51 relations: Agonist, Allylestrenol, Allyltestosterone, Anabolic steroid, Anabolism, Androgen, Androgen receptor, Bioassay, Derivative (chemistry), EC50, Estrane, Estrous cycle, Ethyl group, Ethynyl, Europe, Filly, Horse, In vitro, Mare, Methyl group, Metribolone, Nandrolone, Norethisterone, Noretynodrel, Norgestrel, Norgestrienone, Offspring, Oral administration, Organic compound, Pharmaceutical industry, Pig, Pregnancy, Progesterone, Progesterone receptor, Progestin, Progestogen, Roussel Uclaf, Stallion, Steroid, Structural analog, Structure–activity relationship, Testosterone, Testosterone (medication), Trademark distinctiveness, Trenbolone, United States, Veterinary medicine, Virilization, Yeast, 17α-Alkylated anabolic steroid, ..., 17α-Allyl-19-nortestosterone. Expand index (1 more) » « Shrink index
An agonist is a chemical that binds to a receptor and activates the receptor to produce a biological response.
Allylestrenol, sold under the brand names Gestanin and Turinal among others, is a progestin medication which is used to treat recurrent and threatened miscarriage and to prevent premature labor in pregnant women.
Allyltestosterone, or 17α-allyltestosterone, also known as 17α-allylandrost-4-en-17β-ol-3-one, is a steroid derived from testosterone that was first synthesized in 1936 and was never marketed.
Anabolic steroids, also known more properly as anabolic–androgenic steroids (AAS), are steroidal androgens that include natural androgens like testosterone as well as synthetic androgens that are structurally related and have similar effects to testosterone.
Anabolism (from ἁνά, "upward" and βάλλειν, "to throw") is the set of metabolic pathways that construct molecules from smaller units.
An androgen (from Greek andr-, the stem of the word meaning "man") is any natural or synthetic steroid hormone which regulates the development and maintenance of male characteristics in vertebrates by binding to androgen receptors.
The androgen receptor (AR), also known as NR3C4 (nuclear receptor subfamily 3, group C, member 4), is a type of nuclear receptor that is activated by binding any of the androgenic hormones, including testosterone and dihydrotestosterone in the cytoplasm and then translocating into the nucleus.
A bioassay is an analytical method to determine concentration or potency of a substance by its effect on living cells or tissues.
In chemistry, a derivative is a compound that is derived from a similar compound by a chemical reaction.
Half maximal effective concentration (EC50) refers to the concentration of a drug, antibody or toxicant which induces a response halfway between the baseline and maximum after a specified exposure time.
Estrane is a C18 steroid derivative, with a gonane core.
The estrous cycle or oestrus cycle (derived from Latin oestrus 'frenzy', originally from Greek οἶστρος oîstros 'gadfly') is the recurring physiological changes that are induced by reproductive hormones in most mammalian therian females.
In chemistry, an ethyl group is an alkyl substituent derived from ethane (C2H6).
In organic chemistry, the term ethynyl designates.
Europe is a continent located entirely in the Northern Hemisphere and mostly in the Eastern Hemisphere.
A filly is a female horse that is too young to be called a mare.
The horse (Equus ferus caballus) is one of two extant subspecies of ''Equus ferus''.
In vitro (meaning: in the glass) studies are performed with microorganisms, cells, or biological molecules outside their normal biological context.
A mare is an adult female horse or other equine.
A methyl group is an alkyl derived from methane, containing one carbon atom bonded to three hydrogen atoms — CH3.
Metribolone (developmental code name R1881), also known as methyltrienolone, is a synthetic and orally active anabolic–androgenic steroid (AAS) and a 17α-alkylated nandrolone (19-nortestosterone) derivative which was never marketed for medical use but has been widely used in scientific research as a hot ligand in androgen receptor (AR) ligand binding assays (LBAs) and as a photoaffinity label for the AR.
Nandrolone, also known as 19-nortestosterone, is an androgen and anabolic steroid (AAS) which is used in the form of esters such as nandrolone decanoate (brand name Deca-Durabolin) and nandrolone phenylpropionate (brand name Durabolin).
