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Molecular Structure of Nucleic Acids: A Structure for Deoxyribose Nucleic Acid

Index Molecular Structure of Nucleic Acids: A Structure for Deoxyribose Nucleic Acid

"Molecular Structure of Nucleic Acids: A Structure for Deoxyribose Nucleic Acid" was the first article published to describe the discovery of the double helix structure of DNA, using X-ray diffraction and the mathematics of a helix transform. [1]

62 relations: Adenine, Alex Stokes, Alpha helix, Amino acid, Bacteriophage, Base pair, BBC, Biology, Biotechnology, Cavendish Laboratory, Comparison of nucleic acid simulation software, Crystallography, Cytosine, Denis Jordan, DNA, DNA replication, DNA sequencing, Erwin Chargaff, Erwin Schrödinger, Exploratorium, Francis Crick, Genetic code, Genetics, Guanine, Helix, Herbert Wilson, Human Genome Project, Hydrogen bond, James Watson, John Masson Gulland, King's College London, Lawrence Bragg, Life, Life Story (1987 film), Linus Pauling, Maurice Wilkins, Max Delbrück, Max Perutz, Medical Research Council (United Kingdom), Medicine, Miles from Tomorrowland, Molecular biology, National Institutes of Health, Nature (journal), Nobel Prize in Physiology or Medicine, Nucleic acid double helix, Nucleotide, Organism, Paracrystalline, Protein, ..., Quantum mechanics, Raymond Gosling, Rosalind Franklin, Scientific journal, Scientific literature, The Double Helix, Thymine, University of Cambridge, University of Nottingham, What Is Life?, X-ray crystallography, X-ray scattering techniques. Expand index (12 more) »

Adenine

Adenine (A, Ade) is a nucleobase (a purine derivative).

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Alex Stokes

Alexander (Alec) Rawson Stokes (27 June 1919 – 5 February 2003) was a co-author of the second of the three papers published sequentially in Nature on 25 April 1953 announcing the presumed molecular structure of DNA.

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Alpha helix

The alpha helix (α-helix) is a common motif in the secondary structure of proteins and is a righthand-spiral conformation (i.e. helix) in which every backbone N−H group donates a hydrogen bond to the backbone C.

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Amino acid

Amino acids are organic compounds containing amine (-NH2) and carboxyl (-COOH) functional groups, along with a side chain (R group) specific to each amino acid.

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Bacteriophage

A bacteriophage, also known informally as a phage, is a virus that infects and replicates within Bacteria and Archaea.

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Base pair

A base pair (bp) is a unit consisting of two nucleobases bound to each other by hydrogen bonds.

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BBC

The British Broadcasting Corporation (BBC) is a British public service broadcaster.

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Biology

Biology is the natural science that studies life and living organisms, including their physical structure, chemical composition, function, development and evolution.

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Biotechnology

Biotechnology is the broad area of science involving living systems and organisms to develop or make products, or "any technological application that uses biological systems, living organisms, or derivatives thereof, to make or modify products or processes for specific use" (UN Convention on Biological Diversity, Art. 2).

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Cavendish Laboratory

The Cavendish Laboratory is the Department of Physics at the University of Cambridge, and is part of the School of Physical Sciences.

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Comparison of nucleic acid simulation software

This is a list of computer programs that are used for nucleic acids simulations.

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Crystallography

Crystallography is the experimental science of determining the arrangement of atoms in crystalline solids (see crystal structure).

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Cytosine

Cytosine (C) is one of the four main bases found in DNA and RNA, along with adenine, guanine, and thymine (uracil in RNA).

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Denis Jordan

Denis Oswald Jordan AO FAA FRACI (23 September 1914, London – 12 February 1982, St Georges, South Australia) was an Anglo-Australian chemist with a distinguished career as a researcher and lecturer in Chemistry at both University College Nottingham (1940-53) and the University of Adelaide, where he was Angas Professor of Chemistry from 1958 to 1982.

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DNA

Deoxyribonucleic acid (DNA) is a thread-like chain of nucleotides carrying the genetic instructions used in the growth, development, functioning and reproduction of all known living organisms and many viruses.

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DNA replication

In molecular biology, DNA replication is the biological process of producing two identical replicas of DNA from one original DNA molecule.

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DNA sequencing

DNA sequencing is the process of determining the precise order of nucleotides within a DNA molecule.

