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128 relations: AA amyloidosis, Acute-phase protein, Adrenal gland, AL amyloidosis, Alkaline phosphatase, Alzheimer's disease, Amino acid, Amylin, Amyloid, Amyloid beta, Amyloid precursor protein, Apolipoprotein A1, Atrial natriuretic peptide, Atrioventricular block, Autonomic neuropathy, Autopsy, Beta sheet, Beta-2 microglobulin, Biopsy, Blood urea nitrogen, Bovine spongiform encephalopathy, Calcitonin, Cardiology, Carpal tunnel syndrome, Cerebral amyloid angiopathy, Chronic kidney disease, Coeliac disease, Congo red, Corneal dystrophy, Creutzfeldt–Jakob disease, Cystatin C, Developed country, Diabetes mellitus, Diabetes mellitus type 2, Dialysis, Diarrhea, Dysphagia, Dystrophic calcification, Echocardiography, Electrocardiography, Endocrinology, Enzyme, Factor X, Familial amyloid neuropathy, Familial amyloid polyneuropathy, Familial Mediterranean fever, Familial renal amyloidosis, Fibrinogen alpha chain, Gel electrophoresis of proteins, Gelsolin, ..., Genetic disorder, Genetics, Glycosaminoglycan, H&E stain, Haemodialysis-associated amyloidosis, Heart, Heart failure, Hepatomegaly, Howell–Jolly body, Hydrophobe, Hypothyroidism, Idiopathic disease, Immunoglobulin light chain, Inclusion bodies, Intestinal villus, Isoelectric focusing, Isolated atrial amyloidosis, ITM2B, Lattice corneal dystrophy, LECT2, LECT2 amyloidosis, Lysozyme, Macroglossia, Major histocompatibility complex, Malabsorption, Mass effect (medicine), Medullary thyroid cancer, Melphalan, Meninges, Michael York, Micrograph, Microscopy, Multiple myeloma, Mutation, Nephrotic syndrome, Obstructive sleep apnea, Oligomer, Oncostatin M receptor, Online Mendelian Inheritance in Man, Organ transplantation, Organomegaly, Orthostatic hypotension, Pancreas, Peptide synthesis, Plasma cell dyscrasia, Polarization (waves), Polyneuropathy, Primary cutaneous amyloidosis, Prion, PRNP, Prolactin, Prolactinoma, Protease, Protein, Proteinuria, Proteolysis, Proteopathy, Purpura, Rheumatology, Scrapie, Secondary cutaneous amyloidosis, Serum amyloid A, Serum amyloid P component, Sinoatrial node, Splenomegaly, Supercentenarian, Synovial membrane, Synovitis, Systemic disease, Systemic inflammation, TGFBI, Therapy, Thioflavin, Thrombin, Thyroid, Transaminase, Transthyretin, Wild-type transthyretin amyloid. Expand index (78 more) »
AA amyloidosis
AA amyloidosis is a form of amyloidosis, a disease characterized by the abnormal deposition of fibers of insoluble protein in the extracellular space of various tissues and organs.
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Acute-phase protein
Acute-phase proteins (APPs) are a class of proteins whose plasma concentrations increase (positive acute-phase proteins) or decrease (negative acute-phase proteins) in response to inflammation.
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Adrenal gland
The adrenal glands (also known as suprarenal glands) are endocrine glands that produce a variety of hormones including adrenaline and the steroids aldosterone and cortisol.
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AL amyloidosis
Amyloid light-chain (AL) amyloidosis, primary systemic amyloidosis (PSA) or just primary amyloidosis is the most common form of systemic amyloidosis in the US.
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Alkaline phosphatase
Alkaline phosphatase (ALP, ALKP, ALPase, Alk Phos) or basic phosphatase is a homodimeric protein enzyme of 86 kilodaltons.
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Alzheimer's disease
Alzheimer's disease (AD), also referred to simply as Alzheimer's, is a chronic neurodegenerative disease that usually starts slowly and worsens over time.