Norethisterone, also known as norethindrone and sold under the brand names Aygestin and Primolut N among many others, is a progestin medication which is used in birth control pills, menopausal hormone therapy, and for the treatment of gynecological disorders.
Noretynodrel, or norethynodrel, sold under the brand name Enovid among others, is a progestin medication which was previously used in birth control pills and in the treatment of gynecological disorders but is now no longer marketed. It was available both alone and in combination with an estrogen. The medication is taken by mouth. Noretynodrel is a progestin, or a synthetic progestogen, and hence is an agonist of the progesterone receptor, the biological target of progestogens like progesterone. It is a relatively weak progestogen. The medication has weak estrogenic activity, no or only very weak androgenic activity, and no other important hormonal activity. It is a prodrug of various active metabolites in the body, such as norethisterone among others. Noretynodrel was introduced for medical use in 1957. It was specifically approved at this time in combination with mestranol for the treatment of gynecological and menstrual disorders. Subsequently, in 1960, this formulation was approved for use as a birth control pill. It was the first birth control pill to be introduced, and was followed by birth control pills containing norethisterone and other progestins shortly thereafter. Due to its nature as a relatively weak progestogen, noretynodrel is no longer used in medicine. As such, it is no longer marketed.
Norgestrel, sold under the brand name Ovral among others, is a progestin medication which is used in birth control pills and in menopausal hormone therapy.
Norgestrienone, sold under the brand names Ogyline, Planor, and Miniplanor, is a progestin medication which has been used in birth control pills, sometimes in combination with ethinylestradiol.
In biology, offspring are the young born of living organisms, produced either by a single organism or, in the case of sexual reproduction, two organisms.
In chemistry, an organic compound is generally any chemical compound that contains carbon.
The pharmaceutical industry (or medicine industry) is the commercial industry that discovers, develops, produces, and markets drugs or pharmaceutical drugs for use as different types of medicine and medications.
A pig is any of the animals in the genus Sus, within the even-toed ungulate family Suidae.
Pregnancy, also known as gestation, is the time during which one or more offspring develops inside a woman.
Progesterone (P4) is an endogenous steroid and progestogen sex hormone involved in the menstrual cycle, pregnancy, and embryogenesis of humans and other species.
The progesterone receptor (PR), also known as NR3C3 or nuclear receptor subfamily 3, group C, member 3, is a protein found inside cells.
A progestin is a type of medication which is used most commonly in hormonal birth control and menopausal hormone therapy.
Progestogens, also sometimes spelled progestagens or gestagens, are a class of steroid hormones that bind to and activate the progesterone receptor (PR).
Roussel Uclaf S.A. was a French pharmaceutical company and one of several predecessor companies of today's Sanofi.
A stallion is a male horse that has not been gelded (castrated).
A steroid is a biologically active organic compound with four rings arranged in a specific molecular configuration.
A structural analog, also known as a chemical analog or simply an analog, is a compound having a structure similar to that of another compound, but differing from it in respect to a certain component.
commented out as it doesn't appear to be immediately relevant & it is in the wrong place if it is relevant-->The structure–activity relationship (SAR) is the relationship between the chemical or 3D structure of a molecule and its biological activity.
Testosterone is the primary male sex hormone and an anabolic steroid.
Testosterone is a medication and naturally occurring steroid hormone.
Trademark distinctiveness is an important concept in the law governing trademarks and service marks.
Trenbolone is an androgen and anabolic steroid (AAS) of the nandrolone group which itself was never marketed.
The United States of America (USA), commonly known as the United States (U.S.) or America, is a federal republic composed of 50 states, a federal district, five major self-governing territories, and various possessions.
Veterinary medicine is the branch of medicine that deals with the prevention, diagnosis and treatment of disease, disorder and injury in non-human animals.
Virilization or masculinization is the biological development of sex differences, changes that make a male body different from a female body.
Yeasts are eukaryotic, single-celled microorganisms classified as members of the fungus kingdom.
A 17α-alkylated anabolic steroid is a synthetic anabolic–androgenic steroid (AAS) that features an alkyl group, specifically a methyl or ethyl group, at the C17α position.
17α-Allyl-19-nortestosterone, also known as 3-ketoallylestrenol or as 17α-allylestr-4-en-17β-ol-3-one, is a progestin which was never marketed.