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Protein splicing

Index Protein splicing

Protein splicing is an intramolecular reaction of a particular protein in which an internal protein segment (called an intein) is removed from a precursor protein with a ligation of C-terminal and N-terminal external proteins (called exteins) on both sides. [1]

Table of Contents

  1. 90 relations: Adenosine triphosphate, Allele, Allotopic expression, Amide, Amine, Amino acid, Amoebozoa, Antimicrobial, Antimycobacterial, Ascomycota, Asparagine, ATPase, Bacillus circulans, Basidiomycota, Binomial nomenclature, Biotechnology, C-terminus, Capsaspora, Chemical ligation, Chitin, Chlorophyta, Chloroplast, Choanoflagellate, Chytridiomycota, Cryptococcus, Cryptococcus gattii, Cryptococcus neoformans, Cyanobacteria, Cysteine, Cystine, Directionality (molecular biology), Dithiothreitol, DNA polymerase III holoenzyme, DnaB helicase, DnaE, Drug development, Elastin-like polypeptides, Enzyme inhibitor, Ester, Gene, Gene product, Gene therapy, Glomeromycota, Guanosine triphosphate, Hedgehog signaling pathway, Homing endonuclease, Homologous chromosome, Homology (biology), Horizontal gene transfer, Hydrophobe, ... Expand index (40 more) »

Adenosine triphosphate

Adenosine triphosphate (ATP) is a nucleotide that provides energy to drive and support many processes in living cells, such as muscle contraction, nerve impulse propagation, and chemical synthesis.

See Protein splicing and Adenosine triphosphate

Allele

An allele, or allelomorph, is a variant of the sequence of nucleotides at a particular location, or locus, on a DNA molecule.

See Protein splicing and Allele

Allotopic expression

Allotopic expression (AE) refers to expression of genes in the cell nucleus that normally are expressed only from the mitochondrial genome.

See Protein splicing and Allotopic expression

Amide

In organic chemistry, an amide, also known as an organic amide or a carboxamide, is a compound with the general formula, where R, R', and R″ represent any group, typically organyl groups or hydrogen atoms.

See Protein splicing and Amide

Amine

In chemistry, amines are compounds and functional groups that contain a basic nitrogen atom with a lone pair.

See Protein splicing and Amine

Amino acid

Amino acids are organic compounds that contain both amino and carboxylic acid functional groups.

See Protein splicing and Amino acid

Amoebozoa

Amoebozoa is a major taxonomic group containing about 2,400 described species of amoeboid protists, often possessing blunt, fingerlike, lobose pseudopods and tubular mitochondrial cristae.

See Protein splicing and Amoebozoa

Antimicrobial

An antimicrobial is an agent that kills microorganisms (microbicide) or stops their growth (bacteriostatic agent).

See Protein splicing and Antimicrobial

Antimycobacterial

An antimycobacterial is a type of medication used to treat Mycobacteria infections.

See Protein splicing and Antimycobacterial

Ascomycota

Ascomycota is a phylum of the kingdom Fungi that, together with the Basidiomycota, forms the subkingdom Dikarya.

See Protein splicing and Ascomycota

Asparagine

Asparagine (symbol Asn or N) is an α-amino acid that is used in the biosynthesis of proteins.

See Protein splicing and Asparagine

ATPase

ATPases (Adenosine 5'-TriPhosphatase, adenylpyrophosphatase, ATP monophosphatase, triphosphatase, SV40 T-antigen, ATP hydrolase, complex V (mitochondrial electron transport), (Ca2+ + Mg2+)-ATPase, HCO3−-ATPase, adenosine triphosphatase) are a class of enzymes that catalyze the decomposition of ATP into ADP and a free phosphate ion or the inverse reaction.

See Protein splicing and ATPase

Bacillus circulans

Bacillus circulans is a soil-dwelling human pathogen which has been associated with "septicemia, mixed abscess infections, and wound infections", as well as with meningitis.