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Amino acid
Amino acids are organic compounds containing amine (-NH2) and carboxyl (-COOH) functional groups, along with a side chain (R group) specific to each amino acid.
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Amylin
Amylin, or islet amyloid polypeptide (IAPP), is a 37-residue peptide hormone.
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Amyloid
Amyloids are aggregates of proteins that become folded into a shape that allows many copies of that protein to stick together forming fibrils.
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Amyloid beta
Amyloid beta (Aβ or Abeta) denotes peptides of 36–43 amino acids that are crucially involved in Alzheimer's disease as the main component of the amyloid plaques found in the brains of Alzheimer patients.
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Amyloid precursor protein
Amyloid precursor protein (APP) is an integral membrane protein expressed in many tissues and concentrated in the synapses of neurons.
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Apolipoprotein A1
Apolipoprotein A1 is a protein that in humans is encoded by the APOA1 gene.
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Atrial natriuretic peptide
Atrial natriuretic peptide (ANP) or Atrial natriuretic factor (ANF) is a peptide hormone which reduces an expanded extracellular fluid (ECF) volume by increasing renal sodium excretion.
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Atrioventricular block
Atrioventricular block (AV block) is a type of heart block in which the conduction between the atria and ventricles of the heart is impaired.
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Autonomic neuropathy
Autonomic neuropathy (also AN or AAN) is a form of polyneuropathy that affects the non-voluntary, non-sensory nervous system (i.e., the autonomic nervous system), affecting mostly the internal organs such as the bladder muscles, the cardiovascular system, the digestive tract, and the genital organs.
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Autopsy
An autopsy (post-mortem examination, obduction, necropsy, or autopsia cadaverum) is a highly specialized surgical procedure that consists of a thorough examination of a corpse by dissection to determine the cause and manner of death or to evaluate any disease or injury that may be present for research or educational purposes.
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Beta sheet
The β-sheet (also β-pleated sheet) is a common motif of regular secondary structure in proteins.
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Beta-2 microglobulin
β2 microglobulin also known as B2M is a component of MHC class I molecules, MHC class I molecules have α1, α2, and α3 proteins which are present on all nucleated cells (excludes red blood cells).
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Biopsy
A biopsy is a medical test commonly performed by a surgeon, interventional radiologist, or an interventional cardiologist involving extraction of sample cells or tissues for examination to determine the presence or extent of a disease.
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Blood urea nitrogen
Blood urea nitrogen (BUN) is a medical test that measures the amount of urea nitrogen found in blood.
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Bovine spongiform encephalopathy
Bovine spongiform encephalopathy (BSE), commonly known as mad cow disease, is a transmissible spongiform encephalopathy and fatal neurodegenerative disease in cattle that may be passed to humans who have eaten infected flesh.
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Calcitonin
Calcitonin (also known as thyrocalcitonin) is a 32-amino acid linear polypeptide hormone that is produced in humans primarily by the parafollicular cells (also known as C-cells) of the thyroid gland, and in many other animals in the ultimopharyngeal body.
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Cardiology
Cardiology (from Greek καρδίᾱ kardiā, "heart" and -λογία -logia, "study") is a branch of medicine dealing with disorders of the heart as well as parts of the circulatory system.
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Carpal tunnel syndrome
Carpal tunnel syndrome (CTS) is a medical condition due to compression of the median nerve as it travels through the wrist at the carpal tunnel.
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Cerebral amyloid angiopathy
Cerebral amyloid angiopathy (CAA), also known as congophilic angiopathy, is a form of angiopathy in which amyloid deposits form in the walls of the blood vessels of the central nervous system.
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Chronic kidney disease
Chronic kidney disease (CKD) is a type of kidney disease in which there is gradual loss of kidney function over a period of months or years.
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Coeliac disease
Coeliac disease, also spelled celiac disease, is a long-term autoimmune disorder that primarily affects the small intestine.
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Congo red
Congo red is an organic compound, the sodium salt of 3,3′-(-4,4′-diyl)bis(4-aminonaphthalene-1-sulfonic acid).