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Erwin Chargaff

Erwin Chargaff (11 August 1905 – 20 June 2002) was an Austro-Hungarian biochemist who immigrated to the United States during the Nazi era and was a professor of biochemistry at Columbia University medical school.

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Erwin Schrödinger

Erwin Rudolf Josef Alexander Schrödinger (12 August 1887 – 4 January 1961), sometimes written as or, was a Nobel Prize-winning Austrian physicist who developed a number of fundamental results in the field of quantum theory, which formed the basis of wave mechanics: he formulated the wave equation (stationary and time-dependent Schrödinger equation) and revealed the identity of his development of the formalism and matrix mechanics.

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Exploratorium

The Exploratorium is a museum in San Francisco that allows visitors to explore the world through science, art, and human perception.

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Francis Crick

Francis Harry Compton Crick (8 June 1916 – 28 July 2004) was a British molecular biologist, biophysicist, and neuroscientist, most noted for being a co-discoverer of the structure of the DNA molecule in 1953 with James Watson, work which was based partly on fundamental studies done by Rosalind Franklin, Raymond Gosling and Maurice Wilkins.

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Genetic code

The genetic code is the set of rules used by living cells to translate information encoded within genetic material (DNA or mRNA sequences) into proteins.

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Genetics

Genetics is the study of genes, genetic variation, and heredity in living organisms.

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Guanine

Guanine (or G, Gua) is one of the four main nucleobases found in the nucleic acids DNA and RNA, the others being adenine, cytosine, and thymine (uracil in RNA).

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Helix

A helix, plural helixes or helices, is a type of smooth space curve, i.e. a curve in three-dimensional space.

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Herbert Wilson

Herbert Rees Wilson FRSE (20 March 1929 – 22 May 2008) was a physicist, who was one of the team who worked on the structure of DNA at King's College London, under the direction of Sir John Randall.

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Human Genome Project

The Human Genome Project (HGP) was an international scientific research project with the goal of determining the sequence of nucleotide base pairs that make up human DNA, and of identifying and mapping all of the genes of the human genome from both a physical and a functional standpoint.

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Hydrogen bond

A hydrogen bond is a partially electrostatic attraction between a hydrogen (H) which is bound to a more electronegative atom such as nitrogen (N), oxygen (O), or fluorine (F), and another adjacent atom bearing a lone pair of electrons.

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James Watson

James Dewey Watson (born April 6, 1928) is an American molecular biologist, geneticist and zoologist, best known as one of the co-discoverers of the structure of DNA in 1953 with Francis Crick and Rosalind Franklin.

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John Masson Gulland

Prof John Masson Gulland FRS FRSE FRIC (1898 – 1947) was a Scottish chemist and biochemist.

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King's College London

King's College London (informally King's or KCL) is a public research university located in London, United Kingdom, and a founding constituent college of the federal University of London.

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Lawrence Bragg

Sir William Lawrence Bragg, (31 March 1890 – 1 July 1971) was an Australian-born British physicist and X-ray crystallographer, discoverer (1912) of Bragg's law of X-ray diffraction, which is basic for the determination of crystal structure.

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Life

Life is a characteristic that distinguishes physical entities that do have biological processes, such as signaling and self-sustaining processes, from those that do not, either because such functions have ceased, or because they never had such functions and are classified as inanimate.

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Life Story (1987 film)

Life Story (known as The Race for the Double Helix or Double Helix in the United States) is a 1987 TV film dramatisation of the discovery of the structure of DNA in 1953.

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Linus Pauling

Linus Carl Pauling (February 28, 1901 – August 19, 1994) was an American chemist, biochemist, peace activist, author, educator, and husband of American human rights activist Ava Helen Pauling.

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Maurice Wilkins

Maurice Hugh Frederick Wilkins (15 December 1916 – 5 October 2004) was a New Zealand-born British physicist and molecular biologist, and Nobel laureate whose research contributed to the scientific understanding of phosphorescence, isotope separation, optical microscopy and X-ray diffraction, and to the development of radar.

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Max Delbrück

Max Ludwig Henning Delbrück (September 4, 1906 – March 9, 1981), a German–American biophysicist, helped launch the molecular biology research program in the late 1930s.

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Max Perutz

Max Ferdinand Perutz (19 May 1914 – 6 February 2002) was an Austrian-born British molecular biologist, who shared the 1962 Nobel Prize for Chemistry with John Kendrew, for their studies of the structures of haemoglobin and myoglobin.