See Protein splicing and Bacillus circulans

Basidiomycota

Basidiomycota is one of two large divisions that, together with the Ascomycota, constitute the subkingdom Dikarya (often referred to as the "higher fungi") within the kingdom Fungi.

See Protein splicing and Basidiomycota

Binomial nomenclature

In taxonomy, binomial nomenclature ("two-term naming system"), also called binary nomenclature, is a formal system of naming species of living things by giving each a name composed of two parts, both of which use Latin grammatical forms, although they can be based on words from other languages.

See Protein splicing and Binomial nomenclature

Biotechnology

Biotechnology is a multidisciplinary field that involves the integration of natural sciences and engineering sciences in order to achieve the application of organisms and parts thereof for products and services.

See Protein splicing and Biotechnology

C-terminus

The C-terminus (also known as the carboxyl-terminus, carboxy-terminus, C-terminal tail, carboxy tail, C-terminal end, or COOH-terminus) is the end of an amino acid chain (protein or polypeptide), terminated by a free carboxyl group (-COOH).

See Protein splicing and C-terminus

Capsaspora

Capsaspora is a monotypic genus containing the single species Capsaspora owczarzaki. C. owczarzaki is a single-celled eukaryote that occupies a key phylogenetic position in our understanding of the origin of animal multicellularity, as one of the closest unicellular relatives to animals.

See Protein splicing and Capsaspora

Chemical ligation

Chemical ligation is the chemoselective condensation of unprotected peptide segments enabled by the formation of a non-native bond at the ligation site.

See Protein splicing and Chemical ligation

Chitin

Chitin (C8H13O5N)n is a long-chain polymer of ''N''-acetylglucosamine, an amide derivative of glucose.

See Protein splicing and Chitin

Chlorophyta

Chlorophyta is a taxon of green algae informally called chlorophytes.

See Protein splicing and Chlorophyta

Chloroplast

A chloroplast is a type of membrane-bound organelle known as a plastid that conducts photosynthesis mostly in plant and algal cells.

See Protein splicing and Chloroplast

Choanoflagellate

The choanoflagellates are a group of free-living unicellular and colonial flagellate eukaryotes considered to be the closest living relatives of the animals.

See Protein splicing and Choanoflagellate

Chytridiomycota

Chytridiomycota are a division of zoosporic organisms in the kingdom Fungi, informally known as chytrids.

See Protein splicing and Chytridiomycota

Cryptococcus

Cryptococcus is a genus of fungi in the family Cryptococcaceae that includes both yeasts and filamentous species.

See Protein splicing and Cryptococcus

Cryptococcus gattii

Cryptococcus gattii, formerly known as Cryptococcus neoformans var.

See Protein splicing and Cryptococcus gattii

Cryptococcus neoformans

Cryptococcus neoformans is an encapsulated yeast belonging to the class Tremellomycetes and an obligate aerobe that can live in both plants and animals.

See Protein splicing and Cryptococcus neoformans

Cyanobacteria

Cyanobacteria, also called Cyanobacteriota or Cyanophyta, are a phylum of autotrophic gram-negative bacteria that can obtain biological energy via oxygenic photosynthesis.

See Protein splicing and Cyanobacteria

Cysteine

Cysteine (symbol Cys or C) is a semiessential proteinogenic amino acid with the formula.

See Protein splicing and Cysteine

Cystine

Cystine is the oxidized derivative of the amino acid cysteine and has the formula (SCH2CH(NH2)CO2H)2.

See Protein splicing and Cystine

Directionality (molecular biology)

Directionality, in molecular biology and biochemistry, is the end-to-end chemical orientation of a single strand of nucleic acid.

See Protein splicing and Directionality (molecular biology)

Dithiothreitol

Dithiothreitol (DTT) is an organosulfur compound with the formula.

See Protein splicing and Dithiothreitol

DNA polymerase III holoenzyme

DNA polymerase III holoenzyme is the primary enzyme complex involved in prokaryotic DNA replication.