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Corneal dystrophy
Corneal dystrophy is a group of rare hereditary disorders characterised by bilateral abnormal deposition of substances in the transparent front part of the eye called the cornea.
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Creutzfeldt–Jakob disease
Creutzfeldt–Jakob disease (CJD) is a universally fatal brain disorder.
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Cystatin C
Cystatin C or cystatin 3 (formerly gamma trace, post-gamma-globulin, or neuroendocrine basic polypeptide), a protein encoded by the CST3 gene, is mainly used as a biomarker of kidney function.
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Developed country
A developed country, industrialized country, more developed country, or "more economically developed country" (MEDC), is a sovereign state that has a highly developed economy and advanced technological infrastructure relative to other less industrialized nations.
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Diabetes mellitus
Diabetes mellitus (DM), commonly referred to as diabetes, is a group of metabolic disorders in which there are high blood sugar levels over a prolonged period.
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Diabetes mellitus type 2
Diabetes mellitus type 2 (also known as type 2 diabetes) is a long-term metabolic disorder that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.
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Dialysis
In medicine, dialysis (from Greek διάλυσις, diàlysis, "dissolution"; from διά, dià, "through", and λύσις, lỳsis, "loosening or splitting") is the process of removing excess water, solutes and toxins from the blood in those whose native kidneys have lost the ability to perform these functions in a natural way.
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Diarrhea
Diarrhea, also spelled diarrhoea, is the condition of having at least three loose or liquid bowel movements each day.
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Dysphagia
Dysphagia is the medical term for the symptom of difficulty in swallowing.
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Dystrophic calcification
Dystrophic calcification (DC) is the calcification occurring in degenerated or necrotic tissue, as in hyalinized scars, degenerated foci in leiomyomas, and caseous nodules.
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Echocardiography
An echocardiogram, often referred to as a cardiac echo or simply an echo, is a sonogram of the heart.
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Electrocardiography
Electrocardiography (ECG or EKG) is the process of recording the electrical activity of the heart over a period of time using electrodes placed on the skin.
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Endocrinology
Endocrinology (from endocrine + -ology) is a branch of biology and medicine dealing with the endocrine system, its diseases, and its specific secretions known as hormones.
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Enzyme
Enzymes are macromolecular biological catalysts.
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Factor X
Factor X, also known by the eponym Stuart–Prower factor, is an enzyme of the coagulation cascade.
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Familial amyloid neuropathy
The familial amyloid neuropathies (or familial amyloidotic neuropathies, neuropathic heredofamilial amyloidosis, familial amyloid polyneuropathy) are a rare group of autosomal dominant diseases wherein the autonomic nervous system and/or other nerves are compromised by protein aggregation and/or amyloid fibril formation.
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Familial amyloid polyneuropathy
Familial amyloid polyneuropathy (FAP), also called transthyretin-related hereditary amyloidosis, transthyretin amyloidosis abbreviated also as ATTR (hereditary form), or Corino de Andrade's disease, is an autosomal dominant neurodegenerative disease.
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Familial Mediterranean fever
Familial Mediterranean fever (FMF) is a hereditary inflammatory disorder.
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Familial renal amyloidosis
Familial renal amyloidosis (or familial visceral amyloidosis, or hereditary amyloid nephropathy) is a form of amyloidosis primarily presenting in the kidney.
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Fibrinogen alpha chain
Fibrinogen alpha chain is a protein that in humans is encoded by the FGA gene.
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Gel electrophoresis of proteins
Protein electrophoresis is a method for analysing the proteins in a fluid or an extract.
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Gelsolin
Gelsolin is an actin-binding protein that is a key regulator of actin filament assembly and disassembly.
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Genetic disorder
A genetic disorder is a genetic problem caused by one or more abnormalities in the genome.
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Genetics
Genetics is the study of genes, genetic variation, and heredity in living organisms.
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Glycosaminoglycan
Glycosaminoglycans (GAGs) or mucopolysaccharides are long unbranched polysaccharides consisting of a repeating disaccharide unit.
