is an empirical method of knowledge acquisition, which has characterized the development of natural science since at least the 17th century, involving careful observation, which includes rigorous skepticism about what one observes, given that cognitive assumptions about how the world works influence how one interprets a percept; formulating hypotheses, via induction, based on such observations; experimental testing and measurement of deductions drawn from the hypotheses; and refinement (or elimination) of the hypotheses based on the experimental findings.
A steroid is a biologically active organic compound with four rings arranged in a specific molecular configuration.
A steroidal antiandrogen (SAA) is an antiandrogen with a steroidal chemical structure.
Testosterone is a medication and naturally occurring steroid hormone.
Trenbolone is an androgen and anabolic steroid (AAS) of the nandrolone group which itself was never marketed.
2018 has been designated as the third International Year of the Reef by the International Coral Reef Initiative.
2019 (MMXIX) will be a common year starting on Tuesday of the Gregorian calendar, the 2019th year of the Common Era (CE) and Anno Domini (AD) designations, the 19th year of the 3rd millennium, the 19th year of the 21st century, and the 10th and last year of the 2010s decade.
2,2,17-Trimethyltrenbolone, 2,2,17-Trimethyltrienolone, 2,2,17-trimethyltrenbolone, 2,2,17-trimethyltrienolone, 2,2-Dimethylmethyltrenbolone, 2,2-Dimethylmethyltrienolone, 2,2-Dimethylmetrenbolone, 2,2-Dimethylmetribolone, 2,2-Dimethylmetrienolone, 2,2-dimethylmethyltrenbolone, 2,2-dimethylmethyltrienolone, 2,2-dimethylmetrenbolone, 2,2-dimethylmetribolone, 2,2-dimethylmetrienolone, 2α,2β,17α-Trimethyltrenbolone, 2α,2β,17α-Trimethyltrienolone, 2α,2β,17α-trimethyltrenbolone, 2α,2β,17α-trimethyltrienolone, 2α,2β,Dimethylmethyltrenbolone, 2α,2β,Dimethylmethyltrienolone, 2α,2β,Dimethylmetrenbolone, 2α,2β,Dimethylmetribolone, 2α,2β,dimethylmethyltrenbolone, 2α,2β,dimethylmethyltrienolone, 2α,2β,dimethylmetrenbolone, 2α,2β,dimethylmetribolone, 2α,2β-Dimethylmethyltrenbolone, 2α,2β-Dimethylmethyltrienolone, 2α,2β-Dimethylmetribolone, 2α,2β-dimethylmethyltrenbolone, 2α,2β-dimethylmethyltrienolone, 2α,2β-dimethylmetribolone, R 2956, R-2956, R2956, RU 2956, RU-2956, RU2956, Trimethyltrenbolone.