See Protein splicing and DNA polymerase III holoenzyme

DnaB helicase

DnaB helicase is an enzyme in bacteria which opens the replication fork during DNA replication.

See Protein splicing and DnaB helicase

DnaE

DnaE, the gene product of dnaE, is the catalytic α subunit of DNA polymerase III, acting as a DNA polymerase.

See Protein splicing and DnaE

Drug development

Drug development is the process of bringing a new pharmaceutical drug to the market once a lead compound has been identified through the process of drug discovery.

See Protein splicing and Drug development

Elastin-like polypeptides

Elastin-like polypeptides (ELPs) are synthetic biopolymers with potential applications in the fields of cancer therapy, tissue scaffolding, metal recovery, and protein purification.

See Protein splicing and Elastin-like polypeptides

Enzyme inhibitor

An enzyme inhibitor is a molecule that binds to an enzyme and blocks its activity.

See Protein splicing and Enzyme inhibitor

Ester

In chemistry, an ester is a functional group derived from an acid (organic or inorganic) in which the hydrogen atom (H) of at least one acidic hydroxyl group of that acid is replaced by an organyl group.

See Protein splicing and Ester

Gene

In biology, the word gene has two meanings.

See Protein splicing and Gene

Gene product

A gene product is the biochemical material, either RNA or protein, resulting from the expression of a gene.

See Protein splicing and Gene product

Gene therapy

Gene therapy is a medical technology that aims to produce a therapeutic effect through the manipulation of gene expression or through altering the biological properties of living cells.

See Protein splicing and Gene therapy

Glomeromycota

Glomeromycota (often referred to as glomeromycetes, as they include only one class, Glomeromycetes) are one of eight currently recognized divisions within the kingdom Fungi, with approximately 230 described species.

See Protein splicing and Glomeromycota

Guanosine triphosphate

Guanosine-5'-triphosphate (GTP) is a purine nucleoside triphosphate.

See Protein splicing and Guanosine triphosphate

Hedgehog signaling pathway

The Hedgehog signaling pathway is a signaling pathway that transmits information to embryonic cells required for proper cell differentiation.

See Protein splicing and Hedgehog signaling pathway

Homing endonuclease

The homing endonucleases are a collection of endonucleases encoded either as freestanding genes within introns, as fusions with host proteins, or as self-splicing inteins.

See Protein splicing and Homing endonuclease

Homologous chromosome

A pair of homologous chromosomes, or homologs, is a set of one maternal and one paternal chromosome that pair up with each other inside a cell during fertilization.

See Protein splicing and Homologous chromosome

Homology (biology)

In biology, homology is similarity due to shared ancestry between a pair of structures or genes in different taxa.

See Protein splicing and Homology (biology)

Horizontal gene transfer

Horizontal gene transfer (HGT) or lateral gene transfer (LGT) is the movement of genetic material between organisms other than by the ("vertical") transmission of DNA from parent to offspring (reproduction).

See Protein splicing and Horizontal gene transfer

Hydrophobe

In chemistry, hydrophobicity is the physical property of a molecule that is seemingly repelled from a mass of water (known as a hydrophobe).

See Protein splicing and Hydrophobe

Imide

In organic chemistry, an imide is a functional group consisting of two acyl groups bound to nitrogen.

See Protein splicing and Imide

Intragenomic conflict

Intragenomic conflict refers to the evolutionary phenomenon where genes have phenotypic effects that promote their own transmission in detriment of the transmission of other genes that reside in the same genome.

See Protein splicing and Intragenomic conflict

Intron

An intron is any nucleotide sequence within a gene that is not expressed or operative in the final RNA product.

See Protein splicing and Intron

Ion transporter

In biology, an ion transporter is a transmembrane protein that moves ions (or other small molecules) across a biological membrane to accomplish many different biological functions, including cellular communication, maintaining homeostasis, energy production, etc.