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H&E stain
Hematoxylin and eosin stain or haematoxylin and eosin stain (H&E stain or HE stain) is one of the principal stains in histology.
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Haemodialysis-associated amyloidosis
Haemodialysis-associated amyloidosis is a form of systemic amyloidosis associated with chronic kidney failure.
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Heart
The heart is a muscular organ in most animals, which pumps blood through the blood vessels of the circulatory system.
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Heart failure
Heart failure (HF), often referred to as congestive heart failure (CHF), is when the heart is unable to pump sufficiently to maintain blood flow to meet the body's needs.
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Hepatomegaly
Hepatomegaly is the condition of having an enlarged liver.
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Howell–Jolly body
A Howell–Jolly body is a histopathological finding of basophilic nuclear remnants (clusters of DNA) in circulating erythrocytes.
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Hydrophobe
In chemistry, hydrophobicity is the physical property of a molecule (known as a hydrophobe) that is seemingly repelled from a mass of water.
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Hypothyroidism
Hypothyroidism, also called underactive thyroid or low thyroid, is a disorder of the endocrine system in which the thyroid gland does not produce enough thyroid hormone.
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Idiopathic disease
An idiopathic disease is any disease with an unknown cause or mechanism of apparently spontaneous origin.
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Immunoglobulin light chain
The immunoglobulin light chain is the small polypeptide subunit of an antibody (immunoglobulin).
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Inclusion bodies
Inclusion bodies, sometimes called elementary bodies, are nuclear or cytoplasmic aggregates of stable substances, usually proteins.
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Intestinal villus
Intestinal villi (singular: villus) are small, finger-like projections that extend into the lumen of the small intestine.
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Isoelectric focusing
Isoelectric focusing (IEF), also known as electrofocusing, is a technique for separating different molecules by differences in their isoelectric point (pI).
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Isolated atrial amyloidosis
Isolated atrial amyloidosis is a form of amyloidosis affecting the atria of the heart.
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ITM2B
Integral membrane protein 2B (ITM2B or BRI2) is a protein that in humans is encoded by the ITM2B gene.
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Lattice corneal dystrophy
Lattice corneal dystrophy type, also known as Biber-Haab-Dimmer dystrophy, is a rare form of corneal dystrophy.
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LECT2
Leukocyte cell-derived chemotaxin-2 (LECT2) is a protein first described in 1996 as a chemotactic factor for neutrophils, i.e. it stimulated human neutrophils to move directionally in an in vitro assay system.
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LECT2 amyloidosis
LECT2 Amyloidosis (ALECT2) is a form of amyloidosis caused by the LECT2 protein.
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Lysozyme
Lysozyme, also known as muramidase or N-acetylmuramide glycanhydrolase is an antimicrobial enzyme produced by animals that forms part of the innate immune system.
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Macroglossia
Macroglossia is the medical term for an unusually large tongue.
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Major histocompatibility complex
The major histocompatibility complex (MHC) is a set of cell surface proteins essential for the acquired immune system to recognize foreign molecules in vertebrates, which in turn determines histocompatibility.
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Malabsorption
Malabsorption is a state arising from abnormality in absorption of food nutrients across the gastrointestinal (GI) tract.
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Mass effect (medicine)
In medicine, a mass effect is the effect of a growing mass that results in secondary pathological effects by pushing on or displacing surrounding tissue.
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Medullary thyroid cancer
Medullary thyroid cancer (MTC) is a form of thyroid carcinoma which originates from the parafollicular cells (C cells), which produce the hormone calcitonin.
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Melphalan
Melphalan (trade name Alkeran, in former USSR also known as Sarcolysin) is a chemotherapy drug belonging to the class of nitrogen mustard alkylating agents.
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Meninges
The meninges (singular: meninx, from membrane, adjectival: meningeal) are the three membranes that envelop the brain and spinal cord.
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Michael York
Michael York, OBE (born Michael Hugh Johnson; 27 March 1942) is an English actor.
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Micrograph
A micrograph or photomicrograph is a photograph or digital image taken through a microscope or similar device to show a magnified image of an item.