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Medical Research Council (United Kingdom)

The Medical Research Council (MRC) is responsible for co-coordinating and funding medical research in the United Kingdom.

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Medicine

Medicine is the science and practice of the diagnosis, treatment, and prevention of disease.

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Miles from Tomorrowland

Miles from Tomorrowland (titled Miles from Tomorrow in the UK) is a CGI animated Disney Junior series.

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Molecular biology

Molecular biology is a branch of biology which concerns the molecular basis of biological activity between biomolecules in the various systems of a cell, including the interactions between DNA, RNA, proteins and their biosynthesis, as well as the regulation of these interactions.

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National Institutes of Health

The National Institutes of Health (NIH) is the primary agency of the United States government responsible for biomedical and public health research, founded in the late 1870s.

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Nature (journal)

Nature is a British multidisciplinary scientific journal, first published on 4 November 1869.

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Nobel Prize in Physiology or Medicine

The Nobel Prize in Physiology or Medicine (Nobelpriset i fysiologi eller medicin), administered by the Nobel Foundation, is awarded once a year for outstanding discoveries in the fields of life sciences and medicine.

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Nucleic acid double helix

In molecular biology, the term double helix refers to the structure formed by double-stranded molecules of nucleic acids such as DNA.

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Nucleotide

Nucleotides are organic molecules that serve as the monomer units for forming the nucleic acid polymers deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), both of which are essential biomolecules within all life-forms on Earth.

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Organism

In biology, an organism (from Greek: ὀργανισμός, organismos) is any individual entity that exhibits the properties of life.

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Paracrystalline

Paracrystalline materials are defined as having short- and medium-range ordering in their lattice (similar to the liquid crystal phases) but lacking crystal-like long-range ordering at least in one direction.

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Protein

Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.

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Quantum mechanics

Quantum mechanics (QM; also known as quantum physics, quantum theory, the wave mechanical model, or matrix mechanics), including quantum field theory, is a fundamental theory in physics which describes nature at the smallest scales of energy levels of atoms and subatomic particles.

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Raymond Gosling

Raymond George Gosling (15 July 1926 – 18 May 2015) was a British scientist.

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Rosalind Franklin

Rosalind Elsie Franklin (25 July 192016 April 1958) was an English chemist and X-ray crystallographer who made contributions to the understanding of the molecular structures of DNA (deoxyribonucleic acid), RNA (ribonucleic acid), viruses, coal, and graphite.

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Scientific journal

In academic publishing, a scientific journal is a periodical publication intended to further the progress of science, usually by reporting new research.

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Scientific literature

Scientific literature comprises scholarly publications that report original empirical and theoretical work in the natural and social sciences, and within an academic field, often abbreviated as the literature.

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The Double Helix

The Double Helix: A Personal Account of the Discovery of the Structure of DNA is an autobiographical account of the discovery of the double helix structure of DNA written by James D. Watson and published in 1968.

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Thymine

---> Thymine (T, Thy) is one of the four nucleobases in the nucleic acid of DNA that are represented by the letters G–C–A–T.

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University of Cambridge

The University of Cambridge (informally Cambridge University)The corporate title of the university is The Chancellor, Masters, and Scholars of the University of Cambridge.

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University of Nottingham

The University of Nottingham is a public research university in Nottingham, United Kingdom.

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What Is Life?

What Is Life? The Physical Aspect of the Living Cell is a 1944 science book written for the lay reader by physicist Erwin Schrödinger.

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X-ray crystallography

X-ray crystallography is a technique used for determining the atomic and molecular structure of a crystal, in which the crystalline atoms cause a beam of incident X-rays to diffract into many specific directions.

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X-ray scattering techniques

X-ray scattering techniques are a family of non-destructive analytical techniques which reveal information about the crystal structure, chemical composition, and physical properties of materials and thin films.

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A Structure for Deoxyribose Nucleic Acid, Crick and Watson, Molecular Structure of Nucleic Acids, Molecular structure of Nucleic Acids, Molecular structure of nucleic acids, Molecular structure of nucleic acids: a structure for deoxyribose nucleic acid, Watson & Crick, Watson Crick, Watson and Crick, Watson and crick.

References

[1] https://en.wikipedia.org/wiki/Molecular_Structure_of_Nucleic_Acids:_A_Structure_for_Deoxyribose_Nucleic_Acid

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