See Protein splicing and Ion transporter

Iron–sulfur cluster biosynthesis

In biochemistry, the iron–sulfur cluster biosynthesis describes the components and processes involved in the biosynthesis of iron–sulfur proteins.

See Protein splicing and Iron–sulfur cluster biosynthesis

Mitochondrion

A mitochondrion is an organelle found in the cells of most eukaryotes, such as animals, plants and fungi.

See Protein splicing and Mitochondrion

Mycobacterium tuberculosis

Mycobacterium tuberculosis (M. tb), also known as Koch's bacillus, is a species of pathogenic bacteria in the family Mycobacteriaceae and the causative agent of tuberculosis.

See Protein splicing and Mycobacterium tuberculosis

N-terminus

The N-terminus (also known as the amino-terminus, NH2-terminus, N-terminal end or amine-terminus) is the start of a protein or polypeptide, referring to the free amine group (-NH2) located at the end of a polypeptide. Protein splicing and n-terminus are proteins.

See Protein splicing and N-terminus

Native chemical ligation

Native Chemical Ligation (NCL) is an important extension of the chemical ligation concept for constructing a larger polypeptide chain by the covalent condensation of two or more unprotected peptides segments.

See Protein splicing and Native chemical ligation

Neurospora crassa

Neurospora crassa is a type of red bread mold of the phylum Ascomycota.

See Protein splicing and Neurospora crassa

Nuclear magnetic resonance spectroscopy of proteins

Nuclear magnetic resonance spectroscopy of proteins (usually abbreviated protein NMR) is a field of structural biology in which NMR spectroscopy is used to obtain information about the structure and dynamics of proteins, and also nucleic acids, and their complexes.

See Protein splicing and Nuclear magnetic resonance spectroscopy of proteins

Nuclease

In biochemistry, a nuclease (also archaically known as nucleodepolymerase or polynucleotidase) is an enzyme capable of cleaving the phosphodiester bonds between nucleotides of nucleic acids.

See Protein splicing and Nuclease

Nucleophile

In chemistry, a nucleophile is a chemical species that forms bonds by donating an electron pair.

See Protein splicing and Nucleophile

Organism

An organism is defined in a medical dictionary as any living thing that functions as an individual.

See Protein splicing and Organism

Parasitism

Parasitism is a close relationship between species, where one organism, the parasite, lives on or inside another organism, the host, causing it some harm, and is adapted structurally to this way of life.

See Protein splicing and Parasitism

Peptide bond

In organic chemistry, a peptide bond is an amide type of covalent chemical bond linking two consecutive alpha-amino acids from C1 (carbon number one) of one alpha-amino acid and N2 (nitrogen number two) of another, along a peptide or protein chain.

See Protein splicing and Peptide bond

Peptide synthesis

In organic chemistry, peptide synthesis is the production of peptides, compounds where multiple amino acids are linked via amide bonds, also known as peptide bonds.

See Protein splicing and Peptide synthesis

Protein

Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Protein splicing and Protein are proteins.

See Protein splicing and Protein

Protein splicing

Protein splicing is an intramolecular reaction of a particular protein in which an internal protein segment (called an intein) is removed from a precursor protein with a ligation of C-terminal and N-terminal external proteins (called exteins) on both sides. Protein splicing and protein splicing are proteins.

See Protein splicing and Protein splicing

Protein tag

Protein tags are peptide sequences genetically grafted onto a recombinant protein.

See Protein splicing and Protein tag

Prp8

Prp8 refers to both the Prp8 protein and Prp8 gene.

See Protein splicing and Prp8

RecA

RecA is a 38 kilodalton protein essential for the repair and maintenance of DNA in bacteria.

See Protein splicing and RecA

RNA splicing

RNA splicing is a process in molecular biology where a newly-made precursor messenger RNA (pre-mRNA) transcript is transformed into a mature messenger RNA (mRNA).