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Microscopy
Microscopy is the technical field of using microscopes to view objects and areas of objects that cannot be seen with the naked eye (objects that are not within the resolution range of the normal eye).
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Multiple myeloma
Multiple myeloma, also known as plasma cell myeloma, is a cancer of plasma cells, a type of white blood cell normally responsible for producing antibodies.
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Mutation
In biology, a mutation is the permanent alteration of the nucleotide sequence of the genome of an organism, virus, or extrachromosomal DNA or other genetic elements.
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Nephrotic syndrome
Nephrotic syndrome is a collection of symptoms due to kidney damage.
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Obstructive sleep apnea
Obstructive sleep apnea (OSA) is the most common type of sleep apnea and is caused by complete or partial obstructions of the upper airway.
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Oligomer
An oligomer (oligo-, "a few" + -mer, "parts") is a molecular complex of chemicals that consists of a few monomer units, in contrast to a polymer, where the number of monomers is, in principle, infinite.
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Oncostatin M receptor
Oncostatin-M specific receptor subunit beta also known as the oncostatin M receptor, is one of the receptor proteins for oncostatin M, that in humans is encoded by the OSMR gene.
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Online Mendelian Inheritance in Man
Online Mendelian Inheritance in Man (OMIM) is a continuously updated catalog of human genes and genetic disorders and traits, with a particular focus on the gene-phenotype relationship.
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Organ transplantation
Organ transplantation is a medical procedure in which an organ is removed from one body and placed in the body of a recipient, to replace a damaged or missing organ.
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Organomegaly
Organomegaly is the abnormal enlargement of organs.
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Orthostatic hypotension
Orthostatic hypotension, also known as postural hypotension, occurs when a person's blood pressure falls when suddenly standing up from a lying or sitting position.
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Pancreas
The pancreas is a glandular organ in the digestive system and endocrine system of vertebrates.
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Peptide synthesis
In organic chemistry, peptide synthesis is the production of peptides, compounds where multiple amino acids are linked via amide bonds, also known as peptide bonds.
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Plasma cell dyscrasia
Plasma cell dyscrasias (also termed plasma cell disorders and plasma cell proliferative diseases) are a spectrum of progressively more severe monoclonal gammopathies in which a clone or multiple clones of pre-malignant or malignant plasma cells (sometimes in association with lymphoplasmacytoid cells or B lymphocytes) over-produce and secrete into the blood stream a myeloma protein, i.e. an abnormal monoclonal antibody or portion thereof.
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Polarization (waves)
Polarization (also polarisation) is a property applying to transverse waves that specifies the geometrical orientation of the oscillations.
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Polyneuropathy
Polyneuropathy (poly- + neuro- + -pathy) is damage or disease affecting peripheral nerves (peripheral neuropathy) in roughly the same areas on both sides of the body, featuring weakness, numbness, and burning pain.
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Primary cutaneous amyloidosis
Primary cutaneous amyloidosis is a form of amyloidosis associated with oncostatin M receptor.
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Prion
Prions are misfolded proteins that are associated with several fatal neurodegenerative diseases in animals and humans.
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PRNP
PRNP (PRioN Protein) is the human gene encoding for the major prion protein PrP (for prion protein), also known as CD230 (cluster of differentiation 230).
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Prolactin
Prolactin (PRL), also known as luteotropic hormone or luteotropin, is a protein that is best known for its role in enabling mammals, usually females, to produce milk.
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Prolactinoma
A prolactinoma is a benign tumor (adenoma) of the pituitary gland that produces a hormone called prolactin.
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Protease
A protease (also called a peptidase or proteinase) is an enzyme that performs proteolysis: protein catabolism by hydrolysis of peptide bonds.
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Protein
Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.
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Proteinuria
Proteinuria is the presence of excess proteins in the urine.
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Proteolysis
Proteolysis is the breakdown of proteins into smaller polypeptides or amino acids.
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Proteopathy
In medicine, proteopathy (Proteo-; -pathy; proteopathies pl.; proteopathic adj.) refers to a class of diseases in which certain proteins become structurally abnormal, and thereby disrupt the function of cells, tissues and organs of the body.
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Purpura
Purpura is a condition of red or purple discolored spots on the skin that do not blanch on applying pressure.
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Rheumatology
Rheumatology (Greek ρεύμα, rheuma, flowing current) is a branch of medicine devoted to the diagnosis and therapy of rheumatic diseases.
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Scrapie
Scrapie is a fatal, degenerative disease that affects the nervous systems of sheep and goats.
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Secondary cutaneous amyloidosis
Secondary cutaneous amyloidosis is a skin condition that occurs following PUVA therapy and in benign and malignant cutaneous neoplasms in which deopsits of amyloid may be found.
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Serum amyloid A
Serum amyloid A (SAA) proteins are a family of apolipoproteins associated with high-density lipoprotein (HDL) in plasma.
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Serum amyloid P component
The serum amyloid P component (SAP) is the identical serum form of amyloid P component (AP), a 25kDa pentameric protein first identified as the pentagonal constituent of in vivo pathological deposits called "amyloid".
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Sinoatrial node
The sinoatrial node (SA node), also known as sinus node, is a group of cells located in the wall of the right atrium of the heart.
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Splenomegaly
Splenomegaly is an enlargement of the spleen.
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Supercentenarian
A supercentenarian (sometimes hyphenated as super-centenarian) is someone who has lived to or passed their 110th birthday.
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Synovial membrane
The synovial membrane (also known as synovium or stratum synoviale) is a specialized connective tissue that lines the inner surface of capsules of synovial joints and tendon sheath.
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Synovitis
Synovitis is the medical term for inflammation of the synovial membrane.
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Systemic disease
A systemic disease is one that affects a number of organs and tissues, or affects the body as a whole.
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Systemic inflammation
Chronic systemic inflammation (SI) is the result of release of pro-inflammatory cytokines from immune-related cells and the chronic activation of the innate immune system.
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TGFBI
Transforming growth factor, beta-induced, 68kDa, also known as TGFBI (initially called BIGH3, BIG-H3), is a protein which in humans is encoded by the TGFBI gene, locus 5q31.
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Therapy
Therapy (often abbreviated tx, Tx, or Tx) is the attempted remediation of a health problem, usually following a diagnosis.
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Thioflavin
Thioflavins are dyes used for histology staining and biophysical studies of protein aggregation.
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Thrombin
Thrombin (fibrinogenase, thrombase, thrombofort, topical, thrombin-C, tropostasin, activated blood-coagulation factor II, blood-coagulation factor IIa, factor IIa, E thrombin, beta-thrombin, gamma-thrombin) is a serine protease, an enzyme that, in humans, is encoded by the F2 gene.
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Thyroid
The thyroid gland, or simply the thyroid, is an endocrine gland in the neck, consisting of two lobes connected by an isthmus.
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Transaminase
Transaminases or aminotransferases are enzymes that catalyze a transamination reaction between an amino acid and an α-keto acid.
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Transthyretin
Transthyretin (TTR) is a transport protein in the serum and cerebrospinal fluid that carries the thyroid hormone thyroxine (T4) and retinol-binding protein bound to retinol.
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Wild-type transthyretin amyloid
Wild-type transthyretin amyloid (WTTA), also known as senile systemic amyloidosis (SSA) and abbreviated as ATTR, is a disease that typically affects the heart and tendons of elderly people.
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ATTR, Abercrombie's disease, Abercrombie's syndrome, Amyloid degeneration, Amyloidodis, Amyloidoma, Amyloidoses, Amyloidosis - familial amyloid polyneuropathy affecting skin, Amyloidosis secondary systemic, Bacony disease, Cellulose disease, Familial amyloidosis, Heredofamilial systemic affecting skin amyloidosis, Hyaloid disease, Lardaceous disease, Localized amyloidosis, Virchow's disease, Waxy disease.
References
[1] https://en.wikipedia.org/wiki/Amyloidosis