See Protein splicing and RNA splicing

Saccharomyces cerevisiae

Saccharomyces cerevisiae (brewer's yeast or baker's yeast) is a species of yeast (single-celled fungal microorganisms).

See Protein splicing and Saccharomyces cerevisiae

Selfish genetic element

Selfish genetic elements (historically also referred to as selfish genes, ultra-selfish genes, selfish DNA, parasitic DNA and genomic outlaws) are genetic segments that can enhance their own transmission at the expense of other genes in the genome, even if this has no positive or a net negative effect on organismal fitness.

See Protein splicing and Selfish genetic element

Serine

Serine (symbol Ser or S) is an α-amino acid that is used in the biosynthesis of proteins.

See Protein splicing and Serine

Side chain

In organic chemistry and biochemistry, a side chain is a chemical group that is attached to a core part of the molecule called the "main chain" or backbone.

See Protein splicing and Side chain

Spliceosome

A spliceosome is a large ribonucleoprotein (RNP) complex found primarily within the nucleus of eukaryotic cells.

See Protein splicing and Spliceosome

The Selfish Gene

The Selfish Gene is a 1976 book on evolution by ethologist Richard Dawkins, in which the author builds upon the principal theory of George C. Williams's Adaptation and Natural Selection (1966).

See Protein splicing and The Selfish Gene

Thermoplasma acidophilum

Thermoplasma acidophilum is an archaeon, the type species of its genus.

See Protein splicing and Thermoplasma acidophilum

Thioester

In organic chemistry, thioesters are organosulfur compounds with the molecular structure.

See Protein splicing and Thioester

Three-domain system

The three-domain system is a taxonomic classification system that groups all cellular life into three domains, namely Archaea, Bacteria and Eukarya, introduced by Carl Woese, Otto Kandler and Mark Wheelis in 1990.

See Protein splicing and Three-domain system

Threonine

Threonine (symbol Thr or T) is an amino acid that is used in the biosynthesis of proteins.

See Protein splicing and Threonine

Transesterification

Transesterification is the process of exchanging the organic functional group R″ of an ester with the organic group R' of an alcohol.

See Protein splicing and Transesterification

V-ATPase

Vacuolar-type ATPase (V-ATPase) is a highly conserved evolutionarily ancient enzyme with remarkably diverse functions in eukaryotic organisms.

See Protein splicing and V-ATPase

Vacuole

A vacuole is a membrane-bound organelle which is present in plant and fungal cells and some protist, animal, and bacterial cells.

See Protein splicing and Vacuole

Virus

A virus is a submicroscopic infectious agent that replicates only inside the living cells of an organism.

See Protein splicing and Virus

Wild type

The wild type (WT) is the phenotype of the typical form of a species as it occurs in nature.

See Protein splicing and Wild type

Yeast

Yeasts are eukaryotic, single-celled microorganisms classified as members of the fungus kingdom.

See Protein splicing and Yeast

Zygomycota

Zygomycota, or zygote fungi, is a former division or phylum of the kingdom Fungi.

See Protein splicing and Zygomycota

References

[1] https://en.wikipedia.org/wiki/Protein_splicing

Also known as Expressed protein ligation, Extein, Exteins, Intein, Inteins, Protein ligation.

, Imide, Intragenomic conflict, Intron, Ion transporter, Iron–sulfur cluster biosynthesis, Mitochondrion, Mycobacterium tuberculosis, N-terminus, Native chemical ligation, Neurospora crassa, Nuclear magnetic resonance spectroscopy of proteins, Nuclease, Nucleophile, Organism, Parasitism, Peptide bond, Peptide synthesis, Protein, Protein splicing, Protein tag, Prp8, RecA, RNA splicing, Saccharomyces cerevisiae, Selfish genetic element, Serine, Side chain, Spliceosome, The Selfish Gene, Thermoplasma acidophilum, Thioester, Three-domain system, Threonine, Transesterification, V-ATPase, Vacuole, Virus, Wild type, Yeast, Zygomycota.